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公开(公告)号：US20110295151A1
公开(公告)日：2011-12-01
申请号：US13104282
申请日：2011-05-10
申请人： Gregory J. Bakos , Edward G. Chekan , Denzel Z. Herrera-Davis , Jason L. Harris , Gary L. Long , Rudolph H. Nobis , Mark S. Ortiz , Mark D. Overmyer , David N. Plescia , Randy J. Seeley , William B. Weisenburgh, II , Tamara S. Vetro Widenhouse , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Gregory J. Bakos , Edward G. Chekan , Denzel Z. Herrera-Davis , Jason L. Harris , Gary L. Long , Rudolph H. Nobis , Mark S. Ortiz , Mark D. Overmyer , David N. Plescia , Randy J. Seeley , William B. Weisenburgh, II , Tamara S. Vetro Widenhouse , Mark S. Zeiner , Andrew M. Zwolinski
IPC分类号： A61M37/00 , A61P3/00 , A61K9/00 , A61F2/04 , A61K49/00 , A61P3/04 , A61B10/02 , A61M5/00 , A61K35/55 , A61K9/20
CPC分类号： C12N5/0679 , A61K35/12 , A61K35/38 , A61L27/14 , A61L27/3882 , A61L27/58 , A61L31/04 , A61L31/148 , A61L31/16 , A61L2300/64
摘要： L-cells may be introduced in the gastrointestinal tract. L-cells are used in the digestive process to produce a more efficient and lasting means of regulating feelings of satiation in a patient. Desired metabolic effects may be achieved by manipulating L-cells via delivery sites, frequency of delivery, or type of biological substance delivered.
摘要翻译： L细胞可能被引入胃肠道。 L细胞用于消化过程，以产生更有效和持久的调节患者饱腹感的手段。 所需的代谢作用可以通过经由递送部位操纵L细胞，递送频率或递送的生物物质的类型来实现。
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2.发明申请Intestinal Brake Inducing Intraluminal Therapeutic Substance Eluting Devices and Methods 审中-公开肠制动诱导腔内治疗物质洗脱装置及方法公开(公告)号：US20110295178A1
公开(公告)日：2011-12-01
申请号：US13104321
申请日：2011-05-10
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Gregory J. Bakos , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Suzanne Thompson , Richard W. Timm , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Gregory J. Bakos , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Suzanne Thompson , Richard W. Timm , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
IPC分类号： A61M5/00
CPC分类号： A61F5/0079 , A61K9/0065 , A61M5/14276 , A61M31/002 , A61M39/0208 , A61M2210/106 , A61M2210/1064
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices may be accomplished via stabilized implantable systems and ingestible pills. In one aspect, a method of inducing satiety includes implanting an implant within a lumen of a gastrointestinal tract and retaining a portion of chyme that flows by the implant within a body of the implant. The method further involves re-releasing the retained chyme from the implant into the gastrointestinal tract at a predetermined rate slower than a rate caused by natural peristalsis.
摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置可以通过稳定的可植入系统和可摄取的药丸来实现。 一方面，一种诱导饱腹感的方法包括将植入物植入胃肠道的内腔中，并且将植入物流动的部分保持在植入物的体内。 该方法还包括以比由天然蠕动引起的速率慢的预定速率将留置的食糜从植入物再释放到胃肠道中。
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3.发明申请公开(公告)号：US20110295054A1
公开(公告)日：2011-12-01
申请号：US13104095
申请日：2011-05-10
申请人： Jeffrey L. Aldridge , Gregory J. Bakos , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Lucas B. Elmer , Jason L. Harris , Christopher J. Hess , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Michael J. Stokes , Foster B. Stulen , Suzanne Thompson , Richard W. Timm , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Jeffrey L. Aldridge , Gregory J. Bakos , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Lucas B. Elmer , Jason L. Harris , Christopher J. Hess , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Michael J. Stokes , Foster B. Stulen , Suzanne Thompson , Richard W. Timm , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , Mark S. Zeiner , Andrew M. Zwolinski
CPC分类号： A61F5/005 , A61F5/0003 , A61F5/0013 , A61M25/007 , A61M25/04 , A61M31/00 , A61M37/0015
摘要： Methods described herein involve introducing a nasogastric tube into a patient, connecting the nasogastric tube with a reservoir, anchoring the nasogastric tube with the nasal cavity, and introducing a substance into the reservoir through the nasogastric tube.
摘要翻译： 本文描述的方法包括将鼻胃管引入患者体内，将鼻胃管与储器连接，将鼻胃管与鼻腔固定，并通过鼻胃管将物质引入储液器。
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4.发明申请公开(公告)号：US20110295337A1
公开(公告)日：2011-12-01
申请号：US13105262
申请日：2011-05-11
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Edward G. Chekan , Sean P. Conlon , Michael S. Cropper , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Kevin L. Houser , John V. Hunt , Gary L. Long , Prasanna Malaviya , Amy L. Marcotte , Rudolph H. Nobis , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , David N. Plescia , Galen C. Robertson , Randy J. Seeley , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , Richard W. Timm , James W. Voegele , William B. Weisenburgh, II , James A. Woodard, JR. , David C. Yates , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Edward G. Chekan , Sean P. Conlon , Michael S. Cropper , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Kevin L. Houser , John V. Hunt , Gary L. Long , Prasanna Malaviya , Amy L. Marcotte , Rudolph H. Nobis , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , David N. Plescia , Galen C. Robertson , Randy J. Seeley , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , Richard W. Timm , James W. Voegele , William B. Weisenburgh, II , James A. Woodard, JR. , David C. Yates , Andrew M. Zwolinski
IPC分类号： A61N1/36
CPC分类号： A61N1/00 , A61F5/0026 , A61N1/0509 , A61N1/327 , A61N1/36007
摘要： A method for regulating hormone production comprises placing at least one electrode in a gastrointestinal tract of a patient and recording an electrical signal during a preselected event produced by the gastrointestinal tract. The method further involves the steps of storing the electrical signal, and playing back the electrical signal by activating the electrode during the absence of the preselected event.
摘要翻译： 用于调节激素产生的方法包括将至少一个电极放置在患者的胃肠道中，并在由胃肠道产生的预选事件期间记录电信号。 该方法还包括存储电信号的步骤，以及在没有预选事件期间激活电极来播放电信号。
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5.发明申请Intestinal Brake Inducing Intraluminal Therapeutic Substance Eluting Devices and Methods 有权肠制动诱导腔内治疗物质洗脱装置及方法公开(公告)号：US20110295185A1
公开(公告)日：2011-12-01
申请号：US13104313
申请日：2011-05-10
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
CPC分类号： A61M31/002 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F2002/045 , A61K9/0065 , A61M5/14276 , A61M39/0208 , A61M2210/106 , A61M2210/1064 , A61N1/0509 , A61N1/36007 , A61N1/37205
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract.
摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施方案中，产生饱腹感的方法包括以下步骤：进入患者的胃肠道并植入肠内治疗物质洗脱植入物。 植入物能够洗脱选自营养物，特定饱腹感生物活性物质，胰腺多肽，游离脂肪酸，缩胆囊素，氨基酸，谷氨酰胺，脂质，亚油酸或组合中的至少一种的饱腹感受物质 从植入物到胃肠道。
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6.发明申请INTESTINAL BRAKE INDUCING INTRALUMINAL THERAPEUTIC SUBSTANCE ELUTING DEVICES AND METHODS 有权INTESTINAL BRAKE INDING IN INTRALUMINAL THERAPEUTIC THEAPEUTIC TYSTURE ELDTING ELTERTING DEVICES AND METHODS公开(公告)号：US20110295180A1
公开(公告)日：2011-12-01
申请号：US13105029
申请日：2011-05-11
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F5/0079 , A61F2002/045
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient.
摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施方案中，可植入系统包括将治疗物质递送到患者胃肠道内的目标位置的装置，以便开始肠促动作用，其将促进饱腹感，并刺激患者多余的体重减轻。
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7.发明授权Intestinal brake inducing intraluminal therapeutic substance eluting devices and methods 有权肠内制动诱导管腔内治疗物质洗脱装置及方法公开(公告)号：US08876761B2
公开(公告)日：2014-11-04
申请号：US13104313
申请日：2011-05-10
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
IPC分类号： A61M31/00 , A61K9/00 , A61M5/142 , A61F5/00 , A61N1/05 , A61M39/02 , A61F2/04 , A61N1/36 , A61N1/372
CPC分类号： A61M31/002 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F2002/045 , A61K9/0065 , A61M5/14276 , A61M39/0208 , A61M2210/106 , A61M2210/1064 , A61N1/0509 , A61N1/36007 , A61N1/37205
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract.
摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施方案中，产生饱腹感的方法包括以下步骤：进入患者的胃肠道并植入肠内治疗物质洗脱植入物。 植入物能够洗脱选自营养物，特定饱腹感生物活性物质，胰腺多肽，游离脂肪酸，缩胆囊素，氨基酸，谷氨酰胺，脂质，亚油酸或组合中的至少一种的饱腹感受物质 从植入物到胃肠道。
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8.发明授权Intestinal brake inducing intraluminal therapeutic substance eluting devices and methods 有权肠内制动诱导管腔内治疗物质洗脱装置及方法公开(公告)号：US08603023B2
公开(公告)日：2013-12-10
申请号：US13105029
申请日：2011-05-11
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
CPC分类号： A61F5/0076 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F5/0079 , A61F2002/045
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient.
摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施方案中，可植入系统包括将治疗物质递送到患者胃肠道内的目标位置的装置，以便开始肠促动作用，其将促进饱腹感，并刺激患者多余的体重减轻。
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公开(公告)号：US20110295057A1
公开(公告)日：2011-12-01
申请号：US13105001
申请日：2011-05-11
申请人： Jeffrey L. Aldridge , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , John V. Hunt , Prasanna Malaviya , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Galen C. Robertson , Frederick E. Shelton, IV , Foster B. Stulen , Suzanne Thompson , James W. Voegele , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , David C. Yates , Mark S. Zeiner
发明人： Jeffrey L. Aldridge , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , John V. Hunt , Prasanna Malaviya , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Galen C. Robertson , Frederick E. Shelton, IV , Foster B. Stulen , Suzanne Thompson , James W. Voegele , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , David C. Yates , Mark S. Zeiner
IPC分类号： A61F2/04
CPC分类号： A61F5/0083 , A61F5/003 , A61F5/0033 , A61F5/0036 , A61F5/004 , A61F5/0043 , A61F5/005 , A61F5/0053 , A61F5/0056 , A61F5/0073 , A61F5/0086
摘要： Devices and methods for modifying stomach volume include the formation of intragastric slots for wrapping one or more portions of the fundus therethrough with minimal interference with nerves and vasculature flow. Intragastric space occupying devices expand with environmental changes brought about by natural conditions inherent to the digestive cycle such as with changes in pH. Extragastric volume occupying balloons are placed into folded stomach sections. The balloons are fluidly coupled to external gastric filling devices. In yet another set of embodiments, methods and devices provide adjustable gastric volume reduction fundal wraps. In one embodiment, a device is placed in the fundus for Nissen fundoplication and permits postoperative adjustment to reach desired weight loss. Intragastric and extragastric balloons are optionally incorporated.
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公开(公告)号：US20110295056A1
公开(公告)日：2011-12-01
申请号：US13104223
申请日：2011-05-10
申请人： Jeffrey L. Aldridge , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , John V. Hunt , Prasanna Malaviya , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Galen C. Robertson , Frederick E. Shelton, IV , Foster B. Stulen , Suzanne Thompson , James W. Voegele , Lauren S. Weaner , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , David C. Yates , Mark S. Zeiner
发明人： Jeffrey L. Aldridge , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , John V. Hunt , Prasanna Malaviya , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Galen C. Robertson , Frederick E. Shelton, IV , Foster B. Stulen , Suzanne Thompson , James W. Voegele , Lauren S. Weaner , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , David C. Yates , Mark S. Zeiner
IPC分类号： A61F2/04
CPC分类号： A61F5/0083 , A61B17/00234 , A61B17/064 , A61B17/12136 , A61B17/12159 , A61B17/1355 , A61B2017/00035 , A61B2017/00557 , A61B2017/00632 , A61B2017/00818 , A61B2017/00898 , A61B2017/1142 , A61F5/004 , A61F5/0056
摘要： Devices and methods for modifying stomach volume include the formation of intragastric slots for wrapping one or more portions of the fundus therethrough with minimal interference with nerves and vasculature flow. Intragastric space occupying devices expand with environmental changes brought about by natural conditions inherent to the digestive cycle such as with changes in pH. Extragastric volume occupying balloons are placed into folded stomach sections. The balloons are fluidly coupled to external gastric filling devices. In yet another set of embodiments, methods and devices provide adjustable gastric volume reduction fundal wraps. In one embodiment, a device is placed in the fundus for Nissen fundoplication and permits postoperative adjustment to reach desired weight loss. Intragastric and extragastric balloons are optionally incorporated.
摘要翻译： 用于改变胃体积的装置和方法包括形成胃内狭槽，用于以最小的神经和脉管系统流动的干扰来包裹眼底的一个或多个部分。 内部空间占据装置随着消化循环固有的自然条件（如pH变化）带来的环境变化而扩大。 腹腔积气囊放置在折叠的胃部。 气囊流体地联接到外部胃灌注装置。 在另一组实施方案中，方法和装置提供可调节的胃体积减少基底包裹。 在一个实施例中，将装置放置在眼底以进行尼森眼底切开术，并允许术后调整以达到期望的体重减轻。 肠内和胃内气囊任选并入。
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