-
1.发明授权Intestinal brake inducing intraluminal therapeutic substance eluting devices and methods 有权肠内制动诱导管腔内治疗物质洗脱装置及方法公开(公告)号：US08603023B2
公开(公告)日：2013-12-10
申请号：US13105029
申请日：2011-05-11
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
CPC分类号： A61F5/0076 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F5/0079 , A61F2002/045
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient.
摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施方案中，可植入系统包括将治疗物质递送到患者胃肠道内的目标位置的装置，以便开始肠促动作用，其将促进饱腹感，并刺激患者多余的体重减轻。
-
2.发明申请INTESTINAL BRAKE INDUCING INTRALUMINAL THERAPEUTIC SUBSTANCE ELUTING DEVICES AND METHODS 有权INTESTINAL BRAKE INDING IN INTRALUMINAL THERAPEUTIC THEAPEUTIC TYSTURE ELDTING ELTERTING DEVICES AND METHODS公开(公告)号：US20110295180A1
公开(公告)日：2011-12-01
申请号：US13105029
申请日：2011-05-11
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Thomas W. Huitema , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Foster B. Stulen , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
IPC分类号： A61F2/04
CPC分类号： A61F5/0076 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F5/0079 , A61F2002/045
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient.
摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施方案中，可植入系统包括将治疗物质递送到患者胃肠道内的目标位置的装置，以便开始肠促动作用，其将促进饱腹感，并刺激患者多余的体重减轻。
-
3.发明授权Intestinal brake inducing intraluminal therapeutic substance eluting devices and methods 有权肠内制动诱导管腔内治疗物质洗脱装置及方法公开(公告)号：US08876761B2
公开(公告)日：2014-11-04
申请号：US13104313
申请日：2011-05-10
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, Jr. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, Jr. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
IPC分类号： A61M31/00 , A61K9/00 , A61M5/142 , A61F5/00 , A61N1/05 , A61M39/02 , A61F2/04 , A61N1/36 , A61N1/372
CPC分类号： A61M31/002 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F2002/045 , A61K9/0065 , A61M5/14276 , A61M39/0208 , A61M2210/106 , A61M2210/1064 , A61N1/0509 , A61N1/36007 , A61N1/37205
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract.
摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施方案中，产生饱腹感的方法包括以下步骤：进入患者的胃肠道并植入肠内治疗物质洗脱植入物。 植入物能够洗脱选自营养物，特定饱腹感生物活性物质，胰腺多肽，游离脂肪酸，缩胆囊素，氨基酸，谷氨酰胺，脂质，亚油酸或组合中的至少一种的饱腹感受物质 从植入物到胃肠道。
-
4.发明申请Intestinal Brake Inducing Intraluminal Therapeutic Substance Eluting Devices and Methods 有权肠制动诱导腔内治疗物质洗脱装置及方法公开(公告)号：US20110295185A1
公开(公告)日：2011-12-01
申请号：US13104313
申请日：2011-05-10
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Sean P. Conlon , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , Prasanna Malaviya , Glenda C. Marsh , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , James W. Voegele , Lauren S. Weaner , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
CPC分类号： A61M31/002 , A61F2/04 , A61F5/0013 , A61F5/0026 , A61F2002/045 , A61K9/0065 , A61M5/14276 , A61M39/0208 , A61M2210/106 , A61M2210/1064 , A61N1/0509 , A61N1/36007 , A61N1/37205
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems and ingestible pills. In one embodiment, a method of producing satiety comprising the steps of accessing a gastrointestinal tract of a patient and implanting an intraintestinal therapeutic substance eluting implant. The implant is capable of eluting a satiety inducing substance selected from at least one of a nutrient, a specific satiety inducing bio-active substance, pancreatic polypeptides, free fatty acids, cholecystokinin, amino acids, glutamine, lipids, linoleic acid, or a combination thereof, from the implant into the gastrointestinal tract.
摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置通过稳定的可植入系统和可摄取的药丸来实现。 在一个实施方案中，产生饱腹感的方法包括以下步骤：进入患者的胃肠道并植入肠内治疗物质洗脱植入物。 植入物能够洗脱选自营养物，特定饱腹感生物活性物质，胰腺多肽，游离脂肪酸，缩胆囊素，氨基酸，谷氨酰胺，脂质，亚油酸或组合中的至少一种的饱腹感受物质 从植入物到胃肠道。
-
5.发明申请Intestinal Brake Inducing Intraluminal Therapeutic Substance Eluting Devices and Methods 审中-公开肠制动诱导腔内治疗物质洗脱装置及方法公开(公告)号：US20110295178A1
公开(公告)日：2011-12-01
申请号：US13104321
申请日：2011-05-10
申请人： Thomas E. Albrecht , Jeffrey L. Aldridge , Gregory J. Bakos , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Suzanne Thompson , Richard W. Timm , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
发明人： Thomas E. Albrecht , Jeffrey L. Aldridge , Gregory J. Bakos , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , Christopher J. Hess , John V. Hunt , Prasanna Malaviya , Mark S. Ortiz , Mark D. Overmyer , Alessandro Pastorelli , Galen C. Robertson , Frederick E. Shelton, IV , Michael J. Stokes , Suzanne Thompson , Richard W. Timm , James W. Voegele , William B. Weisenburgh, II , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , James A. Woodard, JR. , David C. Yates , Mark S. Zeiner , Andrew M. Zwolinski
IPC分类号： A61M5/00
CPC分类号： A61F5/0079 , A61K9/0065 , A61M5/14276 , A61M31/002 , A61M39/0208 , A61M2210/106 , A61M2210/1064
摘要： Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices may be accomplished via stabilized implantable systems and ingestible pills. In one aspect, a method of inducing satiety includes implanting an implant within a lumen of a gastrointestinal tract and retaining a portion of chyme that flows by the implant within a body of the implant. The method further involves re-releasing the retained chyme from the implant into the gastrointestinal tract at a predetermined rate slower than a rate caused by natural peristalsis.
摘要翻译： 方法和装置产生肠道制动效果，是非侵入性的或微创的，并且可以是可逆的。 这些方法和装置可以通过稳定的可植入系统和可摄取的药丸来实现。 一方面，一种诱导饱腹感的方法包括将植入物植入胃肠道的内腔中，并且将植入物流动的部分保持在植入物的体内。 该方法还包括以比由天然蠕动引起的速率慢的预定速率将留置的食糜从植入物再释放到胃肠道中。
-
公开(公告)号：US20110295057A1
公开(公告)日：2011-12-01
申请号：US13105001
申请日：2011-05-11
申请人： Jeffrey L. Aldridge , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , John V. Hunt , Prasanna Malaviya , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Galen C. Robertson , Frederick E. Shelton, IV , Foster B. Stulen , Suzanne Thompson , James W. Voegele , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , David C. Yates , Mark S. Zeiner
发明人： Jeffrey L. Aldridge , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , John V. Hunt , Prasanna Malaviya , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Galen C. Robertson , Frederick E. Shelton, IV , Foster B. Stulen , Suzanne Thompson , James W. Voegele , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , David C. Yates , Mark S. Zeiner
IPC分类号： A61F2/04
CPC分类号： A61F5/0083 , A61F5/003 , A61F5/0033 , A61F5/0036 , A61F5/004 , A61F5/0043 , A61F5/005 , A61F5/0053 , A61F5/0056 , A61F5/0073 , A61F5/0086
摘要： Devices and methods for modifying stomach volume include the formation of intragastric slots for wrapping one or more portions of the fundus therethrough with minimal interference with nerves and vasculature flow. Intragastric space occupying devices expand with environmental changes brought about by natural conditions inherent to the digestive cycle such as with changes in pH. Extragastric volume occupying balloons are placed into folded stomach sections. The balloons are fluidly coupled to external gastric filling devices. In yet another set of embodiments, methods and devices provide adjustable gastric volume reduction fundal wraps. In one embodiment, a device is placed in the fundus for Nissen fundoplication and permits postoperative adjustment to reach desired weight loss. Intragastric and extragastric balloons are optionally incorporated.
-
公开(公告)号：US20110295056A1
公开(公告)日：2011-12-01
申请号：US13104223
申请日：2011-05-10
申请人： Jeffrey L. Aldridge , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , John V. Hunt , Prasanna Malaviya , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Galen C. Robertson , Frederick E. Shelton, IV , Foster B. Stulen , Suzanne Thompson , James W. Voegele , Lauren S. Weaner , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , David C. Yates , Mark S. Zeiner
发明人： Jeffrey L. Aldridge , Michael S. Cropper , Denzel Z. Herrera-Davis , Daniel F. Dlugos, JR. , Jason L. Harris , John V. Hunt , Prasanna Malaviya , Jeffrey D. Messerly , Mark S. Ortiz , Mark D. Overmyer , Galen C. Robertson , Frederick E. Shelton, IV , Foster B. Stulen , Suzanne Thompson , James W. Voegele , Lauren S. Weaner , Christopher W. Widenhouse , Tamara S. Vetro Widenhouse , David C. Yates , Mark S. Zeiner
IPC分类号： A61F2/04
CPC分类号： A61F5/0083 , A61B17/00234 , A61B17/064 , A61B17/12136 , A61B17/12159 , A61B17/1355 , A61B2017/00035 , A61B2017/00557 , A61B2017/00632 , A61B2017/00818 , A61B2017/00898 , A61B2017/1142 , A61F5/004 , A61F5/0056
摘要： Devices and methods for modifying stomach volume include the formation of intragastric slots for wrapping one or more portions of the fundus therethrough with minimal interference with nerves and vasculature flow. Intragastric space occupying devices expand with environmental changes brought about by natural conditions inherent to the digestive cycle such as with changes in pH. Extragastric volume occupying balloons are placed into folded stomach sections. The balloons are fluidly coupled to external gastric filling devices. In yet another set of embodiments, methods and devices provide adjustable gastric volume reduction fundal wraps. In one embodiment, a device is placed in the fundus for Nissen fundoplication and permits postoperative adjustment to reach desired weight loss. Intragastric and extragastric balloons are optionally incorporated.
摘要翻译： 用于改变胃体积的装置和方法包括形成胃内狭槽，用于以最小的神经和脉管系统流动的干扰来包裹眼底的一个或多个部分。 内部空间占据装置随着消化循环固有的自然条件（如pH变化）带来的环境变化而扩大。 腹腔积气囊放置在折叠的胃部。 气囊流体地联接到外部胃灌注装置。 在另一组实施方案中，方法和装置提供可调节的胃体积减少基底包裹。 在一个实施例中，将装置放置在眼底以进行尼森眼底切开术，并允许术后调整以达到期望的体重减轻。 肠内和胃内气囊任选并入。
-
公开(公告)号：US10123798B2
公开(公告)日：2018-11-13
申请号：US13433141
申请日：2012-03-28
申请人： Chester O. Baxter, III , Frederick E. Shelton, IV , Charles J. Scheib , Christopher W. Widenhouse , William B. Weisenburgh, II , John L. Stammen , Mark H. Ransick , Stephanie A. Mutchler , Gary W. Knight , Michael S. Cropper , Sean P. Conlon , Jeffrey S. Swayze
发明人： Chester O. Baxter, III , Frederick E. Shelton, IV , Charles J. Scheib , Christopher W. Widenhouse , William B. Weisenburgh, II , John L. Stammen , Mark H. Ransick , Stephanie A. Mutchler , Gary W. Knight , Michael S. Cropper , Sean P. Conlon , Jeffrey S. Swayze
IPC分类号： A61B17/072 , A61B17/00 , A61B17/064 , A61B17/115 , A61B17/29 , A61B17/32
摘要： A tissue thickness compensator may generally comprise a first layer comprising a first biocompatible material sealingly enclosed in a water impermeable material and a second layer comprising a second biocompatible material comprising at least one encapsulation, wherein the first biocompatible material expands when contacted with a fluid. The tissue thickness compensator may comprise a haemostatic agent, an anti-inflammatory agent, an antibiotic agent, anti-microbial agent, an anti-adhesion agent, an anti-coagulant agent, a medicament, and/or pharmaceutically active agent. The encapsulation may comprise a biodegradable material to degrade in vivo and/or in situ. The tissue thickness compensator may comprise a hydrogel. The reaction product may comprise a fluid-swellable composition. Articles of manufacture comprising the tissue thickness compensator and methods of making and using the tissue thickness compensator are also described.
-
9.发明申请公开(公告)号：US20120241493A1
公开(公告)日：2012-09-27
申请号：US13433141
申请日：2012-03-28
申请人： Chester O. Baxter, III , Frederick E. Shelton, IV , Charles J. Scheib , Christopher W. Widenhouse , William B. Weisenburgh, II , John L. Stammen , Mark H. Ransick , Stephanie A. Mutchler , Gary W. Knight , Michael S. Cropper , Sean P. Conlon , Jeffrey S. Swayze
发明人： Chester O. Baxter, III , Frederick E. Shelton, IV , Charles J. Scheib , Christopher W. Widenhouse , William B. Weisenburgh, II , John L. Stammen , Mark H. Ransick , Stephanie A. Mutchler , Gary W. Knight , Michael S. Cropper , Sean P. Conlon , Jeffrey S. Swayze
IPC分类号： A61B17/068 , B05D7/00
CPC分类号： A61B17/07207 , A61B17/00491 , A61B17/0643 , A61B17/0644 , A61B17/072 , A61B17/07292 , A61B17/1155 , A61B17/2909 , A61B2017/00004 , A61B2017/00314 , A61B2017/00327 , A61B2017/00477 , A61B2017/00495 , A61B2017/00526 , A61B2017/0053 , A61B2017/00818 , A61B2017/00862 , A61B2017/00884 , A61B2017/00889 , A61B2017/00893 , A61B2017/00898 , A61B2017/07228 , A61B2017/07235 , A61B2017/07242 , A61B2017/0725 , A61B2017/07257 , A61B2017/07264 , A61B2017/07271 , A61B2017/07278 , A61B2017/07285 , A61B2017/2908 , A61B2017/2919 , A61B2017/2923 , A61B2017/2927 , A61B2017/2933 , A61B2017/2936 , A61B2017/2946 , A61B2017/320052 , F04C2270/0421
摘要： A tissue thickness compensator may generally comprise a first layer comprising a first biocompatible material sealingly enclosed in a water impermeable material and a second layer comprising a second biocompatible material comprising at least one encapsulation, wherein the first biocompatible material expands when contacted with a fluid. The tissue thickness compensator may comprise a haemostatic agent, an anti-inflammatory agent, an antibiotic agent, anti-microbial agent, an anti-adhesion agent, an anti-coagulant agent, a medicament, and/or pharmaceutically active agent. The encapsulation may comprise a biodegradable material to degrade in vivo and/or in situ. The tissue thickness compensator may comprise a hydrogel. The reaction product may comprise a fluid-swellable composition. Articles of manufacture comprising the tissue thickness compensator and methods of making and using the tissue thickness compensator are also described.
摘要翻译： 组织厚度补偿器通常可以包括密封地封闭在不透水材料中的第一生物相容性材料的第一层和包含至少一种封装的第二生物相容性材料的第二层，其中当与流体接触时第一生物相容性材料膨胀。 组织厚度补偿器可以包括止血剂，抗炎剂，抗生素剂，抗微生物剂，抗粘连剂，抗凝剂，药物和/或药物活性剂。 包封可以包括在体内和/或原位降解的可生物降解的材料。 组织厚度补偿器可以包括水凝胶。 反应产物可以包含流体可溶胀组合物。 还描述了包括组织厚度补偿器的制品以及制造和使用组织厚度补偿器的方法。
-
公开(公告)号：US08727964B2
公开(公告)日：2014-05-20
申请号：US12562279
申请日：2009-09-18
申请人： Daniel F. Dlugos, Jr. , Thomas E. Adams , Randal T. Byrum , Sean P. Conlon , Rocco Crivelli , Dean L. Garner , Alec J. Ginggen , Wells D. Haberstich , Geoffrey C. Hueil , Donna L. Korvick , David T. Krumanaker , Timothy P. Lessek , Amy L. Marcotte , Jeffrey D. Messerly , Kyle P. Moore , Daniel J. Mumaw , Anil K. Nalagatla , Mark S. Ortiz , Frederick E. Shelton, IV , Bret W. Smith , Jeffrey S. Swayze , Patrick J. Swindon , Eric W. Thompson , Mark Tsonton , Lauren S. Weaner , Christopher W. Widenhouse , Scott A. Woodruff
发明人： Daniel F. Dlugos, Jr. , Thomas E. Adams , Randal T. Byrum , Sean P. Conlon , Rocco Crivelli , Dean L. Garner , Alec J. Ginggen , Wells D. Haberstich , Geoffrey C. Hueil , Donna L. Korvick , David T. Krumanaker , Timothy P. Lessek , Amy L. Marcotte , Jeffrey D. Messerly , Kyle P. Moore , Daniel J. Mumaw , Anil K. Nalagatla , Mark S. Ortiz , Frederick E. Shelton, IV , Bret W. Smith , Jeffrey S. Swayze , Patrick J. Swindon , Eric W. Thompson , Mark Tsonton , Lauren S. Weaner , Christopher W. Widenhouse , Scott A. Woodruff
CPC分类号： A61F5/0053 , A61F2/0036 , A61F5/003 , A61F5/0033 , A61F5/0056 , A61F5/0059
摘要： An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. The elongated member has a compressible ventral surface and a substantially rigid dorsal periphery, wherein the elongated member includes a fluid bladder positioned along the ventral surface. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A drive element is associated with and engages the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct. Alternate embodiments are also disclosed.
摘要翻译： 用于调节患者器官或管道的功能的装置包括具有第一端和第二端的细长构件。 细长构件具有可压缩的腹侧表面和基本刚性的背侧周边，其中细长构件包括沿腹侧面定位的流体囊。 紧固件设置在细长构件的第一端上。 紧固件构造成接合细长构件的第二端，使得细长构件围绕器官或管道形成环。 张力元件设置成在细长构件内移动。 驱动元件与张力元件相关联并与其接合，用于使张力元件控制由细长构件施加的抗张力抵靠患者身体器官或管道的张力。 还公开了替代实施例。
-
-
-
-
-
-
-
-
-
搜索结果
84 条记录 (耗时 0.094 秒)
