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公开(公告)号：US5948672A
公开(公告)日：1999-09-07
申请号：US389423
申请日：1995-02-14
申请人： Grethe Rasmussen , Jan M.o slashed.ller Mikkelsen , Martin Schulein , Shamkant Anant Patkar , Fred Hagen , Carsten Mailand Hjort , Sven Hastrup
发明人： Grethe Rasmussen , Jan M.o slashed.ller Mikkelsen , Martin Schulein , Shamkant Anant Patkar , Fred Hagen , Carsten Mailand Hjort , Sven Hastrup
IPC分类号： C12N15/09 , C11D3/386 , C12N1/15 , C12N1/19 , C12N9/24 , C12N9/42 , C12N15/56 , C12N15/80 , C12Q1/68 , C12R1/645 , C12R1/69 , C12R1/77 , C12R1/865 , C12S3/04 , C12S3/08 , D06L4/40 , D06M16/00 , D06M101/00 , D06M101/02 , D06M101/06 , D06P5/00 , D06P5/08 , D06P5/13 , D06P5/15 , D21C5/02 , D21H11/20 , D21H17/00 , D21H21/10 , D21C1/00 , D21C3/00
CPC分类号： C12Q1/6895 , C11D3/38645 , C12N15/80 , C12N9/2437 , C12Y302/01004 , C12Y302/01039 , C12Y302/01091 , D06M16/003 , D06P5/137 , D06P5/158 , D21H17/005 , D21H21/10
摘要： A cellulase preparation consisting essentially of a homogeneous endoglucanase component which is immunoreactive with an antibody raised against a highly purified .about.43 kD endoglucanase derived from Humicola insolens, DSM 1800, or which is homogeneous to said .about.43 kD endoglucanase, may be employed in the treatment cellulose-containing fabrics for harshness reduction or color clarification or to provide a localized variation in the color of such fabrics, or it may be employed in the treatment of paper pulp.
摘要翻译： 基本上由均匀的内切葡聚糖酶组分组成的纤维素酶制剂可以用于与针对来自Humicola insolens DSM 1800的高度纯化的差异43kD内切葡聚糖或与所述差异43kD内切葡聚糖酶相同的抗体产生免疫反应性的均一内切葡聚糖酶组分 含有纤维素的织物用于粗糙度降低或颜色澄清或提供这种织物的颜色的局部变化，或者可以用于纸浆的处理。
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公开(公告)号：US5686593A
公开(公告)日：1997-11-11
申请号：US479939
申请日：1995-06-07
IPC分类号： C12N1/19 , C12N9/42 , C12N15/09 , C12R1/645 , C12R1/77 , C07H21/02 , A61K38/47 , C07H21/04 , G01N33/53
CPC分类号： C12N9/2437 , C12Y302/01004 , C12Y302/01091
摘要： The present invention relates to cellulose- or hemicellulose-degrading enzymes which is derivable from a fungus other than Trichoderma or Phanerochaete, and which comprises a carbohydrate binding domain homologous to a terminal A region of Trichoderma reesei cellulases, which carbohydrate binding domain comprises the following amino acid sequence. ##STR1## or a subsequence thereof capable of effecting binding of the enzyme to an insoluble cellulosic or hemicellulosic substrate.
摘要翻译： 本发明涉及可从除木霉属或Phanerochaete之外的真菌衍生的纤维素或半纤维素降解酶，其包含与里氏木霉纤维素酶的末端A区同源的碳水化合物结合结构域，所述碳水化合物结合结构域包含以下氨基 酸序列。 将酶与不溶性纤维素或半纤维素基质结合起来。
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公开(公告)号：US06423524B1
公开(公告)日：2002-07-23
申请号：US09189028
申请日：1998-11-10
申请人： Fred Hagen , Carsten Mailand Hjort , Sven Hastrup
发明人： Fred Hagen , Carsten Mailand Hjort , Sven Hastrup
IPC分类号： C12N1500
CPC分类号： C12Q1/6895 , C11D3/38645 , C12N9/2437 , C12N15/80 , C12Y302/01004 , C12Y302/01039 , C12Y302/01091 , D06M16/003 , D06P5/137 , D06P5/158 , D21H17/005 , D21H21/10
摘要： The present invention relates to cellulase preparations consisting essentially of a homogeneous endoglucanase component. The cellulase preparation may be employed in the treatment of cellulose-containing fabrics for harshness reduction, for color clarification, or to provide a localized variation in the color of such fabrics, or in the treatment of paper pulp.
摘要翻译： 本发明涉及基本上由均匀的内切葡聚糖酶组分组成的纤维素酶制剂。 纤维素酶制剂可用于处理含纤维素的织物以减少粗糙度，进行颜色澄清，或提供这种织物的颜色的局部变化，或纸浆的处理。
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公开(公告)号：US5763254A
公开(公告)日：1998-06-09
申请号：US483432
申请日：1995-06-07
CPC分类号： C12N9/2437 , C12Y302/01004 , C12Y302/01091
摘要： The present invention relates to isolated and purified cellulose- or hemicellulose-degrading enzymes, comprising a catalytically active domain, a carbohydrate binding domain and a linking B region which operably links the catalytically active domain and the carbohydrate binding domain, wherein the carbohydrate binding domain has the following core sequence: ##STR1## wherein the enzyme is endogenous to a strain of a fungus other than Trichoderma or Phanerochaete.
摘要翻译： 本发明涉及分离和纯化的纤维素或半纤维素降解酶，其包含催化活性结构域，碳水化合物结合结构域和可操作地连接催化活性结构域和碳水化合物结合结构域的连接B区，其中碳水化合物结合结构域具有 以下核心序列：
其中所述酶对除木霉属或Phanerochaete之外的真菌菌株是内源的。 -
公开(公告)号：US5457046A
公开(公告)日：1995-10-10
申请号：US361920
申请日：1994-12-22
申请人： Helle F. Woldike , Fred Hagen , Carsten Hjort , Sven Hastrup
发明人： Helle F. Woldike , Fred Hagen , Carsten Hjort , Sven Hastrup
CPC分类号： C12N9/2437 , C12Y302/01004 , C12Y302/01091
摘要： A cellulose- or hemicellulose-degrading enzyme which is derivable from a fungus other than Trichoderma or Phanerochaete, and which comprises a carbohydrate binding domain homologous to a terminal A region of Trichoderma reesei cellulases, which carbohydrate binding domain amino acid sequence (.alpha.) or a subsequence thereof capable of effecting binding of the enzyme to an insoluble cellulosic or hemicellulosic substrate.
摘要翻译： 可衍生自木霉属或Phanerochaete以外的真菌的纤维素或半纤维素降解酶，其包含与里氏木霉纤维素酶的末端A区同源的碳水化合物结合结构域，所述碳水化合物结合结构域氨基酸序列（α）或 其能够影响酶与不溶性纤维素或半纤维素基质的结合。
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公开(公告)号：US20050003986A1
公开(公告)日：2005-01-06
申请号：US10896177
申请日：2004-07-21
申请人： Sven Hastrup , Sven Branner , Fanny Norris , Steffen Petersen , Leif Norskov-Lauridsen , Villy Jensen , Dorrit Aaslyng
发明人： Sven Hastrup , Sven Branner , Fanny Norris , Steffen Petersen , Leif Norskov-Lauridsen , Villy Jensen , Dorrit Aaslyng
IPC分类号： C12N15/09 , C11D3/386 , C11D7/42 , C12N1/21 , C12N9/50 , C12N9/54 , C12N9/56 , C12N15/00 , C12N15/57 , C12P21/02 , C12R1/07 , C12R1/125 , C07H21/04 , C12N15/74 , C12Q1/68
摘要： The present invention relates to mutations of a subtilisin gene which result in changes in the chemical characteristics of subtilisin enzymes. Mutations at specific nucleic acids of the subtilisin gene result in amino acid substitutions and consequently, altered enzyme function. Some of these mutant enzymes exhibit physical properties advantageous to industrial applications, particularly in the detergent industry, providing subtilisin which is more stable to oxidation, possesses greater protease activity, and exhibits improved washability.
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公开(公告)号：US06835821B2
公开(公告)日：2004-12-28
申请号：US10310730
申请日：2002-12-05
申请人： Sven Hastrup , Sven Branner , Fanny Norris , Steffen Bjorn Petersen , Leif Nørskov-Lauridsen , Villy Johannes Jensen , Dorrit Aaslyng
发明人： Sven Hastrup , Sven Branner , Fanny Norris , Steffen Bjorn Petersen , Leif Nørskov-Lauridsen , Villy Johannes Jensen , Dorrit Aaslyng
IPC分类号： C12N1557
摘要： The present invention relates to mutations of a subtilisin gene which result in changes in the chemical characteristics of subtilisin enzymes. Mutations at specific nucleic acids of the subtilisin gene result in amino acid substitutions and consequently, altered enzyme function. Some of these mutant enzymes exhibit physical properties advantageous to industrial applications, particularly in the detergent industry, providing subtilisin which is more stable to oxidation, possesses greater protease activity, and exhibits improved washability.
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公开(公告)号：US06458927B1
公开(公告)日：2002-10-01
申请号：US09048502
申请日：1998-03-26
IPC分类号： C07K100
CPC分类号： C07K14/475 , A01K2217/05 , A61K38/00
摘要： The present invention relates to a polypeptide with appetite regulating function/activity, a nucleic acid construct encoding the polypeptide and a method of producing the polypeptide. The invention further relates to recombinant vectors comprising the nucleic acid construct encoding the polypeptide, recombinant host cells comprising the nucleic acid construct or the recombinant vector.
摘要翻译： 本发明涉及具有食欲调节功能/活性的多肽，编码该多肽的核酸构建体及其制备方法。 本发明还涉及包含编码多肽的核酸构建体的重组载体，包含核酸构建体或重组载体的重组宿主细胞。
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公开(公告)号：US5631217A
公开(公告)日：1997-05-20
申请号：US527734
申请日：1995-09-13
申请人： Sven Branner , Sven Hastrup , Nina Eriksen , Poul Lindegaard , Ole H. Olsen , Eric Casteleijn , Maarten R. Egmond , Johan Haverkamp , Wouter Musters , Jakob de Vlieg
发明人： Sven Branner , Sven Hastrup , Nina Eriksen , Poul Lindegaard , Ole H. Olsen , Eric Casteleijn , Maarten R. Egmond , Johan Haverkamp , Wouter Musters , Jakob de Vlieg
摘要： This invention relates to enzymes, to rDNA techniques applicable for example to their production, to mutated genes, vectors and mutant and transformed microorganisms useful in their production, and to their uses including for example enzymatic detergent and cleaning compositions containing them.
摘要翻译： 本发明涉及酶，适用于例如其生产的rDNA技术，可用于其生产的突变基因，载体和突变和转化的微生物以及其用途，包括例如含有它们的酶洗涤剂和清洁组合物。
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公开(公告)号：US5036002A
公开(公告)日：1991-07-30
申请号：US39298
申请日：1987-04-17
申请人： Sven Hastrup
发明人： Sven Hastrup
CPC分类号： C12N9/54 , C07K14/32 , C12N15/75 , C12N9/6481 , C07K2319/00 , Y10S435/832 , Y10S435/839
摘要： Gene expression systems comprising an expression vector and a "trans-acting DNA segment", where the expression vector comprises the gene or genes to be expressed and one or more cis-acting regulatory elements which are responsive to a trans-acting factor produced by said "trans-acting DNA segment". More specifically the invention relates to such gene expression systems where said "trans-acting DNA segment" and said cis-acting regulatory elements comprise one or more segments of the genome from a Bacillus species. Methods for stimulating the production of gene products, vectors for transforming microorganisms, and their use are also disclosed.
摘要翻译： 包含表达载体和“反式作用DNA片段”的基因表达系统，其中所述表达载体包含要表达的基因或基因，以及一种或多种顺式作用调节元件，其对所述 “反式作用DNA片段”。 更具体地，本发明涉及这样的基因表达系统，其中所述“反式作用DNA片段”和所述顺式作用调节元件包含来自芽孢杆菌属物种的基因组的一个或多个片段。 还公开了刺激基因产物的生成，转化微生物的载体及其用途的方法。
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