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公开(公告)号:US20100150943A1
公开(公告)日:2010-06-17
申请号:US12375042
申请日:2007-07-26
申请人: Guido Grandi , John Telford , Marirosa Mora , Cesira Galeotti , Daniela Rinaudo , Andrea Guido Oreste Manetti
发明人: Guido Grandi , John Telford , Marirosa Mora , Cesira Galeotti , Daniela Rinaudo , Andrea Guido Oreste Manetti
IPC分类号: A61K39/40 , C07K14/195 , A61K39/116 , C12N1/21 , C12P21/00 , A61P31/04
CPC分类号: A61K39/092 , A61K2039/523 , A61K2039/543 , A61K2039/55505 , A61K2039/55566 , C07K14/3156
摘要: The invention relates to the identification of a new adhesin islands within the genomes of several Gram positive Streptococcus serotypes and isolates. Adhesin island polypeptides of the invention may be used in immunogenic compositions for prophylactic or therapeutic immunization against GAS, GBS, and S. pneumococcal infections.
摘要翻译: 本发明涉及在几种革兰氏阳性链球菌血清型和分离物的基因组内鉴定新的粘附素岛。 本发明的粘合素岛多肽可用于针对GAS,GBS和肺炎球菌感染的预防性或治疗性免疫的免疫原性组合物中。
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公开(公告)号:US20120034230A1
公开(公告)日:2012-02-09
申请号:US13144149
申请日:2010-01-12
IPC分类号: A61K39/40 , C07K19/00 , C07K14/31 , C07K17/02 , C12N15/31 , C12N15/63 , C12P21/02 , C07K16/12 , C12N1/21 , C12N1/19 , C12N5/10 , A61K39/09 , A61K39/085 , A61K39/116 , A61P37/04 , A61P31/04 , C07K14/315
CPC分类号: C07K14/315 , A61K39/085 , A61K39/092 , A61K2039/55566 , C07K16/44 , C12N15/03 , C12N15/63
摘要: The invention provides protective antigens which are useful in vaccine compositions to induce protection against gram positive bacteria, particularly against S. agalactiae, S. pyogenes, S. pneumoniae, S. aureus, S. suis, and S. equi.
摘要翻译: 本发明提供了可用于疫苗组合物中的保护性抗原,以诱导针对革兰氏阳性细菌的保护,特别是针对无乳链球菌,化脓性链球菌,肺炎链球菌,金黄色葡萄球菌,猪链球菌和马赛克氏菌。
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公开(公告)号:US08465751B2
公开(公告)日:2013-06-18
申请号:US13144149
申请日:2010-01-12
IPC分类号: A61K39/09 , C12N1/20 , C07K14/315
CPC分类号: C07K14/315 , A61K39/085 , A61K39/092 , A61K2039/55566 , C07K16/44 , C12N15/03 , C12N15/63
摘要: The invention provides protective antigens which are useful in vaccine compositions to induce protection against gram positive bacteria, particularly against S. agalactiae, S. pyogenes, S. pneumoniae, S. aureus, S. suis, and S. equi.
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公开(公告)号:US09102740B2
公开(公告)日:2015-08-11
申请号:US13912472
申请日:2013-06-07
IPC分类号: C12N15/03 , C12P21/04 , C07H21/04 , C07K14/315 , C12N15/63 , A61K39/085 , A61K39/09 , C07K16/44 , A61K39/00
CPC分类号: C07K14/315 , A61K39/085 , A61K39/092 , A61K2039/55566 , C07K16/44 , C12N15/03 , C12N15/63
摘要: The invention provides protective antigens which are useful in vaccine compositions to induce protection against gram positive bacteria, particularly against S. agalactiae, S. pyogenes, S. pneumoniae, S. aureus, S. suis, and S. equi.
摘要翻译: 本发明提供了可用于疫苗组合物中的保护性抗原,以诱导针对革兰氏阳性细菌的保护,特别是针对无乳链球菌,化脓性链球菌,肺炎链球菌,金黄色葡萄球菌,猪链球菌和马赛克氏菌。
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公开(公告)号:US20140017727A1
公开(公告)日:2014-01-16
申请号:US13912472
申请日:2013-06-07
IPC分类号: C07K14/315 , C07K16/44
CPC分类号: C07K14/315 , A61K39/085 , A61K39/092 , A61K2039/55566 , C07K16/44 , C12N15/03 , C12N15/63
摘要: The invention provides protective antigens which are useful in vaccine compositions to induce protection against gram positive bacteria, particularly against S. agalactiae, S. pyogenes, S. pneumoniae, S. aureus, S. suis, and S. equi.
摘要翻译: 本发明提供了可用于疫苗组合物中的保护性抗原,以诱导针对革兰氏阳性细菌的保护,特别是针对无乳链球菌,化脓性链球菌,肺炎链球菌,金黄色葡萄球菌,猪链球菌和马赛克氏菌。
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