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公开(公告)号：US20200009558A1
公开(公告)日：2020-01-09
申请号：US16493402
申请日：2017-04-07
摘要： The present disclosure is drawn to microfluidic devices. In one example, a microfluidic device can include a first covered fluid feed slot in fluid communication with a first microfluidic channel and a second covered fluid feed slot in fluid communication with a second microfluidic channel. The first microfluidic channel can be formed adjacent to the second microfluidic channel but not in fluid communication with the second microfluidic channel. The first covered fluid feed slot can include a first fluid feed hole for filling a fluid into the first covered fluid feed slot. The second covered fluid feed slot can also include a second fluid feed hole for filling a fluid into the second covered fluid feed slot.
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公开(公告)号：US20200206734A1
公开(公告)日：2020-07-02
申请号：US16643264
申请日：2017-11-22
发明人： Hilary ELY , Adam HIGGINS , Rachel M. WHITE , Erik D. TORNIAINEN , Tod WOODFORD , Michael W. CUMBIE , Chien-Hua CHEN
IPC分类号： B01L3/00
摘要： The present disclosure is drawn to microfluidic devices. A microfluidic device can include a substrate, a lid mounted to the substrate, and a microchip mounted to the substrate. The lid mounted to the substrate can form a discrete microfluidic chamber between structures including an interior surface of the lid and a portion of the substrate. The lid can include an inlet and a vent positioned relative to one another to facilitate loading of fluid to the discrete microfluidic chamber via capillary action. A portion of the microchip can be positioned within the discrete microfluidic chamber.
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公开(公告)号：US20210011045A1
公开(公告)日：2021-01-14
申请号：US16603476
申请日：2017-09-15
IPC分类号： G01N35/10 , B01L3/02 , C12Q1/6844
摘要： Examples disclosed herein relate to a device. Examples include a region selection engine to determine a plurality of regions on a well plate, a number of wells in each region, and a location of each well in each region; and a dispense engine to determine a quantity of DNA concentrate to dispense in each well of the plurality of regions on the well plate, and the dispense engine to control a fluid dispensing device to eject the quantity of DNA concentrate into each well of each region of the well plate. In examples, a quantity of DNA fragments in the DNA concentrate is unknown.
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公开(公告)号：US20200332342A1
公开(公告)日：2020-10-22
申请号：US16643054
申请日：2017-10-20
IPC分类号： C12Q1/686 , C12Q1/6806 , B01L7/00 , B01L3/00
摘要： A nucleic acid amplifier may include a sample preparation zone, a fluid ejector, an amplification zone and a capillary break between the amplification zone and the fluid ejector.
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公开(公告)号：US20210060548A1
公开(公告)日：2021-03-04
申请号：US16643954
申请日：2017-11-22
摘要： The present disclosure is drawn to temperature-cycling microfluidic devices. In one example, a temperature-cycling microfluidic device can include a driver chip having a top surface and a heat exchange substrate having a top surface coplanar with the top surface of the driver chip. A fluid chamber can be located on the top surface of the driver chip. A first and second microfluidic loop can have fluid driving ends and fluid outlet ends connected to the fluid chamber and can include portions thereof located on the top surface of the heat exchange substrate. A first and second fluid actuator can be on the driver chip. The first and second fluid actuators can be associated with the fluid driving ends of the first and second microfluidic loops, respectively, to circulate fluid through the first and second microfluidic loops.
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公开(公告)号：US20210008547A1
公开(公告)日：2021-01-14
申请号：US16603460
申请日：2017-09-15
IPC分类号： B01L3/00 , G01N35/10 , C12Q1/6844
摘要： Examples disclosed herein relate to a device. Examples include a region selection engine to determine a plurality of regions on a well plate, a number of wells in each region, and a location of each well in each region; and a dispense engine to determine a quantity of DNA concentrate under 1 microliter to dispense in each well of the plurality of regions on the well plate, and the dispense engine to control a fluid dispensing device to eject the quantity of DNA concentrate into each well of each region of the well plate. In examples, a quantity of DNA fragments in the DNA concentrate is unknown.
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公开(公告)号：US20200368750A1
公开(公告)日：2020-11-26
申请号：US16768881
申请日：2018-10-03
摘要： A fluid thermal processing device may include a substrate, a platform projecting from the substrate, a fluid heating element supported by the platform, a temperature sensing element, distinct from the fluid heating element, supported by the platform and an enclosure supported by and cooperating with the substrate to form a fluid chamber about the platform. The fluid chamber forms a volume of uniform thickness conforming to and about the platform.
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