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    ELECTRODE SYSTEM
    1.
    发明申请
    ELECTRODE SYSTEM 审中-公开

    公开(公告)号：US20180224384A1

    公开(公告)日：2018-08-09

    申请号：US15749319

    申请日：2016-01-29

    Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

    Inventor： Tod WOODFORD ,  Hilary ELY ,  Sadiq BENGALI

    IPC: G01N27/02

    CPC classification number: G01N27/02

    Abstract: An electrode system and a method of using an electrode system to make an impedance measurement. The electrode system comprises a substrate that supports a first and second electrodes. The first electrode is located inside a cutout of the second electrode. The first and second electrodes are separated by an insulating layer.

    DNA CONCENTRATE DISPENSING
    3.
    发明申请
    DNA CONCENTRATE DISPENSING 有权

    公开(公告)号：US20210008547A1

    公开(公告)日：2021-01-14

    申请号：US16603460

    申请日：2017-09-15

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Hilary ELY ,  Adam HIGGINS ,  Christie DUDENHOEFER ,  Jeffrey A. NIELSEN

    IPC: B01L3/00 ,  G01N35/10 ,  C12Q1/6844

    Abstract: Examples disclosed herein relate to a device. Examples include a region selection engine to determine a plurality of regions on a well plate, a number of wells in each region, and a location of each well in each region; and a dispense engine to determine a quantity of DNA concentrate under 1 microliter to dispense in each well of the plurality of regions on the well plate, and the dispense engine to control a fluid dispensing device to eject the quantity of DNA concentrate into each well of each region of the well plate. In examples, a quantity of DNA fragments in the DNA concentrate is unknown.

    CONCENTRATING BIOLOGICAL COMPONENTS
    5.
    发明申请
    CONCENTRATING BIOLOGICAL COMPONENTS 有权

    公开(公告)号：US20220251539A1

    公开(公告)日：2022-08-11

    申请号：US17630613

    申请日：2019-10-29

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Si-Lam J. CHOY ,  Hilary ELY ,  John LAHMANN ,  Uranbileg DAALKHAIJAV ,  Sarah GISH

    IPC: C12N15/10 ,  B01L3/00 ,  G01N1/40

    Abstract: A biological component concentration fluid assembly includes magnetizing microparticles that are surface-activated to bind with (or are bound to) a biological component; a multi-fluid density gradient column with a first fluid layer, a second fluid layer, and a third fluid layer; and a magnet to attract and draw the magnetizing microparticles from the first fluid layer, through the second fluid layer, and into the third fluid layer. The first fluid layer has a first fluid density, and a second fluid layer has a second fluid density that is greater than the first fluid density, and is positioned beneath the first fluid layer. A third fluid layer has a third fluid density that is greater than the second fluid density and is positioned beneath the second fluid layer. The second and third fluid layers in this example are formulated to interact with the surface of the magnetizing microparticles.

    FLUID PREPARATION DEVICES
    8.
    发明申请
    FLUID PREPARATION DEVICES 有权

    公开(公告)号：US20220297115A1

    公开(公告)日：2022-09-22

    申请号：US17642279

    申请日：2020-05-08

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Si-Lam J. CHOY ,  Hilary ELY

    IPC: B01L3/00 ,  C12N15/10

    Abstract: A fluid preparation device can include a fluid-receiving vessel and a fluid loader with multiple fluid chambers including a first fluid chamber and a second fluid chamber. The multiple fluid chambers can partially be defined by actuator seals that are positioned on an actuator. The actuator can be moveable among a plurality of positions and the actuator seals can be positioned on the actuator to fluidically separate the first fluid chamber from the second fluid chamber when the actuator is in a closed position from the plurality of positions, allow fluidic communication between the second fluid chamber and the fluid-receiving vessel when the actuator is in a first open position from the plurality of positions, and allow fluidic communication between the first fluid chamber and the second fluid chamber when the actuator is in a second open position from the plurality of positions.

    MULTI-FLUID DENSITY GRADIENT COLUMNS
    9.
    发明申请
    MULTI-FLUID DENSITY GRADIENT COLUMNS 有权

    公开(公告)号：US20220250061A1

    公开(公告)日：2022-08-11

    申请号：US17630592

    申请日：2019-10-29

    Applicant: Hewlett-Packard Development Company, L.P.

    Inventor： Si-Lam J. Choy ,  Hilary ELY

    IPC: B01L3/00 ,  B03C1/01 ,  B03C1/28

    Abstract: The present disclosure includes a method of forming and loading a multi-fluid density gradient column. The method can include forming a multi-fluid density gradient column and loading magnetizing microparticles into a first fluid layer or a second fluid layer of the multi-fluid density gradient column. Forming the multi-fluid density gradient column can include loading a first fluid having a first fluid density in a multi-fluid density gradient column to form a first fluid layer and loading a second fluid having a second fluid density greater than the first fluid density in the multi-fluid density gradient column to form a second fluid layer. The multi-fluid density gradient column can be fluidly coupled to a fluid processing device. The magnetizing microparticles can be surface-activated to bind with a biological component or can be bound to the biological component.

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