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公开(公告)号：US11759793B2
公开(公告)日：2023-09-19
申请号：US17983479
申请日：2022-11-09
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , Daixi Xin
CPC classification number: B03C5/026 , B01D17/06 , B03C5/028 , B25J9/0087 , B25J9/06 , B25J9/1666
Abstract: An object separator may include a substrate, a fluid channel supported by the substrate, a pair of electrodes along the fluid channel to form a dielectrophoretic force to interact with an object entrained in a fluid, and an inertial pump supported by the substrate and positioned within the fluid channel to move the fluid along the fluid channel.
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公开(公告)号：US20210009931A1
公开(公告)日：2021-01-14
申请号：US16606841
申请日：2018-04-04
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Viktor Shkolnikov , Daixi Xin
Abstract: The present disclosure is drawn to microfluidic cellular membrane modification devices. In one example, a microfluidic cellular membrane modification device can include a microfluidic channel including a pumping portion and an electric field portion. An electrode pair can be positioned about the electric field portion. A bidirectional pump can be in fluid communication with the microfluidic channel at the pumping portion to move fluid backward and forward through the electric field portion.
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公开(公告)号：US20210213449A1
公开(公告)日：2021-07-15
申请号：US17054499
申请日：2018-09-26
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , Daixi Xin , Chien-Hua Chen
Abstract: In example implementations, an apparatus is provided. The apparatus includes a microfluidic channel to receive a fluid containing a plurality of different cells. A dielectrophoresis (DEP) separator in the apparatus separates the plurality of different cells passing through DEP separator within the microfluidic channel. In addition, the apparatus includes a density separator to further separate a portion of the plurality of different cells from the DEP separator based on a density of each one of the plurality of different cells.
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公开(公告)号：US20210205812A1
公开(公告)日：2021-07-08
申请号：US17255789
申请日：2018-09-24
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , Caitlin DeJong , Daixi Xin
IPC: B01L3/00 , B03C5/00 , B03C5/02 , G01N27/447
Abstract: Techniques for separating particles of interest from whole blood are disclosed. An example particle separation chip includes a first inlet on the particle separation chip for receiving whole blood and a second inlet on the particle separation chip for receiving a lysis buffer. The particle separation chip also includes a mixer to mix the whole blood with the lysis buffer to provide lysis of red blood cells in the whole blood. The particle separation chip also includes a buffer exchanger to exchange the lysis buffer for a dielectrophoresis buffer to produce a solution that enables dielectrophoretic separation of particles of interest. The particle separation chip also includes a separator coupled to an output of the buffer exchanger to separate the particles of interest from other particles in the solution via dielectrophoretic separation and deliver the particles of interest to an outlet on the particle separation chip.
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公开(公告)号：US20240201130A1
公开(公告)日：2024-06-20
申请号：US18590723
申请日：2024-02-28
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , Yang Lei , Daixi Xin
IPC: G01N27/447 , B03C5/00 , B03C5/02
CPC classification number: G01N27/44713 , B03C5/005 , B03C5/026 , B03C2201/26
Abstract: In example implementations, an apparatus is provided. The apparatus includes a dielectrophoresis (DEP) separator, an electrical field generator, a tracking system, and a controller. The DEP separator is to separate a plurality of different particles. The electrical field generator is coupled to the DEP separator to apply a frequency to the DEP separator. The tracking system is to track a movement of a type of particles in the DEP separator. The controller is in communication with the electrical field generator to control the frequency and the tracking system to track the separation. The controller is to calculate a cross-over frequency from a cross-over frequency distribution for the type of particles based on a frequency sweep performed on the type of particles and the movement of the type of particles that is tracked.
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Patent Agency Ranking
公开(公告)号：US11946902B2
公开(公告)日：2024-04-02
申请号：US17056488
申请日：2018-10-11
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , Yang Lei , Daixi Xin
IPC: G01N27/447 , B03C5/00 , B03C5/02
CPC classification number: G01N27/44713 , B03C5/005 , B03C5/026 , B03C2201/26
Abstract: In example implementations, an apparatus is provided. The apparatus includes a dielectrophoresis (DEP) separator, an electrical field generator, a tracking system, and a controller. The DEP separator is to separate a plurality of different particles. The electrical field generator is coupled to the DEP separator to apply a frequency to the DEP separator. The tracking system is to track a movement of a type of particles in the DEP separator. The controller is in communication with the electrical field generator to control the frequency and the tracking system to track the separation. The controller is to calculate a cross-over frequency from a cross-over frequency distribution for the type of particles based on a frequency sweep performed on the type of particles and the movement of the type of particles that is tracked.
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公开(公告)号：US11927520B2
公开(公告)日：2024-03-12
申请号：US17415130
申请日：2019-05-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , Daixi Xin , Yang Lei
CPC classification number: G01N15/1031 , G01N15/0227 , G01N2015/0053
Abstract: A particle monitoring system may include a flow passage, a particle imager to image a targeted particle within the flow passage, electrodes supported proximate the flow passage, a power source connected to the electrodes and a controller to cause the power source to charge to electrodes so as to (1) apply an electric field balanced with respect to gravity so as to hold, levitate and rotate a targeted particle within the flow passage during imaging and (2) release the targeted particle following the imaging.
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公开(公告)号：US20230237734A1
公开(公告)日：2023-07-27
申请号：US18007736
申请日：2020-06-05
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Yang Lei , Viktor Shkolnikov , Daixi Xin
IPC: G06T17/00
CPC classification number: G06T17/00 , G06T2210/41
Abstract: A three-dimensional (3D) biological cell constituent concentration reconstruction method may include capturing two-dimensional images of a biological cell at different angles, virtually partitioning the biological cell into a 3D stacks of voxels, assigning cell constituent concentration estimations to respective voxels based upon a plurality of the two-dimensional images and forming a 3D cell constituent concentration model of the biological cell based upon the voxels and respective cell constituent concentration estimations.
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公开(公告)号：US20210223203A1
公开(公告)日：2021-07-22
申请号：US17056488
申请日：2018-10-11
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , Yang Lei , Daixi Xin
IPC: G01N27/447 , B03C5/00 , B03C5/02
Abstract: In example implementations, an apparatus is provided. The apparatus includes a dielectrophoresis (DEP) separator, an electrical field generator, a tracking system, and a controller. The DEP separator is to separate a plurality of different particles. The electrical field generator is coupled to the DEP separator to apply a frequency to the DEP separator. The tracking system is to track a movement of a type of particles in the DEP separator. The controller is in communication with the electrical field generator to control the frequency and the tracking system to track the separation. The controller is to calculate a cross-over frequency from a cross-over frequency distribution for the type of particles based on a frequency sweep performed on the type of particles and the movement of the type of particles that is tracked.
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公开(公告)号：US12204085B2
公开(公告)日：2025-01-21
申请号：US16606239
申请日：2018-04-27
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Viktor Shkolnikov , Daixi Xin , Yang Lei
IPC: G02B21/36 , G01N33/483 , G06T17/00 , H04N23/66
Abstract: A three-dimensional object modeling method may include applying a nonrotating nonuniform electric field to apply a dielectrophoretic torque to a three-dimensional object to rotate the three-dimensional object, capturing images of the object at different angles during rotation of the object and forming a three-dimensional model of the object based on the captured images.
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