公开(公告)号：US20190193076A1

公开(公告)日：2019-06-27

申请号：US16098976

申请日：2016-07-14

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Christie DUDENHOEFER ,  Jeffrey A. NIELSEN ,  Kenneth WARD ,  Matthew David SMITH ,  Hilary ELY

IPC: B01L3/00

CPC classification number: B01L3/502715 ,  B01L3/5085 ,  B01L3/50853 ,  B01L2200/025 ,  B01L2200/0689 ,  B01L2300/0627

Abstract: A microplate lid is disclosed. An electronics board includes a plurality of board throughholes corresponding to well locations of a microplate. A cover plate includes a plurality of plate throughholes corresponding to respective board throughholes to define a plurality of plate-board throughhole pairs. The cover plate is located atop the electronics board. A plurality of directing lumens is at least partially defined by the cover plate. Each directing lumen corresponds to a respective plate throughhole. A plurality of user-perceptible array indicators is provided to the electronics board. Each array indicator is associated with a different plate-board throughhole pair than every other array indicator.

公开(公告)号：US20220322538A1

公开(公告)日：2022-10-06

申请号：US17608078

申请日：2019-07-01

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Vignesh KANNAN ,  Dennis R. ESTERBERG ,  Christie DUDENHOEFER ,  Kenneth WARD ,  Matthew David SMITH ,  Daniel FRADL

IPC: H05K3/30

Abstract: In one example in accordance with the present disclosure, a fluid ejection controller is described. The fluid ejection controller includes a firing board to pass control signals to a fluid ejection device to eject fluid from the fluid ejection device. A mount pivotally holds the firing board between a disengaged position where electrical pins of the firing board are not in contact with electrical pads of the fluid ejection device and an engaged position where the electrical pins are in contact with the electrical pads. The mount includes a slot to receive the fluid ejection device and at least one biasing spring to bias the firing board away from the fluid ejection device during insertion of the fluid ejection device. The fluid ejection controller also includes a handle coupled to a cam shaft to move the firing board between the disengaged position and the engaged position.

公开(公告)号：US20190168207A1

公开(公告)日：2019-06-06

申请号：US16099460

申请日：2016-07-14

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Matthew David SMITH ,  Christie DUDENHOEFER ,  Jeffrey A. NIELSEN ,  Kenneth WARD ,  Hilary ELY

IPC: B01L3/02

Abstract: An apparatus includes a pipette dispenser to control dispensing of a volume to a dispensing location. A tip is operatively coupled to the pipette dispenser. The tip includes an electromechanical print head to dispense the volume from the pipette dispenser to the dispensing location based on a command from the pipette dispenser that indicates an amount of the volume to be dispensed from the print head.

公开(公告)号：US20190151849A1

公开(公告)日：2019-05-23

申请号：US16099668

申请日：2016-07-26

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Jeffrey A NIELSEN ,  Manish GIRI ,  Chantelle DOMINGUE ,  Kenneth WARD ,  Christie DUDENHOEFER ,  Matthew David SMITH ,  Joshua M. YU ,  Diane R. HAMMERSTAD ,  Hilary ELY

IPC: B01L3/00 ,  B01L3/02

Abstract: According to an example, a microfluidic apparatus may include a channel, a foyer, in which the foyer is in fluid communication with the channel and in which the channel has a smaller width than the foyer, a sensor to sense a property of a fluid passing through the channel, a nozzle in fluid communication with the foyer, and an actuator positioned in line with the nozzle. The microfluidic apparatus may also include a controller to determine whether the sensed property of the fluid meets a predetermined condition and to perform a predefined action in response to the sensed property of the fluid meeting the predetermined condition.

公开(公告)号：US20190076837A1

公开(公告)日：2019-03-14

申请号：US16085253

申请日：2016-03-31

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Jeffrey A. NIELSEN ,  Michael W. CUMBIE ,  Devin Alexander MOUREY ,  Silam J. CHOY ,  Kenneth WARD ,  Christie DUDENHOEFER

IPC: B01L3/02

Abstract: A digital dispense apparatus includes at least one fluid dispense device, at least one reservoir fluidically connected to the at least one fluid dispense device, a monolithic carrier structure carrying the at least one fluid dispense device and reservoir, the monolithic carrier forming fluid routing between the reservoir and the fluid dispense device.

公开(公告)号：US20220184601A1

公开(公告)日：2022-06-16

申请号：US17603412

申请日：2019-10-10

Applicant: Hewlett-Packard Development Company, L.P.

Inventor： Erica Midttveit SQUIRES ,  Roberto A. PUGLIESE ,  Kenneth WARD ,  Kathryn H. CYR

IPC: B01L3/02

Abstract: A microfluidic dispenser can include a processor to receive a user input via a user interface related to limiting dilution (or a limiting dilution assay) to be performed, and calculate a dispense volume of a fluid for the limiting dilution based on the user input. The microfluidic dispenser can also include a dispense cassette including a fluid reservoir, and a microfluidic dispense head to dispense the fluid via a nozzle in accordance with the calculated dispense volume.

公开(公告)号：US20210179991A1

公开(公告)日：2021-06-17

申请号：US16076545

申请日：2017-06-09

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Viktor SHKOLNIKOV ,  Kenneth WARD

IPC: C12M3/06 ,  B01L3/02 ,  C12M1/00 ,  C12M1/42 ,  C12N15/87

Abstract: A microfluidic device may include a microfluidic channel including an electrode placed at opposite ends of the microfluidic channel to create an electrical field within the channel and an ejection device to eject at least one cell porated within the electrical field. A cassette may include a substrate, a die coupled to the substrate, a microfluidic channel defined within the die, the microfluidic channel including a necked portion to receive a cell therein and at least two electrodes each placed at a first and a second end of the microfluidic channel to apply an electric field to the cell above a proration threshold and a cell ejection device to eject the cell from the die.

公开(公告)号：US20210060543A1

公开(公告)日：2021-03-04

申请号：US16605945

申请日：2017-09-27

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： David OCHS ,  Kenneth WARD

IPC: B01L3/02

Abstract: Examples disclosed herein relate to a device. Examples to determine a dispense routine for a default dilution of a compound according to a dispense request identifying a second dilution of the compound, and a dispense engine to control the dispense device to dispense at least a portion of the default dilution of the compound according to the dispense routine. In examples, the dilution engine is to determine the dispense routine by comparing the second dilution to the default dilution to determine whether the default dilution is dilutable to the second dilution.

公开(公告)号：US20180321155A1

公开(公告)日：2018-11-08

申请号：US15764880

申请日：2016-01-29

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Charles M. SANTORI ,  James William STASIAK ,  Francesco AIETA ,  Anita ROGACS ,  Mineo YAMAKAWA ,  Kenneth WARD

IPC: G01N21/65

CPC classification number: G01N21/658 ,  G01N2201/0635

Abstract: Optical readers are disclosed in examples herein. An example optical reader including a light source to emit a light beam; and a spot pattern generator to receive the light beam and to generate a two-dimensional spot array from the light beam, the two-dimensional spot array to be directed toward a substrate having nanostructures, the two-dimensional spot array to be sensed to detect a presence or an absence of a substance of interest on the substrate.

公开(公告)号：US20220297113A1

公开(公告)日：2022-09-22

申请号：US17836005

申请日：2022-06-09

Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.

Inventor： Jeffrey A. NIELSEN ,  Michael W. CUMBIE ,  Devin Alexander MOUREY ,  Silam J. CHOY ,  Kenneth WARD ,  Christie DUDENHOEFER

IPC: B01L3/02

Abstract: A method of manufacturing a digital dispense apparatus includes molding a monolithic carrier structure, forming cut outs into a planar top surface of the monolithic carrier structure, the cut outs including a reservoir extending into part of a thickness of the monolithic carrier structure and fluid routing to connect the reservoir with a fluid dispense device, and overmolding the fluid dispense device into the monolithic carrier structure on a side of the monolithic carrier structure that is opposite to the reservoir to fluidically connect to the fluid routing.