公开(公告)号：US10246675B2

公开(公告)日：2019-04-02

申请号：US14762301

申请日：2014-01-27

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Ryusuke Kimura ,  Hiromi Yamashita ,  Motohiro Yamazaki ,  Taro Nakazawa

IPC: C12M3/00 ,  F16K31/126 ,  F16K7/17 ,  G01N35/08 ,  B01L3/00 ,  C12M1/40 ,  C12M1/107

Abstract: A cartridge sealed from ambient air is used to send a liquid without causing the liquid to contact the fluid inside the cartridge. Inside of the cartridge 1 sealed from ambient air are provided chambers that send and receive reagents, and an elastic body membrane 51 is attached to the bottom surface. The cartridge main body 51 does not have a groove or anything else that becomes a channel, and the membrane 51 is not bonded to portions that become channels. A channel, not formed in a normal state, is formed upon deforming the membrane 51 under air pressure in the unbonded portion, and the fluid is moved inside. A valve function is provided at an inlet of each chamber, and the fluid is internally moved in any direction with channel deformation.

公开(公告)号：US20150151295A1

公开(公告)日：2015-06-04

申请号：US14416084

申请日：2013-06-18

Applicant: Hitachi High-Technologies Corporation

Inventor： Ryusuke Kimura ,  Hiromi Yamashita ,  Motohiro Yamazaki

IPC: B01L3/00

CPC classification number: B01L3/50273 ,  B01L3/502715 ,  B01L3/502723 ,  B01L3/502738 ,  B01L2200/0605 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/123 ,  B01L2400/0481 ,  B01L2400/0655

Abstract: A cartridge sealed from an external air is used to enable mixing with a reagent, agitating, purification, reaction, etc. Provided inside the cartridge 1 sealed from the external air are a chamber 38 for the reagent to be transported, a chamber 39 to which the reagent is transported, and the chambers are connected by a liquid transport channel. A groove is made in a cartridge body 30 and a membrane 31 as an elastic body is pasted onto the groove to form the liquid transport channel 36. Air pressure is given to the membrane 31 to change the volume of the liquid transport channel 31 and thereby move the fluid inside. The inlet of each chamber has a valve function to move the fluid inside in a desired direction according to change of the liquid transport channel. This enables transportation of the liquid inside the cartridge sealed from the external air so that mixing with the reagent, agitating, purification, reaction, etc. can be performed in the cartridge. In addition, a valve structure is provided not in the cartridge but in a holder 2 on which the cartridge is loaded, so the cost of the cartridge can be reduced.

Abstract translation: 使用与外部空气密封的筒，以使其能够与试剂混合，搅拌，净化，反应等。在从外部空气密封的盒1内设置有用于待运送试剂的室38，室39， 试剂被输送，并且室通过液体输送通道连接。 在盒主体30中形成凹槽，将作为弹性体的膜31粘贴到凹槽上以形成液体输送通道36.空气压力被施加到膜31以改变液体输送通道31的体积，从而 移动流体内。 每个室的入口具有阀功能，以根据液体输送通道的变化在所需方向内移动流体。 这使得能够将盒内的液体从外部空气密封，使得可以在盒中进行与试剂的混合，搅拌，净化，反应等。 此外，阀结构不设置在盒中，而是设置在其上装载盒的保持器2中，因此可以降低盒的成本。

公开(公告)号：US09415391B2

公开(公告)日：2016-08-16

申请号：US14416084

申请日：2013-06-18

Applicant: Hitachi High-Technologies Corporation

Inventor： Ryusuke Kimura ,  Hiromi Yamashita ,  Motohiro Yamazaki

IPC: B01L3/00

CPC classification number: B01L3/50273 ,  B01L3/502715 ,  B01L3/502723 ,  B01L3/502738 ,  B01L2200/0605 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/0874 ,  B01L2300/123 ,  B01L2400/0481 ,  B01L2400/0655

Abstract: A cartridge sealed from an external air is used to enable mixing with a reagent, agitating, purification, reaction, etc. Provided inside the cartridge sealed from the external air are a chamber for the reagent to be transported, a chamber to which the reagent is transported, and the chambers are connected by a liquid transport channel. A groove is made in a cartridge body and a membrane as an elastic body is pasted onto the groove to form the liquid transport channel. Air pressure is given to the membrane to change the volume of the liquid transport channel and thereby move the fluid inside. The inlet of each chamber has a valve function to move the fluid inside in a desired direction according to change of the liquid transport channel. This enables transportation of the liquid inside the cartridge sealed from the external air.

Abstract translation: 使用与外部空气密封的盒，以使其能够与试剂混合，搅拌，净化，反应等。在从外部空气密封的盒中设置有用于待运送试剂的室，试剂为 运输，并且室通过液体输送通道连接。 在盒体中形成凹槽，将作为弹性体的膜粘贴到凹槽上以形成液体输送通道。 给予膜的空气压力以改变液体输送通道的体积，从而使流体在内部移动。 每个室的入口具有阀功能，以根据液体输送通道的变化在所需方向内移动流体。 这使得能够将盒内的液体从外部空气密封。