公开(公告)号：US10884008B2

公开(公告)日：2021-01-05

申请号：US15309550

申请日：2015-04-27

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Taro Nakazawa ,  Motohiro Yamazaki ,  Tatsuya Yamashita ,  Yoshitaka Kodama

IPC: B01L3/00 ,  G01N35/10 ,  B01L7/00 ,  G01N35/00

Abstract: Provided are: a device for storing biochemical reagents wherein an amount of a reagent can be hermetically stored and dropped from a storage site without coming into contact with the outside air; and a biochemical analyzer using the device. The device (10) is constituted by: sticking a top sheet (32) to a base sheet (31) provided with a convex-shaped hollow pocket (16) in which a reagent can be housed; a reagent container as a PTP packaging sheet (30) wherein an opening of the pocket in the base sheet (31), in which a reagent is preliminarily housed, is hermetically sealed with the top sheet (32); and sticking the film sheet surface as the top sheet (32) of the PTP packaging sheet (30), in which the reagent is hermetically packaged, to a cartridge surface of a device body (20) to thereby hermetically seal the inside of the device body too.

公开(公告)号：US20170138974A1

公开(公告)日：2017-05-18

申请号：US15309550

申请日：2015-04-27

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Taro Nakazawa ,  Motohiro Yamazaki ,  Tatsuya Yamashita ,  Yoshitaka Kodama

IPC: G01N35/10

CPC classification number: G01N35/1002 ,  B01L3/502715 ,  B01L3/523 ,  B01L7/52 ,  B01L2200/027 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/0887 ,  B01L2300/1822 ,  B01L2400/0481 ,  B01L2400/0633 ,  B01L2400/0683 ,  G01N2035/00158 ,  G01N2035/1041

Abstract: Provided are: a device for storing biochemical reagents wherein an amount of a reagent can be hermetically stored and dropped from a storage site without coming into contact with the outside air; and a biochemical analyzer using the device. The device (10) is constituted by: sticking a top sheet (32) to a base sheet (31) provided with a convex-shaped hollow pocket (16) in which a reagent can be housed; a reagent container as a PTP packaging sheet (30) wherein an opening of the pocket in the base sheet (31), in which a reagent is preliminarily housed, is hermetically sealed with the top sheet (32); and sticking the film sheet surface as the top sheet (32) of the PTP packaging sheet (30), in which the reagent is hermetically packaged, to a cartridge surface of a device body (20) to thereby hermetically seal the inside of the device body too.

公开(公告)号：US11426721B2

公开(公告)日：2022-08-30

申请号：US16313485

申请日：2017-06-26

Applicant: Hitachi High-Technologies Corporation

Inventor： Yoshihiro Nagaoka ,  Taro Nakazawa ,  Mitsuhiro Miyazaki ,  Ryusuke Kimura ,  Motohiro Yamazaki

IPC: G01N35/08 ,  G01N21/05 ,  B01L3/00 ,  G01N37/00 ,  C12M1/00

Abstract: Provided are a bubble eliminating structure and a bubble eliminating method which eliminate bubbles in a liquid by agitating the liquid, and an agitating method using the same. A first groove 114, which is an upstream bubble eliminating groove, and a second groove 131, which is a downstream bubble eliminating groove, are branched from a mixing well 13. After starting suction of the liquid from mixing well 13 into the first groove 114, suction of the liquid from the mixing well 13 into the second groove 131 is started, and after completion of discharge of the liquid from the first groove 114 into the mixing well 13, discharge of the liquid from the second groove 131 into the mixing well 13 is completed. This operation is repeated to eliminate bubbles.

公开(公告)号：US10246675B2

公开(公告)日：2019-04-02

申请号：US14762301

申请日：2014-01-27

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Ryusuke Kimura ,  Hiromi Yamashita ,  Motohiro Yamazaki ,  Taro Nakazawa

IPC: C12M3/00 ,  F16K31/126 ,  F16K7/17 ,  G01N35/08 ,  B01L3/00 ,  C12M1/40 ,  C12M1/107

Abstract: A cartridge sealed from ambient air is used to send a liquid without causing the liquid to contact the fluid inside the cartridge. Inside of the cartridge 1 sealed from ambient air are provided chambers that send and receive reagents, and an elastic body membrane 51 is attached to the bottom surface. The cartridge main body 51 does not have a groove or anything else that becomes a channel, and the membrane 51 is not bonded to portions that become channels. A channel, not formed in a normal state, is formed upon deforming the membrane 51 under air pressure in the unbonded portion, and the fluid is moved inside. A valve function is provided at an inlet of each chamber, and the fluid is internally moved in any direction with channel deformation.