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1.发明授权公开(公告)号：US11426721B2
公开(公告)日：2022-08-30
申请号：US16313485
申请日：2017-06-26
摘要： Provided are a bubble eliminating structure and a bubble eliminating method which eliminate bubbles in a liquid by agitating the liquid, and an agitating method using the same. A first groove 114, which is an upstream bubble eliminating groove, and a second groove 131, which is a downstream bubble eliminating groove, are branched from a mixing well 13. After starting suction of the liquid from mixing well 13 into the first groove 114, suction of the liquid from the mixing well 13 into the second groove 131 is started, and after completion of discharge of the liquid from the first groove 114 into the mixing well 13, discharge of the liquid from the second groove 131 into the mixing well 13 is completed. This operation is repeated to eliminate bubbles.
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公开(公告)号：US10451553B2
公开(公告)日：2019-10-22
申请号：US15129287
申请日：2015-03-18
IPC分类号： G01N21/64 , G01J3/44 , G01N27/447 , G01J3/02
摘要： During analysis of samples of unknown concentration, situations frequently occur in which the dynamic range is insufficient, necessitating reanalysis. Accordingly, a fluorescence spectrometer which splits a single object image into multiple images having different fluorescent intensity by means of image splitting elements, and simultaneously detects the plurality of images obtained thereby in different regions within the same detection plane, is proposed.
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公开(公告)号：US10246675B2
公开(公告)日：2019-04-02
申请号：US14762301
申请日：2014-01-27
摘要： A cartridge sealed from ambient air is used to send a liquid without causing the liquid to contact the fluid inside the cartridge. Inside of the cartridge 1 sealed from ambient air are provided chambers that send and receive reagents, and an elastic body membrane 51 is attached to the bottom surface. The cartridge main body 51 does not have a groove or anything else that becomes a channel, and the membrane 51 is not bonded to portions that become channels. A channel, not formed in a normal state, is formed upon deforming the membrane 51 under air pressure in the unbonded portion, and the fluid is moved inside. A valve function is provided at an inlet of each chamber, and the fluid is internally moved in any direction with channel deformation.
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公开(公告)号：US09492821B2
公开(公告)日：2016-11-15
申请号：US14770978
申请日：2014-01-30
CPC分类号： B01L3/502715 , B01F13/0083 , B01J19/00 , B01L3/502738 , B01L2200/0621 , B01L2300/0867 , B01L2300/0877 , B01L2400/0633
摘要： In some examples, a liquid feeding device includes a main flow passage in which a fluid may be fed between an upstream side and a downstream side. A first flow passage may branch from the main flow passage, and may include a narrow flow passage at a terminal end portion, having a smaller cross-sectional area than the first flow passage. A liquid feeding mechanism may feed the fluid to the main flow passage and the first flow passage. The narrow flow passage may suppress the fluid from leaking from first flow passage. Thus, the liquid feeding device may quantitatively determine a first volume of the fluid by filling the first flow passage with the fluid, and subsequently feeding the quantitatively determined fluid back to the main flow passage.
摘要翻译： 在一些示例中，液体供给装置包括主流路，流体可以在上游侧和下游侧供给。 第一流路可以从主流路分支，并且在末端部可以包括具有比第一流路更小的横截面面积的窄流路。 液体供给机构可以将流体供给到主流路和第一流路。 狭窄的流动通道可以抑制流体从第一流动通道泄漏。 因此，液体供给装置可以通过用流体填充第一流路来定量地确定第一体积的流体，并且随后将定量确定的流体送回到主流动通道。
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公开(公告)号：US11029281B2
公开(公告)日：2021-06-08
申请号：US16333258
申请日：2016-09-23
IPC分类号： G01N27/447 , B05C7/08 , B29C45/50 , G01N1/14
摘要： This drive screw device is provided with: a drive screw; a drive unit which causes the drive screw to rotate; a slider which moves along the drive screw by means of the rotation of the drive screw; and an external load which is provided on the drive screw and applies a rotational load to the drive screw. By this means it is possible to provide a drive screw device with which there is little pressure variation even if a frictional force varies.
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公开(公告)号：US10884008B2
公开(公告)日：2021-01-05
申请号：US15309550
申请日：2015-04-27
摘要： Provided are: a device for storing biochemical reagents wherein an amount of a reagent can be hermetically stored and dropped from a storage site without coming into contact with the outside air; and a biochemical analyzer using the device. The device (10) is constituted by: sticking a top sheet (32) to a base sheet (31) provided with a convex-shaped hollow pocket (16) in which a reagent can be housed; a reagent container as a PTP packaging sheet (30) wherein an opening of the pocket in the base sheet (31), in which a reagent is preliminarily housed, is hermetically sealed with the top sheet (32); and sticking the film sheet surface as the top sheet (32) of the PTP packaging sheet (30), in which the reagent is hermetically packaged, to a cartridge surface of a device body (20) to thereby hermetically seal the inside of the device body too.
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7.发明申请公开(公告)号：US20150210999A1
公开(公告)日：2015-07-30
申请号：US14416146
申请日：2013-06-11
IPC分类号： C12N15/10 , C12Q1/68 , G01N27/447 , B01L7/00
CPC分类号： C12N15/101 , B01L3/5027 , B01L7/52 , B01L2200/028 , B01L2200/10 , B01L2300/0816 , B01L2400/0421 , B01L2400/0487 , C12Q1/6806 , C12Q1/686 , G01N27/44791 , C12Q2565/125 , C12Q2565/629 , C12Q2531/113
摘要： To allow fully automated implementation of all steps of from pre-processing up to electrophoresis. Provided is a pre-processing/electrophoresis integrated cartridge including one or more block structures corresponding to the individual steps of pre-processing. Each block structure includes (1) a first block having a reaction tank, a reagent tank, a plurality of flow channels that connect the tanks, a plurality of control valves arranged in the flow channels, and a flow channel that connects a reaction tank in a block structure located at a preceding stage and a reaction tank in a block structure located at a next stage, and (2) a second block having a phoretic solution tank, a cathode buffer solution tank, a wash solution tank, a flow channel that connects a carrier tank in the block structure located at the preceding stage and the phoretic solution tank, and a control valve for the flow channel.
摘要翻译： 允许全自动实现从预处理到电泳的所有步骤。 提供了一种预处理/电泳集成盒，其包括对应于预处理的各个步骤的一个或多个块结构。 每个块结构包括（1）具有反应罐，试剂罐，连接罐的多个流动通道，布置在流动通道中的多个控制阀的第一块和将反应罐连接在一起的流动通道 位于前一级的块结构和位于下一阶段的块结构中的反应槽，以及（2）具有沉淀溶液罐，阴极缓冲溶液罐，洗涤溶液罐的第二块，流动槽 将位于前一级的块结构中的载体槽和溶液槽连接，并且将流路的控制阀连接起来。
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公开(公告)号：US11442016B2
公开(公告)日：2022-09-13
申请号：US16076212
申请日：2016-02-22
发明人： Takashi Anazawa , Motohiro Yamazaki
IPC分类号： G01N21/64 , C12Q1/6869 , G02B3/00 , G02B27/14 , B01L3/00
摘要： The invention is directed to a light-emission detection apparatus for individually condensing light emitted from each emission point of a emission-point array using each condensing lens of a condensing-lens array to form a light beam and detecting each light beam incident on a sensor in parallel, and the light-emission detection apparatus can be downsized and high sensitivity and low crosstalk can be simultaneously accomplished when a certain relation between the diameter of each emission point, a focal length of each condensing lens, an interval of condensing lenses, and an optical path length between each condensing lens and a sensor is satisfied.
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公开(公告)号：US11243187B2
公开(公告)日：2022-02-08
申请号：US16620961
申请日：2017-06-28
发明人： Naomichi Kawasaki , Ryusuke Kimura , Katsuhiro Aritome , Go Nakajima , Takashi Gomi , Motohiro Yamazaki
IPC分类号： G01N27/447
摘要： The present invention addresses the problem of providing an electrophoretic medium container capable of stabilizing a liquid delivery pressure while ensuring sealing of an electrophoretic medium. In order to resolve this problem, this electrophoretic medium container is provided with a syringe part for holding an electrophoretic medium, and a sealing component for sealing one end of the syringe part, the electrophoretic medium container being characterized in that the sealing component has a sealing surface, a body part, and a groove provided between the sealing surface and the body part, wherein the sealing surface is in contact with the inner wall of the syringe part.
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公开(公告)号：US10753873B2
公开(公告)日：2020-08-25
申请号：US16205362
申请日：2018-11-30
IPC分类号： G01N21/64 , G01J3/44 , G01N27/447 , G01J3/02 , G01J3/14 , G01J3/18 , C12Q1/6869 , G01J3/12
摘要： A multicolor detection device includes: a condensing lens array 17 in which a plurality of condensing lenses 18, each of which turns light emitted from each of a plurality of light emitting points 1 individually into parallel light beams, are arranged, the light emitting points being arranged in a light emitting point array; at least one spectroscopic element on which the parallel light beams are incident in parallel, the at least one spectroscopic element being common; and at least one sensor on which light beams spectrally separated by the spectroscopic element are incident in parallel, the at least one sensor being common.
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