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1.发明授权公开(公告)号：US11426721B2
公开(公告)日：2022-08-30
申请号：US16313485
申请日：2017-06-26
Applicant: Hitachi High-Technologies Corporation
Inventor： Yoshihiro Nagaoka , Taro Nakazawa , Mitsuhiro Miyazaki , Ryusuke Kimura , Motohiro Yamazaki
Abstract: Provided are a bubble eliminating structure and a bubble eliminating method which eliminate bubbles in a liquid by agitating the liquid, and an agitating method using the same. A first groove 114, which is an upstream bubble eliminating groove, and a second groove 131, which is a downstream bubble eliminating groove, are branched from a mixing well 13. After starting suction of the liquid from mixing well 13 into the first groove 114, suction of the liquid from the mixing well 13 into the second groove 131 is started, and after completion of discharge of the liquid from the first groove 114 into the mixing well 13, discharge of the liquid from the second groove 131 into the mixing well 13 is completed. This operation is repeated to eliminate bubbles.
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公开(公告)号：US10451553B2
公开(公告)日：2019-10-22
申请号：US15129287
申请日：2015-03-18
Applicant: Hitachi High-Technologies Corporation
Inventor： Motohiro Yamazaki , Yuichiro Ota , Satoshi Takahashi , Yoshitaka Kodama
IPC: G01N21/64 , G01J3/44 , G01N27/447 , G01J3/02
Abstract: During analysis of samples of unknown concentration, situations frequently occur in which the dynamic range is insufficient, necessitating reanalysis. Accordingly, a fluorescence spectrometer which splits a single object image into multiple images having different fluorescent intensity by means of image splitting elements, and simultaneously detects the plurality of images obtained thereby in different regions within the same detection plane, is proposed.
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公开(公告)号：US10246675B2
公开(公告)日：2019-04-02
申请号：US14762301
申请日：2014-01-27
Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
Inventor： Ryusuke Kimura , Hiromi Yamashita , Motohiro Yamazaki , Taro Nakazawa
Abstract: A cartridge sealed from ambient air is used to send a liquid without causing the liquid to contact the fluid inside the cartridge. Inside of the cartridge 1 sealed from ambient air are provided chambers that send and receive reagents, and an elastic body membrane 51 is attached to the bottom surface. The cartridge main body 51 does not have a groove or anything else that becomes a channel, and the membrane 51 is not bonded to portions that become channels. A channel, not formed in a normal state, is formed upon deforming the membrane 51 under air pressure in the unbonded portion, and the fluid is moved inside. A valve function is provided at an inlet of each chamber, and the fluid is internally moved in any direction with channel deformation.
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公开(公告)号：US09492821B2
公开(公告)日：2016-11-15
申请号：US14770978
申请日：2014-01-30
Applicant: Hitachi High-Technologies Corporation
Inventor： Yoshihiro Nagaoka , Hisao Inami , Motohiro Yamazaki
CPC classification number: B01L3/502715 , B01F13/0083 , B01J19/00 , B01L3/502738 , B01L2200/0621 , B01L2300/0867 , B01L2300/0877 , B01L2400/0633
Abstract: In some examples, a liquid feeding device includes a main flow passage in which a fluid may be fed between an upstream side and a downstream side. A first flow passage may branch from the main flow passage, and may include a narrow flow passage at a terminal end portion, having a smaller cross-sectional area than the first flow passage. A liquid feeding mechanism may feed the fluid to the main flow passage and the first flow passage. The narrow flow passage may suppress the fluid from leaking from first flow passage. Thus, the liquid feeding device may quantitatively determine a first volume of the fluid by filling the first flow passage with the fluid, and subsequently feeding the quantitatively determined fluid back to the main flow passage.
Abstract translation: 在一些示例中，液体供给装置包括主流路，流体可以在上游侧和下游侧供给。 第一流路可以从主流路分支，并且在末端部可以包括具有比第一流路更小的横截面面积的窄流路。 液体供给机构可以将流体供给到主流路和第一流路。 狭窄的流动通道可以抑制流体从第一流动通道泄漏。 因此，液体供给装置可以通过用流体填充第一流路来定量地确定第一体积的流体，并且随后将定量确定的流体送回到主流动通道。
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公开(公告)号：US11442016B2
公开(公告)日：2022-09-13
申请号：US16076212
申请日：2016-02-22
Applicant: Hitachi High-Technologies Corporation
Inventor： Takashi Anazawa , Motohiro Yamazaki
IPC: G01N21/64 , C12Q1/6869 , G02B3/00 , G02B27/14 , B01L3/00
Abstract: The invention is directed to a light-emission detection apparatus for individually condensing light emitted from each emission point of a emission-point array using each condensing lens of a condensing-lens array to form a light beam and detecting each light beam incident on a sensor in parallel, and the light-emission detection apparatus can be downsized and high sensitivity and low crosstalk can be simultaneously accomplished when a certain relation between the diameter of each emission point, a focal length of each condensing lens, an interval of condensing lenses, and an optical path length between each condensing lens and a sensor is satisfied.
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Patent Agency Ranking
公开(公告)号：US11243187B2
公开(公告)日：2022-02-08
申请号：US16620961
申请日：2017-06-28
Applicant: Hitachi High-Technologies Corporation
Inventor： Naomichi Kawasaki , Ryusuke Kimura , Katsuhiro Aritome , Go Nakajima , Takashi Gomi , Motohiro Yamazaki
IPC: G01N27/447
Abstract: The present invention addresses the problem of providing an electrophoretic medium container capable of stabilizing a liquid delivery pressure while ensuring sealing of an electrophoretic medium. In order to resolve this problem, this electrophoretic medium container is provided with a syringe part for holding an electrophoretic medium, and a sealing component for sealing one end of the syringe part, the electrophoretic medium container being characterized in that the sealing component has a sealing surface, a body part, and a groove provided between the sealing surface and the body part, wherein the sealing surface is in contact with the inner wall of the syringe part.
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公开(公告)号：US10753873B2
公开(公告)日：2020-08-25
申请号：US16205362
申请日：2018-11-30
Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
Inventor： Takashi Anazawa , Satoshi Takahashi , Motohiro Yamazaki , Yoshitaka Kodama
IPC: G01N21/64 , G01J3/44 , G01N27/447 , G01J3/02 , G01J3/14 , G01J3/18 , C12Q1/6869 , G01J3/12
Abstract: A multicolor detection device includes: a condensing lens array 17 in which a plurality of condensing lenses 18, each of which turns light emitted from each of a plurality of light emitting points 1 individually into parallel light beams, are arranged, the light emitting points being arranged in a light emitting point array; at least one spectroscopic element on which the parallel light beams are incident in parallel, the at least one spectroscopic element being common; and at least one sensor on which light beams spectrally separated by the spectroscopic element are incident in parallel, the at least one sensor being common.
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公开(公告)号：US10175172B2
公开(公告)日：2019-01-08
申请号：US15548432
申请日：2015-02-03
Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION
Inventor： Takashi Anazawa , Satoshi Takahashi , Motohiro Yamazaki , Yoshitaka Kodama
IPC: G01N21/64 , G01J3/44 , C12Q1/6869 , G01N27/447
Abstract: A multicolor detection device includes: a condensing lens array 17 in which a plurality of condensing lenses 18, each of which turns light emitted from each of a plurality of light emitting points 1 individually into parallel light beams, are arranged, the light emitting points being arranged in a light emitting point array; at least one spectroscopic element on which the parallel light beams are incident in parallel, the at least one spectroscopic element being common; and at least one sensor on which light beams spectrally separated by the spectroscopic element are incident in parallel, the at least one sensor being common.
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公开(公告)号：US09415391B2
公开(公告)日：2016-08-16
申请号：US14416084
申请日：2013-06-18
Applicant: Hitachi High-Technologies Corporation
Inventor： Ryusuke Kimura , Hiromi Yamashita , Motohiro Yamazaki
IPC: B01L3/00
CPC classification number: B01L3/50273 , B01L3/502715 , B01L3/502723 , B01L3/502738 , B01L2200/0605 , B01L2300/0867 , B01L2300/087 , B01L2300/0874 , B01L2300/123 , B01L2400/0481 , B01L2400/0655
Abstract: A cartridge sealed from an external air is used to enable mixing with a reagent, agitating, purification, reaction, etc. Provided inside the cartridge sealed from the external air are a chamber for the reagent to be transported, a chamber to which the reagent is transported, and the chambers are connected by a liquid transport channel. A groove is made in a cartridge body and a membrane as an elastic body is pasted onto the groove to form the liquid transport channel. Air pressure is given to the membrane to change the volume of the liquid transport channel and thereby move the fluid inside. The inlet of each chamber has a valve function to move the fluid inside in a desired direction according to change of the liquid transport channel. This enables transportation of the liquid inside the cartridge sealed from the external air.
Abstract translation: 使用与外部空气密封的盒，以使其能够与试剂混合，搅拌，净化，反应等。在从外部空气密封的盒中设置有用于待运送试剂的室，试剂为 运输，并且室通过液体输送通道连接。 在盒体中形成凹槽，将作为弹性体的膜粘贴到凹槽上以形成液体输送通道。 给予膜的空气压力以改变液体输送通道的体积，从而使流体在内部移动。 每个室的入口具有阀功能，以根据液体输送通道的变化在所需方向内移动流体。 这使得能够将盒内的液体从外部空气密封。
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公开(公告)号：US11029281B2
公开(公告)日：2021-06-08
申请号：US16333258
申请日：2016-09-23
Applicant: Hitachi High-Technologies Corporation
Inventor： Katsuhiro Aritome , Ryusuke Kimura , Motohiro Yamazaki , Go Nakajima , Naomichi Kawasaki
IPC: G01N27/447 , B05C7/08 , B29C45/50 , G01N1/14
Abstract: This drive screw device is provided with: a drive screw; a drive unit which causes the drive screw to rotate; a slider which moves along the drive screw by means of the rotation of the drive screw; and an external load which is provided on the drive screw and applies a rotational load to the drive screw. By this means it is possible to provide a drive screw device with which there is little pressure variation even if a frictional force varies.
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