公开(公告)号：US10229821B2

公开(公告)日：2019-03-12

申请号：US15542505

申请日：2016-01-04

Applicant: Hitachi High-Technologies Corporation

Inventor： Kiyomi Yoshinari ,  Yasushi Terui

IPC: H01J49/00 ,  G01N27/62 ,  H01J49/42

Abstract: With regard to an object of the invention, in a tandem type mass spectrometry system including three stages of a QMS, sensitivity of a daughter ion decreases due to loss resulting from destabilization of the daughter ion or a decrease in daughter ion generation rate, and an improvement insensitivity of the daughter ion is a significant issue. To solve the above-mentioned problem, the invention provides a mass spectrometry system having means of decreasing a q value of a parent ion and not decreasing a fundamental vibration frequency of the parent ion. According to the means of the invention, the invention may have effects that a mass number range of a daughter ion that may be stably transmitted is expanded, the number of vibrations of a parent ion is substantially the same as that in a first stage of the QMS, and generation efficiency of the daughter ion does not decrease and can be maintained.

公开(公告)号：US10607825B2

公开(公告)日：2020-03-31

申请号：US16060132

申请日：2016-11-09

Applicant: Hitachi High-Technologies Corporation

Inventor： Kiyomi Yoshinari ,  Yasushi Terui

IPC: H01J49/00 ,  H01J49/06 ,  H01J49/42

Abstract: Acceleration of decelerated ions and a reduction in the velocity dispersion width of decelerated ions are both achieved, whereby the sensitivity of detected ion sensitivity is improved and resolution is improved. The distance dx between at least one set of facing rod-shaped electrodes among rod-shaped electrodes (4-2-a) to (4-2-d) differs at the inlet part at which ions enter and the outlet part at which ions exit, and the distance dx between the at least one set of facing rod-shaped electrodes is gradually reduced or increased from the inlet part toward the outlet part.

公开(公告)号：US10332736B2

公开(公告)日：2019-06-25

申请号：US14773902

申请日：2014-01-24

Applicant: Hitachi High-Technologies Corporation

Inventor： Kiyomi Yoshinari ,  Yasushi Terui

IPC: H01J49/00 ,  H01J49/04 ,  H01J49/42

Abstract: An object of the invention is to provide a mass spectrometer system capable of obtaining a mass spectrum with high resolution as the mass number of an ion becomes higher. In the mass spectrometer system of the invention, a control unit 8 controls a mass spectrometry unit 4 so that a direct current voltage U, an amplitude V of a radio-frequency voltage, and a frequency F of the radio-frequency voltage, which are applied to a quadrupole electrode 13, are increased as a mass-to-charge ratio m/z of an ion of a target for mass spectrometry becomes larger. By controlling in this manner, the ion frequency when the ion passes through the inside of the mass spectrometry unit 4 is increased as the mass number of an ion becomes higher, and therefore, it is possible to obtain the mass spectrum with higher resolution.

公开(公告)号：US10068756B2

公开(公告)日：2018-09-04

申请号：US15318858

申请日：2015-05-11

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Kiyomi Yoshinari ,  Yasushi Terui

IPC: H01J49/06 ,  H01J49/10 ,  H01J49/42

Abstract: The objective of the presently disclosed subject matter is to provide a mass spectrometer that improves the ionic permeability ratio at the entrance to an ion transport part or the entrance to a mass spectrometry part, and to acquire a high-sensitivity mass spectrum. To reduce the electric-field distortion that is caused by ion loss, electrodes are arranged so that the radius of a circle inscribed within the electrodes of the ion transport part is larger than the radius of a circle inscribed within the electrodes of the mass spectrometry part. The entrance to the electrodes of the mass spectrometry part also can have a tapered, inclined, folded-over, or rounded configuration. Together, these reduce the sharply fluctuating (peak-shaped) distribution of electric potential generated near the entrance to the ion transport part and the entrance to the mass spectrometry part.

公开(公告)号：US20170125230A1

公开(公告)日：2017-05-04

申请号：US15318858

申请日：2015-05-11

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Kiyomi Yoshinari ,  Yasushi Terui

IPC: H01J49/06 ,  H01J49/42 ,  H01J49/10

CPC classification number: H01J49/063 ,  H01J49/065 ,  H01J49/10 ,  H01J49/42 ,  H01J49/4215 ,  H01J49/4255

Abstract: The objective of the presently disclosed subject matter is to provide a mass spectrometer that improves the ionic permeability ratio at the entrance to an ion transport part or the entrance to a mass spectrometry part, and to acquire a high-sensitivity mass spectrum. To reduce the electric-field distortion that is caused by ion loss, electrodes are arranged so that the radius of a circle inscribed within the electrodes of the ion transport part is larger than the radius of a circle inscribed within the electrodes of the mass spectrometry part. The entrance to the electrodes of the mass spectrometry part also can have a tapered, inclined, folded-over, or rounded configuration. Together, these reduce the sharply fluctuating (peak-shaped) distribution of electric potential generated near the entrance to the ion transport part and the entrance to the mass spectrometry part.