公开(公告)号：US20180017492A1

公开(公告)日：2018-01-18

申请号：US15545422

申请日：2015-02-02

Applicant: Hitachi High-Technologies Corporation

Inventor： Hirokazu KATO ,  Tomohiro SHOJI ,  Satoshi TAKAHASHI ,  Akira MAEKAWA

IPC: G01N21/64

CPC classification number: G01N21/64 ,  G01N21/6454 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6471 ,  G01N2021/6484

Abstract: A multicolor fluorescence analysis device 1 according to the present invention is provided with: an irradiation unit 41 for irradiating excitation light having a plurality of excitation wavelength bands onto a sample s; a first fiberoptic plate 424 for guiding light including fluorescence emitted from the sample s as a result of the irradiation of the excitation light and emitting the same from a first emission part 425b; a second fiberoptic plate 431 for receiving light emitted from the first emission part 425b at a second incidence part 434a, guiding the same, and emitting the same from a second emission part 434b; a single multilayer dielectric interference film filter 432 that is provided on an end surface of the second emission part 434b, transmits at least a portion of the fluorescence, and transmits light of a plurality of transmission wavelength bands that do not include the excitation wavelength bands; and a two-dimensional detection unit 433 that is disposed so as to be adhered to the multilayer dielectric interference film filter 432 and detect light having passed through the multilayer dielectric interference film filter 432.

公开(公告)号：US20140038274A1

公开(公告)日：2014-02-06

申请号：US14051540

申请日：2013-10-11

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Akira MAEKAWA ,  Tomoyuki SAKAI ,  Tsuyoshi SONEHARA ,  Satoshi TAKAHASHI

IPC: G01N21/64

CPC classification number: G01N21/6486 ,  C12Q1/6837 ,  G01N21/6452 ,  Y10T436/143333 ,  C12Q2565/513

Abstract: The present invention relates to a nucleic acid analysis device in a nucleic acid analysis apparatus, whereby waste of reaction spots on the nucleic acid analysis device is eliminated and leakage of fluorescence excitation light to unobserved nucleic acid measurement regions is minimized. Specifically, the nucleic acid analysis device has a plurality of nucleic acid measurement regions, which are characterized in that one nucleic acid measurement region is disposed at a sufficient distance from the other nucleic acid measurement regions such that the other nucleic acid measurement regions do not enter an irradiation region.

Abstract translation: 本发明涉及核酸分析装置中的核酸分析装置，其中消除了核酸分析装置上的反应点的浪费，使荧光激发光向未观察到的核酸测量区域的泄漏最小化。 具体而言，核酸分析装置具有多个核酸测定区域，其特征在于，将一个核酸测定区域配置在距离其他核酸测定区域足够的距离，使得其他核酸测定区域不进入 照射区域。

公开(公告)号：US20190107491A1

公开(公告)日：2019-04-11

申请号：US16205362

申请日：2018-11-30

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Takashi ANAZAWA ,  Satoshi TAKAHASHI ,  Motohiro YAMAZAKI ,  Yoshitaka KODAMA

IPC: G01N21/64 ,  G01J3/44 ,  G01N27/447 ,  C12Q1/6869

CPC classification number: G01N21/6452 ,  C12Q1/6869 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/14 ,  G01J3/18 ,  G01J3/4406 ,  G01J2003/1217 ,  G01N21/6428 ,  G01N27/447 ,  G01N27/44721 ,  G01N2021/6441 ,  G01N2021/6471 ,  G01N2021/6478

Abstract: A multicolor detection device includes: a condensing lens array 17 in which a plurality of condensing lenses 18, each of which turns light emitted from each of a plurality of light emitting points 1 individually into parallel light beams, are arranged, the light emitting points being arranged in a light emitting point array; at least one spectroscopic element on which the parallel light beams are incident in parallel, the at least one spectroscopic element being common; and at least one sensor on which light beams spectrally separated by the spectroscopic element are incident in parallel, the at least one sensor being common.

公开(公告)号：US20170115223A1

公开(公告)日：2017-04-27

申请号：US15129287

申请日：2015-03-18

Applicant: Hitachi High-Technologies Corporation

Inventor： Motohiro YAMAZAKI ,  Yuichiro OTA ,  Satoshi TAKAHASHI ,  Yoshitaka KODAMA

IPC: G01N21/64 ,  G01N27/447

CPC classification number: G01N21/6456 ,  G01J3/0208 ,  G01J3/4406 ,  G01N27/447 ,  G01N27/44721 ,  G01N2021/6417 ,  G01N2021/6471 ,  G01N2201/06113

Abstract: During analysis of samples of unknown concentration, situations frequently occur in which the dynamic range is insufficient, necessitating reanalysis. Accordingly, a fluorescence spectrometer which splits a single object image into multiple images having different fluorescent intensity by means of image splitting elements, and simultaneously detects the plurality of images obtained thereby in different regions within the same detection plane, is proposed.

公开(公告)号：US20180024061A1

公开(公告)日：2018-01-25

申请号：US15548432

申请日：2015-02-03

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Takashi ANAZAWA ,  Satoshi TAKAHASHI ,  Motohiro YAMAZAKI ,  Yoshitaka KODAMA

IPC: G01N21/64 ,  C12Q1/68

CPC classification number: G01N21/6452 ,  C12Q1/6869 ,  G01J3/4406 ,  G01N21/6428 ,  G01N27/447 ,  G01N27/44721 ,  G01N2021/6441 ,  G01N2021/6471 ,  G01N2021/6478

Abstract: A multicolor detection device includes: a condensing lens array 17 in which a plurality of condensing lenses 18, each of which turns light emitted from each of a plurality of light emitting points 1 individually into parallel light beams, are arranged, the light emitting points being arranged in a light emitting point array; at least one spectroscopic element on which the parallel light beams are incident in parallel, the at least one spectroscopic element being common; and at least one sensor on which light beams spectrally separated by the spectroscopic element are incident in parallel, the at least one sensor being common.