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公开(公告)号:US20110125050A1
公开(公告)日:2011-05-26
申请号:US12897207
申请日:2010-10-04
申请人: Haim H. Bau , Michael G. Schrlau , Rui Zhang
发明人: Haim H. Bau , Michael G. Schrlau , Rui Zhang
CPC分类号: B01L3/0275 , B01L2200/12 , B01L2300/0645 , B01L2300/0838 , B01L2300/0896 , B82Y30/00 , B82Y35/00 , G01N33/48728
摘要: Provided are probes featuring multiple electrodes, which probes have diameters in the nanometer range and may be inserted into cells or other subjects so as to monitor an electrical characteristic of the subject. The probes may also include a conductive coating on at least one probe element to improve the probes' performance. The probes may also be used to inject a fluid or other agent into the subject and simultaneously monitor changes in the subject's electrical characteristics in response to the injection. Related methods of fabricating and of using the inventive probes are also provided.
摘要翻译: 提供了具有多个电极的探针,其探针具有纳米范围的直径并且可以插入细胞或其他受试者中,以便监测受试者的电特性。 探针还可以包括至少一个探针元件上的导电涂层以改善探针的性能。 探针还可以用于将流体或其它试剂注射到受试者中并且同时监测受试者响应于注射的电特征的变化。 还提供了制造和使用本发明的探针的相关方法。
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公开(公告)号:US08702927B2
公开(公告)日:2014-04-22
申请号:US13263234
申请日:2010-04-23
申请人: Haim H. Bau , Michael G. Schrlau , Rui Zhang
发明人: Haim H. Bau , Michael G. Schrlau , Rui Zhang
CPC分类号: G01N33/48728
摘要: Provided are probes featuring multiple electrodes, which probes have diameters in the nanometer range and may be inserted into cells or other subjects so as to monitor an electrical characteristic of the subject. The probes may also include a conductive coating on at least one probe element to improve the probes' performance. The probes may also be used to inject a fluid or other agent into the subject and simultaneously monitor changes in the subject's electrical characteristics in response to the injection. Related methods of fabricating and of using the inventive probes are also provided.
摘要翻译: 提供了具有多个电极的探针,其探针具有纳米范围的直径并且可以插入细胞或其他受试者中,以便监测受试者的电特性。 探针还可以包括至少一个探针元件上的导电涂层以改善探针的性能。 探针还可以用于将流体或其它试剂注射到受试者中并且同时监测受试者响应于注射的电特征的变化。 还提供了制造和使用本发明的探针的相关方法。
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公开(公告)号:US20120282644A1
公开(公告)日:2012-11-08
申请号:US13263234
申请日:2010-04-23
申请人: Haim H. Bau , Michael G. Schrlau , Rui Zhang
发明人: Haim H. Bau , Michael G. Schrlau , Rui Zhang
CPC分类号: G01N33/48728
摘要: Provided are probes featuring multiple electrodes, which probes have diameters in the nanometer range and may be inserted into cells or other subjects so as to monitor an electrical characteristic of the subject. The probes may also include a conductive coating on at least one probe element to improve the probes' performance. The probes may also be used to inject a fluid or other agent into the subject and simultaneously monitor changes in the subject's electrical characteristics in response to the injection. Related methods of fabricating and of using the inventive probes are also provided.
摘要翻译: 提供了具有多个电极的探针,其探针具有纳米范围的直径并且可以插入细胞或其他受试者中,以便监测受试者的电特性。 探针还可以包括至少一个探针元件上的导电涂层以改善探针的性能。 探针还可以用于将流体或其它试剂注射到受试者中并且同时监测受试者响应于注射的电特征的变化。 还提供了制造和使用本发明的探针的相关方法。
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公开(公告)号:US20130037423A1
公开(公告)日:2013-02-14
申请号:US13421944
申请日:2012-03-16
申请人: Michael G. Schrlau , Eugen Brailoiu , Nae J. Dun , Haim H. Bau
发明人: Michael G. Schrlau , Eugen Brailoiu , Nae J. Dun , Haim H. Bau
IPC分类号: G01N27/26
CPC分类号: G01N33/48728
摘要: Provided are devices and methods for performing multi-point analysis on biological materials, such as cells. In one embodiment, the devices simultaneously collect information related to a characteristic of a cell membrane and a characteristic of the interior of the cell.
摘要翻译: 提供了用于对诸如细胞的生物材料进行多点分析的装置和方法。 在一个实施例中,装置同时收集与细胞膜的特征和细胞内部的特征相关的信息。
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