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公开(公告)号：US5408280A
公开(公告)日：1995-04-18
申请号：US805733
申请日：1991-12-09
摘要： The invention relates to a process for rendering contact lenses hydrophilic, which comprises treating a contact lens with a compound of formula IAr--Z--Ar' (I)wherein Ar and Ar' are each independently of the other an aromatic radical that may be substituted by lower alkoxy and/or by lower alkyl and wherein one of the radicals Ar and Ar' or both radicals Ar and Ar' contain one or more substituents X selected independently of one another from a polar functional group Y, lower alkyl substituted by a polar functional group Y, and lower alkoxy substituted by a polar functional group Y, and wherein Z is a divalent group that separates Ar and Ar' from each other by from one to six atoms. The invention relates also to contact lenses treated according to the invention and to the use of compounds of formula I in the process according to the invention.
摘要翻译： 本发明涉及一种使隐形眼镜亲水化的方法，其包括用式I Ar-Z-Ar'（I）化合物处理隐形眼镜，其中Ar和Ar'各自独立地为可以是芳族基团 被低级烷氧基和/或被低级烷基取代，并且其中一个基团Ar和Ar'或两个基团Ar和Ar'含有一个或多个从极性官能团Y彼此独立选择的取代基X，被 极性官能团Y和被极性官能团Y取代的低级烷氧基，其中Z是使Ar和Ar'彼此分开1至6个原子的二价基团。 本发明还涉及根据本发明处理的隐形眼镜和根据本发明的方法中式I化合物的用途。
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公开(公告)号：US4828996A
公开(公告)日：1989-05-09
申请号：US455496
申请日：1983-01-04
申请人： Rolf Siegel
发明人： Rolf Siegel
IPC分类号： C12N11/02
CPC分类号： C12N11/02
摘要： Materials and a method of their preparation are described, for use in immobilizing soluble, biologically active compounds. The material for immobilizing includes a hydrophobic, water insoluble substrate having a coating of a mixture of different amphiphilic lipoid compounds thereon. The lipoid compounds are oriented so that the hydrophilic portions are distal to the substrate and free to bond with water soluble proteins and carbohydrates.
摘要翻译： 描述了用于固定可溶性生物活性化合物的材料及其制备方法。 用于固定的材料包括在其上具有不同两亲性脂质化合物的混合物的涂层的疏水性水不溶性底物。 脂质化合物被取向为使得亲水部分位于底物的远侧并且与水溶性蛋白质和碳水化合物自由键合。
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公开(公告)号：US20210395471A1
公开(公告)日：2021-12-23
申请号：US17296059
申请日：2019-11-25
申请人： Rolf SIEGEL , Kurtz GmbH
发明人： Rolf Siegel
摘要： The present invention relates to methods for the welding of foam particles, by electromagnetic waves, wherein foam particles with a surface modification are welded in a molding tool by electromagnetic waves, wherein the surface modification is produced by contacting the foam particles with a solution containing polymers which are capable of forming intra- or inter-molecular covalent bonds, under the conditions required for this purpose.
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4.发明授权公开(公告)号：US06855740B2
公开(公告)日：2005-02-15
申请号：US10469045
申请日：2002-02-26
申请人： Rolf Siegel
发明人： Rolf Siegel
CPC分类号： C08J9/08 , C08J9/0028 , C08J9/04 , C08J2383/04
摘要： Molded foam bodies made of silicone can be produced in large series by means of known injection molding machines for liquid silicone by virtue of the fact that mixtures of ammonium carbonate, and/or ammonium carbaminate, and/or ammonium hydrogen carbonate, in powdered form, and at least one of the two liquid-paste-like components of liquid silicone are produced and the two liquid silicone components are then processed in the known manner, with the proviso that the mold is not completely filled with the dispersion.
摘要翻译： 通过已知的液体硅酮注射成型机可以大量生产由硅酮制成的模制泡沫体，原因在于粉末形式的碳酸铵和/或氨基甲酸铵和/或碳酸氢铵的混合物， 并且制备液体硅氧烷的两个液体糊状组分中的至少一个，然后以已知的方式处理两个液体硅氧烷组分，条件是模具未完全填充分散体。
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公开(公告)号：US09938648B2
公开(公告)日：2018-04-10
申请号：US13982973
申请日：2012-02-02
申请人： Rolf Siegel
发明人： Rolf Siegel
IPC分类号： B05D3/02 , D04H1/64 , A61L15/52 , A61L27/50 , D06M15/333 , D06M15/356 , D06P1/52 , D06P5/22
CPC分类号： D04H1/64 , A61L15/52 , A61L27/50 , D06M15/333 , D06M15/3568 , D06P1/5228 , D06P1/5292 , D06P5/22 , Y10T428/249921 , Y10T428/249924
摘要： The invention relates to a wet chemical method for the surface modification of products made of low-energy synthetic fibers, to the products produced by the method and to the use of the products produced by the method. The material surface is permanently provided with functional groups by contact with an aqueous polyvinylalcohol solution containing silanol(ate) groups. Depending upon the design, the materials have a high water consumption or transmission capacity or exhibit a capillary activity. The range of uses for surface-modified materials is extended by the possibility of reacting the functional groups, inter alia, with biologically active components.
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6.发明授权Method for wet chemical surface modification of formed polysiloxane products and coated substrates silicones 失效形成的聚硅氧烷产品和涂覆基质硅氧烷的湿化学表面改性方法
公开(公告)号：US5494756A
公开(公告)日：1996-02-27
申请号：US62646
申请日：1993-05-14
申请人： Rolf Siegel
发明人： Rolf Siegel
CPC分类号： C08J7/12 , C08J2383/04 , Y10S385/90 , Y10S428/907 , Y10T428/31663
摘要： A procedure is described for wet chemical surface modification of formed articles and substrates coated with made of organopolysiloxanes: the articles formed were contacted with metal hydroxide solutions to tailor the binding capacity for ions, particularly metal ions, bivalent cations, organic macro anions, and organic macro cations, e.g. proteins. The procedure creates organopolysiloxane surfaces which are better wettable, have reduced surface resistance, are less sticky, are smoother and more biocompatible.
摘要翻译： 描述了用有机聚硅氧烷制成的成型制品和基材的湿化学表面改性的方法：将形成的制品与金属氢氧化物溶液接触以调节离子，特别是金属离子，二价阳离子，有机大分子阴离子和有机物的结合能力 宏观阳离子，例如 蛋白质。 该方法产生有机聚硅氧烷表面，其具有更好的可润湿性，降低的表面电阻，较少的粘性，更平滑和更生物相容性。
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公开(公告)号：US20090041823A1
公开(公告)日：2009-02-12
申请号：US10572447
申请日：2004-09-18
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/00 , C08L83/04
摘要： The invention relates to a prosthesis comprising a proximal and a distal end and a hollow space that extends there-between. Said prosthesis is provided with a support structure and at least one biologically active compound.
摘要翻译： 本发明涉及一种假体，其包括近端和远端以及在其之间延伸的中空空间。 所述假体具有支撑结构和至少一种生物活性化合物。
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