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公开(公告)号：US4468171A
公开(公告)日：1984-08-28
申请号：US445177
申请日：1982-11-29
申请人： Haruo Katsumata , Takeshi Matsuya , Hitoshi Saitoh , Shigeru Yasuki , Yukio Sato , Masaru Osaki , Minoru Komeno , Takayuki Arai , Shigeki Ochi , Tatsuo Ino
发明人： Haruo Katsumata , Takeshi Matsuya , Hitoshi Saitoh , Shigeru Yasuki , Yukio Sato , Masaru Osaki , Minoru Komeno , Takayuki Arai , Shigeki Ochi , Tatsuo Ino
CPC分类号： F04D27/00 , F04D27/002 , G05D7/0676
摘要： The air flow rate of a fan driven by a motor controlled by an adjustable speed control equipment is automatically controlled by stopping the adjustable speed control equipment in response to a fault signal therefrom during operation with an inlet vane installed upstream of the fan in fully open state, simultaneously throttling the inlet vane at a preset speed to a degree of opening appropriate for the load by means of a control circuit, and, after a period for reduction of residual voltage of the motor, changing over to operation of the fan by a commercial power supply thereby to shift to control by the degree of opening of the inlet vane.
摘要翻译： 由可调节速度控制设备控制的电动机驱动的风扇的空气流量通过在运行期间停止可调节速度控制设备以响应于其中的故障信号而被自动控制，其中风扇安装在完全打开状态的入口叶片 同时通过控制电路将入口叶片以预设的速度节流到适合于负载的开度，并且在用于减小电动机的剩余电压的时间段之后，通过商业转换到风扇的操作 电源从而通过入口叶片的打开程度转移到控制。
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公开(公告)号：US06569634B1
公开(公告)日：2003-05-27
申请号：US09530453
申请日：2000-05-01
IPC分类号： G01N33574
CPC分类号： G01N33/573 , G01N2333/91011
摘要： This invention relates to a method for immunologically measuring human thymidylate synthase with an anti-human thymidylate synthase antibody, wherein as the antibody, at least an anti-human thymidylate synthase polyclonal antibody immobilized on an insoluble matrix is used; a method for evaluating sensitivity of cancer cells to a fluoropyrimidine antitumor drug from the results of the measurement by the measuring method; and a human thymidylate synthase measuring kit comprising an insoluble matrix with at least one anti-human thymidylate synthase polyclonal antibody immobilized thereon. By a simple immunological measuring method, human TS in a sample can be measured with high sensitivity.
摘要翻译： 本发明涉及一种用抗人胸苷酸合酶抗体免疫测定人胸苷酸合酶的方法，其中使用至少一种固定在不溶性基质上的抗人胸苷酸合酶多克隆抗体作为该抗体; 通过测量方法从测量结果评估癌细胞对氟嘧啶抗肿瘤药物的敏感性的方法; 和人胸苷酸合酶测定试剂盒，其包含固定有至少一种抗人胸苷酸合酶多克隆抗体的不溶性基质。 通过简单的免疫学测量方法，可以高灵敏度地测量样品中的人TS。
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公开(公告)号：US20090215198A1
公开(公告)日：2009-08-27
申请号：US12434174
申请日：2009-05-01
申请人： Atsushi Miyamoto , Tokio Sawai , Takeshi Matsuya , Tsuneo Okuyama
发明人： Atsushi Miyamoto , Tokio Sawai , Takeshi Matsuya , Tsuneo Okuyama
IPC分类号： G01N33/566
CPC分类号： G01N33/585 , G01N33/54313 , G01N2333/315 , G01N2333/765 , G01N2333/96472
摘要： An immunological latex turbidimetry method for analyzing an antigen or antibody in a sample, comprising steps of: (1) bringing a sample which may contain the antigen or antibody to be analyzed into contact with a protease-treated albumin; and (2) bringing a mixture obtained in the above step (1) into contact with latex particles carrying an antibody or antigen specifically reacting with the antigen or antibody to be assayed, and analyzing a turbidity caused by a latex agglutination reaction, is disclosed. Further, an immunological latex turbidimetry reagent comprising (1) a first component containing a protease-treated albumin, and (2) a second component containing latex particles carrying an antibody or antigen specifically reacting with an antigen or antibody to be assayed is also disclosed.
摘要翻译： 一种用于分析样品中的抗原或抗体的免疫乳胶比浊法，包括以下步骤：（1）使可能含有待分析的抗原或抗体的样品与经蛋白酶处理的白蛋白接触; 和（2）将上述步骤（1）中获得的混合物与携带抗体或抗原特异性反应的胶原颗粒接触，并分析由胶乳凝集反应引起的浊度。 此外，还公开了一种免疫乳胶比浊法，其包含（1）含有蛋白酶处理的白蛋白的第一成分和（2）含有携带抗体或抗原的胶乳颗粒的第二成分，所述抗体或抗原与待测定的抗原或抗体特异性反应。
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公开(公告)号：US07560238B2
公开(公告)日：2009-07-14
申请号：US10048212
申请日：2001-05-30
申请人： Atsushi Miyamoto , Tokio Sawai , Takeshi Matsuya , Tsuneo Okuyama
发明人： Atsushi Miyamoto , Tokio Sawai , Takeshi Matsuya , Tsuneo Okuyama
IPC分类号： G01N33/00
CPC分类号： G01N33/585 , G01N33/54313 , G01N2333/315 , G01N2333/765 , G01N2333/96472
摘要： An immunological latex turbidimetry method for analyzing an antigen or antibody in a sample is disclosed, comprising steps of (1) bringing a sample which may contain the antigen or antibody to be analyzed into contact with a protease-treated albumin, and (2) bringing a mixture obtained in the above step (1) into contact with latex particles carrying an antibody or antigen specifically reacting with the antigen or antibody to be assayed, and analyzing a turbidity caused by a latex agglutination reaction. Also disclosed is an immunological latex turbidimetry reagent comprising (1) a first component containing a protease-treated albumin, and (2) a second component containing latex particles carrying an antibody or antigen specifically reacting with an antigen or antibody to be assayed.
摘要翻译： 公开了一种用于分析样品中的抗原或抗体的免疫乳胶比浊法，其包括以下步骤：（1）使可能含有待分析的抗原或抗体的样品与蛋白酶处理的白蛋白接触，和（2）使 将上述步骤（1）中获得的混合物与携带与要测定的抗原或抗体特异性反应的抗体或抗原的胶乳颗粒接触，并分析由胶乳凝集反应引起的浊度。 还公开了一种免疫乳胶比浊法，其包含（1）含有蛋白酶处理的白蛋白的第一成分，和（2）含有携带抗体或抗原的胶乳颗粒的第二成分，所述抗体或抗原与要测定的抗原或抗体特异性反应。
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公开(公告)号：US11041864B2
公开(公告)日：2021-06-22
申请号：US13979133
申请日：2012-01-10
申请人： Takeshi Matsuya , Yoshikazu Okamura , Ralf Thomae , Eberhard Spanuth , Boris Ivandic , Kamon Shirakawa , Shigeatsu Endo
发明人： Takeshi Matsuya , Yoshikazu Okamura , Ralf Thomae , Eberhard Spanuth , Boris Ivandic , Kamon Shirakawa , Shigeatsu Endo
摘要： Disclosed is a prediction method for the prognosis of sepsis comprising measuring an sCD14-ST level in a sample. sCD14-ST, to be measured in the present invention, is a marker superior to procalcitonin, known as a marker to predict the prognosis in sepsis patients.
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公开(公告)号：US07759074B2
公开(公告)日：2010-07-20
申请号：US12434174
申请日：2009-05-01
申请人： Atsushi Miyamoto , Tokio Sawai , Takeshi Matsuya , Tsuneo Okuyama
发明人： Atsushi Miyamoto , Tokio Sawai , Takeshi Matsuya , Tsuneo Okuyama
IPC分类号： G01N33/543 , G01N33/53
CPC分类号： G01N33/585 , G01N33/54313 , G01N2333/315 , G01N2333/765 , G01N2333/96472
摘要： An immunological latex turbidimetry method for analyzing an antigen or antibody in a sample, comprising the steps of: (1) bringing a sample which may contain the antigen or antibody to be analyzed into contact with a protease-treated albumin; and (2) bringing a mixture obtained in the above step (1) into contact with latex particles carrying an antibody or antigen specifically reacting with the antigen or antibody to be assayed, and analyzing a turbidity caused by a latex agglutination reaction, is disclosed. Further, an immunological latex turbidimetry reagent comprising (1) a first component containing a protease-treated albumin, and (2) a second component containing latex particles carrying an antibody or antigen specifically reacting with an antigen or antibody to be assayed is also disclosed.
摘要翻译： 一种用于分析样品中的抗原或抗体的免疫乳胶比浊法，其包括以下步骤：（1）使可能含有待分析的抗原或抗体的样品与蛋白酶处理的白蛋白接触; 和（2）将上述步骤（1）中获得的混合物与携带抗体或抗原特异性反应的胶原颗粒接触，并分析由胶乳凝集反应引起的浊度。 此外，还公开了一种免疫乳胶比浊法，其包含（1）含有蛋白酶处理的白蛋白的第一成分和（2）含有携带抗体或抗原的胶乳颗粒的第二成分，所述抗体或抗原与待测定的抗原或抗体特异性反应。
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公开(公告)号：US20130288276A1
公开(公告)日：2013-10-31
申请号：US13979133
申请日：2012-01-10
申请人： Takeshi Matsuya , Yoshikazu Okamura , Ralf Thomae , Eberhard Spanuth , Boris Ivandic , Kamon Shirakawa , Shigeatsu Endo
发明人： Takeshi Matsuya , Yoshikazu Okamura , Ralf Thomae , Eberhard Spanuth , Boris Ivandic , Kamon Shirakawa , Shigeatsu Endo
IPC分类号： G01N33/68
CPC分类号： G01N33/6893 , G01N2333/70596 , G01N2800/26 , G01N2800/52
摘要： Disclosed is a prediction method for the prognosis of sepsis comprising measuring an sCD14-ST level in a sample. sCD14-ST, to be measured in the present invention, is a marker superior to procalcitonin, known as a marker to predict the prognosis in sepsis patients.
摘要翻译： 公开了一种用于预测败血症的预测方法，其包括测量样品中的sCD14-ST水平。 在本发明中测量的sCD14-ST是优于降钙素原的标记，被称为预测败血症患者预后的标志物。
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8.发明授权公开(公告)号：US07888057B2
公开(公告)日：2011-02-15
申请号：US11912474
申请日：2006-04-27
申请人： Takeshi Matsuya
发明人： Takeshi Matsuya
IPC分类号： G01N33/53
CPC分类号： G01N33/86 , G01N21/76 , G01N33/54326 , G01N2333/75 , G01N2333/968 , G01N2800/12 , G01N2800/226 , Y10S435/81 , Y10S435/975
摘要： A method of immunologically analyzing plasmin-digested products of stabilized fibrin, characterized by using a combination of a monoclonal antibody (a) which does not react with stabilized fibrin, fibrinogen, and plasmin-digested products of fibrinogen, but reacts with a neoantigen which is newly exposed in a D domain by digesting stabilized fibrin with plasmin, and a monoclonal antibody (b) which recognizes a site different from that recognized by the monoclonal antibody (a), and specifically reacts with plasmin-digested products of stabilized fibrin, wherein one of the monoclonal antibodies (a) and (b) is carried on a magnetic particle, and the other is labeled with an enzyme, and a chemiluminescent substrate is used as a substrate for the enzyme, is disclosed.
摘要翻译： 一种免疫分析稳定纤维蛋白溶解纤溶酶消化产物的方法，其特征在于使用不与纤维蛋白原的稳定的纤维蛋白，纤维蛋白原和纤维蛋白溶解的产物反应的单克隆抗体（a）的组合，但与新抗原反应 通过用纤溶酶消化稳定的纤维蛋白而在D结构域中新近暴露，以及识别与单克隆抗体（a）识别的位点不同的位点的单克隆抗体（b），并且与纤维蛋白溶解的稳定的纤维蛋白产物特异性反应，其中一个 的单克隆抗体（a）和（b）携带在磁性颗粒上，另一种用酶标记，化学发光底物用作酶的底物。
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公开(公告)号：US20090068682A1
公开(公告)日：2009-03-12
申请号：US11912474
申请日：2006-04-27
申请人： Takeshi Matsuya
发明人： Takeshi Matsuya
IPC分类号： G01N33/53
CPC分类号： G01N33/86 , G01N21/76 , G01N33/54326 , G01N2333/75 , G01N2333/968 , G01N2800/12 , G01N2800/226 , Y10S435/81 , Y10S435/975
摘要： A method of immunologically analyzing plasmin-digested products of stabilized fibrin, characterized by using a combination of a monoclonal antibody (a) which does not react with stabilized fibrin, fibrinogen, and plasmin-digested products of fibrinogen, but reacts with a neoantigen which is newly exposed in a D domain by digesting stabilized fibrin with plasmin, and a monoclonal antibody (b) which recognizes a site different from that recognized by the monoclonal antibody (a), and specifically reacts with plasmin-digested products of stabilized fibrin, wherein one of the monoclonal antibodies (a) and (b) is carried on a magnetic particle, and the other is labeled with an enzyme, and a chemiluminescent substrate is used as a substrate for the enzyme, is disclosed.
摘要翻译： 一种免疫分析稳定纤维蛋白溶解纤溶酶消化产物的方法，其特征在于使用不与纤维蛋白原的稳定的纤维蛋白，纤维蛋白原和纤维蛋白溶解的产物反应的单克隆抗体（a）的组合，但与新抗原反应 通过用纤溶酶消化稳定的纤维蛋白而在D结构域中新近暴露，以及识别与单克隆抗体（a）识别的位点不同的位点的单克隆抗体（b），并且与纤维蛋白溶解的稳定的纤维蛋白产物特异性反应，其中一个 的单克隆抗体（a）和（b）携带在磁性颗粒上，另一种用酶标记，化学发光底物用作酶的底物。
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