4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes
    9.
    发明申请
    4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes 有权
    4-甲基-2,3,5,9,9-五氮杂 - 环戊二烯并[a]萘

    公开(公告)号:US20140045857A1

    公开(公告)日:2014-02-13

    申请号:US13951531

    申请日:2013-07-26

    IPC分类号: C07D471/14

    CPC分类号: C07D487/14 C07D471/14

    摘要: The invention relates to 4-methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalene derivatives of general formula (I) which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.

    摘要翻译: 本发明涉及作为磷酸二酯酶2和/或10的抑制剂的通式(I)的4-甲基-2,3,5,9,9-五氮杂 - 环戊二烯并[a]萘衍生物,其可用于治疗中枢神经系统疾病 和其他疾病。 此外,本发明涉及制备药物组合物的方法以及制备本发明化合物的方法。