摘要:
Process for the production of oligonucleotides of formula II, in which the exocyclic amino groups of the bases adenine, guanine, cytosine, 7-deazaadenine and 7-deazaguanine carry N-phenylacetyl groups, are used for oligonucleotide synthesis, wherein in a first step a starting nucleotide is bound to a solid carrier, subsequently the desired oligonucleotide is synthesized by stepwise coupling with appropriately activated further monomeric nucleotide building blocks of the general formula I with the above-mentioned meanings, if desired, trivalent phosphorus is oxidized to pentavalent phosphorus during and after the synthesis, the oligonucleotide is cleaved from the carrier and the 5' protecting groups are cleaved off. The phenylacetyl functional groups that protect exocyclic NH.sub.2 groups of the bases can be cleaved off in a mild way with penicillin amidohydrolase (EC 3.5.1.11).
摘要:
Process for the production of oligonucleotides of formula II, in which the exocyclic amino groups of the bases adenine, guanine, cytosine, 7-deazaadenine and 7-deazaguanine carry N-phenylacetyl groups, are used for oligonucleotide synthesis, wherein in a first step a starting nucleotide is bound to a solid carrier, subsequently the desired oligonucleotide is synthesized by stepwise coupling with appropriately activated further monomeric nucleotide building blocks of the general formula I with the above-mentioned meanings, if desired, trivalent phosphorus is oxidized to pentavalent phosphorus during and after the synthesis, the oligonucleotide is cleaved from the carrier and the 5' protecting groups are cleaved off. The phenylacetyl functional groups that protect exocyclic NH.sub.2 groups of the bases can be cleaved off in a mild way with penicillin amidohydrolase (EC 3.5.1.11).
摘要:
Modular hold circuits which may be independently connected to a telephone line and powered therefrom are provided in accordance with the teachings of the present invention. Hold circuits connectable to a telephone line in the same manner as a telephone instrument are employed to detect an actuating signal generated at any telephone instrument in an off-hook condition connected to that telephone line. Upon detection of such actuating signal, an impedance is placed across the telphone line to establish a hold condition. The hold condition established may be released by placing any telephone instrument connected to a telephone line in an off-hook condition, however, if the telephone line is provided with a "call waiting" feature, such off-hook condition must be maintained for an interval exceeding that associated with a "call waiting" signal for the hold condition to be released.
摘要:
A method and apparatus for keypads, for conveying audible, visual or tactile information to a user regarding the identity, function, proper usage or potential utility of a given key or group of keys. The information being invoked by the user through superficial or proximal manipulation of the given key without having pressed or manipulated it in a way that would invoke its normal function. The primary concern of the system is as an informational adjunct to a more traditional keypad.
摘要:
An electrical apparatus, associated with a telecommunications line, includes a unique dual input/dual output prescribed audio actuating signal responsive circuit. The responsive circuit pursuant to a detection of the prescribed signal, in combination with a second signal pursuant to a detection by line pickup detection circuit of an off-hook condition of the telecommunications line, effecting production of an actuating output signal. The actuating signal upon suitable application, effecting an operational function of a suitably coupled associated electrical device. The associated device may be one of a number of electrical devices. In the preferred embodiment of the invention, this device is designated to be a time-day-date-stamp marker signal outputting device. The marker signal may then be recorded by a suitable recording device or, alternatively, not recorded but simply used as an audible time-day-date announcement clock.
摘要:
An abbreviated dialing apparatus especially suitable for cellular/mobile phone use, enabling a user to dial telephone numbers having repetitive digits without directly dialing all of the repetitive digits. The user, by executing a prescribed actuation of a prescribed key, such as the SEND key, can cause the system to complete an incomplete telephone number having repetitive finishing zeroes or other repetitive finishing digits, instead of directly dialing all of the repetitive digits. By determining whether a call is local or long distance, the apparatus determines the number of digits necessary to properly complete a telephone number and completes the number by filling in any missing finishing digits. Alternatively, the user by actuating a finish digit key or a finish zero key can cause the system to similarly fill in any missing finishing digits to complete an incomplete telephone number.
摘要:
Apparatus for eliminating the need to repeat dial the same area code on a given long distance call. The apparatus detects when a subscriber wishes to implement a long distance call. Upon detection of the start of a call, the apparatus automatically displays the last area code dialed. The subscriber if desiring the last area code merely dials seven digits. The apparatus recognizes that the subscriber has selected the last area code to cause the last area code dialed to be transmitted prior to the transmission of the seven digits thereby completing a telephone number. If the subscriber does not wish to utilize the last area code dialed he first dials a "1" and then dials in ten digits and the proper digits are transmitted with the area code digits being replaced in the area code storage memory. The apparatus is particularly adaptable for use by cellular subscribers due to the fact that it reduces the number of digits dialed, saves dialing time and is therefore inherently safer to utilize while operating a vehicle.
摘要:
An abbreviated dialing apparatus especially suitable for cellular/mobile phone use, enabling a user to dial telephone numbers having repetetive digits without directly dialing all of the repetetive digits. The user, by executing a prescribed actuation of a prescribed key, such as the SEND key, can cause the system to complete an incomplete telephone number having repetetive finishing zeroes or other repetetive finishing digits, instead of directly dialing all of the repetetive digits. By determining whether a call is local or long distance, the apparatus determines the number of digits necessary to properly complete a telephone number and completes the number by filling in any missing finishing digits. Alternatively, the user by actuating a finish digit key or a finish zero key can cause the system to similarly fill in any missing finishing digits to complete an incomplete telephone number.
摘要:
A selective call-forwarding method and apparatus utilizes telephone company facilities whereby a calling party will only be forwarded if a preferred calling code number is entered by the calling party. Upon receipt of a preferred calling code, a detector operates to detect and validate the code. Once the code is detected and validated, the apparatus proceeds to implement a connection to a third phone based on the automatic implementation of telephone company operating procedures to make the connection and, thereby, to selectively connect a preferred calling party to a remote telephone whereby the preferred party can communicate with the subscriber who has the procured service.
摘要:
A telephone answering apparatus has a forward drive time delay relay which causes a tape bearing a series of messages to advance for approximately 30 seconds subsequent to the reproduction of the last message in the series. The forward drive time delay relay cooperates with a recording amplifier so as to prevent recording of information on the advanced portion of the tape. The relay also cooperates with an erase circuit to cause recorded information on the advanced portion of tape to be erased to thereby create a no-signal or silent portions of tape. The advanced portions of the tape are detectable by a no-signal detector during rewind of the tape which automatically stops rewind when a no-signal portion is detected. A method is disclosed for generating silent portions on a tape and for automatically stopping rewind in a telephone answering apparatus at points, prior to complete rewind, where the no-signal portions are detected.