摘要:
There is provided a polypeptide that binds to syntaxin-1a and comprises the amino acid sequence shown in SEQ ID NO: 1 in the Sequence Listing, or a polypeptide having a homology of at least approximately 90% to the amino acid sequence that binds to syntaxin-1a, a partial peptide thereof, and a polynucleotide encoding any of these polypeptides or the complementary strand thereof, as well as an inhibitor, an antagonist, and an activator of physiological activity of any of the polypeptides. Further, a pharmaceutical composition that utilizes these is provided. There is also provided a method for producing the polypeptides or the peptide by genetic engineering techniques, a method for identifying the inhibitor, antagonist, or activator, and a method and a kit for diagnosing a disease with which the polypeptides are associated.
摘要翻译:提供了结合于syntaxin-1a并且包含序列表中SEQ ID NO:1所示的氨基酸序列的多肽,或与结合于语义蛋白的氨基酸序列具有至少约90%的同源性的多肽 -1a,其部分肽和编码这些多肽或其互补链中的任何一个的多核苷酸,以及任何多肽的抑制剂,拮抗剂和活化剂。 此外,提供利用这些的药物组合物。 还提供了通过基因工程技术生产多肽或肽的方法,用于鉴定抑制剂,拮抗剂或活化剂的方法,以及用于诊断与多肽相关的疾病的方法和试剂盒。
摘要:
An image processing apparatus has a line memory for writing and reading image data of one line. A write/read controller controls writing and reading the image data of one line in and from the line memory. A white line determiner determines whether an image corresponding to image data of one line being written in the line memory is a white line. An image processor performs specified image processing on the image data of one line read from the line memory by the write/read controller. An image processing controller generates an operation clock used in the image processor and causes the image processor to perform the specified image processing for the image data of one line determined not to be a white line and stops generating the operation clock and reads white data from a white data storage for the image data of one line determined to be a white line.
摘要:
A lubricating oil feeding structure that permits an adequate amount of lubricating oil to be fed to those parts around the transmission while avoiding an excess supply of lubricating oil to the lubricating oil passage in the shaft of the transmission. The transmission has a space (as a recess to hold the shaft therein) in which is arranged the oil guide part. The oil guide part has the bottomed cylinder, with its one end opened, the flange that flares outward at the open end of the bottomed cylinder, and the oil holes that communicate between the inside and the outside of the bottomed cylinder. The oil guide part is arranged in the space in such a way that the flange comes into contact with the outer race of the bearing.
摘要:
A wireless apparatus includes an antenna, a circuit board configured to form a wireless communication circuit that is connected to the antenna, and a housing configured to accommodate the circuit board and formed by resin molding. A linear conductor extends from a ground of the circuit board.
摘要:
A plurality of fluids are accurately and quickly mixed such that a target characteristic is attained. A fluid control device is provided with flow channels (5, 7, 11,13) for allowing a plurality of to-be-mixed fluids to flow; flow channels (15, 17) for allowing a mixed fluid to flow; a pump (19) for shifting the fluids in the flow channels; flow rate adjusting units (11b, 13b) for respectively adjusting flow rates of a plurality of to-be-mixed fluids; a measuring unit (15a) for optically measuring a characteristic of the mixed fluid; and a control unit (21) that controls the flow rate adjusting units (11b, 13b) to adjust the flow rates of the to-be-mixed fluids based on a result of the measurement of the measuring unit (15a), such that the mixed fluid attains a target characteristic.
摘要:
The present invention, the objects of which are to find out a gene encoding a protein having functions equivalent to those of G-protein-coupled receptor (GPCR) and the protein, and to provide a method for identifying a compound that regulates functions and/or expression of the protein, and to provide a useful mean for preventing and/or treating diseases related to the gene and the protein, provides a DNA comprising base sequence described in SEQ ID NO: 1 or complementary strand thereof, complementary strand of the DNA, a protein encoded by the DNA, a vector containing the DNA, a transformant containing the vector, an antibody against the protein, a method for identifying a compound that regulates functions and/or expression of the protein using aforementioned members, an agent for improving and a method for improving depression state, a pharmaceutical composition, and a reagent kit.
摘要翻译:本发明的目的是找出编码具有与G蛋白偶联受体(GPCR)和蛋白质相同功能的蛋白质的基因,并提供一种鉴定调节功能的化合物和/ 或蛋白质的表达,并且为预防和/或治疗与该基因和蛋白质相关的疾病提供有用的平均值,提供包含SEQ ID NO:1或其互补链中所述的碱基序列的DNA,DNA的互补链 ,由DNA编码的蛋白质,含有该载体的载体,含有该载体的转化子,针对该蛋白质的抗体,使用上述成员鉴定调节蛋白质的功能和/或表达的化合物的方法,改善剂 以及改善抑郁状态的方法,药物组合物和试剂盒。
摘要:
A disc device includes a casing, a disc processor, a drive motor, a transfer unit and a disc clamper. The transfer unit transfers an optical disc while holding the optical disc by driving the drive motor. The disc clamper switches a drive transmission of the drive unit in accordance with a holding condition of the optical disc with different diameters by the transfer unit to pivotally move the disc processor. The drive of the single drive motor effects both the transfer of the optical disc and the pivotal movement of the disc processor. A timing for transferring the optical disc and a timing for pivotally moving the disc processor can be suitably adjusted in accordance with the diameter of the optical disc.
摘要:
A ceramics sliding member for use in ultrapure water or pure water of the present invention is made of an SiC sintered body. The SiC sintered body includes β-SiC at a ratio of 20% or more thereto and has an average crystal structure whose aspect ratio is 2 or greater.