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公开(公告)号：US20170145365A1
公开(公告)日：2017-05-25
申请号：US15319905
申请日：2014-07-29
申请人： Hitachi, Ltd.
发明人： Takayuki NOZAKI , Masaharu KIYAMA , Masakazu SUGAYA , Guangbin ZHOU , Taku NAKAMURA , Daisuke SUZUKI , Shizu TAKEDA , Yumiko IGARASHI , Koichi TERADA
摘要： A culture which maintains an aseptic state at the time of culturing is achieved, the avoidance of damage to a closed-system culture vessel and of an influence to the cells due to impacts and oscillation is possible during transportation after being manufactured. The closed-system culture vessel 101 has culture vessels 201, 202 for maintaining the cells and/or the culture medium, and a culturing space which is closed by holding members 203, 204 for holding the culture vessels, and the holding member has a semi-open cavity 221 independent of the culturing space. Further, the holding member, by being provided with a lid fixing ring 220 surrounding a connector part 214, is not damaged even when impacts are applied during transportation.
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公开(公告)号：US20160017271A1
公开(公告)日：2016-01-21
申请号：US14770627
申请日：2013-03-25
申请人： HITACHI, LTD.
发明人： Takayuki NOZAKI , Guangbin ZHOU , Masaharu KIYAMA , Taku NAKAMURA , Shizu TAKEDA , Ryota NAKAJIMA , Masakazu SUGAYA , Koichi TERADA
摘要： In culture vessels for producing biological samples, it is possible to prevent decrease in a temperature at the time of taking out the culture vessels from an automatic culture apparatus and during delivery of the culture vessels which have been taken out from the automatic culture apparatus. This invention includes a culture vessel 201 holding a biological sample therein, a heat storage portion 701 holding the culture vessel, and a heat insulation portion 601 surrounding the heat storage portion. The whole circumference or a part of 609, 610, and 611 of the heat insulation portion 601 is removable depending on an arrangement environment.
摘要翻译： 在用于制造生物样品的培养容器中，可以防止从自动培养装置取出培养容器时的温度降低，以及从自动培养装置取出的培养容器的输送期间的温度降低。 本发明包括保存生物样品的培养容器201，保持培养容器的储热部701和围绕蓄热部的隔热部601。 隔热部分601的整个圆周或609,610和611的一部分可根据排列环境而被去除。
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3.发明申请公开(公告)号：US20200081015A1
公开(公告)日：2020-03-12
申请号：US16551780
申请日：2019-08-27
申请人： HITACHI, LTD.
发明人： Minoru SAKAIRI , Mayumi ABE , Taku NAKAMURA
IPC分类号： G01N33/68 , G01N30/72 , G01N33/493
摘要： A cancer screening processor includes a database which stores a sample information database storing information on a number of dispensed samples of urine sent from subjects; the sample dispensed for a cancer type which the subject desire a screening, a center selection unit which selects an analysis center C2 for each of cancer type to be analyzed by using a urinary tumor marker; the analysis center C2 receiving a sample container including dispensed sample on the basis of the cancer type and information from analysis centers, and a processing unit which counts a number of the sample containers on the basis of the sample information database, and performs a process step of sending the sample container to the analysis center when the number of the sample containers becomes equal to a number in the information from the analysis center.
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公开(公告)号：US20160108350A1
公开(公告)日：2016-04-21
申请号：US14894033
申请日：2013-08-23
申请人： HITACHI, LTD.
发明人： Masaharu KIYAMA , Guangbin ZHOU , Takayuki NOZAKI , Shizu MATSUOKA , Masakazu SUGAYA , Taku NAKAMURA , Koichi TERADA
摘要： The liquid feeder includes a liquid feeding pipe having a liquid introduce port and a liquid discharge port, a housing container which holds liquid to be introduced from the liquid introduce port, a liquid feed mechanism which feeds the liquid in the liquid feeding pipe to the liquid discharge port, a gas introduce unit which introduces gas into the liquid feeding pipe, and a liquid level detection unit which detects an advancing liquid level of the liquid to be fed in the liquid feeding pipe. The gas introduce unit is connected to a branch part provided in the liquid feeding pipe on the upstream side of the liquid feed mechanism. The liquid level detection unit is provided on the downstream side of the branch part.
摘要翻译： 液体供给器包括具有液体引入口和液体排出口的液体供给管，保持从液体引入口引入的液体的容纳容器，将液体供给管内的液体供给到液体的液体供给机构 排出口，将气体引入到液体供给管中的气体导入单元，以及液位检测单元，其检测供液管内供给液体的前进液面。 气体引入单元连接到设置在液体供给机构的上游侧的供液管中的分支部。 液位检测单元设置在分支部的下游侧。
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公开(公告)号：US20160002584A1
公开(公告)日：2016-01-07
申请号：US14768770
申请日：2013-03-15
申请人： HITACHI, LTD.
发明人： Takayuki NOZAKI , Guangbin ZHOU , Masaharu KIYAMA , Ryota NAKAJIMA , Shizu MATSUOKA , Taku NAKAMURA , Masakazu SUGAYA , Koichi TERADA
摘要： An automatic culture device which employs closed-system culture vessels and in which, when a passage part (2) and a rotational valve mechanism (3) are configured, the multiple culture vessels in a culture vessel part (1) can be rendered equal in liquid-feeding conditions by, for example, regulating the length of each passage. As a result, the evenness in quality of cells incubated in the multiple culture vessels is rendered possible. Furthermore, by providing a mechanism which enables a user to normally set passages in the device, the evenness in quality of the cells is rendered possible likewise.
摘要翻译： 一种采用封闭式培养容器的自动培养装置，其中，当构成通道部分（2）和旋转阀机构（3）时，培养容器部分（1）中的多个培养容器可以变得相等 通过例如调节每个通道的长度来进行送液条件。 结果，在多个培养容器中培养的细胞的质量的均匀性变得可能。 此外，通过提供使用户能够正常地设置设备中的通道的机构，同样地使得单元的质量的均匀性变得可能。
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公开(公告)号：US20190079071A1
公开(公告)日：2019-03-14
申请号：US15767244
申请日：2017-02-28
申请人： Hitachi, Ltd.
发明人： Minoru SAKAIRI , Masakazu SUGAYA , Koichi TERADA , Taku NAKAMURA , Norihito KUNO
IPC分类号： G01N33/493 , G01N33/574
摘要： A cancer analysis system includes, so as to perform an efficient image analysis in a cancer screening test using nematodes: a light source unit that irradiates a plate on which nematodes and a urine sample are plotted, from below; a photographing unit that takes an image of the plate irradiated by the light source unit; and an analyzer that analyzes the image taken by the photographing unit. The analyzer: couples a prescribed number of pixels in the image into a larger number of pixels thereof; and performs a chemotaxis assay of the nematodes based on a time variation of information on a luminous center of gravity of the image.
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公开(公告)号：US20180313839A1
公开(公告)日：2018-11-01
申请号：US15769682
申请日：2015-11-30
申请人： Hitachi, Ltd.
发明人： Minoru SAKAIRI , Masakazu SUGAYA , Koichi TERADA , Taku NAKAMURA , Norihito KUNO
IPC分类号： G01N33/574
CPC分类号： G01N33/48
摘要： In order to determine, in a cancer test using nematodes, whether or not the nematodes used in the cancer test are adequate, the present invention is characterized in that after a plate on which a urine from a subject and the nematode are set is placed, a cancer test apparatus performs imaging for quality assay of the nematode during the initial two minutes; an analysis apparatus determines a quality of the nematode using the imaging result; after taxis of the nematode is completed, the cancer test apparatus performs imaging for cancer test assay by the nematode; and the analysis apparatus determines the presence or absence of a cancer in the subject using the imaging result.
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公开(公告)号：US20170198249A1
公开(公告)日：2017-07-13
申请号：US15323977
申请日：2014-07-23
申请人： Hitachi, Ltd.
发明人： Masaharu KIYAMA , Guangbin ZHOU , Takayuki NOZAKI , Ryota NAKAJIMA , Daisuke SUZUKI , Yumiko IGARASHI , Shizu TAKEDA , Taku NAKAMURA , Masakazu SUGAYA , Koichi TERADA
摘要： There is the problem that a liquid culture medium fed by a pump has a high frequency of contact with a gas during movement in a tube, and the pH value of the liquid culture medium before and after feeding changes easily. In a liquid feeder and a cell culture apparatus provided therewith, a feed pipe 7 is connected with a gas bag 14, the liquid to be fed into the feed pipe 7 is fed so as to be sandwiched by a gas for suppressing the qualitative changes of the liquid. Furthermore, the gas bag is connected with a container 8 for holding a liquid, and holds the gas for suppressing qualitative changes of the liquid in a gas phase of the container.
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