-
公开(公告)号：US20170198249A1
公开(公告)日：2017-07-13
申请号：US15323977
申请日：2014-07-23
申请人： Hitachi, Ltd.
发明人： Masaharu KIYAMA , Guangbin ZHOU , Takayuki NOZAKI , Ryota NAKAJIMA , Daisuke SUZUKI , Yumiko IGARASHI , Shizu TAKEDA , Taku NAKAMURA , Masakazu SUGAYA , Koichi TERADA
摘要： There is the problem that a liquid culture medium fed by a pump has a high frequency of contact with a gas during movement in a tube, and the pH value of the liquid culture medium before and after feeding changes easily. In a liquid feeder and a cell culture apparatus provided therewith, a feed pipe 7 is connected with a gas bag 14, the liquid to be fed into the feed pipe 7 is fed so as to be sandwiched by a gas for suppressing the qualitative changes of the liquid. Furthermore, the gas bag is connected with a container 8 for holding a liquid, and holds the gas for suppressing qualitative changes of the liquid in a gas phase of the container.
-
公开(公告)号：US20170145365A1
公开(公告)日：2017-05-25
申请号：US15319905
申请日：2014-07-29
申请人： Hitachi, Ltd.
发明人： Takayuki NOZAKI , Masaharu KIYAMA , Masakazu SUGAYA , Guangbin ZHOU , Taku NAKAMURA , Daisuke SUZUKI , Shizu TAKEDA , Yumiko IGARASHI , Koichi TERADA
摘要： A culture which maintains an aseptic state at the time of culturing is achieved, the avoidance of damage to a closed-system culture vessel and of an influence to the cells due to impacts and oscillation is possible during transportation after being manufactured. The closed-system culture vessel 101 has culture vessels 201, 202 for maintaining the cells and/or the culture medium, and a culturing space which is closed by holding members 203, 204 for holding the culture vessels, and the holding member has a semi-open cavity 221 independent of the culturing space. Further, the holding member, by being provided with a lid fixing ring 220 surrounding a connector part 214, is not damaged even when impacts are applied during transportation.
-
公开(公告)号：US20220340847A1
公开(公告)日：2022-10-27
申请号：US17721233
申请日：2022-04-14
申请人： Hitachi, Ltd.
发明人： Takayuki NOZAKI , Kunio OHYAMA , Masaharu KIYAMA , Kakuro HIRAI
摘要： The present invention relates to an automatic culture device using a single-use closed system flow path for culturing a cell or a tissue, and realizes reduction in manufacturing cost and high integration property of a device. A cell culture system including an automatic culture device and an information processing device. The automatic culture device includes a plurality of types of closed system flow paths possible to be installed and removed, and a plurality of culture devices. The information processing device includes: an input device configured to receive, as an input, at least one piece of data selected from a group consisting of data of an identifier of a patient, data related to a transplantation method, data related to a type of cell, data related to the required number of cells, and data related to a treatment plan; an arithmetic device configured to select, based on the input data, from options of a cell culture method, the culture devices, and the closed system flow paths, the cell culture method, the culture device, and the closed system flow path to be used; and an output device configured to output a number of the closed system flow path to be used and a number of the culture device to be used.
-
公开(公告)号：US20160017271A1
公开(公告)日：2016-01-21
申请号：US14770627
申请日：2013-03-25
申请人： HITACHI, LTD.
发明人： Takayuki NOZAKI , Guangbin ZHOU , Masaharu KIYAMA , Taku NAKAMURA , Shizu TAKEDA , Ryota NAKAJIMA , Masakazu SUGAYA , Koichi TERADA
摘要： In culture vessels for producing biological samples, it is possible to prevent decrease in a temperature at the time of taking out the culture vessels from an automatic culture apparatus and during delivery of the culture vessels which have been taken out from the automatic culture apparatus. This invention includes a culture vessel 201 holding a biological sample therein, a heat storage portion 701 holding the culture vessel, and a heat insulation portion 601 surrounding the heat storage portion. The whole circumference or a part of 609, 610, and 611 of the heat insulation portion 601 is removable depending on an arrangement environment.
摘要翻译： 在用于制造生物样品的培养容器中，可以防止从自动培养装置取出培养容器时的温度降低，以及从自动培养装置取出的培养容器的输送期间的温度降低。 本发明包括保存生物样品的培养容器201，保持培养容器的储热部701和围绕蓄热部的隔热部601。 隔热部分601的整个圆周或609,610和611的一部分可根据排列环境而被去除。
-
5.发明公开公开(公告)号：US20230407228A1
公开(公告)日：2023-12-21
申请号：US18108527
申请日：2023-02-10
申请人： Hitachi, Ltd.
发明人： Takayuki NOZAKI , Yuki NIIMI , Masaharu KIYAMA , Kakuro HIRAI
摘要： A cell sheet cutting assistance system comprises a processor for executing a program and a storage device for storing the program. The processor: receives, as input, an evaluation standard of a cell sheet and quality information of a cultured cell sheet; determines whether the quality information satisfies the evaluation standard; and outputs a cutting position of the cell sheet based on a result of the determination.
-
公开(公告)号：US20170342365A1
公开(公告)日：2017-11-30
申请号：US15536673
申请日：2015-03-27
申请人： Hitachi, Ltd.
CPC分类号： C12M23/58 , C12M1/125 , C12M23/02 , C12M23/12 , C12M23/34 , C12M23/38 , C12M23/48 , C12M29/00 , C12M29/02 , C12M41/14 , C12M41/36 , C12M41/48 , C12M45/20
摘要： To provide a closed system culture vessel for realizing culturing in which an aseptic state is maintained at the time of culturing, and making the reduction of the shear stress generated during conveyance after manufacturing possible. A closed system culture vessel 201 holds a second vessel 302 consisting of an insert vessel on the inside of a first vessel 301, and a lid portion 303 of the closed system culture vessel 201 forms a closed space with the first vessel 301 and has a convex portion 305 contacting the entire outer circumference of the second vessel 302. During conveyance, the closed system culture vessel is conveyed in a state in which the culture medium for conveyance is filled within the second vessel 302.
-
公开(公告)号：US20160108350A1
公开(公告)日：2016-04-21
申请号：US14894033
申请日：2013-08-23
申请人： HITACHI, LTD.
发明人： Masaharu KIYAMA , Guangbin ZHOU , Takayuki NOZAKI , Shizu MATSUOKA , Masakazu SUGAYA , Taku NAKAMURA , Koichi TERADA
摘要： The liquid feeder includes a liquid feeding pipe having a liquid introduce port and a liquid discharge port, a housing container which holds liquid to be introduced from the liquid introduce port, a liquid feed mechanism which feeds the liquid in the liquid feeding pipe to the liquid discharge port, a gas introduce unit which introduces gas into the liquid feeding pipe, and a liquid level detection unit which detects an advancing liquid level of the liquid to be fed in the liquid feeding pipe. The gas introduce unit is connected to a branch part provided in the liquid feeding pipe on the upstream side of the liquid feed mechanism. The liquid level detection unit is provided on the downstream side of the branch part.
摘要翻译： 液体供给器包括具有液体引入口和液体排出口的液体供给管，保持从液体引入口引入的液体的容纳容器，将液体供给管内的液体供给到液体的液体供给机构 排出口，将气体引入到液体供给管中的气体导入单元，以及液位检测单元，其检测供液管内供给液体的前进液面。 气体引入单元连接到设置在液体供给机构的上游侧的供液管中的分支部。 液位检测单元设置在分支部的下游侧。
-
公开(公告)号：US20160002584A1
公开(公告)日：2016-01-07
申请号：US14768770
申请日：2013-03-15
申请人： HITACHI, LTD.
发明人： Takayuki NOZAKI , Guangbin ZHOU , Masaharu KIYAMA , Ryota NAKAJIMA , Shizu MATSUOKA , Taku NAKAMURA , Masakazu SUGAYA , Koichi TERADA
摘要： An automatic culture device which employs closed-system culture vessels and in which, when a passage part (2) and a rotational valve mechanism (3) are configured, the multiple culture vessels in a culture vessel part (1) can be rendered equal in liquid-feeding conditions by, for example, regulating the length of each passage. As a result, the evenness in quality of cells incubated in the multiple culture vessels is rendered possible. Furthermore, by providing a mechanism which enables a user to normally set passages in the device, the evenness in quality of the cells is rendered possible likewise.
摘要翻译： 一种采用封闭式培养容器的自动培养装置，其中，当构成通道部分（2）和旋转阀机构（3）时，培养容器部分（1）中的多个培养容器可以变得相等 通过例如调节每个通道的长度来进行送液条件。 结果，在多个培养容器中培养的细胞的质量的均匀性变得可能。 此外，通过提供使用户能够正常地设置设备中的通道的机构，同样地使得单元的质量的均匀性变得可能。
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.029 秒)
