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42 条记录 (耗时 0.033 秒)

    Adhesive and laminate
    1.
    发明授权
    Adhesive and laminate 有权
    粘合剂和层压材料

    公开(公告)号：US07754235B2

    公开(公告)日：2010-07-13

    申请号：US11410003

    申请日：2006-04-25

    申请人： Hitoshi Akemi ,  Keigo Inosaka ,  Junichi Sekiya ,  Junichi Saito ,  Yoshifumi Hosaka

    发明人： Hitoshi Akemi ,  Keigo Inosaka ,  Junichi Sekiya ,  Junichi Saito ,  Yoshifumi Hosaka

    IPC分类号： A61F13/02 ,  B32B27/30 ,  C09D5/02

    CPC分类号： C09J133/14 ,  Y10T428/2891 ,  Y10T428/31935

    摘要： The present invention provides an adhesive capable of affording an adhesive layer showing reduced stickiness, reduced cohesive failure and the like. An adhesive containing a copolymer obtained by copolymerizing monomers containing a (meth)acrylic acid alkyl ester as a main component, and a vinyl monomer having a hydroxyl group and/or a carboxyl group and which has an average molecular radius of not less than 70 nm as measured by a multi angle laser light scattering method.

    摘要翻译： 本发明提供能够提供粘合剂层的粘合剂，粘合剂层显示出降低的粘性，减少的内聚破坏等。 含有通过使包含（甲基）丙烯酸烷基酯作为主要成分的单体和具有羟基和/或羧基的乙烯基单体共聚而得到的平均分子半径不小于70nm的共聚物 通过多角度激光散射法测量。

    Adhesive and laminate
    2.
    发明申请
    Adhesive and laminate 有权
    粘合剂和层压材料

    公开(公告)号：US20060246281A1

    公开(公告)日：2006-11-02

    申请号：US11410003

    申请日：2006-04-25

    申请人： Hitoshi Akemi ,  Keigo Inosaka ,  Junichi Sekiya ,  Junichi Saito ,  Yoshifumi Hosaka

    发明人： Hitoshi Akemi ,  Keigo Inosaka ,  Junichi Sekiya ,  Junichi Saito ,  Yoshifumi Hosaka

    IPC分类号： C09D5/02 ,  B32B27/30

    CPC分类号： C09J133/14 ,  Y10T428/2891 ,  Y10T428/31935

    摘要： The present invention provides an adhesive capable of affording an adhesive layer showing reduced stickiness, reduced cohesive failure and the like. An adhesive containing a copolymer obtained by copolymerizing monomers containing a (meth)acrylic acid alkyl ester as a main component, and a vinyl monomer having a hydroxyl group and/or a carboxyl group and which has an average molecular radius of not less than 70 nm as measured by a multi angle laser light scattering method.

    摘要翻译： 本发明提供能够提供粘合剂层的粘合剂，粘合剂层显示出降低的粘性，减少的内聚破坏等。 含有通过使包含（甲基）丙烯酸烷基酯作为主要成分的单体和具有羟基和/或羧基的乙烯基单体共聚而得到的平均分子半径不小于70nm的共聚物 通过多角度激光散射法测量。

    High molecular-weight medical adhesive with plasticizers, and product thereof
    3.
    发明授权
    High molecular-weight medical adhesive with plasticizers, and product thereof 失效
    具有增塑剂的高分子量医用胶及其制品

    公开(公告)号：US06231883B1

    公开(公告)日：2001-05-15

    申请号：US09117000

    申请日：1998-07-17

    申请人： Keigo Inosaka ,  Takateru Muraoka ,  Hitoshi Akemi ,  Saburo Otsuka ,  Yuichi Inoue

    发明人： Keigo Inosaka ,  Takateru Muraoka ,  Hitoshi Akemi ,  Saburo Otsuka ,  Yuichi Inoue

    IPC分类号： A61L1524

    CPC分类号： A61L15/58

    摘要： A medical adhesive sheet comprising a support and an adhesive layer formed on one side of said support, wherein the adhesive layer comprises an adhesive polymer having a weight average molecular weight of not less than 2,000,000, preferably not less than 2,500,000, and at least one plasticizer compatible with said polymer. The medical adhesive sheet of the present invention simultaneously satisfies the adhesive property to the skin and low irritation property, since it can retain the plasticizer in the adhesive layer, even without a crosslinking treatment. The effects of the present invention can be exerted irrespective of the kind of functional group that the plasticizer and drug have.

    摘要翻译： 一种医用粘合片，其包含支撑体和形成在所述支撑体的一侧上的粘合剂层，其中所述粘合剂层包含重均分子量不小于2,000,000，优选不小于2,500,000的粘合剂聚合物，以及至少一种增塑剂 与所述聚合物相容。 本发明的医用粘合片同时满足与皮肤的粘合性和低刺激性，因为即使不进行交联处理也能够将增塑剂保留在粘合剂层中。 无论增塑剂和药物具有的官能团的种类如何，都可以发挥本发明的效果。

    Medical adhesive composition, medical adhesive tape using the same and tape preparation for percutaneous absorption
    4.
    发明授权
    Medical adhesive composition, medical adhesive tape using the same and tape preparation for percutaneous absorption 失效

    公开(公告)号：US07056526B2

    公开(公告)日：2006-06-06

    申请号：US10230495

    申请日：2002-08-29

    申请人： Hidetoshi Kuroda ,  Takateru Muraoka ,  Keigo Inosaka ,  Hitoshi Akemi

    发明人： Hidetoshi Kuroda ,  Takateru Muraoka ,  Keigo Inosaka ,  Hitoshi Akemi

    IPC分类号： A61K9/70

    CPC分类号： A61K9/7061 ,  A61L15/58 ,  Y10T428/28 ,  C08L39/06

    摘要： The present invention provides a medical adhesive tape and a tape preparation for percutaneous absorption, both having an adhesive layer that resists glue remainder and stickiness upon peeling off of the tape even after adhesion to the human skin for a long time, and a medical adhesive composition to be used for such tapes. The medical adhesive composition of the present invention includes, as essential elements, (A) a copolymer containing (a) alkyl (meth)acrylate, wherein the alkyl moiety has 4 to 18 carbon atoms, in a proportion of not less than 50 wt % of the copolymer and (b) a carboxyl group-containing vinyl compound in a proportion of 0.1 wt %–10 wt % of the copolymer, (B) an alkoxide or a chelate compound of at least a metal selected from titanium, zirconium, zinc and aluminum, and (C) a polyol compound in a proportion of 0.2 wt %–5 wt % of the aforementioned medical adhesive composition. The medical adhesive tape of the present invention and tape preparation for percutaneous absorption are characterized in that the adhesive layer contains the above-mentioned medical adhesive composition of the present invention.

    Percutaneous absorption preparation
    5.
    发明授权
    Percutaneous absorption preparation 有权
    经皮吸收制剂

    公开(公告)号：US6132761A

    公开(公告)日：2000-10-17

    申请号：US146666

    申请日：1998-09-03

    申请人： Takateru Muraoka ,  Hitoshi Akemi ,  Keigo Inosaka ,  Hiroko Ishitani ,  Saburo Otsuka

    发明人： Takateru Muraoka ,  Hitoshi Akemi ,  Keigo Inosaka ,  Hiroko Ishitani ,  Saburo Otsuka

    IPC分类号： A61K9/70 ,  A61K47/14 ,  A61K47/22 ,  A61F13/02

    CPC分类号： A61K9/7053 ,  A61K47/14 ,  A61K47/22 ,  A61K9/0014 ,  A61K9/7061

    摘要： The present invention provides a percutaneous absorption preparation which hardly causes the coloration phenomenon and is excellent in the stability of the drug content. The percutaneous absorption preparation comprises a support and a pressure-sensitive adhesive layer formed on at least one side of the support, wherein the pressure-sensitive adhesive layer contains a percutaneous absorptive drug and at least one of 2-mercaptobenzimidazole and propyl gallate, with the proviso that the percutaneous absorptive drug is not 6-amino-5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)benzimidazole and pharmacologically acceptable salt thereof.

    摘要翻译： 本发明提供一种几乎不引起着色现象并且药物含量稳定性优异的经皮吸收制剂。 经皮吸收制剂包括载体和形成在载体的至少一侧上的压敏粘合剂层，其中压敏粘合剂层含有经皮吸收药物和2-巯基苯并咪唑和没食子酸丙酯中的至少一种，其中 条件是经皮吸收药物不是6-氨基-5-氯-1-异丙基-2-（4-甲基-1-哌嗪基）苯并咪唑及其药理学上可接受的盐。

    Adhesive preparation containing fentanyl
    8.
    发明授权
    Adhesive preparation containing fentanyl 有权
    含芬太尼的粘合剂

    公开(公告)号：US08591939B2

    公开(公告)日：2013-11-26

    申请号：US11196935

    申请日：2005-08-04

    申请人： Yuji Saeki ,  Masato Nishimura ,  Kensuke Matsuoka ,  Takateru Muraoka ,  Yoshifumi Hosaka ,  Mitsuhiko Hori ,  Kazuhisa Ninomiya ,  Hitoshi Akemi ,  Hidetoshi Kuroda

    发明人： Yuji Saeki ,  Masato Nishimura ,  Kensuke Matsuoka ,  Takateru Muraoka ,  Yoshifumi Hosaka ,  Mitsuhiko Hori ,  Kazuhisa Ninomiya ,  Hitoshi Akemi ,  Hidetoshi Kuroda

    IPC分类号： A61K31/445 ,  A61F13/02

    CPC分类号： A61K9/7053 ,  A61K31/4468

    摘要： The present invention provides a Fentanyl-containing percutaneously absorbable adhesive preparation, which is obtained from economic starting materials, has a constitution simpler than that of conventional ones, has sufficient skin permeability, and which permits control of skin permeability by changing the mixing ratio of two kinds of polyisobutylene having different molecular weights, a tackifier and an organic liquid. Specifically, the present invention provides a percutaneously absorbable adhesive preparation comprising a support and an adhesive layer laminated on one surface thereof, wherein the adhesive layer comprises Fentanyl, two kinds of polyisobutylene having different molecular weights, a tackifier and an organic liquid compatible with the aforementioned two kinds of polyisobutylene and the aforementioned tackifier.

    摘要翻译： 本发明提供了一种经济起始材料得到的含有芬太尼的经皮吸收性粘合剂制剂，其结构比以往更简单，具有足够的皮肤渗透性，并且通过改变两者的混合比可以控制皮肤渗透性 种类具有不同分子量的聚异丁烯，增粘剂和有机液体。 具体地说，本发明提供了一种经皮吸收性粘合剂制剂，其包含在其一个表面上层叠的载体和粘合剂层，其中所述粘合剂层包括芬太尼，两种具有不同分子量的聚异丁烯，增粘剂和与上述相容的有机液体 两种聚异丁烯和上述增粘剂。