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公开(公告)号:US12065460B2
公开(公告)日:2024-08-20
申请号:US18505877
申请日:2023-11-09
Applicant: Hongene Biotech Corporation
Inventor: Gaomai Yang , Yun-Chiao Yao , David Yu , Aldrich N. K. Lau
IPC: C07H1/00 , C07H21/00 , C08F120/68 , C08F220/28 , C08F220/56 , C08F265/10
CPC classification number: C07H1/00 , C07H21/00 , C08F120/68 , C08F220/286 , C08F220/56 , C08F265/10
Abstract: Embodiments of the present application relate to polymers used as polymeric polyvalent hub for liquid phase oligonucleotide synthesis. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis using the polyvalent hub are also provided.
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公开(公告)号:US20230212209A1
公开(公告)日:2023-07-06
申请号:US18146279
申请日:2022-12-23
Applicant: Hongene Biotech Corporation
Inventor: Gaomai Yang , Yun-Chiao Yao , David Yu , Aldrich N.K. Lau
IPC: C07H1/00 , C08F220/56 , C07H21/00 , C08F265/10 , C08F220/28 , C08F120/68
CPC classification number: C07H1/00 , C08F220/56 , C07H21/00 , C08F265/10 , C08F220/286 , C08F120/68
Abstract: Embodiments of the present application relate to polymers used as polymeric polyvalent hub for liquid phase oligonucleotide synthesis. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis using the polyvalent hub are also provided.
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公开(公告)号:US20240002420A1
公开(公告)日:2024-01-04
申请号:US18337233
申请日:2023-06-19
Applicant: Hongene Biotech Corporation
Inventor: Gaomai Yang , Jingshe Song , Shengdong Wang , Yun-Chiao Yao , Hongrong Yang , David Yu , Aldrich N.K. Lau
IPC: C07H1/00 , C08F120/68 , C08F220/28 , C08F220/56 , C08F265/10
CPC classification number: C07H1/00 , C08F120/68 , C08F220/286 , C08F220/56 , C08F265/10
Abstract: Embodiments of the present application relate to polymers used as polymeric polyvalent hubs for liquid phase oligonucleotide synthesis. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis using the polymers are also provided.
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公开(公告)号:US11851454B2
公开(公告)日:2023-12-26
申请号:US18146279
申请日:2022-12-23
Applicant: Hongene Biotech Corporation
Inventor: Gaomai Yang , Yun-Chiao Yao , David Yu , Aldrich N. K. Lau
IPC: C07H1/00 , C07H21/00 , C08F220/56 , C08F265/10 , C08F220/28 , C08F120/68
CPC classification number: C07H1/00 , C07H21/00 , C08F120/68 , C08F220/286 , C08F220/56 , C08F265/10
Abstract: Embodiments of the present application relate to polymers used as polymeric polyvalent hub for liquid phase oligonucleotide synthesis. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis using the polyvalent hub are also provided.
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公开(公告)号:US12134630B2
公开(公告)日:2024-11-05
申请号:US18337233
申请日:2023-06-19
Applicant: Hongene Biotech Corporation
Inventor: Gaomai Yang , Jingshe Song , Shengdong Wang , Yun-Chiao Yao , Hongrong Yang , David Yu , Aldrich N.K. Lau
IPC: C07H1/00 , C08F120/68 , C08F220/28 , C08F220/56 , C08F265/10
Abstract: Embodiments of the present application relate to polymers used as polymeric polyvalent hubs for liquid phase oligonucleotide synthesis. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis using the polymers are also provided.
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公开(公告)号:US20250034192A1
公开(公告)日:2025-01-30
申请号:US18902678
申请日:2024-09-30
Applicant: Hongene Biotech Corporation
Inventor: Gaomai Yang , Jingshe Song , Shengdong Wang , Yun-Chiao Yao , Hongrong Yang , David Yu , Aldrich N.K. Lau
IPC: C07H1/00 , C08F120/68 , C08F220/28 , C08F220/56 , C08F265/10
Abstract: Embodiments of the present application relate to polymers used as polymeric polyvalent hubs for liquid phase oligonucleotide synthesis. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis using the polymers are also provided.
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公开(公告)号:US12180140B2
公开(公告)日:2024-12-31
申请号:US18390545
申请日:2023-12-20
Applicant: Hongene Biotech Corporation
Inventor: Gaomai Yang , Min Xie , Hongrong Yang , Shengdong Wang , Aldrich N. K. Lau , Ruiming Zou , David Yu
IPC: C07C237/22 , C07C231/00 , C07C233/59 , C07H1/00 , C07H21/00
Abstract: The present disclosure relates to methods and compounds for liquid phase oligonucleotide synthesis employing the use of small molecules with lipophilic groups. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis using the compounds described herein are also provided.
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公开(公告)号:US20240092817A1
公开(公告)日:2024-03-21
申请号:US18505877
申请日:2023-11-09
Applicant: Hongene Biotech Corporation
Inventor: Gaomai Yang , Yun-Chiao Yao , David Yu , Aldrich N.K. Lau
IPC: C07H1/00 , C07H21/00 , C08F120/68 , C08F220/28 , C08F220/56 , C08F265/10
CPC classification number: C07H1/00 , C07H21/00 , C08F120/68 , C08F220/286 , C08F220/56 , C08F265/10
Abstract: Embodiments of the present application relate to polymers used as polymeric polyvalent hub for liquid phase oligonucleotide synthesis. Methods for making an oligonucleotide by liquid phase oligonucleotide synthesis using the polyvalent hub are also provided.
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