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公开(公告)号：US07645987B2
公开(公告)日：2010-01-12
申请号：US11234051
申请日：2005-09-22
Applicant: Huan-Cheng Chang , Chung-Hsuan Chen
Inventor： Huan-Cheng Chang , Chung-Hsuan Chen
CPC classification number: H01J49/16 , H01J49/0454
Abstract: A method for producing gas phase molecules includes providing a sample of molecules, the sample being characterized by a charge distribution, and directing acoustic radiation at the sample of molecules to desorb at least some of the molecules from the sample such that the desorbed molecules have a charge distribution that is substantially the same as the charge distribution of the sample of molecules.
Abstract translation: 一种生产气相分子的方法包括提供分子样品，该样品的特征在于电荷分布，并引导分子样品上的声辐射以从样品解吸至少一些分子，使得解吸的分子具有 电荷分布基本上与分子样品的电荷分布相同。
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公开(公告)号：US20070131871A1
公开(公告)日：2007-06-14
申请号：US11234051
申请日：2005-09-22
Applicant: Huan-Cheng Chang , Chung-Hsuan Chen
Inventor： Huan-Cheng Chang , Chung-Hsuan Chen
IPC: H01J27/00
CPC classification number: H01J49/16 , H01J49/0454
Abstract: A method for producing gas phase molecules includes providing a sample of molecules, the sample being characterized by a charge distribution, and directing acoustic radiation at the sample of molecules to desorb at least some of the molecules from the sample such that the desorbed molecules have a charge distribution that is substantially the same as the charge distribution of the sample of molecules.
Abstract translation: 一种生产气相分子的方法包括提供分子样品，该样品的特征在于电荷分布，并引导分子样品上的声辐射以从样品解吸至少一些分子，使得解吸的分子具有 电荷分布基本上与分子样品的电荷分布相同。
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公开(公告)号：US07119331B2
公开(公告)日：2006-10-10
申请号：US10726071
申请日：2003-12-01
Applicant: Huan-Cheng Chang , Wen-Ping Peng , Yong Cai
Inventor： Huan-Cheng Chang , Wen-Ping Peng , Yong Cai
IPC: B01D59/44
CPC classification number: H01J49/424 , G01N21/6402 , G01N21/6428 , G01N2021/6419 , G01N2021/6441
Abstract: A nanoparticle ion detector includes an ion trap that receives charged particles ejected from a mass selection device. A laser beam illuminates the particles to induce fluorescence, which is detected by the photon detector. Particles are periodically dumped from the ion trap. A mass spectrum of the charged particles can be obtained by comparing signals from the photon detector with the particle ejection characteristics of the mass selection device.
Abstract translation: 纳米颗粒离子检测器包括接收从质量选择装置喷射的带电粒子的离子阱。 激光束照射颗粒以诱导荧光，其由光子检测器检测。 颗粒定期从离子阱中倾倒出来。 通过将来自光子检测器的信号与质量选择装置的粒子喷射特性进行比较，可以获得带电粒子的质谱。
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公开(公告)号：US07161147B1
公开(公告)日：2007-01-09
申请号：US11134616
申请日：2005-05-20
Applicant: Huan-Cheng Chang , Joseph W. Ting
Inventor： Huan-Cheng Chang , Joseph W. Ting
CPC classification number: H01J49/0027
Abstract: A method for identifying a biological organism that includes providing a biological sample corresponding to the biological organism, ionizing the biological sample to produce an ionized sample of the biological sample, performing a mass spectrometry analysis of the ionized sample, and identifying the biological organism in accordance with the mass spectrometry analysis.
Abstract translation: 一种用于识别生物体的方法，包括提供对应于所述生物体的生物样品，电离所述生物样品以产生所述生物样品的离子化样品，对所述离子化样品进行质谱分析，以及根据 通过质谱分析。
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公开(公告)号：US08168413B2
公开(公告)日：2012-05-01
申请号：US11939311
申请日：2007-11-13
Applicant: Huan-Cheng Chang , Wunshain Fann , Chau-Chung Han
Inventor： Huan-Cheng Chang , Wunshain Fann , Chau-Chung Han
CPC classification number: C09K11/65 , C01B32/28 , Y10T428/2982
Abstract: A method for preparing luminescent diamond particles (e.g., fluorescent nanodiamonds). The method includes irradiating diamond particles with an ion beam and heating the irradiated diamond particles in a non-oxidizing atmosphere at a temperature between 600 and 1000° C. The diamond particles have a diameter of 1 nm to 1 mm and the ion beam has a kinetic energy of 1 KeV to 900 MeV. Also disclosed are luminescent diamond particles prepared by this method and methods of using them.
Abstract translation: 制备发光金刚石颗粒（例如荧光纳米金刚石）的方法。 该方法包括用离子束照射金刚石颗粒并在600-1000℃的温度下在非氧化性气氛中加热照射的金刚石颗粒。金刚石颗粒的直径为1nm至1mm，离子束具有 1 KeV至900 MeV的动能。 还公开了通过该方法制备的发光金刚石颗粒和使用它们的方法。
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Patent Agency Ranking
公开(公告)号：US20060284074A1
公开(公告)日：2006-12-21
申请号：US11134616
申请日：2005-05-20
Applicant: Huan-Cheng Chang , Joseph Ting
Inventor： Huan-Cheng Chang , Joseph Ting
IPC: H01J49/00
CPC classification number: H01J49/0027
Abstract: A method for identifying a biological organism that includes providing a biological sample corresponding to the biological organism, ionizing the biological sample to produce an ionized sample of the biological sample, performing a mass spectrometry analysis of the ionized sample, and identifying the biological organism in accordance with the mass spectrometry analysis.
Abstract translation: 一种用于识别生物体的方法，包括提供对应于所述生物体的生物样品，电离所述生物样品以产生所述生物样品的离子化样品，对所述离子化样品进行质谱分析，以及根据 通过质谱分析。
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公开(公告)号：US20060154304A1
公开(公告)日：2006-07-13
申请号：US11361269
申请日：2006-02-23
Applicant: Chau-Chung Han , Huan-Cheng Chang , Sheng-Chung Lee , Wei-Hao Chen
Inventor： Chau-Chung Han , Huan-Cheng Chang , Sheng-Chung Lee , Wei-Hao Chen
CPC classification number: G01N33/551 , Y10S977/705 , Y10S977/904
Abstract: A method for profiling proteins in a biological sample by mixing the sample and a diamond-based composition. The diamond-based composition includes a diamond crystallite having a surface that contains chemically derivatized surface groups and a polymer having a plurality of functional groups non-covalently bound to the surface groups. Proteins in the sample are mixed with and allowed to bind to the diamond-based composition. The bound proteins are then profiled.
Abstract translation: 通过混合样品和基于金刚石的组合物来分析生物样品中的蛋白质的方法。 基于金刚石的组合物包括具有包含化学衍生化表面基团的表面的金刚石微晶和具有多个与表面基团非共价结合的官能团的聚合物。 将样品中的蛋白与基于金刚石的组合物混合并与其结合。 然后将结合的蛋白质分析。
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公开(公告)号：US20080118966A1
公开(公告)日：2008-05-22
申请号：US11939311
申请日：2007-11-13
Applicant: Huan-Cheng Chang , Wunshain Fann , Chau-Chung Han
Inventor： Huan-Cheng Chang , Wunshain Fann , Chau-Chung Han
CPC classification number: C09K11/65 , C01B32/28 , Y10T428/2982
Abstract: A method for preparing luminescent diamond particles (e.g., fluorescent nanodiamonds). The method includes irradiating diamond particles with an ion beam and heating the irradiated diamond particles in a non-oxidizing atmosphere at a temperature between 600 and 1000° C. The diamond particles have a diameter of 1 nm to 1 mm and the ion beam has a kinetic energy of 1 KeV to 900 MeV. Also disclosed are luminescent diamond particles prepared by this method and methods of using them.
Abstract translation: 制备发光金刚石颗粒（例如荧光纳米金刚石）的方法。 该方法包括用离子束照射金刚石颗粒并在600-1000℃的温度下在非氧化性气氛中加热照射的金刚石颗粒。金刚石颗粒的直径为1nm至1mm，离子束具有 1 KeV至900 MeV的动能。 还公开了通过该方法制备的发光金刚石颗粒和使用它们的方法。
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公开(公告)号：US07326837B2
公开(公告)日：2008-02-05
申请号：US11361269
申请日：2006-02-23
Applicant: Chau-Chung Han , Huan-Cheng Chang , Sheng-Chung Lee , Wei-Hao Chen
Inventor： Chau-Chung Han , Huan-Cheng Chang , Sheng-Chung Lee , Wei-Hao Chen
IPC: G01N33/00
CPC classification number: G01N33/551 , Y10S977/705 , Y10S977/904
Abstract: A method for profiling proteins in a biological sample by mixing the sample and a diamond-based composition. The diamond-based composition includes a diamond crystallite having a surface that contains chemically derivatized surface groups and a polymer having a plurality of functional groups non-covalently bound to the surface groups. Proteins in the sample are mixed with and allowed to bind to the diamond-based composition. The bound proteins are then profiled.
Abstract translation: 通过混合样品和基于金刚石的组合物来分析生物样品中的蛋白质的方法。 基于金刚石的组合物包括具有包含化学衍生化表面基团的表面的金刚石微晶和具有多个与表面基团非共价结合的官能团的聚合物。 将样品中的蛋白与基于金刚石的组合物混合并与其结合。 然后将结合的蛋白质分析。
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公开(公告)号：US20060154259A1
公开(公告)日：2006-07-13
申请号：US11031601
申请日：2005-01-07
Applicant: Huan-Cheng Chang , Chau-Chung Han
Inventor： Huan-Cheng Chang , Chau-Chung Han
CPC classification number: G01N33/551
Abstract: A diamond-based composition that contains (1) a diamond crystallite having chemically derivatized surface groups, and (2) a polymer having functional groups, in which a portion of the functional groups bind to the chemically derivatized surface groups non-covalently. Also disclosed are methods of using such composition for analyzing a biological sample by determining the identity of biomolecules bound to the composition.
Abstract translation: 一种基于金刚石的组合物，其包含（1）具有化学衍生的表面基团的金刚石微晶，和（2）具有官能团的聚合物，其中一部分官能团非共价结合化学衍生的表面基团。 还公开了通过确定与组合物结合的生物分子的身份来使用这种组合物来分析生物样品的方法。
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