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    SYSTEM FOR IMPROVING CARDIAC FUNCTION BY SEALING A PARTITIONING MEMBRANE WITHIN A VENTRICLE
    2.
    发明申请
    SYSTEM FOR IMPROVING CARDIAC FUNCTION BY SEALING A PARTITIONING MEMBRANE WITHIN A VENTRICLE 有权
    通过密封隔离膜在心脏中改善心脏功能的系统

    公开(公告)号：US20090254195A1

    公开(公告)日：2009-10-08

    申请号：US12422144

    申请日：2009-04-10

    申请人： Alexander Khairkhahan ,  Serjan D. Nikolic ,  Hugh R. Sharkey

    发明人： Alexander Khairkhahan ,  Serjan D. Nikolic ,  Hugh R. Sharkey

    IPC分类号： A61F2/04

    CPC分类号： A61F2/2487 ,  A61B17/0057 ,  A61B17/12022 ,  A61B17/12122 ,  A61B17/1214 ,  A61B17/12172 ,  A61B17/12195 ,  A61B2017/00243 ,  A61B2017/00557 ,  A61B2017/00575 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/00601 ,  A61B2017/00615 ,  A61B2017/00632 ,  A61B2017/00867 ,  A61B2017/0649 ,  A61B2017/12095

    摘要： Partitioning devices that may be secured and sealed within a heart chamber for separating a patient's heart chamber into a productive portion and a non-productive portion are described herein. The partitioning devices described herein may include a reinforced membrane with outwardly biased members. The reinforced membrane may have a central hub with a distally extending support stem with a plurality of feet which extend radially from a centerline axis and preferably have ends that are aligned in a common plane. These devices may be secured within the heart chamber by sealing them to the wall of the heart chamber, for example, by inflating an inflatable element on the periphery of the device. The non-productive portion may be filled with a material, including occlusive materials. Sealing and/or filling the non-productive portion formed by the devices described herein may help prevent leakage from the non-productive region. Also described herein are systems including these devices and methods of using them, which may be suitable for treating patients with heart disease, particularly congestive heart failure.

    摘要翻译： 本文描述了可以在心室内固定和密封以将患者的心室分离成生产部分和非生产性部分的分隔装置。 本文所述的分隔装置可以包括具有向外偏置构件的增强膜。 增强膜可以具有中心毂，其具有远端延伸的支撑杆，其具有从中心线轴线径向延伸的多个脚，并且优选地具有在公共平面中对准的端部。 这些装置可以通过将它们密封到心室的壁来固定在心脏腔室内，例如通过使装置的周边上的可充气元件膨胀。 非生产性部分可以填充材料，包括封闭材料。 密封和/或填充由本文所述的装置形成的非生产性部分可以有助于防止从非生产性区域泄漏。 本文还描述了包括这些装置和使用它们的方法的系统，其可适用于治疗心脏病患者，特别是充血性心力衰竭。

    Peripheral seal for a ventricular partitioning device
    3.
    发明授权
    Peripheral seal for a ventricular partitioning device 有权
    心室分隔装置的外围密封

    公开(公告)号：US07582051B2

    公开(公告)日：2009-09-01

    申请号：US11151164

    申请日：2005-06-10

    申请人： Alexander Khairkhahan ,  Hugh R. Sharkey ,  Serjan D. Nikolic ,  Branislav Radovancevic

    发明人： Alexander Khairkhahan ,  Hugh R. Sharkey ,  Serjan D. Nikolic ,  Branislav Radovancevic

    IPC分类号： A61F2/00

    CPC分类号： A61B17/12022 ,  A61B17/12122 ,  A61B17/12172 ,  A61B17/1219 ,  A61B2017/00243 ,  A61B2017/12095 ,  A61B2017/22061

    摘要： A partitioning device for separating a patient's heart chamber into a productive portion and a non-productive portion which is suitable for treating patients with heart disease, particularly congestive heart failure. The partitioning device has a reinforced membrane with outwardly biased members to help seal the periphery of the membrane against the wall of the patient's heart chamber. In one embodiment, the outwardly biased member is an expansive strand that extends between adjacent ribs of an expandable frame which reinforces the membrane. In another embodiment, the outwardly biased member is a hydrophilic body such as foam which swells upon contact with body fluid such as blood in the heart chamber. The reinforced membrane has a central hub with a distally extending support stem with a plurality of feet which extend radially from a centerline axis and preferably have ends that are aligned in a common plane. The ends of the pods which extend radially away from the centerline axis may be interconnected by flexible struts and/or webs.

    摘要翻译： 一种用于将患者心室分离为生产部分和非生产性部分的分配装置，其适用于治疗患有心脏病，特别是充血性心力衰竭的患者。 分隔装置具有增强的膜，其具有向外偏置的构件，以帮助将膜的周边密封抵靠患者心室的壁。 在一个实施例中，向外偏置的构件是在可扩展框架的相邻肋之间延伸的膨胀股线，其可加强膜。 在另一个实施方案中，向外偏压的构件是亲水体，例如泡沫，当与心液室中的体液如血液接触时膨胀。 加强膜具有中心毂，其具有远端延伸的支撑杆，多个脚从中心线径向延伸，并且优选地具有在公共平面中对准的端部。 从径向远离中心线轴线延伸的荚的端部可通过柔性支柱和/或腹板相互连接。

    Electrosurgical instrument having a predetermined heat profile
    6.
    发明授权
    Electrosurgical instrument having a predetermined heat profile 失效
    具有预定热分布的电外科器械

    公开(公告)号：US06757565B2

    公开(公告)日：2004-06-29

    申请号：US10071470

    申请日：2002-02-08

    申请人： Hugh R. Sharkey ,  John E. Ashley ,  Kobi Iki

    发明人： Hugh R. Sharkey ,  John E. Ashley ,  Kobi Iki

    IPC分类号： A61F712

    CPC分类号： A61B18/148

    摘要： An electrosurgical instrument is provided, having a holding formation, an elongated probe, an electrode, and a conductor. The elongated probe is connected to and extends from the holding formation. The electrode is located on an end of the elongated probe opposing the holding formation, and has a leading edge and a face. The electrode is locatable so that the face is substantially in a horizontal plane and the leading edge is above the horizontal plane. The conductor extends along the elongated probe and has a portion connected to the electrode to provide RF power thereto. The electrode creates a temperature profile with a temperature adjacent to the leading edge being higher than a temperature adjacent to the face.

    摘要翻译： 提供了一种具有保持结构，细长探针，电极和导体的电外科器械。 细长的探针连接到保持结构并从保持结构延伸。 电极位于与保持结构相对的细长探针的端部上，并且具有前缘和面。 电极是可定位的，使得所述面基本上处于水平面并且前缘在水平面之上。 导体沿着细长的探针延伸并且具有连接到电极的部分以向其提供RF功率。 电极产生温度曲线，其中与前缘相邻的温度高于与面相邻的温度。

    Electrosurgical instrument having a chamber to volatize a liquid
    8.
    发明授权
    Electrosurgical instrument having a chamber to volatize a liquid 有权
    电外科器械具有使液体挥发的室

    公开(公告)号：US06699244B2

    公开(公告)日：2004-03-02

    申请号：US10124954

    申请日：2002-04-17

    申请人： J. Remberto Carranza ,  Hugh R. Sharkey ,  John E. Ashley ,  Gary S. Fanton

    发明人： J. Remberto Carranza ,  Hugh R. Sharkey ,  John E. Ashley ,  Gary S. Fanton

    IPC分类号： A61B1814

    CPC分类号： A61B18/148 ,  A61B18/1482 ,  A61B18/1492 ,  A61B2017/320008 ,  A61B2018/00434 ,  A61B2018/00625 ,  A61B2018/00654 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00797 ,  A61B2018/1472 ,  A61B2218/002 ,  A61N1/06 ,  A61N1/40

    摘要： An electrosurgical instrument is provided which includes a holding formation, a probe shaft, an electric conductor, and a probe tip. The probe shaft is secured to the holding formation and has an elongated section extending therefrom. The electric conductor extends along the elongated section. The probe tip is located on a distal end of the probe shaft opposing the holding formation. The probe tip defines a volatization chamber with a mouth out of the probe tip. The probe tip includes an electrode, to which RF current is provided through the electric conductor. The electrode heats an area adjacent to the probe tip. The electrode also heats a liquid in the first volatization chamber to evaporate the liquid into a vapor pocket that ejects from the first volatization chamber through the mouth out of the probe tip. A pump effect is created so that the liquid maintains the probe tip at a more stable temperature.

    摘要翻译： 提供了一种电外科器械，其包括保持结构，探针轴，电导体和探针尖端。 探头轴固定在保持结构上，并具有从其延伸的细长部分。 电导体沿着细长部分延伸。 探针尖端位于与保持结构相对的探针轴的远端上。 探针尖端限定了具有探针尖端的口的挥发室。 探针尖端包括电极，通过电导体提供RF电流。 电极加热与探针尖端相邻的区域。 电极还加热第一挥发室中的液体以将液体蒸发成从第一挥发室通过探针尖端喷出的蒸气袋。 产生泵效应，使得液体将探针尖端保持在更稳定的温度。

    Soft tissue heating apparatus with independent, cooperative heating sources
    10.
    发明授权
    Soft tissue heating apparatus with independent, cooperative heating sources 有权
    软组织加热装置具有独立的协调加热源

    公开(公告)号：US06358273B1

    公开(公告)日：2002-03-19

    申请号：US09289459

    申请日：1999-04-09

    申请人： Bruno Strul ,  Hugh R. Sharkey ,  Daren L. Stewart

    发明人： Bruno Strul ,  Hugh R. Sharkey ,  Daren L. Stewart

    IPC分类号： A61F700

    CPC分类号： A61B18/148 ,  A61B18/1492 ,  A61B2018/00005 ,  A61B2018/00714 ,  A61B2018/00791 ,  A61B2018/00815 ,  A61B2018/1253

    摘要： A medical probe for the heating of soft tissue, such as collagen tissue, wherein the medical probe has an elongated body with a proximal and distal end, a heating source, an RF electrode. Optional components include a thermocouple, and an insulative sleeve. The probe's elongated body is preferably hollow and flexible. The RF electrode and the heating source are powered by independently controlled power sources and cooperate to maintain a constant and smooth temperature to the distal end of the RF electrode. The heating source may be a contained liquid, such as saline, or an electrothermal mass, such as a ferrite, a toroid, a resistive element, or the like. Current induced from the conductor to the heating source creates heat in the heating source. The thermocouple measures the temperature of the heating source and adjusts the power to the conductor to maintain the heating source's temperature.

    摘要翻译： 用于加热软组织（例如胶原组织）的医疗探针，其中医疗探针具有带近端和远端的细长体，加热源，RF电极。 可选组件包括热电偶和绝缘套管。 探头的细长体优选是中空的和柔性的。 RF电极和加热源由独立控制的电源供电，并协调以保持恒定且平稳的温度到RF电极的远端。 加热源可以是诸如盐水的包含的液体，或诸如铁氧体，环形线圈，电阻元件等的电热物质。 从导体引导到加热源的电流在加热源中产生热量。 热电偶测量加热源的温度，并调整导体的功率以保持加热源的温度。