公开(公告)号：US12077789B2

公开(公告)日：2024-09-03

申请号：US17829866

申请日：2022-06-01

Applicant: ILLUMINA, INC.

Inventor： Misha Golynskiy ,  Mariko Matsuura ,  Saurabh Nirantar ,  Hamed Tabatabaei Ghomi ,  Seth McDonald ,  Ryan Craig ,  Sergio Peisajovich ,  Kyrie Johnson ,  Kay Klausing ,  Eric Murtfeldt ,  Alexandra Exner

IPC: C12N9/12 ,  C12Q1/6874

CPC classification number: C12N9/1252 ,  C12Q1/6874 ,  C12Y207/07007

Abstract: Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain low pre-phasing rates when using ambiently stored polymerases, as well as methods and kits using the same.

公开(公告)号：US20230047225A1

公开(公告)日：2023-02-16

申请号：US17829866

申请日：2022-06-01

Applicant: ILLUMINA, INC. ,  ILLUMINA CAMBRIDGE LIMITED ,  ILLUMINA SINGAPORE PTE. LTD.

Inventor： Misha Golynskiy ,  Mariko Matsuura ,  Saurabh Nirantar ,  Hamed Tabatabaei Ghomi ,  Seth McDonald ,  Ryan Craig ,  Sergio Peisajovich ,  Kyrie Johnson ,  Kay Klausing ,  Eric Murtfeldt ,  Alexandra Exner

IPC: C12N9/12 ,  C12Q1/6874

Abstract: Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain low pre-phasing rates when using ambiently stored polymerases, as well as methods and kits using the same.