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公开(公告)号：US12077789B2
公开(公告)日：2024-09-03
申请号：US17829866
申请日：2022-06-01
申请人： ILLUMINA, INC.
发明人： Misha Golynskiy , Mariko Matsuura , Saurabh Nirantar , Hamed Tabatabaei Ghomi , Seth McDonald , Ryan Craig , Sergio Peisajovich , Kyrie Johnson , Kay Klausing , Eric Murtfeldt , Alexandra Exner
IPC分类号： C12N9/12 , C12Q1/6874
CPC分类号： C12N9/1252 , C12Q1/6874 , C12Y207/07007
摘要： Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain low pre-phasing rates when using ambiently stored polymerases, as well as methods and kits using the same.
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公开(公告)号：US20240141427A1
公开(公告)日：2024-05-02
申请号：US18373620
申请日：2023-09-27
申请人： ILLUMINA, INC.
发明人： Misha Golynskiy , Rahman Rahman Pour , Jiawen Li , Ryan Craig , Hamed Tabatabaei Ghomi , Saurabh Nirantar , Hsu Myat Noe , Lin Hui Chang , Yvonne Devadas , Jing Wen Lim , Kay Klausing , Humberto Rojo , Eric Murtfeldt , Chris Garcia
IPC分类号： C12Q1/6874 , C12N9/12
CPC分类号： C12Q1/6874 , C12N9/1252 , C12Y207/07007
摘要： Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain low error rate, low phasing rate, or increased incorporation rate for a second generation ffN under reduced incorporation times, as well as methods and kits using the same.
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公开(公告)号：US20230047225A1
公开(公告)日：2023-02-16
申请号：US17829866
申请日：2022-06-01
发明人： Misha Golynskiy , Mariko Matsuura , Saurabh Nirantar , Hamed Tabatabaei Ghomi , Seth McDonald , Ryan Craig , Sergio Peisajovich , Kyrie Johnson , Kay Klausing , Eric Murtfeldt , Alexandra Exner
IPC分类号： C12N9/12 , C12Q1/6874
摘要： Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain low pre-phasing rates when using ambiently stored polymerases, as well as methods and kits using the same.
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