摘要:
A polymerizable monomer adhesive composition includes a 1,1-disubstituted ethylene monomer and at least one slip additive, where the slip additive causes a polymer film formed from the monomer to have a lower coefficient of friction than in an absence of the slip additive. The slip additive can be selected from, inter alia, fluorinated monomers or polymers, fluorinated additives, siloxane-containing monomers or polymers, siloxane-containing additives, fluorinated siloxanes, and long chain fatty acid esters. The slip additive can also form a second phase in a resultant polymer film, where the second phase is soluble in the monomer but is insoluble or substantially insoluble in the polymer.
摘要:
A disposable applicator includes a generally tubular applicator body having a closed proximal end and an open distal end and a frangible vial inside. The proximal end is covered by a drying swab while the distal end is covered by an applicator swab that is in open communication with the interior of the applicator body. Within the applicator body is a frangible vial containing a biomedically useful liquid composition, such as an &agr;-cyanoacrylate adhesive, a medicament, or both. The applicator is useful for applying liquid compositions to target sites such as tissue, particularly sites of topical pathology, such as stomatitis lesions.
摘要:
An adhesive composition that contains a preservative is particularly useful as a medical adhesive and can include alkyl cyanoacrylate monomers. The preservative is preferably soluble in the monomer. The composition may optionally be sterilized by placing a mixture of a polymerizable adhesive monomer and a preservative in a container, sealing the container, and sterilizing the mixture and the container.
摘要:
A composition comprising a polymerizable adhesive monomer is applied over a biologically active initiator or accelerator for polymerization of the monomer. The biologically active initiator or accelerator is a medicament that provides a desired medical or therapeutic activity as well as enhancing polymerization of the adhesive.
摘要:
An adhesive composition is provided including one or more polymerizable cyanoacrylate monomers and boron trifluoride as a stabilizer or complexing agent. The adhesive composition may also include or be used with a decomplexing agent, particularly one or more quaternary ammonium fluoride salts or one or more quaternary ammonium ether salts. A polymerization initiator or accelerator may also be used. The viscosity of the adhesive composition may be controlled by addition of a thickening agent which may be a polymer or copolymer catalyzed by a boron trifluoride complex or compound. Methods for the application of the adhesive compositions to living tissue are also provided.
摘要:
This invention relates to a process for preparing quinacridone pigment compositions by (a) heating a reaction mixture containing (i) 2,5-dianilinoterephthalic acid or 2,5-dianilino-6,13-dihydroterephthalic acid or a derivative thereof, (ii) about 0.1 to about 5 percent, based on component (a)(i), of 2,5-di(sulfamoylanilino)terephthalic acid and/or 2,5-di(sulfamoylanilino)-6,13-dihydroterephthalic acid or a derivative thereof, (iii) about 0.1 to about 15 percent by weight, based on component (a)(i), of other sulfonyl-containing derivatives of 2,5-dianilinoterephthalic acid and/or 2,5-dianilino-6,13-dihydroterephthalic acid, (iv) about 3 to about 20 parts by weight, per part of component (a)(i), of a dehydrating agent, and (v) optionally, a solvent; (b) drowning the reaction mixture from step (a) with a liquid in which the quinacridone pigment composition is substantially insoluble; and (c) isolating the quinacridone pigment composition.
摘要:
This invention relates to pigment compositions containing an organic pigment treated with a pigment derivative having the formula (I) ##STR1## wherein Q represents an organic pigment moiety;X is O, S, or N--R.sup.1 ;Y is N--R.sup.2, O, or a direct bond;Z is --CO--, --Alk--, --Ar--, or chemically reasonable combinations thereof;Alk is C.sub.1 -C.sub.5 alkylene, C.sub.2 -C.sub.5 alkenylene, or C.sub.4 -C.sub.5 alkadienylene, or substituted derivatives thereof;Ar is arylene;R.sup.1 is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.7 -C.sub.16 aralkyl, or --CN; andR.sup.2 is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.5 -C.sub.7 cycloalkyl, C.sub.7 -C.sub.16 aralkyl, or C.sub.6 -C.sub.10 aryl;with the provisos that(1) the cyclic moiety represented by the formula ##STR2## must be a four- to seven-membered ring, (2) Z can contain a C.dbd.O group adjacent to the nitrogen atom of the Q--CH.sub.2 --N moiety only if Y is N--R.sup.2 or O, and(3) X can be O only if Y is N--R.sup.2 or O.
摘要:
A polymerizable adhesive composition comprises at least one α-cyanoacrylate monomer and at least one absorbable viscosity modifying agent. The absorbable viscosity modifying agent has repeated units of the following structure: R1 is a methyl group or a hydrogen. R2 is a straight, branched or cyclic alkyl group having from 1 to 6 carbon atoms. R3 is a straight, branched or cyclic alkyl group having from 1 to 12 carbon atoms, and n is 2 or more.
摘要:
This invention relates to a process for preparing pigment compositions comprising (a) treating an organic pigment with (1) about 0.1 to about 100% by weight, relative to the organic pigment, of a tertiary alkyl primary amine having the formula (I) ##STR1## wherein R.sup.1 is a C.sub.5 -C.sub.30 (cyclo)aliphatic group, and R.sup.2 and R.sup.3 are independently C.sub.1 -C.sub.6 alkyl, (2) 0 to about 100% by weight, relative to the organic pigment, of a surfactant, and (3) about 5 to about 15 parts by weight per part by weight of the organic pigment of a liquid in which the organic pigment is substantially insoluble, thereby forming a suspension of the surface-treated pigment composition in the liquid; and (b) collecting the pigment composition.
摘要:
This invention relates to a process for the preparation of quinacridone pigments by (a) heating, at a temperature of about 80.degree. C. to about 145.degree. C., a reaction mixture containing (i) 2,5-dianilinoterephthalic acid, a 2,5-dianilino-3,6-dihydroterephthalic acid ester, and/or a derivative thereof, (ii) about 3 to about 15 parts by weight, per part of component (a)(i), of a dehydrating agent, and (iii) about 0.1 to about 15 percent by weight, based on component (a)(i), of one or more non-pigmentary aromatic polycyclic compounds and/or derivatives thereof, with the proviso that if component (a)(i) is a 2,5-dianilino-3,6-dihydroterephthalic acid ester or a derivative thereof, reaction step (a) additionally comprises an oxidation step; (b) drowning the reaction mixture from step (a) by adding said reaction mixture to about 3 to about 15 parts by weight, per part of component (a)(i), of a liquid in which the quinacridone pigment is substantially insoluble; (c) isolating the quinacridone pigment; (d) optionally, conditioning the quinacridone pigment; and (e) optionally, blending the resultant pigment with one or more quinacridone derivatives.