-
1.发明申请Macroporous, resorbable and injectible calcium phosphate-based cements (MCPC) for bone repair, augmentation, regeneration, and osteoporosis treatment 有权用于骨修复，增生，再生和骨质疏松症治疗的大孔，可吸收和可注射的磷酸钙基水泥（MCPC）公开(公告)号：US20050199156A1
公开(公告)日：2005-09-15
申请号：US11054623
申请日：2005-02-09
申请人： Ibrahim Khairoun , Racquel LeGeros , Guy Daculsi , Jean-Michael Bouler , Jerome Guicheux , Olivier Gauthier
发明人： Ibrahim Khairoun , Racquel LeGeros , Guy Daculsi , Jean-Michael Bouler , Jerome Guicheux , Olivier Gauthier
CPC分类号： C04B28/344 , A61L24/02 , A61L27/12 , A61L2430/02 , C04B2111/00836 , C04B11/00 , C04B14/28 , C04B20/0076 , C04B38/0051 , C04B2103/0072
摘要： A composition and method for producing interconnective macroporous, resorbable and injectable calcium phosphate-based cements (MICPCs). The composition of the invention sets to poorly crystalline apatitic calcium phosphate after mixing a powder component and an aqueous solution. The multiphasic calcium phosphate components in the cement resorb at different rates allowing the timely replacement by new bone. The interconnected macroporosity in the cement allows for vascularization, entrapment of growth factors, cell colonization and tissue ingrowth. This MICPC can be used for dental and medical applications relating to bone repair, augmentation, reconstruction, regeneration, and osteoporosis treatment, and also for drug delivery, and as scaffolds for tissue engineering.
摘要翻译： 互连大孔，可吸收和可注射的磷酸钙基水泥（MICPC）的组合物和方法。 本发明的组合物在混合粉末组分和水溶液之后设定为不良结晶的磷灰石磷酸钙。 水泥中的多相磷酸钙组分以不同的速率吸收，允许及时更换新骨。 水泥中相互连接的大孔隙可以使血管形成，生长因子的截留，细胞定植和组织向内生长。 该MICPC可用于与骨修复，增强，重建，再生和骨质疏松症治疗以及用于药物递送以及组织工程支架相关的牙科和医疗应用。
-
2.发明授权Macroporous, resorbable and injectible calcium phosphate-based cements (MCPC) for bone repair, augmentation, regeneration, and osteoporosis treatment 有权用于骨修复，增生，再生和骨质疏松症治疗的大孔，可吸收和可注射的磷酸钙基水泥（MCPC）公开(公告)号：US07351280B2
公开(公告)日：2008-04-01
申请号：US11054623
申请日：2005-02-09
申请人： Ibrahim Khairoun , Racquel Z. LeGeros , Guy Daculsi , Jean-Michael Bouler , Jérôme Guicheux , Olivier Gauthier
发明人： Ibrahim Khairoun , Racquel Z. LeGeros , Guy Daculsi , Jean-Michael Bouler , Jérôme Guicheux , Olivier Gauthier
IPC分类号： C04B12/02
CPC分类号： C04B28/344 , A61L24/02 , A61L27/12 , A61L2430/02 , C04B2111/00836 , C04B11/00 , C04B14/28 , C04B20/0076 , C04B38/0051 , C04B2103/0072
摘要： A composition and method for producing interconnective macroporous, resorbable and injectable calcium phosphate-based cements (MICPCs). The composition of the invention sets to poorly crystalline apatitic calcium phosphate after mixing a powder component and an aqueous solution. The multiphasic calcium phosphate components in the cement resorb at different rates allowing the timely replacement by new bone. The interconnected macroporosity in the cement allows for vascularization, entrapment of growth factors, cell colonization and tissue ingrowth. This MICPC can be used for dental and medical applications relating to bone repair, augmentation, reconstruction, regeneration, and osteoporosis treatment, and also for drug delivery, and as scaffolds for tissue engineering.
摘要翻译： 互连大孔，可吸收和可注射的磷酸钙基水泥（MICPC）的组合物和方法。 本发明的组合物在混合粉末组分和水溶液之后设定为不良结晶的磷灰石磷酸钙。 水泥中的多相磷酸钙组分以不同的速率吸收，允许及时更换新骨。 水泥中相互连接的大孔隙可以使血管形成，生长因子的截留，细胞定植和组织向内生长。 该MICPC可用于与骨修复，增强，重建，再生和骨质疏松症治疗以及用于药物递送以及组织工程支架相关的牙科和医疗应用。
-
公开(公告)号：US20110142940A1
公开(公告)日：2011-06-16
申请号：US12811809
申请日：2009-01-06
申请人： Hervé Leguen , Rémi Cavagna , Ibrahim Khairoun , Elise Verron , Pascal Janvier , Olivier Gauthier , Jean-Michel Bouler
发明人： Hervé Leguen , Rémi Cavagna , Ibrahim Khairoun , Elise Verron , Pascal Janvier , Olivier Gauthier , Jean-Michel Bouler
IPC分类号： A61K9/14 , A61P19/08 , A61P23/02 , A61K31/445
CPC分类号： A61K47/02 , A61K9/0024 , A61K9/0063 , A61K9/19 , A61K31/00 , A61K31/167 , A61K31/445 , A61L24/0015 , A61L24/02 , A61L27/12 , A61L27/54 , A61L2300/402
摘要： The present invention concerns a composition useful as bone substitute comprising one or more calcium-phosphate compounds in association with an analgesic. It also refers to a preparation process of said composition, a preparation process of a drug-combined device comprising said composition, the drug combined device thus obtained, a kit comprising said composition and the use of said composition for the preparation of a drug-combined device useful for filling a bony defect caused in the iliac crest by collection of auto-graft bone, as a scaffold for tissue engineering and to produce a dental or bony implant.
摘要翻译： 本发明涉及用作骨替代物的组合物，其包含与止痛剂相关的一种或多种磷酸钙化合物。 其还涉及所述组合物的制备方法，包含所述组合物的药物组合装置的制备方法，由此获得的药物组合装置，包含所述组合物的试剂盒和所述组合物用于制备药物组合 装置，用于通过收集自体移植骨来填充由髂嵴引起的骨缺损，作为用于组织工程的支架并产生牙科或骨骼植入物。
-
公开(公告)号：US09642939B2
公开(公告)日：2017-05-09
申请号：US12438598
申请日：2007-08-23
CPC分类号： A61L27/46 , A61L24/0036 , A61L24/0042 , A61L24/0063 , A61L24/0084 , A61L27/56 , A61L27/58 , A61L2430/02
摘要： The present invention is directed to a novel cement powder comprising an organic component consisting of one or more biocompatible and bioresorbable polymers and an inorganic component consisting of one or more calcium phosphate compounds. The invention also relates to the apatitic CPC resulting from the mixing of said cement powder with a liquid phase and setting.
-
公开(公告)号：US20120111226A1
公开(公告)日：2012-05-10
申请号：US13255069
申请日：2010-03-03
申请人： Bruno Bujoli , Jean-Michel Bouler , Pascal Janvier , Ibrahim Khairoun , Verena Schnitzler , Charlotte Mellier
发明人： Bruno Bujoli , Jean-Michel Bouler , Pascal Janvier , Ibrahim Khairoun , Verena Schnitzler , Charlotte Mellier
IPC分类号： C04B12/02
CPC分类号： A61L24/0042 , A61L24/0063 , A61L27/12 , A61L27/46 , A61L27/58 , C01B25/32 , C01B25/45 , C04B35/447
摘要： The present invention relates to a galliated calcium-phosphate biomaterial comprising a gallium-doped phosphocalcic compound of formula (I): Ca(005-1 5X)Gax(PO—O4)7, wherein 0
摘要翻译： 本发明涉及包含式（I）的掺杂镓的磷酸钙化合物：Ca（005-1 5X）Gax（PO-O4）7，其中0
-
公开(公告)号：US20120064170A1
公开(公告)日：2012-03-15
申请号：US13255076
申请日：2010-03-03
CPC分类号： A61L24/0042 , A61L24/0063 , A61L27/12 , A61L27/46 , A61L27/58 , C01B25/32 , C01B25/45 , C04B35/447
摘要： The present invention relates to a gallium-doped phosphocalcic compound of formula (I): Ca(10.5-1.5x)Gax(PO4)7, wherein 0
摘要翻译： 本发明涉及式（I）的掺杂镓的磷酸钙化合物：Ca（10.5-1.5x）Gax（PO4）7，其中0
-
7.发明授权公开(公告)号：US08889165B2
公开(公告)日：2014-11-18
申请号：US12031562
申请日：2008-02-14
CPC分类号： A61L27/12 , A61L24/001 , A61L24/0063 , A61L24/02 , A61L27/20 , A61L27/50 , A61L27/54 , A61L2400/06 , A61L2430/02
摘要： The present invention relates to a macroporous, resorbable and injectable apatitic calcium-phosphate cement with a high compressive strength useful as bone cement and releasing a bone resorption inhibitor, preparation method and uses thereof.
摘要翻译： 本发明涉及一种具有高抗压强度的大孔，可吸收和可注射的磷酸钙水泥，其可用作骨水泥并释放骨吸收抑制剂，其制备方法和用途。
-
公开(公告)号：US20140087004A1
公开(公告)日：2014-03-27
申请号：US14094314
申请日：2013-12-02
IPC分类号： A61K33/42
CPC分类号： A61K33/42 , A61K6/033 , A61K6/0643 , A61L27/12 , A61L27/32 , C01B25/32 , C01B25/45 , C04B12/02 , C04B28/34 , C04B35/447 , C04B2111/00836 , C04B2235/3208 , C04B2235/3212 , C04B2235/3286 , C04B2235/44 , C04B2235/442 , C04B2235/443 , C04B2235/444 , C04B2235/445 , C04B2235/448 , C04B2235/449 , C04B2235/76 , C04B2235/761 , A61K6/02
摘要： The present invention relates to a gallium-doped phosphocalcic compound of formula (I): Ca(10.5−1.5x)Gax(PO4)7 (I) wherein 0
摘要翻译： 本发明涉及式（I）的掺杂镓的磷酸钙化合物：其中0
-
公开(公告)号：US08623311B2
公开(公告)日：2014-01-07
申请号：US12716862
申请日：2010-03-03
IPC分类号： C01B25/32
CPC分类号： A61K33/42 , A61K6/033 , A61K6/0643 , A61L27/12 , A61L27/32 , C01B25/32 , C01B25/45 , C04B12/02 , C04B28/34 , C04B35/447 , C04B2111/00836 , C04B2235/3208 , C04B2235/3212 , C04B2235/3286 , C04B2235/44 , C04B2235/442 , C04B2235/443 , C04B2235/444 , C04B2235/445 , C04B2235/448 , C04B2235/449 , C04B2235/76 , C04B2235/761 , A61K6/02
摘要： The present invention relates to a gallium-doped phosphocalcic compound of formula (I): Ca(10.5-1.5x)Gax(PO4)7 (I) wherein 0
摘要翻译： 本发明涉及式（I）的掺杂镓的磷酸钙化合物：其中0
-
10.发明申请公开(公告)号：US20100197636A1
公开(公告)日：2010-08-05
申请号：US12527228
申请日：2008-02-13
IPC分类号： A61K31/663 , A61P19/08
CPC分类号： A61L27/12 , A61L24/001 , A61L24/0063 , A61L24/02 , A61L27/20 , A61L27/50 , A61L27/54 , A61L2400/06 , A61L2430/02
摘要： The present invention relates to a macroporous, resorbable and injectable apatitic calcium-phosphate cement with a high compressive strength useful as bone cement and releasing a bone resorption inhibitor, preparation method and uses thereof.
摘要翻译： 本发明涉及一种具有高抗压强度的大孔，可吸收和可注射的磷酸钙水泥，其可用作骨水泥并释放骨吸收抑制剂，其制备方法和用途。
-
-
-
-
-
-
-
-
-
搜索结果
15 条记录 (耗时 0.027 秒)
