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公开(公告)号：US08124026B2
公开(公告)日：2012-02-28
申请号：US12718139
申请日：2010-03-05
IPC分类号： B01L3/00
CPC分类号： B01L3/50273 , B01L2200/0673 , B01L2200/10 , B01L2300/0816 , B01L2400/0406 , B01L2400/0418 , F04B19/006 , Y10T436/2575
摘要： Devices with lateral flow elements and integral fluidics are disclosed. The integral fluidics consist of injector pumps comprised of fluidic elements under instrument control. The fluidic element of an injector pump is fluidically connected to lateral flow elements and can be used to control fluid entry into containment chambers referred to as micro-reactors. The lateral flow elements comprise conductor elements that can be used for sample application and transport of analyte contained in the sample to the micro-reactor. Fluidic transport through the fluidic element of the injector pump is under instrument-control. Both the lateral flow element and the fluidic element may contain chemical entities incorporated along their length. The chemical reactions that can be used for analyte detection using the devices are described. Also described are methods of manufacture of these devices.
摘要翻译： 公开了具有侧向流动元件和整体流体的装置。 积分流体由在仪器控制下由流体元素组成的喷射泵组成。 注射器泵的流体元件流体连接到侧向流动元件，并且可以用于控制流体进入称为微反应器的容纳室中。 横向流动元件包括导体元件，其可以用于将样品中包含的分析物的样品应用和运送到微反应器。 通过注射泵的流体元件的流体传输是在仪器控制下。 侧流元件和流体元件都可以包含沿其长度并入的化学物质。 描述了可用于使用装置进行分析物检测的化学反应。 还描述了这些装置的制造方法。
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公开(公告)号：US07201833B2
公开(公告)日：2007-04-10
申请号：US10307468
申请日：2002-12-02
IPC分类号： G01N33/487
CPC分类号： B01L3/5023 , B01J2219/00286 , B01J2219/00358 , B01J2219/00605 , B01J2219/00612 , B01J2219/00621 , B01J2219/00722 , B01J2219/00725 , B01J2219/00783 , B01J2219/00831 , B01J2219/00853 , B01J2219/0086 , B01L3/502707 , B01L3/50273 , B01L3/502753 , B01L2200/12 , B01L2200/16 , B01L2300/0645 , B01L2300/0825 , B01L2300/10 , B01L2400/0415 , B01L2400/0418 , G01N33/6845 , G01N2035/00158
摘要： The invention is directed to analytical devices and micro-arrays with integral fluidic inputs and outputs. The devices are constructed from planar solid-phase hydrophilic matrix circuits containing dry chemical reagents overlaying integral electro-kinetic pumping electrodes. The hydrophilic matrix circuits are enclosed within a gas permeable electrical insulator. The devices are for use in micro-scale bio-analysis, mixture separation and reaction.
摘要翻译： 本发明涉及具有积分流体输入和输出的分析装置和微阵列。 这些器件由平面固相亲水基质电路构成，其包含覆盖整体电动泵浦电极的干化学试剂。 亲水基质电路封闭在透气电绝缘体内。 该装置用于微量生物分析，混合物分离和反应。
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公开(公告)号：US07722817B2
公开(公告)日：2010-05-25
申请号：US10649683
申请日：2003-08-28
IPC分类号： B01L3/00
CPC分类号： B01L3/50273 , B01L2200/0673 , B01L2200/10 , B01L2300/0816 , B01L2400/0406 , B01L2400/0418 , F04B19/006 , Y10T436/2575
摘要： Devices with lateral flow elements and integral fluidics are disclosed. The integral fluidics consist of injector pumps comprised of fluidic elements under instrument control. The fluidic element of an injector pump is fluidically connected to lateral flow elements and can be used to control fluid entry into containment chambers referred to as micro-reactors. The lateral flow elements comprise conductor elements that can be used for sample application and transport of analyte contained in the sample to the micro-reactor. Fluidic transport through the fluidic element of the injector pump is under instrument-control. Both the lateral flow element and the fluidic element may contain chemical entities incorporated along their length. The chemical reactions that can be used for analyte detection using the devices are described. Also described are methods of manufacture of these devices.
摘要翻译： 公开了具有侧向流动元件和整体流体的装置。 积分流体由在仪器控制下由流体元素组成的喷射泵组成。 注射器泵的流体元件流体连接到侧向流动元件，并且可以用于控制流体进入称为微反应器的容纳室中。 横向流动元件包括导体元件，其可以用于将样品中包含的分析物的样品应用和运送到微反应器。 通过注射泵的流体元件的流体传输是在仪器控制下。 侧流元件和流体元件都可以包含沿其长度并入的化学物质。 描述了可用于使用装置进行分析物检测的化学反应。 还描述了这些装置的制造方法。
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