公开(公告)号：US20140134734A1

公开(公告)日：2014-05-15

申请号：US13713327

申请日：2012-12-13

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Pei-Ju LIN ,  Guilhem TOURNIAIRE ,  Yi-Chen CHEN ,  Kathryn SWINDELLS ,  Bin-Ru SHE ,  Hsiang-Chun HSU ,  Chih-Ching LIAO ,  Su-Yo LIN

IPC: C12N5/00

CPC classification number: C12N5/0031 ,  C08F220/06 ,  C08F220/14 ,  C08F220/18 ,  C08F220/28 ,  C08F222/26 ,  C12N5/0037 ,  C12N5/0068 ,  C12N2533/30

Abstract: The disclosure provides a cell culture system and a serum-free method for cultivating cells. The cell culture system includes a substratum, wherein the substratum has a surface. A polymer is disposed on the surface of the substratum, wherein the polymer is prepared by polymerizing a first monomer with a second monomer. The first monomer has a structure as represented by Formula (I), and the second monomer has a structure as represented by Formula (II): wherein, R1 is hydrogen or methyl; R2 is methyl, ethyl, or —CH2CH2OCH3; R3 is hydrogen or methyl; and, R4 is hydrogen, —CH2CH2OCOCHCHCOOH, —CH2CH2OCOCH2CH2COOH, or —CH2CH2COOH.

Abstract translation: 本公开提供了一种培养细胞的细胞培养系统和无血清方法。 细胞培养系统包括底物，其中底物具有表面。 聚合物设置在基底的表面上，其中聚合物通过使第一单体与第二单体聚合来制备。 第一单体具有由式（I）表示的结构，第二单体具有由式（II）表示的结构：其中，R 1为氢或甲基; R2是甲基，乙基或-CH2CH2OCH3; R3是氢或甲基; 和R 4是氢，-CH 2 CH 2 OCOCHCHCOOH，-CH 2 CH 2 OCOCH 2 CH 2 COOH或-CH 2 CH 2 COOH。

公开(公告)号：US20220204936A1

公开(公告)日：2022-06-30

申请号：US17475794

申请日：2021-09-15

Applicant: Industrial Technology Research Institute

Inventor： Yu-Bing LIOU ,  Chih-Ching LIAO ,  Hsin-Yi HSU ,  Ying-Wen SHEN ,  Yun-Chung TENG ,  Hsin-Hsin SHEN ,  Yi-Chen CHEN

IPC: C12N5/077 ,  C08J5/18

Abstract: A non-fibrous film of which the composition includes a collagen and a polyester polymer is provided. A content of the polyester polymer in the non-fibrous film is 1-60 wt %. Moreover, the non-fibrous film has a swelling rate of 1-200 μm/hour or a swelling proportion per unit time of 0.1-2%/hour in an aqueous liquid.

公开(公告)号：US20190143284A1

公开(公告)日：2019-05-16

申请号：US15922163

申请日：2018-03-15

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Yuan-Fa LEE ,  Shun-Sheng KO ,  Yen-Bor FANG ,  Chih-Hung HUANG ,  Li-Wen LAI ,  Chih-Ching LIAO

IPC: B01F11/00 ,  C12M3/06 ,  C12M3/04 ,  C12M1/34

Abstract: A shaking system of cell culture includes a shaking unit, a side visual unit, a top visual unit and a control unit. The side visual unit is located at one side of the shaking unit. The top visual unit is located above the shaking unit. The control unit is coupled signally with the shaking unit, the side visual and the top visual unit. In addition, a shaking method of cell culture is provided as well.