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公开(公告)号：US10656232B2
公开(公告)日：2020-05-19
申请号：US14498982
申请日：2014-09-26
发明人： David Berman , Dylan J. Boday , Icko E. T. Iben , Wayne I. Imaino , Stephen L. Schwartz , Anna W. Topol , Daniel J. Winarski
摘要： Described are embodiments to calibrate read sensors, which in turn may ensure that the equipment utilized to detect antigens is reliable and accurate. If it is determined that a read sensor is degraded a method of calibrating a read sensor of a read head may be used.
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公开(公告)号：US10261102B2
公开(公告)日：2019-04-16
申请号：US14879056
申请日：2015-10-08
IPC分类号： B01L3/00 , G01N35/00 , G01N33/487 , G01N33/553 , G06F3/06
摘要： Embodiments of the disclosure relate to a biosample plate that includes a memory component for storing biosample identification and analysis data, and a wireless communication interface for transferring the data to and from the biosample plate. In one embodiment, the biosample plate comprises a base for receiving a biosample, a memory component coupled to the base for storing identification and analysis information related to the biosample, and a wireless communication interface coupled to the memory component for transferring the information to and from the memory component. The wireless communication interface may include an electromagnetic device.
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公开(公告)号：US10012706B2
公开(公告)日：2018-07-03
申请号：US15093599
申请日：2016-04-07
CPC分类号： G01R33/091 , G01N27/72 , G01R33/093 , G01R33/1269
摘要： The invention relates to the identification of molecules using an apparatus which includes: a head module comprising: an electromagnetic write-head configured to magnetically excite the molecule to be identified with an alternating magnetic field; and a magneto-resistive read sensor for measuring a resonant response of the magnetically excited molecule to be identified. The apparatus also includes a processor coupled to the magneto-resistive sensor, the processor being configured to compare the resonant response to a table of known resonant responses to identify a chemical composition of the molecule to be identified.
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公开(公告)号：US20150015246A1
公开(公告)日：2015-01-15
申请号：US14498982
申请日：2014-09-26
发明人： David Berman , Dylan J. Boday , Icko E. T. Iben , Wayne I. Imaino , Stephen L. Schwartz , Anna W. Topol , Daniel J. Winarski
CPC分类号： G01R35/00 , G01N27/04 , G01N27/72 , G01N33/53 , G01R33/0035 , G01R33/1207
摘要： Described are embodiments to calibrate read sensors, which in turn may ensure that the equipment utilized to detect antigens is reliable and accurate. If it is determined that a read sensor is degraded a method of calibrating a read sensor of a read head may be used.
摘要翻译： 描述了校准读取传感器的实施例，其进而可以确保用于检测抗原的设备是可靠和准确的。 如果确定读取传感器劣化，则可以使用校准读取头的读取传感器的方法。
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5.发明申请CARTRIDGE FOR STORING BIOSAMPLE PLATES AND USE IN AUTOMATED DATA STORAGE SYSTEMS 有权用于存储生物活化板和用于自动数据存储系统的盒子公开(公告)号：US20140018265A1
公开(公告)日：2014-01-16
申请号：US14029667
申请日：2013-09-17
发明人： Allen K. Bates , Nils Haustein , James W. Johnson , Stephen L. Schwartz , Anna W. Topol , Daniel J. Winarski
IPC分类号： G01N33/487
CPC分类号： G01N33/48778 , G11B23/023 , G11B23/042 , G11B23/049
摘要： In one embodiment, a biosample storage cartridge includes an enclosure having a same form factor as a data tape cartridge configured for use in an automated tape library; and a holder disposed in the enclosure. In another embodiment, a biosample storage cartridge includes an enclosure and a holder disposed in the enclosure; the holder is configured to receive one or more biosamples, the cartridge is structurally configured to be picked by a picker of an access robot that is configured to pick a data tape cartridge in an automated tape library. In still another embodiment, an analytical system includes a bioanalysis drive configured to perform bioanalysis on one or more biosamples received from at least one biosample storage cartridge.
摘要翻译： 在一个实施例中，生物样本存储盒包括具有与被配置用于自动化磁带库中的数据磁带盒相同形状因数的外壳; 以及设置在外壳中的保持器。 在另一个实施例中，生物样本存储盒包括外壳和设置在外壳中的保持器; 保持器被配置为接收一个或多个生物样本，该盒被结构化地配置为由被配置为在自动磁带库中拾取数据磁带盒的访问机器人的拾取器拾取。 在另一个实施方案中，分析系统包括生物分析驱动器，其被配置为对从至少一个生物样本存储盒收到的一个或多个生物样本进行生物分析。
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公开(公告)号：US11408947B2
公开(公告)日：2022-08-09
申请号：US16424220
申请日：2019-05-28
摘要： The inventive concepts presented herein relate to methods of identifying molecules identification of molecules using apparatuses including: electromagnetic write-head(s); magneto-resistive read sensor(s), and processor(s). An exemplary method includes scanning one or more of a plurality of biosample tracks of a biosample substrate using an electromagnetic write-head to magnetically excite one or more molecules of interest using an alternating magnetic field. The one or more molecules of interest are disposed on one or more of the biosample tracks. A resonant response of the one or more molecules of interest is measured using a magneto-resistive sensor. The resonant response is compared to a table of known resonant responses to identify the one or more molecules of interest.
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7.发明申请公开(公告)号：US20190317160A1
公开(公告)日：2019-10-17
申请号：US16424220
申请日：2019-05-28
摘要： The inventive concepts presented herein relate to methods of identifying molecules identification of molecules using apparatuses including: electromagnetic write-head(s); magneto-resistive read sensor(s), and processor(s). An exemplary method includes scanning one or more of a plurality of biosample tracks of a biosample substrate using an electromagnetic write-head to magnetically excite one or more molecules of interest using an alternating magnetic field. The one or more molecules of interest are disposed on one or more of the biosample tracks. A resonant response of the one or more molecules of interest is measured using a magneto-resistive sensor. The resonant response is compared to a table of known resonant responses to identify the one or more molecules of interest.
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公开(公告)号：US10132804B2
公开(公告)日：2018-11-20
申请号：US15169479
申请日：2016-05-31
IPC分类号： G01N33/543 , G01N15/10 , B82Y15/00 , B82Y5/00
摘要： Described are embodiments of an invention for a sample assembly with an electrical conductor for detection of the antigens by electromagnetic read heads. In one embodiment, a sample assembly includes: a substrate; one or more base layers above the substrate; an outer layer above the one or more base layers; a plurality of sample trenches formed in the outer layer and/or the one or more base layers, each sample trench being characterized by an upper surface, a bottom surface, and a longitudinal axis; an electrical conductor disposed in the substrate, the electrical conductor being configured to generate an electromagnetic field in proximity to the plurality of sample trenches to enhance nanoparticle movement toward the bottom surface of the plurality of sample trenches; and at least one alignment trench formed above the substrate, each alignment trench having a longitudinal axis substantially parallel to a longitudinal axis of at least one of the sample trenches.
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9.发明申请SAMPLE ASSEMBLY WITH AN ELECTROMAGNETIC FIELD TO ACCELERATE THE BONDING OF TARGET ANTIGENS AND NANOPARTICLES 审中-公开具有电磁场的样品组件可以加速目标抗原和纳米颗粒的结合公开(公告)号：US20160274102A1
公开(公告)日：2016-09-22
申请号：US15169479
申请日：2016-05-31
IPC分类号： G01N33/543
CPC分类号： G01N33/54386 , B82Y5/00 , B82Y15/00 , G01N15/1031 , G01N33/54326 , G01N33/54333 , G01N33/54346 , G01N33/54353 , G01N33/54366 , G01N33/54393
摘要： Described are embodiments of an invention for a sample assembly with an electrical conductor for detection of the antigens by electromagnetic read heads. In one embodiment, a sample assembly includes: a substrate; one or more base layers above the substrate; an outer layer above the one or more base layers; a plurality of sample trenches formed in the outer layer and/or the one or more base layers, each sample trench being characterized by an upper surface, a bottom surface, and a longitudinal axis; an electrical conductor disposed in the substrate, the electrical conductor being configured to generate an electromagnetic field in proximity to the plurality of sample trenches to enhance nanoparticle movement toward the bottom surface of the plurality of sample trenches; and at least one alignment trench formed above the substrate, each alignment trench having a longitudinal axis substantially parallel to a longitudinal axis of at least one of the sample trenches.
摘要翻译： 描述了用于具有用于通过电磁读取头检测抗原的电导体的样本组件的发明的实施例。 在一个实施例中，样品组件包括：基底; 在基底上方一个或多个基层; 在一个或多个基层上方的外层; 形成在外层和/或一个或多个基层中的多个样品沟槽，每个样品沟槽的特征在于上表面，底表面和纵向轴线; 设置在所述基板中的电导体，所述电导体被配置为在所述多个样品沟槽附近产生电磁场，以增强朝向所述多个样品沟槽的底表面的纳米颗粒运动; 以及形成在衬底上方的至少一个对准沟槽，每个对准沟槽具有基本上平行于至少一个采样沟槽的纵向轴线的纵向轴线。
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10.发明申请SAMPLE ASSEMBLY WITH AN ELECTROMAGNETIC FIELD TO ACCELERATE THE BONDING OF TARGET ANTIGENS AND NANOPARTICLES 审中-公开具有电磁场的样品组件可以加速目标抗原和纳米颗粒的结合公开(公告)号：US20160274099A1
公开(公告)日：2016-09-22
申请号：US15169340
申请日：2016-05-31
IPC分类号： G01N33/543
CPC分类号： G01N33/54386 , B82Y5/00 , B82Y15/00 , G01N15/1031 , G01N33/54326 , G01N33/54333 , G01N33/54346 , G01N33/54353 , G01N33/54366 , G01N33/54393
摘要： Described are embodiments of an invention for a sample assembly with an electrical conductor for detection of the antigens by electromagnetic read heads. In one embodiment, a sample assembly includes: a substrate; one or more base layers above the substrate; an outer layer above the substrate; a plurality of sample trenches formed in the outer layer, each sample trench being characterized by an upper surface, a bottom surface, and a longitudinal axis; an electrical conductor disposed in the substrate, the electrical conductor being configured to generate an electromagnetic field in proximity to the plurality of sample trenches to enhance nanoparticle movement toward the bottom surface of the plurality of sample trenches; and at least one alignment trench formed above the substrate, each alignment trench having a longitudinal axis substantially parallel to a longitudinal axis of at least one of the sample trenches.
摘要翻译： 描述了用于具有用于通过电磁读取头检测抗原的电导体的样本组件的发明的实施例。 在一个实施例中，样品组件包括：基底; 在基底上方一个或多个基层; 衬底上方的外层; 形成在外层中的多个样品沟槽，每个样品沟槽的特征在于上表面，底表面和纵向轴线; 设置在所述基板中的电导体，所述电导体被配置为在所述多个样品沟槽附近产生电磁场，以增强朝向所述多个样品沟槽的底表面的纳米颗粒运动; 以及形成在衬底上方的至少一个对准沟槽，每个对准沟槽具有基本上平行于至少一个采样沟槽的纵向轴线的纵向轴线。
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