公开(公告)号：US20090149632A1

公开(公告)日：2009-06-11

申请号：US12148094

申请日：2008-04-16

申请人： Isao Nagaoka ,  Daiju Okuda ,  Shin Yomogida ,  Hiroshi Tamura

发明人： Isao Nagaoka ,  Daiju Okuda ,  Shin Yomogida ,  Hiroshi Tamura

IPC分类号： C07K7/00 ,  C07K1/00

CPC分类号： C07K14/4723

摘要： The present invention provides a novel peptide based on CAP11 as well as provides an antibacterial agent, an LPS-cell-binding inhibitor, and a drug such as a bacterial-infection-treating agent or an endotoxin-shock suppressant, each containing the peptide as an active ingredient. The peptide has the following amino acid sequence (SEQ ID NO: 1): X01 X02 X03 X03 X04 X02 X03 X03 X05 X04 X03 X04 X02 X01 X03 X02 X05 X03 (wherein X01 represents a cationic amino acid residue or a polar uncharged amino acid residue, X02 represents a non-polar amino acid residue, X03 represents a cationic amino acid residue, X04 represents a non-polar amino acid residue or a cationic amino acid residue, and X05 represents a non-polar amino acid residue or a polar uncharged amino acid residue). Each of the antibacterial agent, lipopolysaccharide-cell-binding inhibitor, and drug (e.g., bacterial-infection-treating agent or endotoxin-shock suppressant) contains the peptide as an active ingredient. The present invention also provides for a peptide comprised of a sequence of cationic and non-polar or polar uncharged amino acids forming an α-helix wherein the amino acids are arranged along the α-helix such that when represented as a helical wheel, there is a substantial bi-lateral symmetry between cationic versus non-polar or polar uncharged amino acids.

摘要翻译： 本发明提供了一种基于CAP11的新型肽，并且提供了抗细菌剂，LPS-细胞结合抑制剂和细菌感染处理剂或内毒素 - 休克抑制剂等药物，每种含有肽作为 活性成分。 肽具有以下氨基酸序列（SEQ ID NO：1）：X01 X02 X03 X03 X04 X02 X03 X03 X05 X04 X03 X04 X02 X01 X03 X02 X05 X03（其中X01表示阳离子性氨基酸残基或极性不带电荷的氨基酸残基 X02表示非极性氨基酸残基，X03表示阳离子性氨基酸残基，X04表示非极性氨基酸残基或阳离子性氨基酸残基，X05表示非极性氨基酸残基或极性不带电氨基 酸残基）。 各抗菌剂，脂多糖 - 细胞结合抑制剂和药物（例如细菌感染处理剂或内毒素 - 休克抑制剂）均含有作为有效成分的肽。 本发明还提供了由阳离子和非极性或极性不带电荷的氨基酸序列组成的肽，其形成α-螺旋，其中氨基酸沿着α-螺旋排列，使得当以螺旋轮表示时，存在 阳离子与非极性或极性不带电氨基酸之间的实质双侧对称性。

公开(公告)号：US08242082B2

公开(公告)日：2012-08-14

申请号：US12148094

申请日：2008-04-16

申请人： Isao Nagaoka ,  Daiju Okuda ,  Shin Yomogida ,  Hiroshi Tamura

发明人： Isao Nagaoka ,  Daiju Okuda ,  Shin Yomogida ,  Hiroshi Tamura

IPC分类号： A61K38/10

CPC分类号： C07K14/4723

摘要： The present invention provides a novel peptide based on CAP11 as well as provides an antibacterial agent, an LPS-cell-binding inhibitor, and a drug such as a bacterial-infection-treating agent or an endotoxin-shock suppressant, each containing the peptide as an active ingredient. The peptide has the following amino acid sequence (SEQ ID NO: 1): X01 X02 X03 X03 X04 X02 X03 X03 X05 X04 X03 X04 X02 X01 X03 X02 X05 X03 (wherein X01 represents a cationic amino acid residue or a polar uncharged amino acid residue, X02 represents a non-polar amino acid residue, X03 represents a cationic amino acid residue, X04 represents a non-polar amino acid residue or a cationic amino acid residue, and X05 represents a non-polar amino acid residue or a polar uncharged amino acid residue). Each of the antibacterial agent, lipopolysaccharide-cell-binding inhibitor, and drug (e.g., bacterial-infection-treating agent or endotoxin-shock suppressant) contains the peptide as an active ingredient. The present invention also provides for a peptide comprised of a sequence of cationic and non-polar or polar uncharged amino acids forming an α-helix wherein the amino acids are arranged along the α-helix such that when represented as a helical wheel, there is a substantial bi-lateral symmetry between cationic versus non-polar or polar uncharged amino acids.

摘要翻译： 本发明提供了一种基于CAP11的新型肽，并且提供了抗细菌剂，LPS-细胞结合抑制剂和细菌感染处理剂或内毒素 - 休克抑制剂等药物，每种含有肽作为 活性成分。 肽具有以下氨基酸序列（SEQ ID NO：1）：X01 X02 X03 X03 X04 X02 X03 X03 X05 X04 X03 X04 X02 X01 X03 X02 X05 X03（其中X01表示阳离子性氨基酸残基或极性不带电荷的氨基酸残基 X02表示非极性氨基酸残基，X03表示阳离子性氨基酸残基，X04表示非极性氨基酸残基或阳离子性氨基酸残基，X05表示非极性氨基酸残基或极性不带电氨基 酸残基）。 各抗菌剂，脂多糖 - 细胞结合抑制剂和药物（例如细菌感染处理剂或内毒素 - 休克抑制剂）均含有作为有效成分的肽。 本发明还提供了由阳离子和非极性或极性不带电荷的氨基酸序列组成的肽，其形成α-螺旋，其中氨基酸沿α螺旋排列，使得当以螺旋轮表示时，存在 阳离子与非极性或极性不带电氨基酸之间的实质双侧对称性。

公开(公告)号：US20060009374A1

公开(公告)日：2006-01-12

申请号：US11093875

申请日：2005-03-29

申请人： Isao Nagaoka ,  Daiju Okuda ,  Shin Yomogida ,  Hiroshi Tamura

发明人： Isao Nagaoka ,  Daiju Okuda ,  Shin Yomogida ,  Hiroshi Tamura

IPC分类号： A61K38/16 ,  C07K14/195

CPC分类号： C07K14/4723

摘要： The present invention provides a novel peptide based on CAP11 as well as provides an antibacterial agent, an LPS-cell-binding inhibitor, and a drug such as a bacterial-infection-treating agent or an endotoxin-shock suppressant, each containing the peptide as an active ingredient. The peptide has the following amino acid sequence (SEQ ID NO: 1): X01 X02 X03 X03 X04 X02 X03 X03 X05 X04 X03 X04 X02 X01 X03 X02 X05 X03 (wherein X01 represents a cationic amino acid residue or a polar uncharged amino acid residue, X02 represents a non-polar amino acid residue, X03 represents a cationic amino acid residue, X04 represents a non-polar amino acid residue or a cationic amino acid residue, and X05 represents a non-polar amino acid residue or a polar uncharged amino acid residue). Each of the antibacterial agent, lipopolysaccharide-cell-binding inhibitor, and drug (e.g., bacterial-infection-treating agent or endotoxin-shock suppressant) contains the peptide as an active ingredient. The present invention also provides for a peptide comprised of a sequence of cationic and non-polar or polar uncharged amino acids forming an α-helix wherein the amino acids are arranged along the α-helix such that when represented as a helical wheel, there is a substantial bi-lateral symmetry between cationic versus non-polar or polar uncharged amino acids.

公开(公告)号：US07452856B2

公开(公告)日：2008-11-18

申请号：US11093875

申请日：2005-03-29

申请人： Isao Nagaoka ,  Daiju Okuda ,  Shin Yomogida ,  Hiroshi Tamura

发明人： Isao Nagaoka ,  Daiju Okuda ,  Shin Yomogida ,  Hiroshi Tamura

IPC分类号： A61K38/00 ,  C07K17/00

CPC分类号： C07K14/4723

摘要： The present invention provides a novel peptide based on CAP11 as well as provides an antibacterial agent, an LPS-cell-binding inhibitor, and a drug such as a bacterial-infection-treating agent or an endotoxin-shock suppressant, each containing the peptide as an active ingredient. The peptide has the following amino acid sequence (SEQ ID NO: 1): X01 X02 X03 X03 X04 X02 X03 X03 X05 X04 X03 X04 X02 X01 X03 X02 X05 X03 (wherein X01 represents a cationic amino acid residue or a polar uncharged amino acid residue, X02 represents a non-polar amino acid residue, X03 represents a cationic amino acid residue, X04 represents a non-polar amino acid residue or a cationic amino acid residue, and X05 represents a non-polar amino acid residue or a polar uncharged amino acid residue). Each of the antibacterial agent, lipopolysaccharide-cell-binding inhibitor, and drug (e.g., bacterial-infection-treating agent or endotoxin-shock suppressant) contains the peptide as an active ingredient. The present invention also provides for a peptide comprised of a sequence of cationic and non-polar or polar uncharged amino acids forming an α-helix wherein the amino acids are arranged along the α-helix such that when represented as a helical wheel, there is a substantial bi-lateral symmetry between cationic versus non-polar or polar uncharged amino acids.

摘要翻译： 本发明提供了一种基于CAP11的新型肽，并且提供了抗细菌剂，LPS-细胞结合抑制剂和细菌感染处理剂或内毒素 - 休克抑制剂等药物，每种含有肽作为 活性成分。 肽具有以下氨基酸序列（SEQ ID NO：1）：X01 X02 X03 X03 X04 X02 X03 X03 X05 X04 X03 X04 X02 X01 X03 X02 X05 X03（其中X01表示阳离子性氨基酸残基或极性不带电荷的氨基酸残基 X02表示非极性氨基酸残基，X03表示阳离子性氨基酸残基，X04表示非极性氨基酸残基或阳离子性氨基酸残基，X05表示非极性氨基酸残基或极性不带电氨基 酸残基）。 各抗菌剂，脂多糖 - 细胞结合抑制剂和药物（例如细菌感染处理剂或内毒素 - 休克抑制剂）均含有作为有效成分的肽。 本发明还提供了由阳离子和非极性或极性不带电荷的氨基酸序列组成的肽，其形成α-螺旋，其中氨基酸沿着α-螺旋排列，使得当以螺旋轮表示时，存在 阳离子与非极性或极性不带电氨基酸之间的实质双侧对称性。

公开(公告)号：US20140167662A1

公开(公告)日：2014-06-19

申请号：US14234455

申请日：2012-07-25

申请人： Toshiyuki Ajima ,  Hiroyuki Yamada ,  Hiroshi Tamura ,  Kimihisa Furukawa

发明人： Toshiyuki Ajima ,  Hiroyuki Yamada ,  Hiroshi Tamura ,  Kimihisa Furukawa

IPC分类号： H02P6/16

CPC分类号： H02P6/16 ,  H02P6/182 ,  H02P21/18

摘要： An inverter device that controls a motor using a signal from a position sensor for detecting a rotor rotational position of the motor includes an initial adjustment unit that outputs a phase of current for designating a motor rotational position by rotating the motor in a clockwise direction of the motor and a phase of current for designating the motor rotational position by rotating the motor in a counter-clockwise direction of the motor.

摘要翻译： 使用来自用于检测电动机的转子旋转位置的位置传感器的信号来控制电动机的逆变器装置包括初始调整单元，其通过使电动机沿着顺时针方向旋转来输出用于指定电动机旋转位置的电流的相位 电动机和用于通过沿电动机的逆时针方向旋转电动机来指定电动机旋转位置的电流相位。

公开(公告)号：US08688315B2

公开(公告)日：2014-04-01

申请号：US13513221

申请日：2010-11-15

申请人： Hiroshi Tamura

发明人： Hiroshi Tamura

IPC分类号： G01M17/00

CPC分类号： G06F17/5009 ,  G06F17/5018 ,  G06F17/5095 ,  G06F2217/16 ,  G06F2217/80 ,  Y02T10/82

摘要： A first analyzing step is a step that conducts numerical analysis of a flow field but does not conduct numerical analysis of a temperature field in a state in which a motor rotor is rotating. The second analyzing step is a step that conducts numerical analysis of both the flow field and the temperature field after the first analyzing step ends. Accordingly, before numerical analysis of the flow field and numerical analysis of the temperature field are conducted together, numerical analysis is conducted first on the flow field in first analyzing step before it is conducted on the temperature field. As a result, compared with when the second analyzing step is executed from the beginning without conducting the first analyzing step, the calculation load of the numerical analysis on an electronic calculator can be reduced, which enables the time that it takes to conduct the numerical analysis to be shortened.

摘要翻译： 第一分析步骤是在电动机转子旋转的状态下进行流场的数值分析但不进行温度场的数值分析的步骤。 第二分析步骤是在第一分析步骤结束之后进行流场和温度场的数值分析的步骤。 因此，在对温度场进行数值分析和温度场数值分析之前，首先对温度场进行第一分析步骤的流场进行数值分析。 结果，与第一分析步骤相比，从第一分析步骤开始执行时，可以减少电子计算器上的数值分析的计算负担，从而能够进行数值分析所需的时间 缩短。

公开(公告)号：US08553257B2

公开(公告)日：2013-10-08

申请号：US12706428

申请日：2010-02-16

申请人： Hiroshi Tamura

发明人： Hiroshi Tamura

IPC分类号： G06F15/00

CPC分类号： G06F9/4411 ,  G06F3/1204 ,  G06F3/1225 ,  G06F3/1285 ,  H04N1/00222 ,  H04N1/00912 ,  H04N2201/0015 ,  H04N2201/0082 ,  H04N2201/0094

摘要： A communication device is driven by an on-demand driver installed in an apparatus that includes an on-demand driver generating program that generates the on-demand driver for the communication device based on device information of the communication device. The communication device includes a memory unit that stores therein the device information of the communication device, a responding unit that, in response to a request for obtaining the device information from the on-demand driver generating program, sends the device information stored in the memory unit to the apparatus, and an updating unit that is used in externally updating the device information stored in the memory unit.

摘要翻译： 通信装置由安装在装置中的点播驱动器驱动，该装置包括基于通信装置的设备信息生成通信装置的按需驱动程序的按需驱动程序生成程序。 通信装置包括：存储单元，存储通信装置的设备信息;响应单元，响应于从点播驱动程序生成程序获取设备信息的请求，发送存储在存储器中的设备信息 单元，以及更新单元，其用于外部更新存储在存储单元中的设备信息。

公开(公告)号：US08269462B2

公开(公告)日：2012-09-18

申请号：US12845063

申请日：2010-07-28

申请人： Hiroyoshi Yamamoto ,  Hiroshi Tamura

发明人： Hiroyoshi Yamamoto ,  Hiroshi Tamura

IPC分类号： H02J7/00 ,  H02J9/00 ,  H01M10/34 ,  G01N27/416

CPC分类号： G01R31/3658 ,  B60L11/1864 ,  B60L11/1866 ,  G01R31/362 ,  G01R31/3624 ,  H01M10/441 ,  H01M10/482 ,  Y02T10/7005 ,  Y02T10/7061 ,  Y10T307/625

摘要： The state monitoring apparatus includes a high-voltage side monitoring section having monitoring units assigned to respective unit batteries and a low-voltage side monitoring section having a control device. The monitoring units measures the voltages of the unit batteries upon reception of a voltage measurement command transmitted from the control device, and determines whether or not the measured voltages are within a predetermined range. This determination is transmitted to the control device. If this determination is negative, the control device limits a charge/discharge current of the assembled battery, and then causes the monitoring units to transmit the measured voltages.

摘要翻译： 状态监视装置包括具有分配给各单元电池的监视单元的高压侧监视部和具有控制装置的低压侧监视部。 监视单元在接收到从控制装置发送的电压测量命令时测量单元电池的电压，并且确定测量的电压是否在预定范围内。 该确定被发送到控制装置。 如果该判定为负，则控制装置限制组电池的充放电电流，然后使监测部发送测定的电压。

公开(公告)号：US07972502B2

公开(公告)日：2011-07-05

申请号：US12166383

申请日：2008-07-02

申请人： Masahiko Tsutsumi ,  Takumi Obara ,  Nobuyuki Ashikaga ,  Katsuya Yamamoto ,  Hiroshi Tamura

发明人： Masahiko Tsutsumi ,  Takumi Obara ,  Nobuyuki Ashikaga ,  Katsuya Yamamoto ,  Hiroshi Tamura

IPC分类号： C02F3/30

CPC分类号： C02F3/30 ,  C02F3/04 ,  C02F3/103 ,  C02F3/2806 ,  C02F3/2846 ,  Y02W10/15 ,  Y10S210/903

摘要： An aeration-less water treatment apparatus including an anaerobic reactor which receives sewage to cause the sewage to flow as an upward stream, and an aerobic reactor which receives treated water from the anaerobic reactor to cause the water to flow as a downward stream so that the water contacts aerobic microorganisms and air to aerobically treat the polluted matter in the water, the apparatus further including a suspended sludge section located in a lower part of the anaerobic reactor and in which the anaerobic microorganisms are suspended in the sewage, and a carrier section located in an upper part of the anaerobic reactor and having carriers to which the anaerobic microorganisms are attached, the anaerobic microorganisms having flowed from the suspended sludge section being further attached to the carriers.

摘要翻译： 一种无曝气水处理装置，包括接收污水以使污水以向上流动的厌氧反应器;以及需氧反应器，其接收来自厌氧反应器的处理水，使水以向下流动的方式流动， 水接触有氧微生物和空气以对水中的污染物质进行有氧处理，该装置还包括位于厌氧反应器下部的悬浮污泥部分，其中厌氧微生物悬浮在污水中，并且载体部分位于 在厌氧反应器的上部并具有附着有厌氧微生物的载体的情况下，从悬浮污泥部分流出的厌氧微生物进一步附着于载体上。

公开(公告)号：US07869913B2

公开(公告)日：2011-01-11

申请号：US11819430

申请日：2007-06-27

申请人： Kiyoshi Aoyama ,  Hiroshi Tamura ,  Akira Kato

发明人： Kiyoshi Aoyama ,  Hiroshi Tamura ,  Akira Kato

IPC分类号： B60K6/24 ,  B60K6/28

CPC分类号： H02J7/1438 ,  B60W2510/244 ,  H02J7/1423 ,  H02J7/1446 ,  H02P9/02 ,  H02P9/48 ,  Y02T10/7005 ,  Y02T10/92 ,  Y10S903/905 ,  Y10S903/93

摘要： A vehicle power supply apparatus has first and second engine-driven electrical generators and first and second storage batteries, the first generator supplying a stable voltage to the first battery and a first set of loads, and the second generator supplying the second battery and a second set of loads, which can tolerate supply voltage variations. Operation of the second generator and charging/discharging of the second battery are controlled to maintain the total engine torque applied to the generators at a level whereby fuel consumption is reduced, while the supply voltage of the variation-tolerant loads is allowed to vary substantially.

摘要翻译： 车辆供电装置具有第一和第二发动机驱动的发电机和第一和第二蓄电池，第一发电机向第一电池供应稳定的电压和第一组负载，第二发电机提供第二电池和第二发电机 一组负载，可以容忍电源电压变化。 控制第二发电机的运转和第二电池的充电/放电，以保持施加到发电机的总发动机扭矩处于降低燃料消耗的水平，同时允许容许变化的负载的电源电压发生显着变化。