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公开(公告)号:US09944589B2
公开(公告)日:2018-04-17
申请号:US14650292
申请日:2013-12-03
发明人: Mario Varasi , Paola Vianello , Florian Thaler , Paolo Trifiro′ , Ciro Mercurio , Giuseppe Meroni
IPC分类号: C07C211/40 , A61K31/4025 , A61K31/404 , A61K31/4164 , A61K31/496 , C07D215/12 , C07D295/195 , C07D207/50 , C07D213/61 , C07D311/70 , C07D211/58 , C07D263/04 , C07D233/02 , C07D271/113 , C07C209/00 , C07C231/12 , C07C269/06 , C07C303/36 , C07D319/16 , C07D233/32 , C07D239/42 , C07D249/06 , C07D263/22 , C07D271/10 , C07D295/155 , C07D213/64 , C07D307/54 , C07C271/28 , C07C211/49 , C07C215/42 , C07C217/58 , C07C217/74 , C07C233/44 , C07C233/80 , C07C237/06 , C07C247/16 , C07C311/21
CPC分类号: C07C211/40 , A61K31/4025 , A61K31/404 , A61K31/4164 , A61K31/496 , C07C209/00 , C07C211/49 , C07C215/42 , C07C217/58 , C07C217/74 , C07C231/12 , C07C233/44 , C07C233/80 , C07C237/06 , C07C247/16 , C07C269/06 , C07C271/28 , C07C303/36 , C07C311/21 , C07C2601/02 , C07D207/50 , C07D211/58 , C07D213/61 , C07D213/64 , C07D215/12 , C07D233/02 , C07D233/32 , C07D239/42 , C07D249/06 , C07D263/04 , C07D263/22 , C07D271/10 , C07D271/113 , C07D295/155 , C07D295/195 , C07D307/54 , C07D311/70 , C07D319/16 , A61K2300/00
摘要: The present invention relates to cyclopropyl derivatives of general formula (I), wherein A, R1, and R2 are as defined in the specification. The present application also relates to pharmaceutical compositions containing such compounds and to their use in therapy.