利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

29 条记录 (耗时 0.034 秒)

    Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins
    1.
    发明授权
    Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins 有权
    有机金属钌络合物及制备四取代的和其他受阻烯烃的相关方法

    公开(公告)号：US08008224B2

    公开(公告)日：2011-08-30

    申请号：US11640400

    申请日：2006-12-18

    申请人： Jacob Berlin ,  Robert H. Grubbs ,  Yann Schrodi ,  Ian C. Stewart

    发明人： Jacob Berlin ,  Robert H. Grubbs ,  Yann Schrodi ,  Ian C. Stewart

    IPC分类号： B01J31/00 ,  C07F17/02

    CPC分类号： C07F15/0046 ,  B01J31/2265 ,  B01J31/2404 ,  B01J2231/543 ,  B01J2531/821 ,  C08G61/08

    摘要： The invention relates to ruthenium alkylidene complexes having an N-heterocyclic carbene ligand comprising a 5-membered heterocyclic ring having a carbenic carbon atom and at least one nitrogen atom contained within the 5-membered heterocyclic ring, wherein the nitrogen atom is directly attached to the carbenic carbon atom and is substituted by a phenyl ring, and wherein the phenyl ring has a hydrogen at either or both ortho positions and is substituted at at least one ortho or meta position. The invention also relates to an olefin metathesis reactions and particularly to the preparation of tetra-substituted cyclic olefins via a ring-closing metathesis.

    摘要翻译： 本发明涉及具有N-杂环卡宾配位体的钌亚烷基配合物，其包括具有碳原子数为5元的五元杂环和至少一个含有5元杂环的氮原子，其中氮原子直接连接到 碳原子并被苯环取代，并且其中苯环在一个或两个邻位具有氢，并且在至少一个邻位或间位取代。 本发明还涉及烯烃复分解反应，特别涉及通过闭环复分解制备四取代环烯烃。

    Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins
    2.
    发明授权
    Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins 有权
    有机金属钌络合物及制备四取代的和其他受阻烯烃的相关方法

    公开(公告)号：US08361922B2

    公开(公告)日：2013-01-29

    申请号：US13221871

    申请日：2011-08-30

    申请人： Jacob Berlin ,  Robert H. Grubbs ,  Yann Schrodi ,  Ian C. Stewart

    发明人： Jacob Berlin ,  Robert H. Grubbs ,  Yann Schrodi ,  Ian C. Stewart

    IPC分类号： B01J31/00 ,  C07F17/02

    CPC分类号： C07F15/0046 ,  B01J31/2265 ,  B01J31/2404 ,  B01J2231/543 ,  B01J2531/821 ,  C08G61/08

    摘要： The invention relates to ruthenium alkylidene complexes having an N-heterocyclic carbene ligand comprising a 5-membered heterocyclic ring having a carbenic carbon atom and at least one nitrogen atom contained within the 5-membered heterocyclic ring, wherein the nitrogen atom is directly attached to the carbenic carbon atom and is substituted by a phenyl ring, and wherein the phenyl ring has a hydrogen at either or both ortho positions and is substituted at at least one ortho or meta position. The invention also relates to an olefin metathesis reactions and particularly to the preparation of tetra-substituted cyclic olefins via a ring-closing metathesis.

    摘要翻译： 本发明涉及具有N-杂环卡宾配位体的钌亚烷基配合物，其包括具有碳原子数为5元的五元杂环和至少一个含有5元杂环的氮原子，其中氮原子直接连接到 碳原子并被苯环取代，并且其中苯环在一个或两个邻位具有氢，并且在至少一个邻位或间位取代。 本发明还涉及烯烃复分解反应，特别涉及通过闭环复分解制备四取代环烯烃。

    Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins
    3.
    发明申请
    Organometallic ruthenium complexes and related methods for the preparation of tetra-substituted and other hindered olefins 有权
    有机金属钌络合物及制备四取代的和其他受阻烯烃的相关方法

    公开(公告)号：US20070282148A1

    公开(公告)日：2007-12-06

    申请号：US11640400

    申请日：2006-12-18

    申请人： Jacob Berlin ,  Robert Grubbs ,  Yann Schrodi ,  Ian Stewart

    发明人： Jacob Berlin ,  Robert Grubbs ,  Yann Schrodi ,  Ian Stewart

    IPC分类号： C07F15/00 ,  C07C6/02 ,  C07D213/02 ,  C07D233/02

    CPC分类号： C07F15/0046 ,  B01J31/2265 ,  B01J31/2404 ,  B01J2231/543 ,  B01J2531/821 ,  C08G61/08

    摘要： The invention relates to ruthenium alkylidene complexes having an N-heterocyclic carbene ligand comprising a 5-membered heterocyclic ring having a carbenic carbon atom and at least one nitrogen atom contained within the 5-membered heterocyclic ring, wherein the nitrogen atom is directly attached to the carbenic carbon atom and is substituted by a phenyl ring, and wherein the phenyl ring has a hydrogen at either or both ortho positions and is substituted at at least one ortho or meta position. The invention also relates to an olefin metathesis reactions and particularly to the preparation of tetra-substituted cyclic olefins via a ring-closing metathesis.

    摘要翻译： 本发明涉及具有N-杂环卡宾配位体的钌亚烷基配合物，其包括具有碳原子数为5元的五元杂环和至少一个含有5元杂环的氮原子，其中氮原子直接连接到 碳原子并被苯环取代，并且其中苯环在一个或两个邻位具有氢，并且在至少一个邻位或间位取代。 本发明还涉及烯烃复分解反应，特别涉及通过闭环复分解制备四取代环烯烃。

    Chelating Carbene Ligand Precursors and Their Use in the Synthesis of Metathesis Catalysts
    8.
    发明申请
    Chelating Carbene Ligand Precursors and Their Use in the Synthesis of Metathesis Catalysts 审中-公开
    螯合碳烯配体前体及其在复分解催化剂合成中的应用

    公开(公告)号：US20150018559A1

    公开(公告)日：2015-01-15

    申请号：US14272859

    申请日：2014-05-08

    申请人： Richard L. Pederson ,  Jason K. Woertink ,  Christopher M. Haar ,  David E. Gindelberger ,  Yann Schrodi

    发明人： Richard L. Pederson ,  Jason K. Woertink ,  Christopher M. Haar ,  David E. Gindelberger ,  Yann Schrodi

    IPC分类号： B01J31/24 ,  C07F15/00

    CPC分类号： B01J31/2414 ,  B01J31/1805 ,  B01J31/2204 ,  B01J31/2208 ,  B01J31/2265 ,  B01J31/2273 ,  B01J31/2278 ,  B01J31/2404 ,  B01J2231/50 ,  B01J2231/54 ,  B01J2231/543 ,  B01J2531/821 ,  B01J2531/825 ,  C07F15/002 ,  C07F15/0046

    摘要： Chelating ligand precursors for the preparation of olefin methathesis catalysts are disclosed. The resulting catalysts are air stable monomeric species capable of promoting various methathesis reactions efficiently, which can be recovered from the reaction mixture and reused. Internal olefin compounds, specifically beta-substituted styrenes, are used as ligand precursors. Compared to terminal olefin compounds such as unsubstituted styrenes, the beta-substituted styrenes are easier and less costly to prepare, and more stable since they are less prone to spontaneous polymerization. Methods of preparing chelating-carbene methathesis catalysts without the use of CuCl are disclosed. This eliminates the need for CuCl by replacing it with organic acids, mineral acids, mild oxidants or even water, resulting in high yields of Hoveyda-type methathesis catalysts. The invention provides an efficient method for preparing chelating-carbene metathesis catalysts by reacting a suitable ruthenium complex in high concentrations of the ligand precursors followed by crystallization from an organic solvent.

    摘要翻译： 公开了用于制备烯烃复合催化剂的螯合配体前体。 得到的催化剂是能够有效促进各种复合反应的空气稳定的单体物质，其可以从反应混合物中回收并重复使用。 使用内部烯烃化合物，特别是β-取代的苯乙烯作为配体前体。 与末端烯烃化合物如未取代的苯乙烯相比，β-取代的苯乙烯更容易制备成本更低，更稳定，因为它们不易于自发聚合。 公开了不使用CuCl制备螯合 - 卡宾络合催化剂的方法。 这通过用有机酸，无机酸，温和氧化剂甚至水代替它来消除对CuCl的需要，导致Hoveyda型复分解催化剂的高产率。 本发明提供了一种制备螯合碳烯复分解催化剂的有效方法，该方法是通过在高浓度配体前体中合适的钌络合物，然后从有机溶剂中结晶而制备。

    Chelating carbene ligand precursors and their use in the synthesis of metathesis catalysts
    10.
    发明授权
    Chelating carbene ligand precursors and their use in the synthesis of metathesis catalysts 有权
    螯合卡宾配体前体及其在复分解催化剂合成中的应用

    公开(公告)号：US07268242B2

    公开(公告)日：2007-09-11

    申请号：US11344637

    申请日：2006-01-31

    申请人： Richard L. Pederson ,  Jason K. Woertink ,  Christopher M. Haar ,  David E. Gindelberger ,  Yann Schrodi

    发明人： Richard L. Pederson ,  Jason K. Woertink ,  Christopher M. Haar ,  David E. Gindelberger ,  Yann Schrodi

    IPC分类号： C07F15/00 ,  C07F9/02 ,  C07C39/00

    CPC分类号： B01J31/2414 ,  B01J31/1805 ,  B01J31/2204 ,  B01J31/2208 ,  B01J31/2265 ,  B01J31/2273 ,  B01J31/2278 ,  B01J31/2404 ,  B01J2231/50 ,  B01J2231/54 ,  B01J2231/543 ,  B01J2531/821 ,  B01J2531/825 ,  C07F15/002 ,  C07F15/0046

    摘要： Chelating ligand precursors for the preparation of olefin metathesis catalysts are disclosed. The resulting catalysts are air stable monomeric species capable of promoting various metathesis reactions efficiently, which can be recovered from the reaction mixture and reused. Internal olefin compounds, specifically beta-substituted styrenes, are used as ligand precursors. Compared to terminal olefin compounds such as unsubstituted styrenes, the beta-substituted styrenes are easier and less costly to prepare, and more stable since they are less prone to spontaneous polymerization. Methods of preparing chelating-carbene metathesis catalysts without the use of CuCl are disclosed. This eliminates the need for CuCl by replacing it with organic acids, mineral acids, mild oxidants or even water, resulting in high yields of Hoveyda-type metathesis catalysts. The invention provides an efficient method for preparing chelating-carbene metathesis catalysts by reacting a suitable ruthenium complex in high concentrations of the ligand precursors followed by crystallization from an organic solvent.

    摘要翻译： 公开了用于制备烯烃复分解催化剂的螯合配体前体。 所得催化剂是能够有效促进各种复分解反应的空气稳定的单体物质，其可以从反应混合物中回收并重复使用。 使用内部烯烃化合物，特别是β-取代的苯乙烯作为配体前体。 与末端烯烃化合物如未取代的苯乙烯相比，β-取代的苯乙烯更容易制备成本更低，更稳定，因为它们不易于自发聚合。 公开了不使用CuCl制备螯合 - 碳烯复分解催化剂的方法。 这通过用有机酸，无机酸，温和氧化剂甚至水代替它来消除对CuCl的需要，导致Hoveyda型复分解催化剂的高产率。 本发明提供了一种制备螯合碳烯复分解催化剂的有效方法，该方法是通过在高浓度配体前体中合适的钌络合物，然后从有机溶剂中结晶而制备。