利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

11 条记录 (耗时 0.035 秒)

    ASSAY FOR IDENTIFYING INHIBITORS OF NEURONAL APOPTOTIC PATHWAYS
    4.
    发明申请
    ASSAY FOR IDENTIFYING INHIBITORS OF NEURONAL APOPTOTIC PATHWAYS 审中-公开
    用于鉴定神经病毒途径的抑制剂的测定

    公开(公告)号：US20090179638A1

    公开(公告)日：2009-07-16

    申请号：US12278071

    申请日：2007-02-01

    申请人： Philip A. Barker ,  James B. Jaquith ,  Stephen J. Morris ,  Amir Salehi

    发明人： Philip A. Barker ,  James B. Jaquith ,  Stephen J. Morris ,  Amir Salehi

    IPC分类号： G01V3/00 ,  C07D513/04 ,  C07F5/02 ,  G01N33/68 ,  G01N33/566

    CPC分类号： G01N33/6896 ,  G01N2500/02

    摘要： Disclosed is an assay for identifying compounds that modulate a neuronal apoptotic pathway, the assay comprises: a) contacting HSP90 protein with a probe to form a probe: HSP90 complex, the probe being displaceable by a test compound; b) measuring a signal from the probe so as to establish a reference level; c) incubating the probe:HSP90 complex with the test compound; d) measuring the signal from the probe; e) comparing the signal from step d) with the reference level, a modulation of the signal indicating that the test compound binds to HSP90. Also disclosed is a probe which is labeled with a detectable label and/or an affinity tag.

    摘要翻译： 公开了用于鉴定调节神经元凋亡途径的化合物的测定法，该测定包括：a）使HSP90蛋白与探针接触以形成探针：HSP90复合物，所述探针可被测试化合物置换; b）测量来自探针的信号，以便建立参考水平; c）将探针：HSP90复合物与测试化合物孵育; d）测量探头的信号; e）将来自步骤d）的信号与参考水平进行比较，指示测试化合物与HSP90结合的信号的调制。 还公开了用可检测标记和/或亲和标签标记的探针。

    Mechanism for removing heat from electronic components
    5.
    发明授权
    Mechanism for removing heat from electronic components 失效
    从电子部件去除热量的机构

    公开(公告)号：US6081424A

    公开(公告)日：2000-06-27

    申请号：US81378

    申请日：1998-05-19

    申请人： Terry P. Mach ,  Kurt R. Jackson ,  Frank Hodges ,  Alfred H. Glover ,  Chandrakant Dave ,  Stephen J. Morris ,  Joseph T. Betterton

    发明人： Terry P. Mach ,  Kurt R. Jackson ,  Frank Hodges ,  Alfred H. Glover ,  Chandrakant Dave ,  Stephen J. Morris ,  Joseph T. Betterton

    IPC分类号： H05K7/20

    CPC分类号： H05K7/20436 ,  H05K7/2049

    摘要： Heat is removed from electronic components located within a closed housing by the use of a heat-conducting metal clip mounted on the housing cover so as to be in pressure contact with the electronic components. The metal clip includes a U-shaped mounting portion firmly clamped to a clip-mounting wall projecting from the cover, and a series of spring arms extending through a slot opening in the cover into pressure contact with individual electronic components. The clamp force of the clip on the mounting wall is designed to act independently of the pressure exerted by each spring arm on an associated electronic component.

    摘要翻译： 通过使用安装在壳体盖上的导热金属夹将热量从位于封闭壳体内的电子部件移除，以与电子部件压力接触。 金属夹包括牢固地夹紧到从盖突出的夹子安装壁的U形安装部分，以及延伸穿过盖中的槽开口的一系列弹簧臂，以与各个电子部件压力接触。 夹子在安装壁上的夹紧力被设计成独立于每个弹簧臂施加在相关电子部件上的压力。

    Web advertising method
    6.
    发明授权
    Web advertising method 失效
    网络广告方式

    公开(公告)号：US08635327B1

    公开(公告)日：2014-01-21

    申请号：US09548235

    申请日：2000-04-12

    申请人： Thomas Mark Levergood ,  Lawrence C. Stewart ,  Stephen J. Morris ,  Andrew C. Payne ,  George W. Treese

    发明人： Thomas Mark Levergood ,  Lawrence C. Stewart ,  Stephen J. Morris ,  Andrew C. Payne ,  George W. Treese

    IPC分类号： G06F15/16

    CPC分类号： H04L63/10

    摘要： Link traversals leading from an advertisement on the Web to a product page are determined. The determined link traversals are used as a basis for charging for advertising, for example, by counting the number of link traversals from the advertising page to a product page, or by counting the number of sales resulting from such traversals. The effectiveness of advertising on the Web is evaluated by measuring the number of sales or transactions resulting from link traversals from the advertisement to the page.

    摘要翻译： 将从Web上的广告引导到产品页面的链接遍历被确定。 确定的链接遍历被用作广告收费的基础，例如通过计算从广告页面到产品页面的链接遍历的数量，或通过计算由这些遍历产生的销售数量。 通过测量从广告到页面的链接遍历导致的销售或交易的数量来评估广告在网络上的有效性。

    Method for determining modifications to semiconductor optical functions
    7.
    发明授权
    Method for determining modifications to semiconductor optical functions 有权
    用于确定对半导体光学功能的修改的方法

    公开(公告)号：US07224461B2

    公开(公告)日：2007-05-29

    申请号：US10847423

    申请日：2004-05-17

    申请人： Stephen J. Morris

    发明人： Stephen J. Morris

    IPC分类号： G01N21/55

    CPC分类号： G01N21/211

    摘要： A method for modeling the complex refractive index of doped, strained or ultra-thin semiconductors starts with a model for a standard bulk material which may be in any form such as a pre-existing lookup table, a dispersion model derived from an effective medium approximation (EMA) or a critical point (CP) model. The modeling method perturbs the ∈2 curve of the bulk material by enhancing, suppressing or shifting the strong features of the curve. A Kramers-Kronig transformation is then applied to the ∈2 perturbation to obtain the corresponding perturbation to the ∈1 curve. The combination of the perturbed ∈2 curve and the correspondingly perturbed ∈1 curve are then used to obtain the complex dielectric function or complex refractive index of the modified material.

    摘要翻译： 用于对掺杂，应变或超薄半导体的复折射率进行建模的方法从用于标准散装材料的模型开始，其可以是任何形式，例如预先存在的查找表，从有效介质近似导出的色散模型 （EMA）或临界点（CP）模型。 该建模方法通过增强，抑制或移动曲线的强特征来扰乱散装材料的∈2 曲线。 然后将Kramers-Kronig变换应用于∈2π扰动，以获得对Λ1 曲线的对应扰动。 然后使用扰动的ζ2曲线和相应的扰动∈1 曲线的组合来获得修饰材料的复合介电函数或复折射率。

    Apparatus and method for positioning a workpiece
    8.
    发明授权
    Apparatus and method for positioning a workpiece 有权
    用于定位工件的装置和方法

    公开(公告)号：US08028427B2

    公开(公告)日：2011-10-04

    申请号：US12594106

    申请日：2008-03-28

    申请人： Stephen J. Morris

    发明人： Stephen J. Morris

    IPC分类号： G01B11/27

    CPC分类号： G01B5/0004

    摘要： A stage for aligning a workpiece relative to analyzing apparatus. The stage has a platform and means for maintaining a workpiece on the platform. The platform is operable to tilt relative to the analyzing apparatus and thereby rotate the workpiece relative to the analyzing apparatus.

    摘要翻译： 用于使工件相对于分析装置对准的台。 该台具有用于在平台上保持工件的平台和装置。 平台可操作以相对于分析装置倾斜，从而相对于分析装置旋转工件。