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公开(公告)号：US4945060A
公开(公告)日：1990-07-31
申请号：US168291
申请日：1988-03-15
摘要： An instrument and a sealable, sterilizable vessel for detecting the presence of microorganisms in a specimen, the vessel containing a liquid culture medium and a sensor means with an indicator medium therein. Changes in the indicator medium resulting from pH change or change in CO.sub.2 concentration in the medium are detected from outside the vessel.
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2.发明授权Device and method for enhanced recovery and detection of microbial growth in the presence of antimicrobial substances 失效在抗菌物质存在下增强微生物生长恢复和检测的装置和方法
公开(公告)号：US5162229A
公开(公告)日：1992-11-10
申请号：US732569
申请日：1991-07-19
申请人： Thurman C. Thorpe , James L. DiGuiseppi , Richard C. Driscoll , James E. Turner , Michael J. Calandra
发明人： Thurman C. Thorpe , James L. DiGuiseppi , Richard C. Driscoll , James E. Turner , Michael J. Calandra
CPC分类号： C12M41/46 , C12M23/22 , C12N1/38 , C12Q1/04 , Y10S435/807 , Y10T436/235
摘要： The present invention relates to a device and method of detecting microorganisms in a rapid manner and increasing the number of microorganisms detected during the culturing of a sample by the addition of resinous and non-resin adsorbents and molecular sieves in the growth media. These agents have been found to neutralize or remove inhibitory and antimicrobial substances found in samples and media.
摘要翻译： 本发明涉及通过在生长培养基中添加树脂和非树脂吸附剂和分子筛，快速检测微生物并增加在培养样品期间检测到的微生物数量的装置和方法。 已经发现这些试剂中和或去除样品和培养基中发现的抑制性和抗微生物物质。
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公开(公告)号：US5217876A
公开(公告)日：1993-06-08
申请号：US866130
申请日：1992-04-07
申请人： James E. Turner , Thurman C. Thorpe , James L. DiGuiseppi , Richard C. Driscoll , Michael J. Calandra
发明人： James E. Turner , Thurman C. Thorpe , James L. DiGuiseppi , Richard C. Driscoll , Michael J. Calandra
IPC分类号： C12M1/34
摘要： An instrument and a sealable, sterilizable vessel for detecting the presence of microorganisms in a specimen, the vessel containing a liquid culture medium and a sensor means with an indicator medium therein. Changes in the indicator medium resulting from pH change or change in CO.sub.2 concentration in the medium are detected from outside the vessel.
摘要翻译： 一种用于检测样品中微生物存在的仪器和可密封的可灭菌容器，所述容器含有液体培养基和其中具有指示剂介质的传感器装置。 从容器外部检测由pH变化引起的指示剂介质的变化或介质中CO 2浓度的变化。
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公开(公告)号：US5094955A
公开(公告)日：1992-03-10
申请号：US480398
申请日：1990-02-15
申请人： Michael J. Calandra , James E. Turner , Thurman C. Thorpe , James L. DiGuiseppi , Richard C. Driscoll , Carmella S. Moody
发明人： Michael J. Calandra , James E. Turner , Thurman C. Thorpe , James L. DiGuiseppi , Richard C. Driscoll , Carmella S. Moody
IPC分类号： C12M1/34 , C12Q1/04 , C12Q1/18 , G01N27/416
CPC分类号： G01N21/80 , C12M23/22 , C12M41/26 , C12M41/34 , C12M41/46 , G01N21/6428 , G01N21/78 , Y10S435/807 , Y10T436/235
摘要： An instrument and a sealable vessel for detecting the presence of microorganisms in a specimen, the vessel containing a liquid culture medium communicating with a sensor means containing an indicator medium therein. Changes in the indicator medium resulting from pH change or change in CO.sub.2 concentration in the medium are detected from outside the vessel.
摘要翻译： 一种用于检测样品中微生物存在的仪器和可密封容器，所述容器含有与其中含有指示剂介质的传感器装置连通的液体培养基。 从容器外部检测由pH变化引起的指示剂介质的变化或介质中CO 2浓度的变化。
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公开(公告)号：US5518895A
公开(公告)日：1996-05-21
申请号：US410374
申请日：1995-03-24
CPC分类号： G01N7/14 , C12M41/26 , C12M41/36 , C12M41/40 , C12M41/46 , G01N21/253 , Y10S435/807 , Y10S73/04
摘要： A device and method for detecting microorganisms in a specimen by culturing the specimen in a sealable specimen container with a culture medium and detecting microorganisms in the specimen-by measuring changes in pressure within the container caused by their metabolic activity during culturing. Pressure changes are measured using a sensor having a deformable section in communication with the container and a piezoelectric apparatus, such that the piezoelectric apparatus is deformed by changes in pressure within the specimen container and an electrical signal is produced by the deformation. The electrical signal is processed to detect any change in the rate of change of pressure, and thus detect the growth of microorganisms.
摘要翻译： 通过用培养基培养样本在可密封的标本容器中并通过测量培养中其代谢活动引起的容器内的压力变化来检测样品中的微生物来检测样品中的微生物的装置和方法。 使用具有与容器和压电装置连通的变形部的传感器来测量压力变化，使得压电装置通过样本容器内的压力变化而变形，并且通过变形产生电信号。 处理电信号以检测压力变化率的任何变化，从而检测微生物的生长。
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公开(公告)号：US5856175A
公开(公告)日：1999-01-05
申请号：US653375
申请日：1996-05-21
CPC分类号： G01N7/14 , C12M41/26 , C12M41/36 , C12M41/40 , C12M41/46 , G01N21/253 , Y10S435/807 , Y10S73/04
摘要： A device and method for detecting microorganisms in a specimen by culturing the specimen in a sealable specimen container with a culture medium and detecting microorganisms in the specimen by measuring changes in pressure within the container caused by their metabolic activity during culturing. Pressure changes are measured using a sensor having a deformable section in communication with the container and a piezoelectric apparatus, such that the piezoelectric apparatus is deformed by changes in pressure within the specimen container and an electrical signal is produced by the deformation. The electrical signal is processed to detect any change in the rate of change of pressure, and thus detect the growth of microorganisms.
摘要翻译： 通过在具有培养基的可密封的标本容器中培养样品并通过测量在培养期间由其代谢活动引起的容器内的压力变化来检测样品中的微生物来检测样品中的微生物的装置和方法。 使用具有与容器和压电装置连通的变形部的传感器来测量压力变化，使得压电装置通过样本容器内的压力变化而变形，并且通过变形产生电信号。 处理电信号以检测压力变化率的任何变化，从而检测微生物的生长。
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公开(公告)号：US4931653A
公开(公告)日：1990-06-05
申请号：US207723
申请日：1988-06-16
IPC分类号： G01T1/29
CPC分类号： G01T1/2935
摘要： An optical ionizing radiation detector system (10) for determining the three-dimensional spatial distribution of all of the secondary electrons produced by the passage of ionizing radiation through a selected gas is provided. The detector system (10) can be used over a wide range of particle energies and gas pressures. The ionizing radiation passing through the gas produces prompt fluorescence and secondary electrons. A coincidence detector (30) recognizes coincident events of prompt fluorescence in the gas contained within that chamber to initialize the system cycle. At that time, an AC electric field is generated by an R.F. pulse generator (40) to localize the secondary electrons proximate their respective positions of production. Cameras (42) and 42'), preferably of a digital type, produce an image of the localized electrons to determine their three-dimensional spatial positions. After such positions are determined, a unidirectional electric field is generated by clearing power supply (36) for clearing all charges from the gas chamber.
摘要翻译： 提供了一种用于确定通过选定气体通过电离辐射产生的所有二次电子的三维空间分布的光电离辐射探测器系统（10）。 检测器系统（10）可以在宽范围的粒子能量和气体压力下使用。 通过气体的电离辐射产生迅速的荧光和二次电子。 符合检测器（30）识别包含在该室内的气体中的快速荧光的重合事件以初始化系统周期。 此时，由R.F.产生交流电场。 脉冲发生器（40），用于将二次电子定位在其相应的生产位置附近。 相机（42）和42'）优选地是数字类型，产生局部电子的图像以确定它们的三维空间位置。 在确定这样的位置之后，通过清除用于从气室清除所有电荷的电源（36）产生单向电场。
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公开(公告)号：US4191522A
公开(公告)日：1980-03-04
申请号：US962872
申请日：1978-11-22
申请人： James E. Turner
发明人： James E. Turner
CPC分类号： B29B17/0042 , B29C47/0016 , B29C47/54 , B29C47/8805 , B29C47/8895 , B29C47/003 , B29C47/0033 , B29K2021/00 , B29K2105/04 , B29L2030/00 , Y02W30/62
摘要： A molding apparatus, using raw material substantially comprised of crumbed rubber tires, and producing end products of durability and structural integrity. Products such as fence posts and dimensioned pieces like dimension-lumber products, have a hardened, dense outer wall structure surrounding a comparatively less dense and relatively porous central core, with the attendent structure integrity advantages of tubular and hollow-walled products. Heat fused raw material is fed under pressure, as from a screw extruder mechanism, through selectively controlled input valves to mold bodies, with the mold bodies carried in a chilled environment to establish fluid flow paths and hardening sequences leading to the desired end product body structure.
摘要翻译： 一种成型设备，使用基本上由碎屑橡胶轮胎组成的原料，并生产耐久性和结构完整性的最终产品。 诸如围栏柱和尺寸尺寸的产品如尺寸木材产品具有围绕相对较不致密且相对多孔的中心芯的硬化，致密的外壁结构，并且具有管状和中空壁产品的出人意料的结构完整性优点。 热熔原料在压力下通过螺杆挤出机构通过选择性控制的输入阀进入模具体，模具体在冷冻环境中运送，以建立流体流动路径和硬化顺序，从而导致所需的最终产品体结构 。
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公开(公告)号：US3949718A
公开(公告)日：1976-04-13
申请号：US471865
申请日：1974-05-21
申请人： James E. Turner
发明人： James E. Turner
摘要： A corona coupling system with a plurality of corona coupling unit blocks, individually snapped on spark plug wires and coil wires, interconnected by wire for corona coupling distribution between the spark plug and coil wires. The blocks are interconnected by two generally parallel, insulated wires clamped in place running through each two-piece block by a stamped conductive metal plate having formed-down corners biting into and through insulation on the block interconnecting wires as plastic top and bottom parts of each block are pressed and sonically welded together. The stamped conductive metal plate is formed with a downward longitudinally extended ridge positioned in the blocks so that the bottom edge rests against and along the insulation of the wire on which each block is mounted.
摘要翻译： 具有多个电晕耦合单元块的电晕耦合系统，单独地接在火花塞线和线圈线上，用电线互连，用于火花塞和线圈线之间的电晕耦合分配。 这些块通过两个大致平行的绝缘电线互连，通过一个冲压的导电金属板夹紧在适当的位置，该导电金属板具有咬合在块互连线上并穿过绝缘体的成形角，每个塑料顶部和底部各自 块被压制并声波焊接在一起。 冲压的导电金属板形成有位于块中的向下纵向延伸的脊，使得底部边缘抵靠并沿着其上安装有每个块的线的绝缘体。
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10.发明授权Removal of heparin from heparin-containing blood plasma samples using a triethylaminoethyl cellulose tablet 失效使用三乙基氨基乙基纤维素片从含肝素的血浆样品中除去肝素
公开(公告)号：US4226599A
公开(公告)日：1980-10-07
申请号：US050355
申请日：1979-06-20
CPC分类号： G01N33/86 , G01N2400/40 , Y10T436/25125
摘要： A tableted form of fibrous triethylaminoethyl cellulose suitable for the removal of heparin from heparin-containing blood plasma. The tablet is composed of granular microcrystalline cellulose and fibrous triethylaminoethyl cellulose in a ratio of from about 5.4:1 to about 10:1. The triethylaminoethyl cellulose tablet, which is formulated to provide from about 5 to about 26 mg. of triethylaminoethyl cellulose per milliliter of plasma sample, is added to a heparin-containing blood plasma sample, the sample is agitated or allowed to stand for a time sufficient to permit adsorption of substantially all heparin present. The sample is then centrifuged and the remaining heparin-free plasma can be subjected to coagulation testing in order to determine the true clotting time.
摘要翻译： 纤维状三乙基氨基乙基纤维素的片状形式，适用于从含有肝素的血浆中除去肝素。 片剂由粒状微晶纤维素和纤维状三乙基氨基乙基纤维素组成，比例约为5.4:1至约10:1。 三乙氨基乙基纤维素片剂，其配制成提供约5至约26mg。 的三乙胺基乙基纤维素/毫升血浆样品加入含肝素的血浆样品中，将样品搅拌或静置足以允许存在基本上所有肝素的吸附。 然后将样品离心，然后将剩余的无肝素血浆进行凝血试验，以确定真实的凝血时间。
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