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公开(公告)号：US5900726A
公开(公告)日：1999-05-04
申请号：US876445
申请日：1997-06-16
CPC分类号： A61M1/16 , A61M1/361 , A61M1/3612 , A61M1/3653 , A61M1/3658 , A61M1/3669 , G01F1/7046 , G01F1/708 , G01F1/7088
摘要： A flow rate of a fluid flowing in a tube is quantitatively determined by altering the electrical conductivity of the fluid by injection of a bolus of saline. The electrical conductivity of the altered conductivity is measured over the time it takes the altered conductivity fluid to pass a conductivity measuring location. The measured conductivity is integrated over the time it takes to pass the conductivity measuring location. The integral is interpreted to determine the flow rate.
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公开(公告)号：US5570026A
公开(公告)日：1996-10-29
申请号：US455349
申请日：1995-05-31
IPC分类号： G01N27/06 , A61M1/14 , A61M1/16 , A61M1/36 , G01F1/704 , G01F1/708 , G01N27/02 , G01N33/487 , G01R27/02 , G01N27/08
CPC分类号： G01F1/7088 , A61M1/16 , A61M1/361 , A61M1/3612 , A61M1/3653 , A61M1/3658 , A61M1/3669 , G01F1/7046 , G01F1/708
摘要： A differential conductivity recirculation monitor quantitatively determines the degree of recirculation in a fistula by comparing the conductivity of blood entering the fistula to the conductivity of blood being withdrawn from the fistula. A discrete quantity of a high conductivity marker fluid is injected into the blood entering the fistula, altering the conductivity of the blood entering the fistula. The altered conductivity blood enters the fistula and, if recirculation is present, co-mingles with blood in the fistula, altering the conductivity of the blood in the fistula in proportion to the degree of recirculation. Blood withdrawn from the fistula has an altered conductivity related to the degree of recirculation. Quantitative values of the conductivity of the altered conductivity blood entering the fistula and the conductivity of the blood being withdrawn from the fistula are measured and a difference determined. The determined difference between the conductivities is used to determine a quantitative measurement of the degree of recirculation in the fistula.
摘要翻译： 差分电导率再循环监测器通过比较进入瘘的血液的电导率与从瘘管抽取的血液的电导率来定量地确定瘘管中的再循环程度。 将离散量的高电导率标记液注入进入瘘管的血液中，改变进入瘘管的血液的电导率。 改变的电导率血液进入瘘管，如果存在再循环，则与瘘管中的血液共混，根据再循环程度改变瘘管中的血液的电导率。 从瘘管中取出的血液与再循环程度相关的导电性改变。 测量进入瘘的改变的导电性血液的导电性的定量值和从瘘管取出的血液的电导率，并确定差异。 电导率之间的确定差异用于确定瘘管再循环程度的定量测量。
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公开(公告)号：US5510717A
公开(公告)日：1996-04-23
申请号：US454685
申请日：1995-05-31
IPC分类号： G01N27/06 , A61M1/14 , A61M1/16 , A61M1/36 , G01F1/704 , G01F1/708 , G01N27/02 , G01N33/487 , G01R27/02 , B01D61/32
CPC分类号： G01F1/7088 , A61M1/16 , A61M1/361 , A61M1/3612 , A61M1/3653 , A61M1/3658 , A61M1/3669 , G01F1/7046 , G01F1/708
摘要： A differential conductivity recirculation monitor quantitatively determines the degree of recirculation in a fistula by comparing the conductivity of blood entering the fistula to the conductivity of blood being withdrawn from the fistula. A discrete quantity of a high conductivity marker fluid is injected into the blood entering the fistula, altering the conductivity of the blood entering the fistula. The altered conductivity blood enters the fistula and, if recirculation is present, co-mingles with blood in the fistula, altering the conductivity of the blood ion the fistula in proportion to the degree of recirculation. Blood withdrawn from the fistula has an altered conductivity related to the degree of recirculation. Quantitative values of the conductivity of the altered conductivity blood entering the fistula and the conductivity of the blood being withdrawn from the fistula are measured and a difference determined. The determined difference between the conductivities is used to determine a quantitative measurement of the degree of recirculation in the fistula.
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公开(公告)号：US06912917B2
公开(公告)日：2005-07-05
申请号：US10630004
申请日：2003-07-29
CPC分类号： A61M1/16 , A61M1/361 , A61M1/3612 , A61M1/3653 , A61M1/3655 , A61M1/3658 , A61M1/3659 , A61M1/3661 , A61M1/3669 , G01F1/7046 , G01F1/708 , G01F1/7088
摘要： Methods and apparatuses for determining a fluid parameter in a vessel by altering a property of the fluid, sensing the difference in the property after the fluid is altered, particularly as related to the property in an unaltered portion of the fluid.
摘要翻译： 用于通过改变流体的性质来确定容器中的流体参数的方法和装置，感测流体改变后特性的差异，特别是与流体的未改变部分中的性质有关。
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公开(公告)号：US06614212B2
公开(公告)日：2003-09-02
申请号：US10238164
申请日：2002-09-10
IPC分类号： G01N2700
CPC分类号： A61M1/16 , A61M1/361 , A61M1/3612 , A61M1/3653 , A61M1/3655 , A61M1/3658 , A61M1/3659 , A61M1/3661 , A61M1/3669 , G01F1/7046 , G01F1/708 , G01F1/7088
摘要： Method and apparatus for quantitatively determining a degree of recirculalion flow in a vessel of a fluid by altering the electrical conductivity of the fluid, sensing the difference in electromagnetic field after the fluid is altered, and integrating the sensed difference over a period of time including any time of potential recirculation of any altered conductivity fluid.
摘要翻译： 用于通过改变流体的电导率来定量地确定流体容器中的再循环流程的程度和装置，检测流体改变后电磁场的差异，以及在一段时间内积分感测的差异，包括任何 任何改变的导电液体的潜在再循环的时间。
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公开(公告)号：US5510716A
公开(公告)日：1996-04-23
申请号：US332647
申请日：1994-11-01
IPC分类号： G01N27/06 , A61M1/14 , A61M1/16 , A61M1/36 , G01F1/704 , G01F1/708 , G01N27/02 , G01N33/487 , G01R27/02 , B01D61/32
CPC分类号： G01F1/7088 , A61M1/16 , A61M1/361 , A61M1/3612 , A61M1/3653 , A61M1/3658 , A61M1/3669 , G01F1/7046 , G01F1/708
摘要： A differential conductivity recirculation monitor quantitatively determines the degree of recirculation in a fistula by comparing the conductivity of blood entering the fistula to the conductivity of blood being withdrawn from the fistula. A discrete quantity of a high conductivity marker fluid is injected into the blood entering the fistula, altering the conductivity of the blood entering the fistula. The altered conductivity blood enters the fistula and, if recirculation is present, co-mingles with blood in the fistula, altering the conductivity of the blood ion the fistula in proportion to the degree of recirculation. Blood withdrawn from the fistula has an altered conductivity related to the degree of recirculation. Quantitative values of the conductivity of the altered conductivity blood entering the fistula and the conductivity of the blood being withdrawn from the fistula are measured and a difference determined. The determined difference between the conductivities is used to determine a quantitative measurement of the degree of recirculation in the fistula.
摘要翻译： 差分电导率再循环监测器通过比较进入瘘的血液的电导率与从瘘管抽取的血液的电导率来定量地确定瘘管中的再循环程度。 将离散量的高电导率标记液注入进入瘘管的血液中，改变进入瘘管的血液的电导率。 改变的电导率血液进入瘘管，并且如果存在再循环，则与瘘管中的血液共混，改变与再循环程度成比例的血液离子瘘的电导率。 从瘘管中取出的血液与再循环程度相关的导电性改变。 测量进入瘘的改变的导电性血液的导电性的定量值和从瘘管取出的血液的电导率，并确定差异。 电导率之间的确定差异用于确定瘘管再循环程度的定量测量。
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公开(公告)号：US5631552A
公开(公告)日：1997-05-20
申请号：US472268
申请日：1995-06-07
申请人： Francis T. Ogawa , James M. Brugger
发明人： Francis T. Ogawa , James M. Brugger
CPC分类号： G01F1/7088 , A61M1/16 , A61M1/361 , A61M1/3612 , A61M1/3653 , A61M1/3658 , A61M1/3669 , G01F1/7046 , G01F1/708
摘要： The presence of air bubbles entrained in a liquid flowing through a tube is detected flowing the liquid through a conduit which comprises a conductivity cell with a continuous path configuration. An electrical current is induced in the liquid in the conductivity cell. The electrical current in the liquid in the conductivity cell is sensed and interpreted, a decrease in the electrical current being indicative of the presence of an air bubble in the liquid. The conductivity cell comprises an upstream connection, a downstream connection, and two branches connecting the upstream connection to the downstream connection with a continuous path configuration from the upstream connection to the downstream connection through one of the two branches and returning to the upstream connection through the other one of the two branches.
摘要翻译： 检测到夹带在流过管的液体中的气泡的存在使液体流过包括具有连续路径构造的电导池的导管。 在电导池中的液体中产生电流。 感测和解释导电池中的液体中的电流，电流的减小表示液体中存在气泡。 电导率单元包括上游连接，下游连接以及将上游连接与下游连接相连接的两个分支，其具有从上游连接到通过两个分支之一的下游连接的连续路径配置，并返回到上游连接 另外两个分支之一。
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公开(公告)号：US09551625B2
公开(公告)日：2017-01-24
申请号：US14115924
申请日：2012-05-31
申请人： James M. Brugger , Dennis M. Treu , Jeffrey H. Burbank , Scott W. Newell , William J. Schnell , Kenneth E. Buckler
发明人： James M. Brugger , Dennis M. Treu , Jeffrey H. Burbank , Scott W. Newell , William J. Schnell , Kenneth E. Buckler
CPC分类号： G01L9/006 , A61M1/3639 , A61M1/3641 , A61M1/3653 , A61M1/3659 , A61M2205/3331 , A61M2205/75 , A61M2207/00 , G01L9/0041 , G01L19/0023 , G01L19/003 , G01L19/0046
摘要： A pressure measurement system for use in blood circuits comprised of a pressure sensing pod and a force measurement device. The pressure sensing pod can include a flexible, moveable, fluid-impermeable diaphragm and can be formed via either a one-shot or a two-shot molding process. A mechanical engagement member of the force measurement device engages with a mechanical engagement feature of the diaphragm, and the engagement member is operative to move in concert with movement of the engagement feature of the diaphragm based on pressure variations with the pressure sensing pod. The force measurement device generates and outputs to a processor a signal based on detected force associated with movement of the engagement member.
摘要翻译： 一种用于血液回路的压力测量系统，包括压力感测盒和力测量装置。 压力传感荚可以包括柔性的，可移动的，不透液体的隔膜，并且可以通过单次或两次成型工艺形成。 力测量装置的机械接合构件与隔膜的机械接合特征接合，并且接合构件可操作以基于与压力感测盒的压力变化相关联的隔膜的接合特征的移动。 力测量装置基于与接合构件的运动相关联的检测力产生并输出到处理器的信号。
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公开(公告)号：US07901579B2
公开(公告)日：2011-03-08
申请号：US12432507
申请日：2009-04-29
申请人： James M. Brugger , Martin Stillig
发明人： James M. Brugger , Martin Stillig
CPC分类号： A61M1/3627 , B01D19/0021 , B01D19/0042 , B01D61/20 , B01D61/30 , B01D63/00 , B01D63/02 , B01D65/00 , B01D2313/06 , B01D2313/18
摘要： A configuration of a blood microtubular filter/dialyzer used in many kinds of renal replacement therapy systems can provide a highly effective mechanism for removing air from the blood circuit of such systems. Air is removed from an outlet header space of the filter avoiding the need for a bubble trap or settling chamber such as a drip chamber.
摘要翻译： 用于多种肾替代治疗系统的血液微管过滤器/透析器的结构可以提供从这种系统的血液回路中去除空气的高效机制。 空气从过滤器的出口集管空间移除，避免了气泡陷阱或沉降室如滴水室的需要。
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公开(公告)号：US20100228231A1
公开(公告)日：2010-09-09
申请号：US12782557
申请日：2010-05-18
申请人： William Weigel , Kenneth Everett Buckler , Jeffrey H. Burbank , James M. Brugger , David Farias De Souza
发明人： William Weigel , Kenneth Everett Buckler , Jeffrey H. Burbank , James M. Brugger , David Farias De Souza
IPC分类号： A61M39/10
CPC分类号： A61M39/1011 , A61M2039/1016 , A61M2039/1033 , Y10S604/905
摘要： The present application describes devices that use various features to prevent the disconnection of connectors used in medical treatments. For example embodiments prevent disconnection of luer connectors that are incompletely mated.
摘要翻译： 本申请描述了使用各种特征来防止在医疗中使用的连接器断开的装置。 例如，实施例防止未完全配合的鲁尔连接器的断开。
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