公开(公告)号：US20060078086A1

公开(公告)日：2006-04-13

申请号：US11189431

申请日：2005-07-25

申请人： James Riley ,  Eric Meier ,  J. Wright ,  Steven Dimmer ,  Timothy Mate

发明人： James Riley ,  Eric Meier ,  J. Wright ,  Steven Dimmer ,  Timothy Mate

IPC分类号： A61N5/10

CPC分类号： A61N5/1038 ,  A61N5/103 ,  A61N5/1048

摘要： A facility for facilitating custom radiation treatment planning is described. During a distinguished radiation treatment session for a patient, the facility collects data indicating positioning of a predefined treatment site of the patient relative to a target treatment location throughout the distinguished radiation treatment session. The facility associates the collected positioning data with data describing one or more other aspects of the distinguished radiation treatment session. The facility provides the associated data to a treatment planning facility to determine a treatment plan for future radiation treatment sessions for the patient.

公开(公告)号：US20060074301A1

公开(公告)日：2006-04-06

申请号：US11190193

申请日：2005-07-25

申请人： Eric Meier ,  Timothy Mate ,  J. Wright ,  Steven Dimmer ,  Lynn Purdy

发明人： Eric Meier ,  Timothy Mate ,  J. Wright ,  Steven Dimmer ,  Lynn Purdy

IPC分类号： A61B5/05

CPC分类号： A61N5/1039 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1051

摘要： An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy type to identify the marker that is different than the first energy type.

公开(公告)号：US20060093089A1

公开(公告)日：2006-05-04

申请号：US11165843

申请日：2005-06-24

申请人： Edward Vertatschitsch ,  Steven Dimmer ,  Timothy Mate ,  Eric Meier ,  Keith Seiler ,  J. Wright

发明人： Edward Vertatschitsch ,  Steven Dimmer ,  Timothy Mate ,  Eric Meier ,  Keith Seiler ,  J. Wright

IPC分类号： A61N5/10

CPC分类号： A61N5/1049 ,  A61B34/25 ,  A61B34/30 ,  A61B2034/301 ,  A61B2090/3958 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1051

摘要： Systems and methods for treating a lung of a patient. One embodiment of a method comprises positioning a leadless marker in the lung of the patient relative to the target, and collecting position data of the marker. This method further comprises determining the location of the marker in an external reference frame outside of the patient based on the collected position data, and providing an objective output in the external reference frame that is responsive to movement of the marker. The objective output is provided at a frequency (i.e., periodicity) that results in a clinically acceptable tracking error. In addition, the objective output can also be provided at least substantially contemporaneously with collecting the position data used to determine the location of the marker.

摘要翻译： 用于治疗患者肺部的系统和方法。 一种方法的一个实施例包括将无引线标记物相对于靶标定位在患者的肺中，以及收集标记物的位置数据。 该方法还包括基于所收集的位置数据确定标记在患者外部的外部参考框架中的位置，以及响应于标记的移动而在外部参考框架中提供客观输出。 以导致临床上可接受的跟踪误差的频率（即，周期性）提供目标输出。 此外，目标输出还可以至少基本同时提供，收集用于确定标记位置的位置数据。

公开(公告)号：US20060058648A1

公开(公告)日：2006-03-16

申请号：US11190195

申请日：2005-07-25

申请人： Eric Meier ,  Timothy Mate ,  J. Wright ,  Steven Dimmer ,  Lynn Purdy

发明人： Eric Meier ,  Timothy Mate ,  J. Wright ,  Steven Dimmer ,  Lynn Purdy

IPC分类号： A61B6/00

CPC分类号： A61N5/1039 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1051

摘要： An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy type to identify the marker that is different than the first energy type.

公开(公告)号：US20060074302A1

公开(公告)日：2006-04-06

申请号：US11190196

申请日：2005-07-25

申请人： Eric Meier ,  Timothy Mate ,  J. Wright ,  Steven Dimmer ,  Lynn Purdy

发明人： Eric Meier ,  Timothy Mate ,  J. Wright ,  Steven Dimmer ,  Lynn Purdy

IPC分类号： A61B5/05

CPC分类号： A61N5/1039 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1051

摘要： An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy type to identify the marker that is different than the first energy type.

摘要翻译： 综合放射治疗过程包括通过使用定位模式周期性地定位位于患者内的标记来获取与患者内的目标参数有关的第一目标目标数据。 该方法继续通过周期性地定位标记来获得与目标参数相关的第二目标目标数据。 第一目标数据可以在离开包含用于产生用于治疗患者的电离辐射束的辐射递送装置的第二区域的第一区域中获取。 第一和第二区域的定位方式可以相同。 在其他实施例中，可以使用使用第一能量类型来识别标记的第一定位模态来获取第一目标目标数据，并且可以使用第二定位模式来获得第二目标数据，第二定位模式使用第二能量类型来识别 不同于第一种能量类型的标记。

公开(公告)号：US20050261570A1

公开(公告)日：2005-11-24

申请号：US10722015

申请日：2003-11-25

申请人： Timothy Mate ,  Steven Dimmer

发明人： Timothy Mate ,  Steven Dimmer

IPC分类号： G01V3/00 ,  A61B5/07 ,  A61B19/00 ,  A61N5/10 ,  G01S5/06 ,  G01V15/00 ,  A61B5/05

CPC分类号： A61N5/1049 ,  A61B34/20 ,  A61B2034/2051 ,  A61B2034/2072 ,  A61B2090/3958 ,  A61N5/107 ,  A61N2005/105 ,  A61N2005/1051

摘要： A system and method for accurately locating and tracking the position of a target, such as a tumor or the like, within a body. In one embodiment, the system is a target locating and monitoring system usable with a radiation delivery source that delivers selected doses of radiation to a target in a body. The system includes one or more excitable markers positionable in or near the target, an external excitation source that remotely excites the markers to produce an identifiable signal, and a plurality of sensors spaced apart in a known geometry relative to each other. A computer is coupled to the sensors and configured to use the marker measurements to identify a target isocenter within the target. The computer compares the position of the target isocenter with the location of the machine isocenter. The computer also controls movement of the patient and a patient support device so the target isocenter is coincident with the machine isocenter before and during radiation therapy.

摘要翻译： 一种用于在身体内准确定位和跟踪诸如肿瘤等的靶的位置的系统和方法。 在一个实施例中，该系统是可与辐射递送源一起使用的目标定位和监测系统，其将选定剂量的辐射递送到身体中的目标。 该系统包括可定位在靶内或附近的一个或多个可激发标记，远程激发标记以产生可识别信号的外部激发源以及以已知几何形状相对于彼此间隔开的多个传感器。 计算机耦合到传感器并且被配置为使用标记测量来识别目标内的目标等角点。 计算机将目标等角点的位置与机器等角点的位置进行比较。 计算机还控制患者和患者支撑装置的运动，使得目标等角点在辐射治疗之前和放射治疗期间与机器等角点重合。

公开(公告)号：US20080001756A1

公开(公告)日：2008-01-03

申请号：US11627693

申请日：2007-01-26

申请人： Steven Dimmer ,  J. Wright ,  William Mayo

发明人： Steven Dimmer ,  J. Wright ,  William Mayo

IPC分类号： G08B13/14

CPC分类号： G08B13/2414 ,  A61B5/06 ,  A61B5/062 ,  A61B34/20 ,  A61B90/36 ,  A61B2017/00154 ,  A61B2017/00411 ,  A61B2034/2051 ,  A61B2090/3958 ,  A61B2090/3975 ,  A61N5/1049 ,  A61N2005/1051 ,  H01Q7/08

摘要： A system for generating a magnetic field for excitation of a leadless marker assembly. The system of at least one embodiment includes a source generator that generates a plurality of alternating electrical signals each having an independently adjustable phase. A plurality of excitation coils are configured to simultaneously receive a respective one of the alternating electrical signals at a selected phase to generate a magnetic field. The phase of the alternating electrical signal for each excitation coil is independently adjustable relative to the phase of the alternating electrical signal for the other excitation coils so as to adjust the magnetic field from the respective coil. The magnetic fields from the excitation coils combine to form a spatially adjustable excitation field for excitation of the remote leadless marker assembly.

摘要翻译： 一种用于产生用于无引线标记组件的激励的磁场的系统。 至少一个实施例的系统包括源发生器，其产生多个具有独立可调相位的交替电信号。 多个激励线圈被配置为在选定的相位处同时接收相应的一个交流电信号以产生磁场。 每个励磁线圈的交流电信号的相位相对于其他励磁线圈的交变电信号的相位可独立地调节，以便调整来自相应线圈的磁场。 来自激励线圈的磁场组合形成用于激发远程无引线标记组件的空间可调的激励场。

公开(公告)号：US20050195084A1

公开(公告)日：2005-09-08

申请号：US10997080

申请日：2004-11-23

申请人： Steven Dimmer ,  J. Wright ,  William Mayo

发明人： Steven Dimmer ,  J. Wright ,  William Mayo

IPC分类号： G01B7/00 ,  A61B19/00 ,  A61N5/10 ,  G01S5/16 ,  G08B13/24 ,  G08B13/14

CPC分类号： G08B13/2414 ,  A61B5/06 ,  A61B5/062 ,  A61B34/20 ,  A61B90/36 ,  A61B2017/00154 ,  A61B2017/00411 ,  A61B2034/2051 ,  A61B2090/3958 ,  A61B2090/3975 ,  A61N5/1049 ,  A61N2005/1051 ,  H01Q7/08

摘要： A system for generating a magnetic field for excitation of a leadless marker assembly. The system of at least one embodiment includes a source generator that generates a plurality of alternating electrical signals each having an independently adjustable phase. A plurality of excitation coils are configured to simultaneously receive a respective one of the alternating electrical signals at a selected phase to generate a magnetic field. The phase of the alternating electrical signal for each excitation coil is independently adjustable relative to the phase of the alternating electrical signal for the other excitation coils so as to adjust the magnetic field from the respective coil. The magnetic fields from the excitation coils combine to form a spatially adjustable excitation field for excitation of the remote leadless marker assembly.

摘要翻译： 一种用于产生用于无引线标记组件的激励的磁场的系统。 至少一个实施例的系统包括源发生器，其产生多个具有独立可调相位的交替电信号。 多个激励线圈被配置为在选定的相位处同时接收相应的一个交流电信号以产生磁场。 每个励磁线圈的交流电信号的相位相对于其他励磁线圈的交变电信号的相位可独立地调节，以便调整来自相应线圈的磁场。 来自激励线圈的磁场组合形成用于激发远程无引线标记组件的空间可调的激励场。

公开(公告)号：US20060100509A1

公开(公告)日：2006-05-11

申请号：US11190205

申请日：2005-07-25

申请人： J. Wright ,  Steven Dimmer ,  Stephen Phillips ,  Ryan Seghers

发明人： J. Wright ,  Steven Dimmer ,  Stephen Phillips ,  Ryan Seghers

IPC分类号： A61B5/05

CPC分类号： A61N5/1049 ,  A61B2090/3958 ,  A61N5/107 ,  A61N2005/1051

摘要： A facility for processing data is described. The facility receives a stream of digital location indications, each location indication identifying a location of a patient while undergoing radiation therapy. In response to each location indication of the string, in substantially real-time relative to the receipt of the position indication, the facility performs an action responsive to the location indication.

摘要翻译： 描述处理数据的设施。 该设施接收数字位置指示流，每个位置指示在进行放射治疗时识别患者的位置。 响应于字符串的每个位置指示，基本上实时地相对于接收到位置指示，设施执行响应于位置指示的动作。

公开(公告)号：US20060079764A1

公开(公告)日：2006-04-13

申请号：US11166801

申请日：2005-06-24

申请人： J. Wright ,  Steven Dimmer

发明人： J. Wright ,  Steven Dimmer

IPC分类号： A61B6/00

CPC分类号： A61B5/06 ,  A61B5/055 ,  A61B6/12 ,  A61B8/0833 ,  A61B34/20 ,  A61B34/25 ,  A61B90/36 ,  A61B90/39 ,  A61B2034/2051 ,  A61B2034/252 ,  A61B2090/3908 ,  A61B2090/3954 ,  A61B2090/3958 ,  A61B2090/3995 ,  A61N5/1049 ,  A61N5/1067 ,  A61N5/107 ,  A61N2005/1051

摘要： Systems and methods for tracking targets in real time for radiation therapy and other applications. In one embodiment, a method includes collecting position information of a marker implanted within a patient at a site relative to the target at a time tn, and providing an objective output indicative of the location of the target based on the position information collected at time tn. The objective output is provided to a memory device, user interface, and/or radiation delivery machine within 1 ms to 2 seconds of the time tn when the position information was collected. This embodiment of the method can further include providing the objective output at a periodicity of 10-200 ms during at least a portion of a treatment procedure. For example, the method can further include generating a beam of ionizing radiation and directing the beam to a machine isocenter, and continuously repeating the collecting procedure and the providing procedure every 10-200 ms while irradiating the patient with the ionizing radiation beam.

摘要翻译： 用于实时跟踪靶向放射治疗和其他应用的系统和方法。 在一个实施例中，一种方法包括在时间t n n处收集在相对于目标的位置处植入在患者内的标记的位置信息，并且提供指示基于目标的位置的客观输出 关于在时间t 收集的位置信息。 当收集位置信息时，目标输出被提供给存储器装置，用户界面和/或辐射递送机器，在时间t n n n 1的1秒至2秒内。 该方法的该实施例还可以包括在至少一部分治疗过程期间以10-200ms的周期提供目标输出。 例如，该方法可以进一步包括产生电离辐射束并将光束引导到机器等角点，并且在每隔10-200毫秒同时持续地重复采集过程和提供过程，同时用电离辐射束照射患者。