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公开(公告)号：US20120136243A1
公开(公告)日：2012-05-31
申请号：US13302170
申请日：2011-11-22
IPC分类号： A61B5/05
CPC分类号： A61B6/481 , A61B5/0275 , A61B6/4458 , A61B6/4464 , A61B6/50 , A61B6/501 , A61B6/504 , A61B6/507
摘要： A method for calculating perfusion data, such as blood volume or blood flow from 2-D angiography data or DSA sequences, is proposed. An angiography scene is recorded using specific acquisition parameters to generate the 2-D angiography data or DSA sequences with administration of contrast agent based on a multiplicity of individual angiography images. A region of interest is defined suitable for comparison purposes. The volume segments are defined by the region of interest. The time/contrast curve is determined in the volume segments. Perfusion data for calculating the relative perfusion data is ascertained. The perfusion data is compared and the relative perfusion data is calculated. The calculated relative perfusion data is not specified in terms of absolute physical quantities, but is provided simply as ratios, such as left/right or before/after.
摘要翻译： 提出了一种从二维血管造影数据或DSA序列计算灌注数据如血容量或血流量的方法。 使用特定采集参数记录血管造影场景，以基于多个单独的血管造影图像施用造影剂来产生2-D血管造影数据或DSA序列。 感兴趣的区域被定义为适合于比较目的。 音量段由感兴趣的区域定义。 时间/对比度曲线在音量段中确定。 确定用于计算相对灌注数据的灌注数据。 比较灌注数据，计算相对灌注数据。 计算的相对灌注数据不是以绝对物理量表示，而是简单地作为比例提供，例如左/右或之前/之后。
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公开(公告)号：US20110075798A1
公开(公告)日：2011-03-31
申请号：US12891849
申请日：2010-09-28
申请人： Jan Boese , Klaus Klingenbeck
发明人： Jan Boese , Klaus Klingenbeck
CPC分类号： A61B6/5241 , A61B6/032 , A61B6/4441 , A61B6/4458 , G06T11/005 , G06T2211/432
摘要： A method for correcting truncated projection data of a rotation for a reconstruction technique for computed tomography scans with truncated projection data in the computed tomography images produced by a C-arm is proposed. At least one truncated projection is recorded. The truncated portions prior to acquisition of the rotation for the at least one truncated projection is captured. The truncated projection and the truncated portions are assembled into at least one complete projection. Truncated projection data is acquired during the rotation. The truncated data is estimated based on a model of the patient geometry from the at least one complete projection. A reconstruction technique is performed on the basis of the acquired and the estimated data.
摘要翻译： 提出了一种通过C臂产生的计算机断层图像中的截断的投影数据来校正用于计算机断层摄影扫描的重建技术的旋转的截断投影数据的方法。 至少记录一个截断的投影。 捕获用于至少一个截断投影的旋转获取之前的截断部分。 截头突起和截头部分组装成至少一个完整的突起。 截断的投影数据在旋转期间获取。 基于来自至少一个完整投影的患者几何形状的模型来估计截断的数据。 基于获取的和估计的数据执行重建技术。
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3.发明授权Method and system for intraoperative guidance using physiological image fusion 有权使用生理图像融合进行术中指导的方法和系统公开(公告)号：US08532352B2
公开(公告)日：2013-09-10
申请号：US13267662
申请日：2011-10-06
申请人： Razvan Ioan Ionasec , Ingmar Voigt , Bogdan Georgescu , Yefeng Zheng , Jan Boese , Klaus Klingenbeck , Dorin Comaniciu
发明人： Razvan Ioan Ionasec , Ingmar Voigt , Bogdan Georgescu , Yefeng Zheng , Jan Boese , Klaus Klingenbeck , Dorin Comaniciu
IPC分类号： G06K9/00
CPC分类号： G06T19/006 , G06T7/344 , G06T17/00 , G06T2207/10072 , G06T2207/10121 , G06T2207/10136 , G06T2207/30048 , G16H50/50
摘要： A method and system for intraoperative guidance in an off-pump mitral valve repair procedure is disclosed. A plurality of patient-specific models of the mitral valve are generated, each from pre-operative image data obtained using a separate imaging modality. The pre-operative image data from the separate imaging modalities are fused into a common coordinate system by registering the plurality of patient-specific models. A model of the mitral valve is estimated in real-time in intraoperative image data using a fused physiological prior resulting from the registering of the plurality of patient-specific models.
摘要翻译： 公开了一种用于非抽血二尖瓣修复手术中术中引导的方法和系统。 产生多个患者特异性二尖瓣模型，每个来自使用单独成像模态获得的术前图像数据。 来自分开的成像模态的手术前图像数据通过登记多个患者特定模型而融合到公共坐标系中。 使用由多个患者特定模型的登记产生的融合生理学先验在实际的术中图像数据中估计二尖瓣的模型。
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4.发明申请Method and System for Intraoperative Guidance Using Physiological Image Fusion 有权使用生理图像融合进行术中指导的方法和系统公开(公告)号：US20120087563A1
公开(公告)日：2012-04-12
申请号：US13267662
申请日：2011-10-06
申请人： Razvan Ioan Ionasec , Ingmar Voigt , Bogdan Georgescu , Yefeng Zheng , Jan Boese , Klaus Klingenbeck , Dorin Comaniciu
发明人： Razvan Ioan Ionasec , Ingmar Voigt , Bogdan Georgescu , Yefeng Zheng , Jan Boese , Klaus Klingenbeck , Dorin Comaniciu
IPC分类号： G06K9/00
CPC分类号： G06T19/006 , G06T7/344 , G06T17/00 , G06T2207/10072 , G06T2207/10121 , G06T2207/10136 , G06T2207/30048 , G16H50/50
摘要： A method and system for intraoperative guidance in an off-pump mitral valve repair procedure is disclosed. A plurality of patient-specific models of the mitral valve are generated, each from pre-operative image data obtained using a separate imaging modality. The pre-operative image data from the separate imaging modalities are fused into a common coordinate system by registering the plurality of patient-specific models. A model of the mitral valve is estimated in real-time in intraoperative image data using a fused physiological prior resulting from the registering of the plurality of patient-specific models.
摘要翻译： 公开了一种用于非抽血二尖瓣修复手术中术中引导的方法和系统。 产生多个患者特异性二尖瓣模型，每个来自使用单独成像模态获得的术前图像数据。 来自分开的成像模态的手术前图像数据通过登记多个患者特定模型而融合到公共坐标系中。 使用由多个患者特定模型的登记产生的融合生理学先验在实际的术中图像数据中估计二尖瓣的模型。
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5.发明申请Registering intra-operative image data sets with pre-operative 3D image data sets on the basis of optical surface extraction 有权基于光学表面提取，将手术前图像数据集与术前3D图像数据集进行注册公开(公告)号：US20070238952A1
公开(公告)日：2007-10-11
申请号：US11496069
申请日：2006-07-28
IPC分类号： A61B5/05
CPC分类号： G06T7/55 , G06T7/38 , G06T7/50 , G06T2207/30004
摘要： The invention relates to a method for registering intra-operative image data set with pre-operative 3D image data set, comprising: spatial calibrating an optical 3D sensor system with an intra-operative imaging modality, intra-operative detecting the surface of an examination area of interest with the 3D sensor system to produce an intra-operative surface mask, intra-operative recording the area of interest for examination with the intra-operative modality at least partly containing the intra-operative surface mask to obtain an intra-operative image data set, computing the same surface from the pre-operative 3D image data set containing the detected surface to obtain a pre-operative surface mask, registering the intra-operative and pre-operative surface mask with each other, determining a mapping specification between pre-operative 3D image data set and intra-operative image data set based on the calibration and the registration, and overlaying the intra-operative image data set with the pre-operative 3D data set based on the mapping specification.
摘要翻译： 本发明涉及一种用于记录术前图像数据组与手术前3D图像数据集的方法，包括：用术中成像模态对光学3D传感器系统进行空间校准，手术中检测检查区域的表面 感兴趣的3D传感器系统以产生术中表面掩模，用至少部分地包含术中表面掩模的手术内模式手术内记录用于检查的感兴趣区域以获得手术中图像数据 设置，从包含检测到的表面的术前3D图像数据集计算相同的表面，以获得术前表面掩模，将手术前和手术前表面掩模彼此对准， 基于校准和注册的手术3D图像数据集和手术中图像数据集，并且将术中图像数据集合与t 他基于映射规范进行手术前3D数据集。
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6.发明申请公开(公告)号：US20060058638A1
公开(公告)日：2006-03-16
申请号：US11222394
申请日：2005-09-08
IPC分类号： A61B5/05
CPC分类号： A61B6/504 , A61B5/055 , A61B6/032 , A61B6/507 , A61B6/541 , A61F2/07 , A61F2/90 , A61F2240/002
摘要： Method for the diagnosis and treatment of aortic aneurysms through representation of the affected area of the aorta by means of an imaging method and measurement of the image in order to produce a made-to-measure stent graft which is introduced into the aorta in the folded state and then expanded, a digital model of the aortic aneurysm being created from the images present as 3D volume data, from which digital model of the aortic aneurysm there is produced by means of iterative customizing software a digital model of the stent graft on the basis of which the stent graft is manufactured.
摘要翻译： 用于通过成像方法表示主动脉瘤的受影响区域并且对图像进行测量来诊断和治疗主动脉瘤的方法，以便产生将被测量的支架移植物引入到折叠的主动脉中 状态然后扩大，主动脉瘤的数字模型是从作为3D体积数据存在的图像创建的，其中主动脉瘤的数字模型通过迭代定制软件基于支架移植物的数字模型产生 其中制造了支架植入物。
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公开(公告)号：US08213565B2
公开(公告)日：2012-07-03
申请号：US12891849
申请日：2010-09-28
申请人： Jan Boese , Klaus Klingenbeck
发明人： Jan Boese , Klaus Klingenbeck
IPC分类号： A61B6/00
CPC分类号： A61B6/5241 , A61B6/032 , A61B6/4441 , A61B6/4458 , G06T11/005 , G06T2211/432
摘要： A method for correcting truncated projection data of a rotation for a reconstruction technique for computed tomography scans with truncated projection data in the computed tomography images produced by a C-arm is proposed. At least one truncated projection is recorded. The truncated portions prior to acquisition of the rotation for the at least one truncated projection is captured. The truncated projection and the truncated portions are assembled into at least one complete projection. Truncated projection data is acquired during the rotation. The truncated data is estimated based on a model of the patient geometry from the at least one complete projection. A reconstruction technique is performed on the basis of the acquired and the estimated data.
摘要翻译： 提出了一种通过C臂产生的计算机断层图像中的截断的投影数据来校正用于计算机断层摄影扫描的重建技术的旋转的截断投影数据的方法。 至少记录一个截断的投影。 捕获用于至少一个截断投影的旋转获取之前的截断部分。 截头突起和截头部分组装成至少一个完整的突起。 在旋转期间获取截断的投影数据。 基于来自至少一个完整投影的患者几何形状的模型来估计截断的数据。 基于获取的和估计的数据执行重建技术。
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8.发明授权Method for representing interventional instruments in a 3D data set of an anatomy to be examined as well as a reproduction system for performing the method 有权用于表示要检查的解剖结构的3D数据集中的介入仪器的方法以及用于执行该方法的再现系统公开(公告)号：US08068581B2
公开(公告)日：2011-11-29
申请号：US12507343
申请日：2009-07-22
申请人： Jan Boese , Klaus Klingenbeck
发明人： Jan Boese , Klaus Klingenbeck
IPC分类号： G01N23/04
CPC分类号： A61B5/06 , A61B5/745 , A61B6/12 , A61B6/4458 , A61B6/4464 , A61B6/466 , A61B6/5229 , A61B6/5241 , A61B34/20 , A61B90/37 , A61B2090/366 , A61B2090/367 , A61B2090/376 , G06F19/00
摘要： The invention relates to a method for presenting interventional instruments in a 3D data set of an anatomy to be treated. A 3D data set of the anatomy is recorded before introduction of an interventional instrument. Once the interventional instrument has been applied, the spatial position of the instrument is determined by x-ray fluoroscopy from images created at two different angulations. A 3D model of the instrument is formed from the x-ray images. The 3D model of the instrument is fused with the 3D data set of the anatomy. A 3D hologram is reproduced from the fused 3D data set. The 3D hologram is repeatedly reproduced in real time to follow the application of the instrument in the presentation.
摘要翻译： 本发明涉及一种用于在待治疗的解剖结构的3D数据集中呈现介入器械的方法。 在引入介入仪器之前记录解剖结构的3D数据集。 一旦介入仪器被应用，仪器的空间位置就是通过X射线荧光透视法确定的，这些图像是以两个不同角度产生的图像。 仪器的3D模型由X射线图像形成。 仪器的3D模型与解剖结构的3D数据集融合。 从融合的3D数据集再现3D全息图。 3D全息图在实时中反复再现，以便在演示中遵循仪器的应用。
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9.发明授权Registering intra-operative image data sets with pre-operative 3D image data sets on the basis of optical surface extraction 有权基于光学表面提取，将手术前图像数据集与术前3D图像数据集进行注册公开(公告)号：US07664542B2
公开(公告)日：2010-02-16
申请号：US11496069
申请日：2006-07-28
CPC分类号： G06T7/55 , G06T7/38 , G06T7/50 , G06T2207/30004
摘要： The invention relates to a method for registering intra-operative image data set with pre-operative 3D image data set, including: spatially calibrating an optical 3D sensor system with an intra-operative imaging modality, intra-operatively detecting the surface of an examination area of interest with the 3D sensor system to produce an intra-operative surface mask, intra-operatively recording the area of interest for examination with the intra-operative modality at least partly containing the intra-operative surface mask to obtain an intra-operative image data set, computing the same surface from the pre-operative 3D image data set containing the detected surface to obtain a pre-operative surface mask, registering the intra-operative and pre-operative surface mask with each other, determining a mapping specification between pre-operative 3D image data set and intra-operative image data set based on the calibration and the registration, and overlaying the intra-operative image data set with the pre-operative 3D data set based on the mapping specification.
摘要翻译： 本发明涉及一种用于记录术前图像数据组与手术前3D图像数据集的方法，所述方法包括：空间校准具有术中成像模态的光学3D传感器系统，操作内检测检查区域的表面 感兴趣的3D传感器系统以产生术中表面掩模，用至少部分地包含术中表面掩模的手术内模式操作内记录用于检查的感兴趣区域以获得手术中图像数据 设置，从包含检测到的表面的术前3D图像数据集计算相同的表面，以获得术前表面掩模，将手术前和手术前表面掩模彼此对准， 基于校准和注册的手术3D图像数据集和手术中图像数据集合，并且将术中图像数据集w 基于映射规范的术前3D数据集。
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公开(公告)号：US10719986B2
公开(公告)日：2020-07-21
申请号：US12975714
申请日：2010-12-22
申请人： Dominik Zaeuner , Razvan Ioan Ionasec , Bogdan Georgescu , Yefeng Zheng , Dorin Comaniciu , Ingmar Voigt , Jan Boese
发明人： Dominik Zaeuner , Razvan Ioan Ionasec , Bogdan Georgescu , Yefeng Zheng , Dorin Comaniciu , Ingmar Voigt , Jan Boese
摘要： A method and system for virtual percutaneous valve implantation is disclosed. A patient-specific anatomical model of a heart valve is estimated based on 3D cardiac medical image data and an implant model representing a valve implant is virtually deployed into the patient-specific anatomical model of the heart valve. A library of implant models, each modeling geometrical properties of a corresponding valve implant, is maintained. The implant models maintained in the library are virtually deployed into the patient specific anatomical model of the heart valve to select an implant type and size and deployment location and orientation for percutaneous valve implantation.
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