公开(公告)号：US20120136243A1

公开(公告)日：2012-05-31

申请号：US13302170

申请日：2011-11-22

申请人： Jan Boese ,  Andreas Fieselmann ,  Klaus Klingenbeck ,  Markus Kowarschik

发明人： Jan Boese ,  Andreas Fieselmann ,  Klaus Klingenbeck ,  Markus Kowarschik

IPC分类号： A61B5/05

CPC分类号： A61B6/481 ,  A61B5/0275 ,  A61B6/4458 ,  A61B6/4464 ,  A61B6/50 ,  A61B6/501 ,  A61B6/504 ,  A61B6/507

摘要： A method for calculating perfusion data, such as blood volume or blood flow from 2-D angiography data or DSA sequences, is proposed. An angiography scene is recorded using specific acquisition parameters to generate the 2-D angiography data or DSA sequences with administration of contrast agent based on a multiplicity of individual angiography images. A region of interest is defined suitable for comparison purposes. The volume segments are defined by the region of interest. The time/contrast curve is determined in the volume segments. Perfusion data for calculating the relative perfusion data is ascertained. The perfusion data is compared and the relative perfusion data is calculated. The calculated relative perfusion data is not specified in terms of absolute physical quantities, but is provided simply as ratios, such as left/right or before/after.

摘要翻译： 提出了一种从二维血管造影数据或DSA序列计算灌注数据如血容量或血流量的方法。 使用特定采集参数记录血管造影场景，以基于多个单独的血管造影图像施用造影剂来产生2-D血管造影数据或DSA序列。 感兴趣的区域被定义为适合于比较目的。 音量段由感兴趣的区域定义。 时间/对比度曲线在音量段中确定。 确定用于计算相对灌注数据的灌注数据。 比较灌注数据，计算相对灌注数据。 计算的相对灌注数据不是以绝对物理量表示，而是简单地作为比例提供，例如左/右或之前/之后。

公开(公告)号：US08213565B2

公开(公告)日：2012-07-03

申请号：US12891849

申请日：2010-09-28

申请人： Jan Boese ,  Klaus Klingenbeck

发明人： Jan Boese ,  Klaus Klingenbeck

IPC分类号： A61B6/00

CPC分类号： A61B6/5241 ,  A61B6/032 ,  A61B6/4441 ,  A61B6/4458 ,  G06T11/005 ,  G06T2211/432

摘要： A method for correcting truncated projection data of a rotation for a reconstruction technique for computed tomography scans with truncated projection data in the computed tomography images produced by a C-arm is proposed. At least one truncated projection is recorded. The truncated portions prior to acquisition of the rotation for the at least one truncated projection is captured. The truncated projection and the truncated portions are assembled into at least one complete projection. Truncated projection data is acquired during the rotation. The truncated data is estimated based on a model of the patient geometry from the at least one complete projection. A reconstruction technique is performed on the basis of the acquired and the estimated data.

摘要翻译： 提出了一种通过C臂产生的计算机断层图像中的截断的投影数据来校正用于计算机断层摄影扫描的重建技术的旋转的截断投影数据的方法。 至少记录一个截断的投影。 捕获用于至少一个截断投影的旋转获取之前的截断部分。 截头突起和截头部分组装成至少一个完整的突起。 在旋转期间获取截断的投影数据。 基于来自至少一个完整投影的患者几何形状的模型来估计截断的数据。 基于获取的和估计的数据执行重建技术。

公开(公告)号：US08068581B2

公开(公告)日：2011-11-29

申请号：US12507343

申请日：2009-07-22

申请人： Jan Boese ,  Klaus Klingenbeck

发明人： Jan Boese ,  Klaus Klingenbeck

IPC分类号： G01N23/04

CPC分类号： A61B5/06 ,  A61B5/745 ,  A61B6/12 ,  A61B6/4458 ,  A61B6/4464 ,  A61B6/466 ,  A61B6/5229 ,  A61B6/5241 ,  A61B34/20 ,  A61B90/37 ,  A61B2090/366 ,  A61B2090/367 ,  A61B2090/376 ,  G06F19/00

摘要： The invention relates to a method for presenting interventional instruments in a 3D data set of an anatomy to be treated. A 3D data set of the anatomy is recorded before introduction of an interventional instrument. Once the interventional instrument has been applied, the spatial position of the instrument is determined by x-ray fluoroscopy from images created at two different angulations. A 3D model of the instrument is formed from the x-ray images. The 3D model of the instrument is fused with the 3D data set of the anatomy. A 3D hologram is reproduced from the fused 3D data set. The 3D hologram is repeatedly reproduced in real time to follow the application of the instrument in the presentation.

摘要翻译： 本发明涉及一种用于在待治疗的解剖结构的3D数据集中呈现介入器械的方法。 在引入介入仪器之前记录解剖结构的3D数据集。 一旦介入仪器被应用，仪器的空间位置就是通过X射线荧光透视法确定的，这些图像是以两个不同角度产生的图像。 仪器的3D模型由X射线图像形成。 仪器的3D模型与解剖结构的3D数据集融合。 从融合的3D数据集再现3D全息图。 3D全息图在实时中反复再现，以便在演示中遵循仪器的应用。

公开(公告)号：US20120087563A1

公开(公告)日：2012-04-12

申请号：US13267662

申请日：2011-10-06

申请人： Razvan Ioan Ionasec ,  Ingmar Voigt ,  Bogdan Georgescu ,  Yefeng Zheng ,  Jan Boese ,  Klaus Klingenbeck ,  Dorin Comaniciu

发明人： Razvan Ioan Ionasec ,  Ingmar Voigt ,  Bogdan Georgescu ,  Yefeng Zheng ,  Jan Boese ,  Klaus Klingenbeck ,  Dorin Comaniciu

IPC分类号： G06K9/00

CPC分类号： G06T19/006 ,  G06T7/344 ,  G06T17/00 ,  G06T2207/10072 ,  G06T2207/10121 ,  G06T2207/10136 ,  G06T2207/30048 ,  G16H50/50

摘要： A method and system for intraoperative guidance in an off-pump mitral valve repair procedure is disclosed. A plurality of patient-specific models of the mitral valve are generated, each from pre-operative image data obtained using a separate imaging modality. The pre-operative image data from the separate imaging modalities are fused into a common coordinate system by registering the plurality of patient-specific models. A model of the mitral valve is estimated in real-time in intraoperative image data using a fused physiological prior resulting from the registering of the plurality of patient-specific models.

摘要翻译： 公开了一种用于非抽血二尖瓣修复手术中术中引导的方法和系统。 产生多个患者特异性二尖瓣模型，每个来自使用单独成像模态获得的术前图像数据。 来自分开的成像模态的手术前图像数据通过登记多个患者特定模型而融合到公共坐标系中。 使用由多个患者特定模型的登记产生的融合生理学先验在实际的术中图像数据中估计二尖瓣的模型。

公开(公告)号：US08532352B2

公开(公告)日：2013-09-10

申请号：US13267662

申请日：2011-10-06

申请人： Razvan Ioan Ionasec ,  Ingmar Voigt ,  Bogdan Georgescu ,  Yefeng Zheng ,  Jan Boese ,  Klaus Klingenbeck ,  Dorin Comaniciu

发明人： Razvan Ioan Ionasec ,  Ingmar Voigt ,  Bogdan Georgescu ,  Yefeng Zheng ,  Jan Boese ,  Klaus Klingenbeck ,  Dorin Comaniciu

IPC分类号： G06K9/00

CPC分类号： G06T19/006 ,  G06T7/344 ,  G06T17/00 ,  G06T2207/10072 ,  G06T2207/10121 ,  G06T2207/10136 ,  G06T2207/30048 ,  G16H50/50

摘要： A method and system for intraoperative guidance in an off-pump mitral valve repair procedure is disclosed. A plurality of patient-specific models of the mitral valve are generated, each from pre-operative image data obtained using a separate imaging modality. The pre-operative image data from the separate imaging modalities are fused into a common coordinate system by registering the plurality of patient-specific models. A model of the mitral valve is estimated in real-time in intraoperative image data using a fused physiological prior resulting from the registering of the plurality of patient-specific models.

摘要翻译： 公开了一种用于非抽血二尖瓣修复手术中术中引导的方法和系统。 产生多个患者特异性二尖瓣模型，每个来自使用单独成像模态获得的术前图像数据。 来自分开的成像模态的手术前图像数据通过登记多个患者特定模型而融合到公共坐标系中。 使用由多个患者特定模型的登记产生的融合生理学先验在实际的术中图像数据中估计二尖瓣的模型。

公开(公告)号：US20110075798A1

公开(公告)日：2011-03-31

申请号：US12891849

申请日：2010-09-28

申请人： Jan Boese ,  Klaus Klingenbeck

发明人： Jan Boese ,  Klaus Klingenbeck

IPC分类号： G06K9/00 ,  A61B6/03

CPC分类号： A61B6/5241 ,  A61B6/032 ,  A61B6/4441 ,  A61B6/4458 ,  G06T11/005 ,  G06T2211/432

摘要： A method for correcting truncated projection data of a rotation for a reconstruction technique for computed tomography scans with truncated projection data in the computed tomography images produced by a C-arm is proposed. At least one truncated projection is recorded. The truncated portions prior to acquisition of the rotation for the at least one truncated projection is captured. The truncated projection and the truncated portions are assembled into at least one complete projection. Truncated projection data is acquired during the rotation. The truncated data is estimated based on a model of the patient geometry from the at least one complete projection. A reconstruction technique is performed on the basis of the acquired and the estimated data.

摘要翻译： 提出了一种通过C臂产生的计算机断层图像中的截断的投影数据来校正用于计算机断层摄影扫描的重建技术的旋转的截断投影数据的方法。 至少记录一个截断的投影。 捕获用于至少一个截断投影的旋转获取之前的截断部分。 截头突起和截头部分组装成至少一个完整的突起。 截断的投影数据在旋转期间获取。 基于来自至少一个完整投影的患者几何形状的模型来估计截断的数据。 基于获取的和估计的数据执行重建技术。

公开(公告)号：US10390782B2

公开(公告)日：2019-08-27

申请号：US15451575

申请日：2017-03-07

申请人： Klaus Klingenbeck ,  Thomas Redel ,  Michael Scheuering ,  Michael Wiets

发明人： Klaus Klingenbeck ,  Thomas Redel ,  Michael Scheuering ,  Michael Wiets

IPC分类号： A61B6/00 ,  G06T7/11 ,  A61B6/03 ,  G06T7/00 ,  G16H50/50 ,  A61B34/10 ,  A61B5/02

摘要： The disclosure relates to a device and a method for ascertaining at least one individual fluid-dynamic characteristic parameter of a stenosis in a vascular segment having a plurality of serial stenoses, wherein angiography image data of the vascular segment is received from an angiography recording device, geometry data of the vascular segment is ascertained by an analysis device based on the angiography image data and combined into a segment model. At least one division point located between two of the stenoses respectively is ascertained by a dividing device in the segment model, the segment model is subdivided into subsegment models at each of the at least one division points, and the respective fluid-dynamic characteristic parameter is ascertained by a simulation device for at least one of the subsegment models based on respective geometry data of the subsegment model.

公开(公告)号：US08693758B2

公开(公告)日：2014-04-08

申请号：US13094855

申请日：2011-04-27

申请人： Klaus Klingenbeck

发明人： Klaus Klingenbeck

IPC分类号： G06K9/00

CPC分类号： A61B6/481 ,  A61B5/0071 ,  A61B5/0073 ,  A61B5/0084 ,  A61B5/489 ,  A61B5/7425 ,  A61B6/4417 ,  A61B6/4441 ,  A61B6/4458 ,  A61B6/4464 ,  A61B6/485 ,  A61B6/504 ,  A61B6/507 ,  A61B6/5247 ,  A61B8/0816 ,  A61B8/0891 ,  A61B8/4416 ,  A61B8/5238 ,  A61B90/36 ,  A61B2090/364

摘要： An imaging method for enhanced visualization of vessels in an examination region of a patient, in particular during an intervention, is proposed. A 3D reconstruction image of the examination region is generated using a preoperatively recorded 3D image dataset of the examination region. At least one current 2D fluorescence image of the examination region is recorded by a fluorescence angiography. The vessels are identified. The 3D image dataset with the image dataset of the 2D fluorescence or ultrasound image is registered based on the result of the identification. The 3D reconstruction image and the 2D image are overplayed. The overlaid images are 3D played back.

摘要翻译： 提出了一种用于在患者的检查区域，特别是在干预期间增强血管视觉的成像方法。 使用检查区域的术前记录的3D图像数据集来生成检查区域的3D重建图像。 通过荧光血管造影记录检查区域的至少一个当前2D荧光图像。 识别船只。 基于识别结果登记具有2D荧光或超声图像的图像数据集的3D图像数据集。 3D重建图像和2D图像被显示。 重叠的图像是3D回放的。

公开(公告)号：US20110268333A1

公开(公告)日：2011-11-03

申请号：US13094855

申请日：2011-04-27

申请人： Klaus Klingenbeck

发明人： Klaus Klingenbeck

IPC分类号： G06K9/00

CPC分类号： A61B6/481 ,  A61B5/0071 ,  A61B5/0073 ,  A61B5/0084 ,  A61B5/489 ,  A61B5/7425 ,  A61B6/4417 ,  A61B6/4441 ,  A61B6/4458 ,  A61B6/4464 ,  A61B6/485 ,  A61B6/504 ,  A61B6/507 ,  A61B6/5247 ,  A61B8/0816 ,  A61B8/0891 ,  A61B8/4416 ,  A61B8/5238 ,  A61B90/36 ,  A61B2090/364

摘要： An imaging method for enhanced visualization of vessels in an examination region of a patient, in particular during an intervention, is proposed. A 3D reconstruction image of the examination region is generated using a preoperatively recorded 3D image dataset of the examination region. At least one current 2D fluorescence image of the examination region is recorded by a fluorescence angiography. The vessels are identified. The 3D image dataset with the image dataset of the 2D fluorescence or ultrasound image is registered based on the result of the identification. The 3D reconstruction image and the 2D image are overplayed. The overlaid images are 3D played back.

摘要翻译： 提出了一种用于在患者的检查区域，特别是在干预期间增强血管视觉的成像方法。 使用检查区域的术前记录的3D图像数据集来生成检查区域的3D重建图像。 通过荧光血管造影记录检查区域的至少一个当前2D荧光图像。 识别船只。 基于识别结果登记具有2D荧光或超声图像的图像数据集的3D图像数据集。 3D重建图像和2D图像被显示。 重叠的图像是3D回放的。

公开(公告)号：US09031295B2

公开(公告)日：2015-05-12

申请号：US13963265

申请日：2013-08-09

申请人： Klaus Klingenbeck

发明人： Klaus Klingenbeck

IPC分类号： G06K9/00 ,  A61B6/00 ,  A61B6/03

CPC分类号： A61B6/486 ,  A61B6/032 ,  A61B6/4441 ,  A61B6/4458 ,  A61B6/504 ,  A61B6/507 ,  A61B6/5217

摘要： An angiographic method is provided. The method includes: identification of a relevant part in acquired angiography 4D sequences which exhibit a vascular disorder or change; determination of a centerline for the part; ascertainment of lines parallel and surrounding the centerline; specification of perpendicular cross-sections; determination of voxels; ascertainment of bolus curves as a function of time for each voxel; which intersects one of the cross-sections; determination of a time for each voxel; measurement of the true Euclidean distance between voxels at the positions along the centerline and the parallel lines; division of the measured distance by the time difference; determination of second speed components, running transversely, proportional to the relative change in mass for each voxel; and calculation of the blood flow in the relevant part of the vascular system on the basis of the speed components.

摘要翻译： 提供血管造影方法。 该方法包括：鉴定显示血管病变或变化的获得性血管造影4D序列中的相关部分; 确定零件的中心线; 确定线平行并围绕中心线; 垂直截面规格; 体素的确定 确定推注曲线作为每个体素的时间函数; 其与横截面之一相交; 确定每个体素的时间; 在沿着中心线和平行线的位置处的体素之间的真欧几里德距离的测量; 测量距离除以时差; 确定二速组件，横向运行，与每个体素的质量相对变化成比例; 并根据速度分量计算血管系统相关部位的血流量。