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1.发明授权Derivatives of 3-(Guanidinocarbonyl) heterocycle, methods of preparation and intermediates thereof, their use as medicaments, and pharmaceutical compositions therefrom 失效3-（胍基羰基）杂环的衍生物，其制备方法及其中间体，其作为药物的用途及其药物组合物公开(公告)号：US07230007B2
公开(公告)日：2007-06-12
申请号：US10865454
申请日：2004-06-10
申请人： Jean-Christophe Carry , Gilles Doerflinger , Arielle Genevois-Borella , Michel Evers , Alain Le Brun , Jean-Paul Martin , Pascal Desmazeau , Serge Mignani , Heinz-Werner Kleemann
发明人： Jean-Christophe Carry , Gilles Doerflinger , Arielle Genevois-Borella , Michel Evers , Alain Le Brun , Jean-Paul Martin , Pascal Desmazeau , Serge Mignani , Heinz-Werner Kleemann
IPC分类号： A61K31/44 , C07D471/02
CPC分类号： C07D471/04
摘要： The present invention discloses and claims compounds of formula I and their pharmaceutically acceptable salts, and methods of using said compounds of formula I, either alone or in combination with other medicaments, as antiarrhythmic medicaments with a cardioprotective component for prophylaxis or treatment of infarction, for the treatment of angina pectoris, and as inhibitors of pathophysiological processes associated with the development of ischemia-induced damage, in particular in the triggering of ischemia-induced cardiac arrhythmias and of heart failure. Pharmaceutical compositions comprising compounds of formula I or compounds of formula I in combination with one or more other medicaments and processes for the preparation of compounds of formula I are also disclosed and claimed.
摘要翻译： 本发明公开并要求式I化合物及其药学上可接受的盐，以及使用所述式I化合物单独或与其它药物组合的抗心律失常药物与预防或治疗梗死的心脏保护组分的方法，用于 心绞痛的治疗以及与局部缺血诱导的损伤发展相关的病理生理过程的抑制剂，特别是引发缺血诱导的心律失常和心力衰竭。 包含式I化合物或式I化合物与一种或多种其它药物组合的药物组合物和式I化合物的制备方法也被公开并要求保护。
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2.发明申请Derivatives of 3-(guanidinocarbonyl) heterocycle, methods of preparation and intermediates thereof, their use as medicaments, and pharmaceutical compositions therefrom 失效3-（胍基羰基）杂环的衍生物，其制备方法及其中间体，它们作为药物的用途及其药物组合物公开(公告)号：US20050014758A1
公开(公告)日：2005-01-20
申请号：US10865454
申请日：2004-06-10
申请人： Jean-Christophe Carry , Gilles Doerflinger , Arielle Genevois-Borella , Michel Evers , Alain Le Brun , Jean-Paul Martin , Pascal Desmazeau , Serge Mignani , Heinz-Werner Kleemann
发明人： Jean-Christophe Carry , Gilles Doerflinger , Arielle Genevois-Borella , Michel Evers , Alain Le Brun , Jean-Paul Martin , Pascal Desmazeau , Serge Mignani , Heinz-Werner Kleemann
IPC分类号： C07D471/04 , C07D471/02 , A61K31/4745 , A61K31/503 , A61K31/519 , C07D487/02
CPC分类号： C07D471/04
摘要： The present invention discloses and claims compounds of formula I and their pharmaceutically acceptable salts, and methods of using said compounds of formula I, either alone or in combination with other medicaments, as antiarrhythmic medicaments with a cardioprotective component for prophylaxis or treatment of infarction, for the treatment of angina pectoris, and as inhibitors of pathophysiological processes associated with the development of ischemia-induced damage, in particular in the triggering of ischemia-induced cardiac arrhythmias and of heart failure. Pharmaceutical compositions comprising compounds of formula I or compounds of formula I in combination with one or more other medicaments and processes for the preparation of compounds of formula I are also disclosed and claimed.
摘要翻译： 本发明公开并要求式I化合物及其药学上可接受的盐，以及使用所述式I化合物单独或与其它药物组合的抗心律失常药物与预防或治疗梗死的心脏保护组分的方法，用于 心绞痛的治疗以及与局部缺血诱导的损伤发展相关的病理生理过程的抑制剂，特别是引发缺血诱导的心律失常和心力衰竭。 包含式I化合物或式I化合物与一种或多种其它药物组合的药物组合物和式I化合物的制备方法也被公开并要求保护。
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3.发明授权4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them 失效4-取代喹啉衍生物，其制备方法和中间体以及含有它们的药物组合物公开(公告)号：US07232833B2
公开(公告)日：2007-06-19
申请号：US10810711
申请日：2004-03-26
申请人： Antony Bigot , Youssef El-Ahmad , Jean-Luc Malleron , Jean-Paul Martin , Serge Mignani , Guy Pantel , Baptiste Ronan , Michel Tabart , Michel Cheve , Fabrice Viviani
发明人： Antony Bigot , Youssef El-Ahmad , Jean-Luc Malleron , Jean-Paul Martin , Serge Mignani , Guy Pantel , Baptiste Ronan , Michel Tabart , Michel Cheve , Fabrice Viviani
IPC分类号： A61K31/47 , A61K31/517 , A61K31/44 , A61K31/50 , A61K31/54
CPC分类号： C07D401/06 , C07D409/14 , C07D413/06
摘要： The invention relates to 4-substituted quinoline compounds of general formula: which are active as antimicrobials, in which: X1, X2, X3, X4 and X5 is C—R′1, to C—R′5 respectively, or alternatively at most one represents N, Y represents CHR, CO, CROH, CRNH2, CRF or CF2, R being a hydrogen or alkyl, m is 1, 2 or 3 and n is 0, 1 or 2, Z is CH2 or Z is O, S, SO, SO2 and, in this case, n is equal to 2, R2 is —CO2R, —CH2CO2R, —CH2—CH2CO2R, —CH2OH or —CH2—CH2OH, wherein R is as defined above, R3 represents phenyl, heteroaryl or alk-Ro3, where alk is alkyl and Ro3 represents various groups, where appropriate containing oxygen, sulfur or amine, in their enantiomeric or diastereoisomeric forms or their mixtures, and/or where appropriate in the syn or anti form or their mixtures, and their salts.
摘要翻译： 本发明涉及以下通式的4-取代喹啉化合物：其作为抗微生物剂是有活性的，其中：X 1，X 2，X 3， >，X 4和X 5分别为C-R'1，C-R'5， 或者至多一个表示N，Y表示CHR，CO，CROH，CRNH 2，CRF或CF 2，R为氢或烷基，m为1,2 或3，n为0,1或2，Z为CH 2或Z为O，S，SO，SO 2，在这种情况下，n等于 2，R 2是-CO 2 R，-CH 2 CO 2 R，-CH 2， 2个-CH 2 CO 2 R 2，-CH 2 OH或-CH 2 -CH（CH 2） R 2 OH，其中R如上所定义，R 3表示苯基，杂芳基或烷基-SO 3 - ， - 其中烷基是烷基，R 3 O 3表示各种基团，其中适当地含有它们的对映体或非对映异构形式或其混合物中的氧，硫或胺， d /或适当时以合成或反式形式或其混合物及其盐。
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公开(公告)号：US08675066B2
公开(公告)日：2014-03-18
申请号：US12893162
申请日：2010-09-29
申请人： Stephen Scott Trundle , Robert J. McCarthy, Jr. , Jean-Paul Martin , Alison Jane Slavin , David James Hutz
发明人： Stephen Scott Trundle , Robert J. McCarthy, Jr. , Jean-Paul Martin , Alison Jane Slavin , David James Hutz
IPC分类号： H04N7/18
CPC分类号： G08B13/19639 , G08B13/196 , G08B13/19613 , G08B13/19634 , G08B13/1966 , G08B25/008 , G08B25/14 , G08B29/046 , H04N7/183 , H04N7/188
摘要： Image surveillance and reporting technology, in which an event that is indicative of potential physical activity within an area corresponding to a location of a camera unit is detected. In response to detection of the event, the camera unit is controlled to capture one or more images of the area corresponding to the location of the camera unit. The one or more images captured by the camera unit are analyzed to determine whether the one or more images include image data that is indicative of relevant physical activity within the area corresponding to the location of the camera unit. The one or more images are handled based on the determination of whether the one or more images include image data that is indicative of relevant physical activity within the area corresponding to the location of the camera unit.
摘要翻译： 检测图像监视和报告技术，其中检测到指示与相机单元的位置相对应的区域内潜在的身体活动的事件。 响应于事件的检测，控制相机单元以捕获与相机单元的位置相对应的区域的一个或多个图像。 分析由相机单元捕获的一个或多个图像，以确定一个或多个图像是否包括指示与相机单元的位置相对应的区域内的相关身体活动的图像数据。 基于确定一个或多个图像是否包括指示在与相机单元的位置相对应的区域内的相关身体活动的图像数据来处理一个或多个图像。
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公开(公告)号：US08531294B2
公开(公告)日：2013-09-10
申请号：US12782668
申请日：2010-05-18
IPC分类号： G08B13/00
CPC分类号： G08B13/2462 , G08B13/2402 , G08B13/2491 , G08B21/18 , G08B25/008 , G08B25/14
摘要： Techniques are described for moving asset location tracking and monitoring system technology. A system monitors for events related to a monitoring system that monitors a fixed property and the system detects an event related to the monitoring system based on the monitoring. The system performs an operation that leverages geographic location tracking of at least one mobile asset associated with the fixed property based on the detected event.
摘要翻译： 描述了移动资产定位跟踪和监控系统技术的技术。 系统监视与监控系统相关的事件，监控系统监控固定属性，系统会根据监控情况检测与监控系统有关的事件。 该系统基于检测到的事件执行利用与固定属性相关联的至少一个移动资产的地理位置跟踪的操作。
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公开(公告)号：US08493202B1
公开(公告)日：2013-07-23
申请号：US13053994
申请日：2011-03-22
IPC分类号： G08B23/00
CPC分类号： G08B29/046 , G08B25/005 , G08B25/006 , G08B25/008 , G08B29/02 , G08B29/185
摘要： Techniques are described for handling an event where a control panel or an alarm signaling device is tampered with or destroyed by a disablement tactic, e.g., a “crash and smash intrusion.”
摘要翻译： 描述了用于处理事件的技术，其中控制面板或警报信号装置被诸如“崩溃和粉碎入侵”的禁用策略篡改或破坏。
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公开(公告)号：US08467763B2
公开(公告)日：2013-06-18
申请号：US13403082
申请日：2012-02-23
IPC分类号： H04M11/04
摘要： Techniques are described for establishing a two-way voice communication session with an alarm system. The alarm system may establish a two-way voice communication session with an operator associated with a monitoring service that provides monitoring services for alarm events detected by the alarm system. The alarm system also may establish a two-way voice communication session with a notification recipient that is interested in receiving notifications associated with events detected by the alarm system.
摘要翻译： 描述了用于与报警系统建立双向语音通信会话的技术。 报警系统可以与与监控服务相关联的运营商建立双向语音通信会话，监控服务为报警系统检测到的报警事件提供监控服务。 报警系统还可以与有兴趣接收与由报警系统检测到的事件有关的通知的通知接收者建立双向语音通信会话。
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公开(公告)号：US08395494B2
公开(公告)日：2013-03-12
申请号：US12615318
申请日：2009-11-10
CPC分类号： G08B29/02 , G08B25/002 , G08B25/10 , G08B29/00 , G08B29/046 , G08B29/16 , G08B29/185
摘要： A system and method provide for the immediate transmission of a potential alarm to a remote alarm signal escrow site and from the escrow site to a host station in the event where a control panel or an alarm signaling device is tampered with or destroyed by a disablement tactic, e.g., a “crash and smash intrusion.” A system and method may also send an alarm signal during such an attack by using predictive analysis of real-time events.
摘要翻译： 一种系统和方法提供了一种潜在的警报信号到远距离的报警信号保管站点，并且在控制面板或报警信号装置被禁用或被破坏的情况下，从托管站点传送到主机站 例如，崩溃和粉碎入侵。 系统和方法还可以通过使用实时事件的预测分析在这种攻击期间发送报警信号。
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公开(公告)号：US08022807B2
公开(公告)日：2011-09-20
申请号：US11871936
申请日：2007-10-12
摘要： Techniques are described for establishing a two-way voice communication session with an alarm system. The alarm system may establish a two-way voice communication session with an operator associated with a monitoring service that provides monitoring services for alarm events detected by the alarm system. The alarm system also may establish a two-way voice communication session with a notification recipient that is interested in receiving notifications associated with events detected by the alarm system.
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公开(公告)号：US20100289643A1
公开(公告)日：2010-11-18
申请号：US12782626
申请日：2010-05-18
CPC分类号： G05B15/02 , F24F11/30 , F24F11/52 , F24F2110/10 , F24F2120/10 , F24F2130/00 , F24F2130/10 , F24F2140/60 , G08C19/16 , H04L12/282
摘要： Techniques are described for providing remote device (e.g., thermostat, lighting, appliance, etc.) control and/or energy monitoring. A system monitors sensor data captured by one or more sensors that sense attributes relevant to user presence at one or more monitored properties and status of one or more energy consuming devices associated with the one or more monitored properties. The system analyzes the monitored sensor data and the monitored device status with respect to a set of one or more rules and performs an operation related to controlling the one or more energy consuming devices based on the analysis of the monitored sensor data and the monitored device status with respect to the set of one or more rules.
摘要翻译： 描述了用于提供远程设备（例如，恒温器，照明，设备等）控制和/或能量监测的技术。 系统监视由一个或多个传感器捕获的传感器数据，所述传感器感测与一个或多个被监控属性相关联的一个或多个能量消耗装置的一个或多个监视属性和状态的与用户存在相关的属性。 该系统相对于一组一个或多个规则来分析所监测的传感器数据和所监视的设备状态，并且基于对所监视的传感器数据的分析和所监视的设备状态执行与控制一个或多个能量消耗设备相关的操作 关于一套或多项规则。
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