利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

34 条记录 (耗时 0.07 秒)

    METHOD OF SAMPLING AND/OR DEPOSITING A SAMPLE OF BIOLOGICAL MATTER AND DEVICE IMPLEMENTING SUCH A METHOD
    1.
    发明申请
    METHOD OF SAMPLING AND/OR DEPOSITING A SAMPLE OF BIOLOGICAL MATTER AND DEVICE IMPLEMENTING SUCH A METHOD 有权
    采样和/或沉积生物学样本的方法和实现方法的装置

    公开(公告)号：US20130109047A1

    公开(公告)日：2013-05-02

    申请号：US13808501

    申请日：2011-07-08

    申请人： Jean-Philippe Charrier ,  Bruno Colin ,  Laurent Drazek ,  Cécile Paris ,  Jean-Claude Raymond ,  Dominique Decaux

    发明人： Jean-Philippe Charrier ,  Bruno Colin ,  Laurent Drazek ,  Cécile Paris ,  Jean-Claude Raymond ,  Dominique Decaux

    IPC分类号： C12Q1/24

    CPC分类号： C12Q1/24 ,  C12M33/04

    摘要： The aim of the present invention is a method of sampling all or part of a sample (11) of biological matter (7), which is crude, enriched or cultured through contact with a culture medium (8), such as agar, for example in a Petri dish, using a probe (3) equipped with a terminal end (4), said sampling method comprising the steps of cooling the terminal end (4) of the probe (3), sticking all or part of the sample (11) of biological matter (7) to be sampled through contact, or by applying a pressure exerted by the terminal end (4) onto the sample (11) of biological matter (7), and sampling of all or part of the sample (11) of biological matter (7) so as to separate the sample (11) of biological matter (7) from the culture medium (8), a method of depositing into a container (9) or onto an analysis plate (14) all or part of a sample (11) of biological matter (7) stuck onto a frosted terminal end (4) of a probe, said depositing method including a step of separating the terminal end (4) of the probe (3) from all or part of the sample (11) of biological matter (7), as well as a device (2), a kit and an apparatus (1) implementing these methods.

    摘要翻译： 本发明的目的是对生物物质（7）的全部或部分样品（11）进行取样的方法，其通过与诸如琼脂的培养基（8）接触而粗制，富集或培养。 在陪替氏培养皿中，使用配备有终端（4）的探针（3），所述取样方法包括冷却探针（3）的末端（4）的步骤，将全部或部分样品（11 ），或通过将终端（4）施加的压力施加到生物物质（7）的样品（11）上，并对样品（11）的全部或部分进行采样 ）将生物物质（7）的样品（11）与培养基（8）分离，将沉积到容器（9）或分析板（14）中的全部或者 将生物物质（7）的样品（11）的一部分粘贴到探针的磨砂末端（4）上，所述沉积方法包括将所述末端（4） 来自生物物质（7）的全部或部分样品（11）的探针（3）以及实施这些方法的装置（2），试剂盒和装置（1）。

    NOVEL METHOD FOR QUANTIFYING PROTEINS BY MASS SPECTROMETRY
    8.
    发明申请
    NOVEL METHOD FOR QUANTIFYING PROTEINS BY MASS SPECTROMETRY 有权
    通过质谱法定量蛋白质的新方法

    公开(公告)号：US20120208224A1

    公开(公告)日：2012-08-16

    申请号：US13322173

    申请日：2010-05-21

    申请人： Jérôme Lemoine ,  Arnaud Salvador ,  Jean-Philippe Charrier ,  Tanguy Fortin

    发明人： Jérôme Lemoine ,  Arnaud Salvador ,  Jean-Philippe Charrier ,  Tanguy Fortin

    IPC分类号： G01N27/62

    CPC分类号： G01N33/6848

    摘要： The present invention relates to a method for the quantitative detection of a target protein in a sample, in which the second-generation fragment ions are detected for providing a series of quantitative measurements, at least one of which is correlated to the amount of proteotypic peptide generated and to the amount of target protein in the sample, characterized in that the selected first-generation fragment ion having a mass (m/z)2 is a doubly-charged peptide having a proline and/or a histidine in position 1.

    摘要翻译： 本发明涉及用于定量检测样品中靶蛋白的方法，其中检测第二代碎片离子以提供一系列定量测量，其中至少一种与蛋白多肽的量相关 产生和样品中靶蛋白的量，其特征在于所选择的具有质量（m / z）2的第一代碎片离子是位置1具有脯氨酸和/或组氨酸的双电荷肽。