公开(公告)号：US07148382B2

公开(公告)日：2006-12-12

申请号：US10485836

申请日：2002-08-13

申请人： Jean-Pierre Wolf ,  Gebhard Hug

发明人： Jean-Pierre Wolf ,  Gebhard Hug

IPC分类号： C07F9/02

CPC分类号： C07F9/3252 ,  B33Y70/00 ,  C07F9/5337 ,  C07F9/572 ,  C07F9/6533 ,  C08F2/50 ,  G03F7/029

摘要： Compounds of formula (I), wherein A is S or O; x is 0 or 1; a is SR10 or N(R11)(R12); R1 and R2 are C1–C24alkyl, OR10, CF3 or halogen; R3, R4 and R5 are hydrogen, C1–C24alkyl, OR10 or halogen; or two of the radicals R11 R21 R31 R4 and/or R9 together form C1–C2oalkylene uninterrupted or interrupted by O, S or NR13; R6, R11 R8 and R9 are hydrogen, C1–C24alkyl; C2–C24alkyl which is interrupted one or more times by non-consecutive O atoms and unsubstituted or substituted by OH and/or SH, or R6, R7, R8 and Rg are OR10; halogen; or phenyl unsubstituted or substituted one or more times by C-Calkyl; R10, R11 and R12 are e.g. hydrogen; X is e.g. (II), and R2; have one of the meanings given for R1 and R2; and R3′, R4′ and Rs′ have one of the meanings given for R3, R4 and R5; are suitable as photoinitiators, especially for irradiation with light of relatively long wavelengths

摘要翻译： 式（I）的化合物，其中A是S或O; x为0或1; a是SR 10或N（R 11）（R 12）; R 1和R 2都是C 1 -C 24烷基，或者R 10是C 1 -C 12烷基， CF 3或卤素; R 3，R 4和R 5是氢，C 1 -C 24 烷基，OR 10或卤素; 或两个基团R 11，R 21，R 31，R 4和/或R 9， / SUB>一起形成C 1〜C 2亚烷基，其不被中断或被O，S或NR 13中断。 R 6，R 11，R 8和R 9是氢，C 1〜 -C 24烷基; C 2 -C 24烷基，其被不连续的O原子间隔一个或多个，未被取代或被OH和/或SH取代，或R 6 R 7，R 8和R 8是OR 10; 卤素; 或被C-C烷基未被取代或取代一次或多次的苯基; R 10，R 11和R 12是例如R 11和R 12。 氢; X是例如 （II）和R 2; 具有R 1和R 2 2给出的含义之一; 和R 3'，R 4'和R''具有R 3，R 4，R 3， >和R 5; 适合作为光引发剂，特别是对于具有较长波长的光的照射

公开(公告)号：US06969733B2

公开(公告)日：2005-11-29

申请号：US10280820

申请日：2002-10-25

申请人： Jean-Pierre Wolf ,  Gebhard Hug

发明人： Jean-Pierre Wolf ,  Gebhard Hug

IPC分类号： A61K6/00 ,  C07F1/02 ,  C07F9/28 ,  C07F9/50 ,  C07F9/53 ,  C07F9/655 ,  C07F19/00 ,  C08F2/46 ,  C08F2/50 ,  C08F4/00 ,  C08F4/08 ,  C08K5/5397 ,  C09D4/00 ,  C09D5/00 ,  C09D5/03 ,  C09D7/12 ,  C09D11/101 ,  C09D201/02 ,  C09J4/00 ,  C09J11/06 ,  C09J201/02 ,  G03F7/004 ,  G03F7/029 ,  G03F7/038 ,  C08K3/20

CPC分类号： G03F7/029 ,  A61K6/0052 ,  B33Y70/00 ,  C07F9/28 ,  C07F9/5036 ,  C07F9/5337 ,  C07F9/65502 ,  C08F2/46 ,  C08K5/5397 ,  C09D11/101 ,  G03F7/0045 ,  G03F7/038 ,  G03F7/0384 ,  G03F7/0388 ,  Y10T428/26 ,  Y10T428/31504

摘要： Compounds of the formula I (I), in which Ar is a group or unsubstituted or substituted cyclopentyl, cyclohexyl, naphthyl, biphenylyl or an O-, S- or N-containing 5- or 6-membered heterocyclic ring; R1 and R2 are C1-C20alkyl, OR11, CF3 or halogen; R3, R4 and R5 are hydrogen, C1-C20alkyl, OR11 or halogen; R6 is unsubstituted or substituted C1-C24alkyl, C2-C24alkyl, which is interrupted by O, S or NR14 and is unsubstituted or substituted; C2-C24alkenyl, uninterrupted or interrupted by O, S or NR14 and unsubstituted or substituted; unsubstituted or substituted C7-C24arylalkyl; C4-C24cycloalkyl, uninterrupted or interrupted by O, S and/or NR14; or C8-C24arylcycloalkyl; R11 is C1-C20alkyl, C3-C8cycloalkyl, phenyl, benzyl or C2-C20alkyl, interrupted by O or S and unsubstituted or substituted; R12 and R13 are hydrogen, C1-C20alkyl, C3-C8cycloalkyl, phenyl, benzyl or C2-C20alkyl, interrupted by O atoms and unsubstituted or substituted; or R12 and R13 together are C3-C5alkylene, uninterrupted or interrupted by O, S, or NR14; R14 is hydrogen, phenyl, C1-C12alkyl or C2-C12alkyl, interrupted by O or S and unsubstituted or substituted; and M is hydrogen, Li, Na or K; are valuable intermediates for the preparation of unsymmetrical bisacylphosphine oxides and monoacylphosphine oxides.

公开(公告)号：US07026017B2

公开(公告)日：2006-04-11

申请号：US10280819

申请日：2002-10-25

申请人： Jean-Pierre Wolf ,  Gebhard Hug

发明人： Jean-Pierre Wolf ,  Gebhard Hug

IPC分类号： G03F7/031 ,  C08F2/50 ,  C07F9/28 ,  C07F9/50 ,  C07F9/53

CPC分类号： G03F7/029 ,  A61K6/0052 ,  B33Y70/00 ,  C07F9/28 ,  C07F9/5036 ,  C07F9/5337 ,  C07F9/65502 ,  C08F2/46 ,  C08K5/5397 ,  C09D11/101 ,  G03F7/0045 ,  G03F7/038 ,  G03F7/0384 ,  G03F7/0388 ,  Y10T428/26 ,  Y10T428/31504

摘要： Compounds of the formula I in which Ar is a group or unsubstituted or substituted cyclopentyl, cyclohexyl, naphthyl, biphenylyl or an O-, S- or N-containing 5- or 6-membered heterocyclic ring; R1 and R2 are C1-C20alkyl, OR11, CF3 or halogen; R3, R4 and R5 are hydrogen, C1-C20alkyl, OR11 or halogen; R6 is unsubstituted or substituted C1-C24alkyl, C2-C24alkyl, which is interrupted by O, S or NR14 and is unsubstituted or substituted; C2-C24alkenyl, uninterrupted or interrupted by O, S or NR14 and unsubstituted or substituted; unsubstituted or substituted C7-C24arylalkyl; C4-C24cycloalkyl, uninterrupted or interrupted by O, S and/or NR14; or C8-C24arylcycloalkyl; R11 is C1-C20alkyl, C3-C8cycloalkyl, phenyl, benzyl or C2-C20alkyl, interrupted by O or S and unsubstituted or substituted; R12 and R13 are hydrogen, C1-C20alkyl, C3-C8cycloalkyl, phenyl, benzyl or C2-C20alkyl, interrupted by O atoms and unsubstituted or substituted; or R12 and R13 together are C3-C5alkylene, uninterrupted or interrupted by O, S or NR14; R14 is hydrogen, phenyl, C1-C12alkyl or C2-C12alkyl, interrupted by O or S and unsubstituted or substituted; and M is hydrogen, Li, Na or K; are valuable intermediates for the preparation of unsymmetrical bisacylphosphine oxides and monoacylphosphine oxides.

公开(公告)号：US07196228B2

公开(公告)日：2007-03-27

申请号：US10517231

申请日：2003-06-03

申请人： Jean-Pierre Wolf ,  Gebhard Hug

发明人： Jean-Pierre Wolf ,  Gebhard Hug

IPC分类号： C07F9/02

CPC分类号： C07F9/28 ,  B33Y70/00 ,  C07F9/5337 ,  C07F9/65685 ,  C08F2/50 ,  G03F7/029

摘要： The invention relates to dimer and multimer form of BAPO compounds of the formula (I) dimer and multimer forms of MAPO compounds of the formula (II) wherein R1, R2, and R3 independently of one another are unsubstituted or substituted C1–C12alkyl, benzyl, C1–C12alkoxy, C3–C6cycloalkyl or C5–C14aryl; Q is a di- tri or tetravalent arylene residue; n is 1–4, m is 0–2, n+m is 2, 3 or 4, with the proviso, that R1 and R3 are different from each other. The invention further relates to a process for the preparation of dimer or multimer forms of BAPO compounds of the formula (I) and of dimer or multimer forms of MAPO compounds of the formula (II), characterized in the (n+m) equivalents of a dimetalated-phosphine R1P(M)2 is reacted with one equivalent of a di- or polycarboxylic acid halogenide to form an intermediate of the formula III the intermediate is then reacted either with (n+m) equivalents of a further carboxylic acid halogenide (R2—CO-Hal) or with a halogenide R3-Hal, the reaction products are then oxidized to form phosphine oxides of the formula I or II

摘要翻译： 本发明涉及式（I）的二聚体和多聚体形式的BAPO化合物二聚体和式（II）的MAPO化合物的多聚体形式，其中R 1，R 2， R 3和R 3彼此独立地是未取代的或取代的C 1 -C 12烷基，苄基，C 1〜 C 12 -C 12烷氧基，C 3 -C 6环烷基或C 5 -C 14烷基， / SUB>芳基; Q是二或四价亚芳基; n为1-4，m为0-2，n + m为2,3或4，条件是R 1和R 3各自不同 其他。 本发明还涉及制备式（I）的二聚体或多聚体形式的BAPO化合物和式（II）的MAPO化合物的二聚体或多聚体形式的方法，其特征在于（n + m）当量的 二（二） - 膦R 1 P（M）2 N与1当量的二元或多元羧酸卤化物反应形成式Ⅲ的中间体，然后将中间体 与（n + m）当量的另外的羧酸卤化物（R 2 SO 2 -CO-Hal）或与卤化物R 3 -Hal反应，反应产物为 然后氧化形成式I或II的氧化膦

公开(公告)号：US07109250B2

公开(公告)日：2006-09-19

申请号：US10495958

申请日：2002-11-13

申请人： Jean-Pierre Wolf ,  Gebhard Hug

发明人： Jean-Pierre Wolf ,  Gebhard Hug

IPC分类号： C08F2/50 ,  G03F7/029 ,  C07F9/53 ,  C07F9/58 ,  C03C25/10

CPC分类号： G03F7/029 ,  B33Y70/00 ,  C07F9/5036 ,  C07F9/5337 ,  C07F9/58 ,  C08F2/50

摘要： Compounds of the formula (I), in which E is O or S; and x is 0 or 1, A is cyclopentyl, cyclohexyl, naphthyl, biphenylyl, anthracyl or an O-, S- or N-containing 5- or 6-membered heterocyclic ring, where the mentioned radicals are unsubstituted or substituted by halogen, C1–C4alkyl or C1–C4alkoxy; or A is a group formula (II) R is C1–C24alkyl, unsubstituted or substituted, C2–C24alkyl which is interrupted once or more than once by nonconsecutive O, S or NR14 and which is unsubstituted or substituted, C2–C24alkenyl which is uninterrupted or interrupted once or more than once by nonconsecutive O, S or NR14 and which is unsubstituted or substituted, C5–C24cycloalkenyl which is uninterrupted or interrupted once or more than once by nonconsecutive O, S or NR14 and which is unsubstituted or substituted; C7–C24arylalkyl which is unsubstituted or substituted on the aryl group. C4–C24cycloalkyl which is uninterrupted or interrupted once or more then once by O, S or NR14 and which is unsubstituted or substituted, C8–C24arylcycloalkyl or C8–C24arylcycloalkenyl; or, R is a group of the formula (III) W is a bond, —CO—O— or —CO—N(R15)—; L a di-tri-or tetravalent linking group, n is a number of 2,3 or 4;

摘要翻译： 式（I）化合物，其中E为O或S; 并且x是0或1，A是环戊基，环己基，萘基，联苯基，蒽基或O-，S-或N-的5-或6-元杂环，其中所述基团是未取代的或被卤素取代，C C 1 -C 4烷基或C 1 -C 4烷氧基; C 1 -C 4烷基或C 1 -C 4烷氧基; 或A为基团式（II）R为C 1 -C 24烷基，未取代或取代的C 2 -C 14烷基， 24烷基，其被非连续的O，S或NR 14中断一次或多于一次，并且是未取代或取代的C 2 -C 2烷基， 24个不连续或间断的一个或多个不连续的O，S或NR 14的链烯基，其未被取代或被取代，C 5 -C 不连续的或不间断的一个或多个不连续的O，S或NR 14的未被取代或未被取代的环烯基; 未取代或在芳基上取代的C 7 -C 24芳基烷基。 C 4或C 14环烷基，其被未被取代或被取代的未被取代或未被取代 ，C 8 -C 24芳基环烷基或C 8 -C 20芳基环烯基; 或者，R为式（III）的基团，W为键，-CO-O-或-CO-N（R 15） - ; L为二价或四价连接基团，n为2,3或4;

公开(公告)号：US20050004247A1

公开(公告)日：2005-01-06

申请号：US10495958

申请日：2002-11-13

申请人： Jean-Pierre Wolf ,  Gebhard Hug

发明人： Jean-Pierre Wolf ,  Gebhard Hug

IPC分类号： C03C25/10 ,  C07F9/50 ,  C07F9/53 ,  C07F9/58 ,  C08F2/46 ,  C08F2/50 ,  C08F10/00 ,  G03F7/029 ,  C08J3/28

CPC分类号： G03F7/029 ,  B33Y70/00 ,  C07F9/5036 ,  C07F9/5337 ,  C07F9/58 ,  C08F2/50

摘要： Compounds of the formula (I), in which E is O or S; and x is 0 or 1, A is cyclopentyl, cyclohexyl, naphthyl, biphenylyl, anthracyl or an O—,S— or N-containing 5- or 6-membered heterocyclic ring, where the mentioned radicals are unsubstituted or substittuded by halogen, C1-C4alkyl or C1-C4alkoxy; or A is a group formula (II) R is C1-C24alkyl, unsubstituted or substituted, C2-C24alkyl which is interrupted once or more than once by nonconsecutive O, S or NR14 and which is unsubstituted or substituted, C2-C24alkenyl which is uninterrupted or interrupted once or more than once by nonconsecutive O, S or NR14 and which is unsubstituted or substituted, C5-C24cycloalkenyl which is uninterrupted or interrupted once or more than once by nonconsecutive O, S or NR14 and which is unsubstituted or substituted: C7-C24arylalkyl which is unsubstituted or substituted on the aryl group. C4-C24cycloalkyl which is uninterrupted or interrupted once or more then once by O, S or NR14 and which is unsubstituted or substituted, C8-C24arylcycloalkyl or C8-C24arylcycloalkenyl; or, R is a group of the formula (III) W is a bond, —CO—O— or —CO—N(R15)—; L is a di-tri-or tetravalent linking group, n is a number of 2,3 or 4;

摘要翻译： 式（I）化合物，其中E为O或S; 并且x是0或1，A是环戊基，环己基，萘基，联苯基，蒽基或O-，S-或N-的5-或6-元杂环，其中所述基团是未取代的或被卤素取代的C1， -C 1-4烷基或C 1 -C 4烷氧基; 或者A是基团式（II）R是C1-C24烷基，未取代或取代的C2-C24烷基，其被不连续的O，S或NR 14中断一次或多于一次，并且是未被取代或取代的，不中断的C 2 -C 24链烯基 或非连续的O，S或NR14中断一次或多于一次，并且其是未连接的或未被取代的C 1 -C 24环烯基，其被不连续的或不间断地被不连续的O，S或NR 14中断或中断，并且未被取代或被取代：C7- 未取代或在芳基上取代的C24芳烷基。 C 1 -C 24环烷基，其被未被取代或取代的C 8 -C 24芳基环烷基或C 8 -C 24芳基环烯基不间断或中断一次或多于一次， 或者，R为式（III）的基团，W为键，-CO-O-或-CO-N（R 15） - ; L是二 - 或四价连接基团，n是2,3或4的数;

公开(公告)号：US06579663B2

公开(公告)日：2003-06-17

申请号：US10037111

申请日：2001-10-22

申请人： Jean-Pierre Wolf ,  Beat Michael Aebli ,  Gebhard Hug

发明人： Jean-Pierre Wolf ,  Beat Michael Aebli ,  Gebhard Hug

IPC分类号： G03F7027

CPC分类号： C09D11/101 ,  A61K6/0052 ,  A61K6/08 ,  B33Y70/00 ,  C07F9/28 ,  C07F9/5036 ,  C07F9/5337 ,  C07F9/6521 ,  C08F2/50 ,  C09D4/00 ,  G03F7/0045 ,  G03F7/029 ,  G03F7/0384 ,  G03F7/0388 ,  G03F7/0755 ,  Y10S430/124 ,  A61K6/083 ,  C08L33/08 ,  C08L33/10 ,  C08L33/20 ,  C08L33/26 ,  C08L27/00 ,  C08L31/04 ,  C08L25/06 ,  C08L27/04 ,  C08L39/06 ,  A61K6/09 ,  C08L75/04 ,  A61K6/087 ,  C08L67/00 ,  C08L71/02 ,  A61K6/097 ,  C08L1/08

摘要： Compounds of the formula I R1 and R2 independently of one another are C1-C20alkyl, OR11, CF3 or halogen; R3, R4 and R5 independently of one another are hydrogen, C1-C20alkyl, OR11 or halogen; R6, R7, R8, R9 and R10 independently of one another are hydrogen, C1-C20alkyl; C2-C20alkyl which is interrupted once or more than once by nonconsecutive O atoms and which is unsubstituted or substituted by OH and/or SH; or R6, R7, R8, R9 and R10 are OR11, SR11, N(R12)(R13), phenyl or halogen; R11 is C1-C20alkyl, C3-C8cycloalkyl, phenyl, benzyl or C2-C20alkyl which is interrupted once or more than once by O or S and which is unsubstituted or substituted by OH and/or SH; R12 and R13 independently of one another are hydrogen, C114 C20alkyl, C3-C8cycloalkyl, phenyl, benzyl or C2-C20alkyl which is interrupted once or more than once by nonconsecutive O atoms and which is unsubstituted or substituted by OH and/or SH; or R12 and R13 together are C3-C5alkylene which can be interrupted by O, S or NR14; R14 is hydrogen, phenyl, C1-C12alkyl or C2-C12alkyl which is interrupted once or more than once by O or S and which is unsubstituted or substituted by OH and/or SH; and M is hydrogen, Li, Na or K; are valuable intermediates for the preparation of unsymmetrical bisacylphosphine oxides and monoacylphosphine oxides.

摘要翻译： 式IR1和R2的化合物彼此独立地为C1-C20烷基，OR11，CF3或卤素; R 3，R 4和R 5彼此独立地是氢，C 1 -C 20烷基，OR 11或卤素; R 6，R 7，R 8，R 9和R 10彼此独立地是氢，C 1 -C 20烷基; 被不连续的O原子中断一次或多于一次且未被取代或被OH和/或SH取代的C 2 -C 20烷基; 或R 6，R 7，R 8，R 9和R 10为OR 11，SR 11，N（R 12）（R 13），苯基或卤素; R 11是被O或S间隔一次或多于一次并且未被取代或被OH和/或SH取代的C 1 -C 20烷基，C 3 -C 8环烷基，苯基，苄基或C 2 -C 20烷基。 R 12和R 13彼此独立地是氢，C 11-14 C20烷基，C 3 -C 8环烷基，苯基，苄基或C 2 -C 20烷基，其被非连续的O原子间隔一次或多于一次，并且是未取代的或被OH和/或SH取代; 或R 12和R 13一起是可被O，S或NR14中断的C 3 -C 5亚烷基; R 14是氢，苯基，C 1 -C 12烷基或C 2 -C 12烷基，其被O或S间隔一次或多于一次，并且是未取代的或被OH和/或SH取代; M为氢，Li，Na或K; 是制备不对称双酰基氧化膦和单酰基氧化膦的有价值的中间体。

公开(公告)号：US20050245768A1

公开(公告)日：2005-11-03

申请号：US10517231

申请日：2003-06-03

申请人： Jean-Pierre Wolf ,  Gebhard Hug

发明人： Jean-Pierre Wolf ,  Gebhard Hug

IPC分类号： C07F9/28 ,  C07F9/53 ,  C07F9/6568 ,  C08F2/50 ,  G03F7/029 ,  C07F9/02

CPC分类号： C07F9/28 ,  B33Y70/00 ,  C07F9/5337 ,  C07F9/65685 ,  C08F2/50 ,  G03F7/029

摘要： The invention relates to dimer and multimer form of BAPO compounds of the formula (I) dimer and multimer forms of MAPO compounds of the formula (II) wherein R1, R2, and R3 independently of one another are unsubstituted or substituted C1-C12alkyl, benzyl, C1-C12alkoxy, C3-C6cycloalkyl or C5-C14aryl; Q is a di-tri or tetravalent arylene residue; n is 1-4, m is 0-2, n+m is 2, 3 or 4, with the proviso, that R1 and R3 are different from each other. The invention further relates to a process for the preparation of dimer or multimer forms of BAPO compounds of the formula (I) and of dimer or multimer forms of MAPO compounds of the formula (II), characterized in the (n+m) equivalents of a dimetalated-phosphine R1P(M)2 is reacted with one equivalent of a di- or polycarboxylic acid halogenide to form an intermediate of the formula III the intermediate is then reacted either with (n+m) equivalents of a further carboxylic acid halogenide (R2—CO-Hal) or with a halogenide R3-Hal, the reaction products are then oxidized to form phosphine oxides of the formula I or II.

摘要翻译： 本发明涉及式（I）的二聚体和多聚体形式的BAPO化合物二聚体和式（II）的MAPO化合物的多聚体形式，其中R 1，R 2， R 3和R 3彼此独立地是未取代的或取代的C 1 -C 12烷基，苄基，C 1〜 C 12 -C 12烷氧基，C 3 -C 6环烷基或C 5 -C 14烷基， / SUB>芳基; Q是二价或四价的亚芳基; n为1-4，m为0-2，n + m为2,3或4，条件是R 1和R 3各自不同 其他。 本发明还涉及制备式（I）的二聚体或多聚体形式的BAPO化合物和式（II）的MAPO化合物的二聚体或多聚体形式的方法，其特征在于（n + m）当量的 二（二） - 膦R 1 P（M）2 N与1当量的二元或多元羧酸卤化物反应形成式Ⅲ的中间体，然后将中间体 与（n + m）当量的另外的羧酸卤化物（R 2 SO 2 -CO-Hal）或与卤化物R 3 -Hal反应，反应产物为 然后氧化形成式I或II的氧化膦。

公开(公告)号：US06737549B2

公开(公告)日：2004-05-18

申请号：US09871373

申请日：2001-05-31

申请人： Jean-Pierre Wolf ,  Gebhard Hug

发明人： Jean-Pierre Wolf ,  Gebhard Hug

IPC分类号： C07F902

CPC分类号： G03F7/029 ,  A61K6/0052 ,  B33Y70/00 ,  C07F9/28 ,  C07F9/5036 ,  C07F9/5337 ,  C07F9/65502 ,  C08F2/46 ,  C08K5/5397 ,  C09D11/101 ,  G03F7/0045 ,  G03F7/038 ,  G03F7/0384 ,  G03F7/0388 ,  Y10T428/26 ,  Y10T428/31504

摘要： Compounds of the formula I Ar is a group or unsubstituted or substituted cyclopentyl, cyclohexyl, naphthyl, biphenylyl or an O-, S- or N-containing 5- or 6-membered heterocyclic ring; R1 and R2 are C1-C20alkyl, OR11, CF3 or halogen; R3, R4 and R5 are hydrogen, C1-C20alkyl, OR11 or halogen; R6 is unsubstituted or substituted C1-C24alkyl, C2-C24alkyl, which is interrupted by O, S or NR14 and is unsubstituted or substituted; C2-C24alkenyl, uninterrupted or interrupted by O, S or NR14 and unsubstituted or substituted; unsubstituted or substituted C7-C24arylalkyl; C4-C24cycloalkyl, uninterrupted or interrupted by O, S and/or NR14; or C8-C24arylcycloalkyl; R11 is C1-C20alkyl, C3-C8cycloalkyl, phenyl, benzyl or C2-C20alkyl, interrupted by O or S and unsubstituted or substituted; R12 and R13 are hydrogen, C1-C20alkyl, C3-C8cycloalkyl, phenyl, benzyl or C2-C20alkyl, interrupted by O atoms and unsubstituted or substituted; or R12 and R13 together are C3-C5alkylene, uninterrupted or interrupted by O, S or NR14; R14 is hydrogen, phenyl, C1-C12alkyl or C2-C12alkyl, interrupted by O or S and unsubstituted or substituted; and M is hydrogen, Li, Na or K; are valuable intermediates for the preparation of unsymmetrical bisacylphosphine oxides and monoacylphosphine oxides.

摘要翻译： 式IAr的化合物是未取代或取代的环戊基，环己基，萘基，联苯基或含O-，S-或N的5-或6-元杂环的基团; R1和R2是C1-C20烷基，OR11，CF3或卤素; R3，R4和R5是氢，C1-C20烷基，OR11或卤素; R6是未取代的或被O，S或NR14中断的未取代或取代的C 1 -C 24烷基，C 2 -C 24烷基， C2-C24链烯基，不间断或被O，S或NR14中断，未取代或取代的; 未取代或取代的C 7 -C 24芳烷基; C 1 -C 24环烷基，不间断或被O，S和/或NR 14中断; 或C 8 -C 24芳基环烷基; R11是被O或S间隔的未取代或取代的C1-C20烷基，C3-C8环烷基，苯基，苄基或C2-C20烷基; R 12和R 13是氢，C 1 -C 20烷基，C 3 -C 8环烷基，苯基，苄基或C 2 -C 20烷基，被O原子间隔并且是未取代或取代的; 或R 12和R 13一起是C 3 -C 5亚烷基，不间断或被O，S或NR 14中断; R 14是被O或S间隔的未取代或取代的氢，苯基，C 1 -C 12烷基或C 2 -C 12烷基; M为氢，Li，Na或K; 是制备不对称双酰基氧化膦和单酰基氧化膦的有价值的中间体。

公开(公告)号：US06399805B2

公开(公告)日：2002-06-04

申请号：US09776657

申请日：2001-02-05

申请人： Jean-Pierre Wolf ,  Beat Michael Aebli ,  Gebhard Hug

发明人： Jean-Pierre Wolf ,  Beat Michael Aebli ,  Gebhard Hug

IPC分类号： C07F953

CPC分类号： C09D11/101 ,  A61K6/0052 ,  A61K6/08 ,  B33Y70/00 ,  C07F9/28 ,  C07F9/5036 ,  C07F9/5337 ,  C07F9/6521 ,  C08F2/50 ,  C09D4/00 ,  G03F7/0045 ,  G03F7/029 ,  G03F7/0384 ,  G03F7/0388 ,  G03F7/0755 ,  Y10S430/124 ,  A61K6/083 ,  C08L33/08 ,  C08L33/10 ,  C08L33/20 ,  C08L33/26 ,  C08L27/00 ,  C08L31/04 ,  C08L25/06 ,  C08L27/04 ,  C08L39/06 ,  A61K6/09 ,  C08L75/04 ,  A61K6/087 ,  C08L67/00 ,  C08L71/02 ,  A61K6/097 ,  C08L1/08

摘要： Compounds of the formula I R1 and R2 independently of one another are C1-C20alkyl, OR11, CF3 or halogen; R3, R4 and R5 independently of one another are hydrogen, C1-C20alkyl, OR1 or halogen; R6, R7, R8, R9 and R10 independently of one another are hydrogen, C1-C20alkyl; C2-C20alkyl which is interrupted once or more than once by nonconsecutive O atoms and which is unsubstituted or substituted by OH and/or SH; or R6, R7, R8, R9 and R10 are OR11, SR11, N(R12)(R13), phenyl or halogen; R11 is C1-C20alkyl, C3-C8cycloalkyl, phenyl, benzyl or C2-C20alkyl which is interrupted once or more than once by O or S and which is unsubstituted or substituted by OH and/or SH; R12 and R13 independently of one another are hydrogen, C1-C20alkyl, C3-C8cycloalkyl, phenyl, benzyl or C2-C20alkyl which is interrupted once or more than once by nonconsecutive O atoms and which is unsubstituted or substituted by OH and/or SH; or R12 and R13 together are C3-C5alkylene which can be interrupted by O, S or NR14; R14 is hydrogen, phenyl, C1-C12alkyl or C2-C12alkyl which is interrupted once or more than once by O or S and which is unsubstituted or substituted by OH and/or SH; and M is hydrogen, Li, Na or K; are valuable intermediates for the preparation of unsymmetrical bisacylphosphine oxides and monoacylphosphine oxides.

摘要翻译： 式IR1和R2的化合物彼此独立地为C1-C20烷基，OR11，CF3或卤素; R 3，R 4和R 5彼此独立地是氢，C 1 -C 20烷基，OR 1或卤素; R 6，R 7，R 8，R 9和R 10彼此独立地是氢，C 1 -C 20烷基; 被不连续的O原子中断一次或多于一次且未被取代或被OH和/或SH取代的C 2 -C 20烷基; 或R 6，R 7，R 8，R 9和R 10为OR 11，SR 11，N（R 12）（R 13），苯基或卤素; R 11是被O或S间隔一次或多于一次并且未被取代或被OH和/或SH取代的C 1 -C 20烷基，C 3 -C 8环烷基，苯基，苄基或C 2 -C 20烷基。 R 12和R 13彼此独立地是氢，C 1 -C 20烷基，C 3 -C 8环烷基，苯基，苄基或C 2 -C 20烷基，其被非连续的O原子中断一次或多于一次，并且是未取代的或被OH和/或SH取代; 或R 12和R 13一起是可被O，S或NR14中断的C 3 -C 5亚烷基; R 14是氢，苯基，C 1 -C 12烷基或C 2 -C 12烷基，其被O或S间隔一次或多于一次，并且是未取代的或被OH和/或SH取代; M为氢，Li，Na或K; 是制备不对称双酰基氧化膦和单酰基氧化膦的有价值的中间体。