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    Intralumenal stent device for use in body lumens of various diameters
    2.
    发明授权
    Intralumenal stent device for use in body lumens of various diameters 有权
    用于各种直径的体腔内的管腔内支架装置

    公开(公告)号：US07316711B2

    公开(公告)日：2008-01-08

    申请号：US10694723

    申请日：2003-10-29

    申请人： Jeffrey Allen ,  Mark Dolan ,  Richard Thomas

    发明人： Jeffrey Allen ,  Mark Dolan ,  Richard Thomas

    IPC分类号： A61F2/06

    CPC分类号： A61F2/915 ,  A61F2/91 ,  A61F2002/91508 ,  A61F2002/91541 ,  A61F2002/9155 ,  A61F2002/91558 ,  A61F2220/005 ,  A61F2220/0058 ,  A61F2230/0054

    摘要： The present invention is an intralumenal stent device made up of two or more elements. Each element has undulations forming peaks and valleys and is formed from a repeating series including a long segment, a first midsized segment, a short segment, and a second midsized segment. These elements are aligned on a common axis and are connected directly to an adjacent element by a connection. The stent incorporates the advantages of having both long and short segments into a single element.

    摘要翻译： 本发明是由两个或更多个元件构成的管腔内支架装置。 每个元件具有形成峰和谷的起伏，并且由包括长段，第一中心段，短段和第二中心段的重复序列形成。 这些元件在公共轴线上对准，并通过连接直接连接到相邻元件。 该支架具有将长片段和短片段都组合成单个元件的优点。

    Stented Valve Having Dull Struts
    4.
    发明申请
    Stented Valve Having Dull Struts 审中-公开
    具有钝的支柱的排气阀

    公开(公告)号：US20070239269A1

    公开(公告)日：2007-10-11

    申请号：US11278984

    申请日：2006-04-07

    申请人： Mark Dolan ,  Jeffrey Allen

    发明人： Mark Dolan ,  Jeffrey Allen

    IPC分类号： A61F2/24 ,  A61F2/84

    CPC分类号： A61F2/2412 ,  A61F2/2418 ,  A61F2/2475 ,  A61F2250/006

    摘要： A system for replacing a pulmonary valve includes a conduit having a lumen, a delivery catheter and a replacement valve device disposed on the delivery catheter. The replacement valve device includes a prosthetic valve connected to a valve support region of an expandable support structure. The valve support region includes a plurality of protective struts disposed between a first stent region and a second stent region. A method for replacing a pulmonary valve includes implanting a conduit and delivering a replacement valve device to the conduit. The replacement valve device includes a valve connected to a valve support region that includes a plurality of protective struts. The method also includes deploying the prosthetic valve device from a delivery catheter into the lumen, positioning the prosthetic valve device within the conduit lumen and expanding the prosthetic valve device into contact with the inner wall of the conduit.

    摘要翻译： 用于替换肺动脉瓣的系统包括具有内腔，输送导管和设置在输送导管上的置换瓣膜装置的导管。 替换阀装置包括连接到可扩张支撑结构的阀支撑区域的假体阀。 阀支撑区域包括设置在第一支架区域和第二支架区域之间的多个保护支柱。 用于替换肺动脉瓣膜的方法包括植入导管并将更换瓣膜装置输送到导管。 更换阀装置包括连接到包括多个保护支柱的阀支撑区域的阀。 该方法还包括将假体瓣膜装置从输送导管部署到内腔中，将人工瓣膜装置定位在导管管腔内并使人工瓣膜装置膨胀成与导管的内壁接触。

    Prosthetic valve delivery system
    5.
    发明授权
    Prosthetic valve delivery system 有权
    假体瓣膜输送系统

    公开(公告)号：US08021420B2

    公开(公告)日：2011-09-20

    申请号：US12403114

    申请日：2009-03-12

    申请人： Mark Dolan

    发明人： Mark Dolan

    IPC分类号： A61F2/24

    CPC分类号： A61M25/1011 ,  A61F2/2418 ,  A61F2/2433 ,  A61F2/2436 ,  A61F2250/0048 ,  A61M29/02 ,  A61M2025/0039 ,  A61M2025/004

    摘要： A prosthetic valve delivery system for percutaneously delivering and deploying a prosthetic valve within an existing valve is disclosed. The delivery system includes a stented prosthetic valve having a balloon-expandable stent portion with a prosthetic valve disposed therein and at least one self-expanding stent portion. The delivery system further includes a dual balloon catheter having a first balloon on which the stented prosthetic valve is disposed during delivery and a second balloon. Upon delivery within the existing valve, the self-expanding stent portion contacts the existing valve and the first balloon expands the balloon-expandable stent portion to a first diameter such that the stented prosthetic valve is in a first stage deployment configuration. The second balloon then expands the balloon-expandable stent portion to a second diameter, greater than the first diameter, such that the stented prosthetic valve is in a second stage deployment configuration being fully deployed within the existing valve.

    摘要翻译： 公开了一种用于在现有阀内经皮递送和展开假体瓣膜的假体瓣膜输送系统。 输送系统包括支架假体瓣膜，其具有球囊扩张支架部分，其中设置有人工瓣膜和至少一个自扩张支架部分。 输送系统还包括具有第一气囊的双气囊导管，其中支架假体瓣膜在输送期间设置在其上并具有第二气囊。 在现有阀门内传送后，自膨胀支架部分接触现有阀门，第一气囊将球囊扩张支架部分扩张至第一直径，使得支架假体瓣膜处于第一阶段展开构型。 然后，第二气囊将球囊扩张支架部分扩大到大于第一直径的第二直径，使得支架假体瓣膜处于完全展开在现有瓣膜内的第二阶段展开构型。

    Radially crush-resistant stent
    7.
    发明申请
    Radially crush-resistant stent 审中-公开
    径向抗压支架

    公开(公告)号：US20050203605A1

    公开(公告)日：2005-09-15

    申请号：US11079956

    申请日：2005-03-15

    申请人： Mark Dolan

    发明人： Mark Dolan

    IPC分类号： A61F2/00 ,  A61F2/06 ,  A61F2/24 ,  A61F2/84 ,  A61F2/90

    CPC分类号： A61F2/2418 ,  A61F2/91 ,  A61F2/915 ,  A61F2/958 ,  A61F2002/91525 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2230/0054 ,  A61F2250/0018

    摘要： A system for treating a vascular condition includes a catheter and a stent coupled to the catheter. The stent includes a stent framework having at least one stent segment with a plurality of interconnected struts and crowns and at least one stiffening ring having a plurality of ring segments connected between circumferentially adjacent crowns of the stent segment. The stiffening ring is oriented circumferentially about a longitudinal axis of the stent framework when the stent is deployed. A stent and a method of treating a vascular condition are also disclosed.

    摘要翻译： 用于治疗血管病症的系统包括与导管联接的导管和支架。 所述支架包括支架框架，所述支架框架具有至少一个具有多个互连的支柱和冠部的支架段和至少一个加强环，所述至少一个加强环具有连接在所述支架段的周向相邻冠部之间的多个环段。 当支架展开时，加强环围绕支架框架的纵向轴向定向。 还公开了支架和治疗血管病症的方法。

    Releasable polymer on drug elution stent and method
    8.
    发明授权
    Releasable polymer on drug elution stent and method 有权
    药物洗脱支架上的可释放聚合物和方法

    公开(公告)号：US08303639B2

    公开(公告)日：2012-11-06

    申请号：US11689733

    申请日：2007-03-22

    申请人： Mark Dolan ,  Matthew J. Birdsall ,  Eugene Tedeschi ,  Joseph Berglund ,  Raffy Brown

    发明人： Mark Dolan ,  Matthew J. Birdsall ,  Eugene Tedeschi ,  Joseph Berglund ,  Raffy Brown

    IPC分类号： A61F2/06

    CPC分类号： A61F2/958 ,  A61F2/91 ,  A61F2250/0067

    摘要： A method for treating a vascular condition is disclosed, the method comprising delivering a stent to a target region of a vessel, the stent including a drug polymer coating including an elution portion and a remaining portion, eluting the elution portion from the delivered stent for an elution period, heating the delivered stent after the elution period; and removing the remaining portion based on the heating.

    摘要翻译： 公开了一种用于治疗血管病症的方法，所述方法包括将支架输送到血管的靶区域，所述支架包括药物聚合物涂层，其包括洗脱部分和剩余部分，从所述输送的支架洗脱洗脱部分， 洗脱期后，在洗脱期后加热输送的支架; 并且基于加热去除剩余部分。

    Stent Having Spiral Channel for Drug Delivery
    9.
    发明申请
    Stent Having Spiral Channel for Drug Delivery 有权
    支架用于药物输送的螺旋通道

    公开(公告)号：US20090132031A1

    公开(公告)日：2009-05-21

    申请号：US11941591

    申请日：2007-11-16

    申请人： Brian Cook ,  Mark Dolan

    发明人： Brian Cook ,  Mark Dolan

    IPC分类号： A61F2/82

    CPC分类号： A61F2/88 ,  A61F2/86 ,  A61F2250/0035 ,  A61F2250/0068

    摘要： A drug delivery stent is formed by a metallic or polymeric tubular strut which is shaped into a generally cylindrical configuration, the tubular strut having a central lumen for containing a therapeutic substance or drug therein. The tubular strut has a continuous channel extending from the inside surface of the strut to the outside surface of the strut positioned spirally about or in a corkscrew fashion around a circumference of the tubular strut for delivering the therapeutic substance or drug to a stenotic lesion. The spiral or corkscrew channel width may be varied along the length of the strut to control elution rate and/or flexibility of the stent. The pitch of the spiral or corkscrew channel may also be varied along the length of the strut to control flexibility of the stent. The stent may be carried on a balloon of a balloon catheter to a site of a stenotic lesion where the stent is implanted.

    摘要翻译： 药物递送支架由金属或聚合物管状支柱形成，其形状为大致圆柱形的构造，管状支柱具有用于在其中容纳治疗物质或药物的中心腔。 管状支柱具有从支柱的内表面延伸到支柱的外表面的连续通道，所述支柱的外表面围绕螺旋状围绕或以开瓶器方式围绕管状支柱的圆周定位，用于将治疗物质或药物输送至狭窄病变。 螺旋或螺旋状通道宽度可以沿着支柱的长度变化以控制支架的洗脱速率和/或柔性。 螺旋或螺旋状通道的螺距也可以沿着支柱的长度变化以控制支架的柔性。 支架可以携带在球囊导管的球囊上，以移植支架的狭窄病变部位。

    Releasable Polymer on Drug Elution Stent and Method
    10.
    发明申请
    Releasable Polymer on Drug Elution Stent and Method 有权
    可释放聚合物对药物洗脱支架和方法的影响

    公开(公告)号：US20080234808A1

    公开(公告)日：2008-09-25

    申请号：US11689733

    申请日：2007-03-22

    申请人： Mark Dolan ,  Matthew J. Birdsall ,  Eugene Tedeschi ,  Joseph Berglund ,  Raffy Brown

    发明人： Mark Dolan ,  Matthew J. Birdsall ,  Eugene Tedeschi ,  Joseph Berglund ,  Raffy Brown

    IPC分类号： A61F2/06

    CPC分类号： A61F2/958 ,  A61F2/91 ,  A61F2250/0067

    摘要： A method for treating a vascular condition is disclosed, the method comprising delivering a stent to a target region of a vessel, the stent including a drug polymer coating including an elution portion and a remaining portion, eluting the elution portion from the delivered stent for an elution period, heating the delivered stent after the elution period; and removing the remaining portion based on the heating.

    摘要翻译： 公开了一种用于治疗血管病症的方法，所述方法包括将支架输送到血管的靶区域，所述支架包括药物聚合物涂层，其包括洗脱部分和剩余部分，从所述输送的支架洗脱洗脱部分， 洗脱期后，在洗脱期后加热输送的支架; 并且基于加热去除剩余部分。