公开(公告)号：US09012477B2

公开(公告)日：2015-04-21

申请号：US12652502

申请日：2010-01-05

申请人： Jie Zhang ,  Robert Lippert

发明人： Jie Zhang ,  Robert Lippert

IPC分类号： A61K31/445 ,  A61K31/245 ,  A61P23/02 ,  A61K31/24 ,  A61K9/70 ,  A61K31/167 ,  A61K47/32

CPC分类号： A61K31/24 ,  A61K9/7015 ,  A61K31/167 ,  A61K47/32 ,  A61K2300/00

摘要： A method for treating subjects experiencing neuropathic pain is provided. The method involves the application of a solid-forming local anesthetic formulation to a skin surface of the subject experiencing the neuropathic pain and then maintaining the formulation on the skin surface for a period of time sufficient to allow itself to transdermally deliver the local anesthetic to the subject thereby providing relief from the neuropathic pain within about 45 minutes.

摘要翻译： 提供了治疗经历神经性疼痛的受试者的方法。 该方法涉及将固体形成局部麻醉剂制剂施用于经历神经性疼痛的受试者的皮肤表面，然后将制剂保持在皮肤表面上足以允许其自身将局部麻醉剂递送至 从而在约45分钟内提供神经性疼痛的缓解。

公开(公告)号：US09186334B2

公开(公告)日：2015-11-17

申请号：US13049650

申请日：2011-03-16

申请人： Jie Zhang ,  Robert Lippert

发明人： Jie Zhang ,  Robert Lippert

IPC分类号： A61K31/24 ,  A61K9/70 ,  A61F7/02 ,  A61F7/03 ,  A61K31/167 ,  A61K31/245 ,  A61F7/00

CPC分类号： A61K9/7023 ,  A61F7/02 ,  A61F7/034 ,  A61F2007/0071 ,  A61F2007/0226 ,  A61F2007/0257 ,  A61F2007/0261 ,  A61F2007/0292 ,  A61K31/167 ,  A61K31/245 ,  A61K2300/00

摘要： The present disclosure is drawn to methods for treating various types of pain, including pain associated nerve entrapment, neuroma, headaches, connective tissue, arthritis, injury, and/or overuse. Specifically, the method includes the application of an analgesic system to a skin surface of a subject experiencing the pain and maintaining the analgesic system on the skin surface for an application period of at least 30 minutes. Following the application period the analgesic system can be removed and the subject being treated continues to experience reduction of pain for a period of 2 to 10, or even 4 to 12 hours after removal of the analgesic system. The analgesic system applied to the skin surface can include a heating component and a local anesthetic formulation.

摘要翻译： 本公开涉及用于治疗各种疼痛的方法，包括疼痛相关的神经阻滞，神经瘤，头痛，结缔组织，关节炎，损伤和/或过度使用。 具体地，该方法包括将镇痛系统应用于经历疼痛的受试者的皮肤表面，并将止痛系统保持在皮肤表面上至少30分钟的施用期。 在施用期后，可以除去止痛系统，并且除去止痛系统后，待治疗的受试者继续经历2至10次，甚至4至12小时的疼痛减轻。 应用于皮肤表面的止痛系统可以包括加热组分和局部麻醉剂制剂。

公开(公告)号：US09186273B2

公开(公告)日：2015-11-17

申请号：US12773239

申请日：2010-05-04

申请人： Jie Zhang ,  Robert Lippert

发明人： Jie Zhang ,  Robert Lippert

IPC分类号： A61K31/24 ,  A61F7/02 ,  A61K9/70 ,  A61K31/167 ,  A61K31/245 ,  A61K31/445 ,  A61F7/03 ,  A61F7/00

CPC分类号： A61F7/02 ,  A61F7/03 ,  A61F7/034 ,  A61F2007/0071 ,  A61F2007/0261 ,  A61F2007/0292 ,  A61K9/7023 ,  A61K31/167 ,  A61K31/245 ,  A61K31/445

摘要： The present disclosure is drawn to methods for treating various types of pain. Specifically, a method for treating various types of pain includes the application of an analgesic system to a skin surface of a subject experiencing the pain and maintaining the analgesic system on the skin surface for a period of time of at least 30 minutes. The analgesic system applied to the skin surface can include a heating component and a local anesthetic formulation which includes at least one local anesthetic. The heating component can be capable of heating the skin surface to a temperature of 36° C. to 42° C.

摘要翻译： 本公开涉及用于治疗各种类型的疼痛的方法。 具体地说，用于治疗各种疼痛的方法包括将镇痛系统施用于经历疼痛的受试者的皮肤表面，并将止痛系统保持在皮肤表面上至少30分钟的时间。 应用于皮肤表面的镇痛系统可以包括加热组分和包括至少一种局部麻醉剂的局部麻醉剂制剂。 加热部件能够将皮肤表面加热至36℃至42℃的温度。

公开(公告)号：US20120065259A1

公开(公告)日：2012-03-15

申请号：US13049650

申请日：2011-03-16

申请人： Jie Zhang ,  Robert Lippert

发明人： Jie Zhang ,  Robert Lippert

IPC分类号： A61K31/245 ,  A61P23/02 ,  A61P25/00

CPC分类号： A61K9/7023 ,  A61F7/02 ,  A61F7/034 ,  A61F2007/0071 ,  A61F2007/0226 ,  A61F2007/0257 ,  A61F2007/0261 ,  A61F2007/0292 ,  A61K31/167 ,  A61K31/245 ,  A61K2300/00

摘要： The present disclosure is drawn to methods for treating various types of pain, including pain associated nerve entrapment, neuroma, headaches, connective tissue, arthritis, injury, and/or overuse. Specifically, the method includes the application of an analgesic system to a skin surface of a subject experiencing the pain and maintaining the analgesic system on the skin surface for an application period of at least 30 minutes. Following the application period the analgesic system can be removed and the subject being treated continues to experience reduction of pain for a period of 2 to 10, or even 4 to 12 hours after removal of the analgesic system. The analgesic system applied to the skin surface can include a heating component and a local anesthetic formulation.

摘要翻译： 本公开涉及用于治疗各种疼痛的方法，包括疼痛相关的神经阻滞，神经瘤，头痛，结缔组织，关节炎，损伤和/或过度使用。 具体地，该方法包括将镇痛系统应用于经历疼痛的受试者的皮肤表面，并将止痛系统保持在皮肤表面上至少30分钟的施用期。 在施用期后，可以除去止痛系统，并且除去止痛系统后，待治疗的受试者继续经历2至10次，甚至4至12小时的疼痛减轻。 应用于皮肤表面的止痛系统可以包括加热组分和局部麻醉剂制剂。

公开(公告)号：US20110112189A1

公开(公告)日：2011-05-12

申请号：US12773239

申请日：2010-05-04

申请人： Jie Zhang ,  Robert Lippert

发明人： Jie Zhang ,  Robert Lippert

IPC分类号： A61K31/245 ,  A61P23/02 ,  A61P25/02 ,  A61P19/02

CPC分类号： A61F7/02 ,  A61F7/03 ,  A61F7/034 ,  A61F2007/0071 ,  A61F2007/0261 ,  A61F2007/0292 ,  A61K9/7023 ,  A61K31/167 ,  A61K31/245 ,  A61K31/445

摘要： The present disclosure is drawn to methods for treating nerve entrapment pain; neuroma pain; headache associated with neuralgia; connective tissue pain such as iliotibial band pain, blood vessel pain, tendinopathy pain, medial tibial stress syndrome pain, bursitis, etc.; arthritis pain such as osteoarthritis pain or rheumatoid arthritis pain; pain associated with injury such as fracture, severance, break, sprain, strain, tear, point pain, (e.g., trigger point pain or hit point pain), focal pain, or bruise; or combinations of these pains. Specifically, a method for treating various types of pain includes the application of an analgesic system to a skin surface of a subject experiencing the pain and maintaining the analgesic system on the skin surface for a period of time of at least 30 minutes. The analgesic system applied to the skin surface can include a heating component and a local anesthetic formulation which includes at least one local anesthetic. The heating component can be capable of heating the skin surface to a temperature of 36° C. to 42° C.

摘要翻译： 本公开涉及治疗神经夹带痛的方法; 神经痛; 头痛与神经痛有关; 结缔组织疼痛如髂胫带疼痛，血管痛，腱鞘疼痛，胫骨内侧应力综合征疼痛，滑囊炎等; 关节炎疼痛如骨关节炎疼痛或类风湿性关节炎疼痛; 与损伤相关的疼痛，如骨折，分离，断裂，扭伤，应变，撕裂，点疼痛（例如触发点疼痛或命中痛），局灶性疼痛或瘀伤; 或这些疼痛的组合。 具体地说，用于治疗各种疼痛的方法包括将镇痛系统施用于遭受疼痛的受试者的皮肤表面，并将止痛系统保持在皮肤表面上至少30分钟的时间。 应用于皮肤表面的镇痛系统可以包括加热组分和包括至少一种局部麻醉剂的局部麻醉剂制剂。 加热部件能够将皮肤表面加热至36℃至42℃的温度。

公开(公告)号：US20110015229A1

公开(公告)日：2011-01-20

申请号：US12652502

申请日：2010-01-05

申请人： Jie Zhang ,  Robert Lippert

发明人： Jie Zhang ,  Robert Lippert

IPC分类号： A61K31/445 ,  A61K31/245 ,  A61K31/167 ,  A61P23/02 ,  A61P29/00

CPC分类号： A61K31/24 ,  A61K9/7015 ,  A61K31/167 ,  A61K47/32 ,  A61K2300/00

摘要： A method for treating subjects experiencing neuropathic pain is provided. The method involves the application of a solid-forming local anesthetic formulation to a skin surface of the subject experiencing the neuropathic pain and then maintaining the formulation on the skin surface for a period of time sufficient to allow itself to transdermally deliver the local anesthetic to the subject thereby providing relief from the neuropathic pain within about 45 minutes.

摘要翻译： 提供了治疗经历神经性疼痛的受试者的方法。 该方法涉及将固体形成局部麻醉剂制剂施用于经历神经性疼痛的受试者的皮肤表面，然后将制剂保持在皮肤表面上足以允许其自身将局部麻醉剂递送至 从而在约45分钟内提供神经性疼痛的缓解。

公开(公告)号：USD1041229S1

公开(公告)日：2024-09-10

申请号：US29832192

申请日：2022-03-25

申请人： Jie Zhang

设计人： Jie Zhang

摘要： FIG. 1 is a perspective view of a heating stove, showing my new design;
FIG. 2 is another perspective view thereof;
FIG. 3 is a front view thereof;
FIG. 4 is a rear view thereof;
FIG. 5 is a left side view thereof;
FIG. 6 is a right side view thereof;
FIG. 7 is a top plan view thereof;
FIG. 8 is a bottom plan view thereof;
FIG. 9 is an enlarged view of portion of FIG. 1; and,
FIG. 10 is another enlarged view of portion of FIG. 1.
The dash-dash broken lines show portions of the heating stove and form no part of the claimed design. The dot-dash broken lines shown in FIGS. 1, 9 & 10 define the boundary of the enlargement area and form no part of the claimed design.

公开(公告)号：US20160345828A1

公开(公告)日：2016-12-01

申请号：US15158803

申请日：2016-05-19

申请人： Qiang Yang ,  Jie Zhang

发明人： Qiang Yang ,  Jie Zhang

IPC分类号： A61B3/15 ,  G02B26/10 ,  A61B3/12 ,  A61B3/113 ,  A61B3/00

CPC分类号： A61B3/152 ,  A61B3/0025 ,  A61B3/113 ,  A61B3/1225 ,  G02B26/105

摘要： A system for multi-scale closed-loop eye tracking to compensate for translation and rotation motion while imaging in vivo a surface area of an internal structure of an eye of a subject includes a narrow field imaging device optically coupled to an optical path to receive light reflected from the surface area of the structure of the eye. A wide field camera is optically coupled to the optical path by a beam splitter disposed in the optical path. A tracking mirror is disposed in the optical path between the beam splitter and the structure of the eye. A control process algorithm actively compensates substantially in real time for both translational and rotational movements of the eye. A system where a torsional correction device causes a rotating movement of a subject's head and a method for multi-scale closed-loop eye tracking are also described.

摘要翻译： 一种用于多尺度闭环眼睛跟踪的系统，用于补偿平移和旋转运动，同时在体内成像对象的眼睛的内部结构的表面区域包括光学耦合到光路以接收光的窄场成像装置 从眼睛结构的表面积反射出来。 通过设置在光路中的分束器将宽视场摄像机光耦合到光路。 跟踪镜设置在分束器和眼睛结构之间的光路中。 控制过程算法主动地实时补偿眼睛的平移和旋转运动。 还描述了一种系统，其中扭转校正装置引起受试者的头部的旋转运动以及用于多尺度闭环眼睛跟踪的方法。

公开(公告)号：US09346245B2

公开(公告)日：2016-05-24

申请号：US13083161

申请日：2011-04-08

申请人： Chengdong Wu ,  Jie Zhang

发明人： Chengdong Wu ,  Jie Zhang

IPC分类号： A47K13/14 ,  B32B21/02 ,  A47K13/02 ,  B32B27/30

CPC分类号： B32B21/02 ,  A47K13/02 ,  B32B27/308 ,  B32B2307/412 ,  B32B2317/12 ,  B32B2317/16 ,  B32B2333/12 ,  B32B2509/00 ,  Y10T428/24802

摘要： Embodiments of the present disclosure include a laminate composite toilet lid and seat and a method of manufacturing thereof. The toilet lid includes a core structural layer having a shape and size associated with the toilet lid. The toilet lid also includes a first decorative graphic layer disposed on a first surface of the core structural layer. The toilet lid further includes a plurality of exterior layers disposed on exterior surfaces of the core structural layer and the first decorative graphic layer, the exterior layers configured to envelop the toilet lid.

摘要翻译： 本公开的实施例包括层压复合马桶盖和座椅及其制造方法。 马桶盖包括具有与马桶盖相关联的形状和尺寸的芯结构层。 马桶盖还包括设置在芯结构层的第一表面上的第一装饰图形层。 马桶盖还包括设置在芯结构层和第一装饰图形层的外表面上的多个外层，外层构造成包封马桶盖。

公开(公告)号：US09205180B2

公开(公告)日：2015-12-08

申请号：US13522819

申请日：2011-01-19

申请人： Jie Zhang ,  Bo Yi ,  Changsheng Wu ,  Zhirong Tang ,  Qiyi Luo

发明人： Jie Zhang ,  Bo Yi ,  Changsheng Wu ,  Zhirong Tang ,  Qiyi Luo

IPC分类号： A61L33/00 ,  A61L31/06 ,  A61L31/16 ,  A61F2/91

CPC分类号： A61F2/82 ,  A61F2/91 ,  A61F2240/001 ,  A61F2250/0068 ,  A61L31/06 ,  A61L31/16 ,  A61L2300/416 ,  B05C21/00 ,  C08L67/04

摘要： A method and a device for loading a medical appliance with a medicament and/or polymer includes capturing images of a plurality of grooves or holes of the medical appliance using an image capturing device; performing digital image processing on the image of each of the grooves or holes to obtain a pattern of each of the grooves or holes; calculating a central position of the pattern of each of the grooves or holes, and determining a loading position of each of the grooves or holes based on the central position; and adjusting a relative position between a loading device and the medical appliance to align an outlet of the loading device with the loading position of the medical appliance, and loading each of the grooves or holes with the medicament and/or polymer. The method and device can load the medical appliance with the medicament and/or polymer fast and efficiently.

摘要翻译： 一种用于装载具有药物和/或聚合物的医疗器具的方法和装置包括使用图像捕获装置捕获医疗器具的多个凹槽或孔的图像; 对每个凹槽或孔的图像执行数字图像处理以获得每个凹槽或孔的图案; 计算每个凹槽或孔的图案的中心位置，以及基于中心位置确定每个凹槽或孔的装载位置; 以及调整加载装置和医疗器具之间的相对位置，以将装载装置的出口与医疗器具的装载位置对齐，并且用药物和/或聚合物装载每个凹槽或孔。 该方法和装置可以快速且有效地加载具有药物和/或聚合物的医疗器具。