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    Cardiac activation sequence monitoring for ischemia detection
    2.
    发明授权
    Cardiac activation sequence monitoring for ischemia detection 失效
    心脏激活序列监测缺血检测

    公开(公告)号：US08626276B2

    公开(公告)日：2014-01-07

    申请号：US12847657

    申请日：2010-07-30

    申请人： Yi Zhang ,  Scott A. Meyer ,  Jeffrey E. Stahmann ,  Carlos Alberto Ricci ,  Marina Brockway ,  Aaron R. McCabe ,  Yinghong Yu ,  Donald L. Hopper

    发明人： Yi Zhang ,  Scott A. Meyer ,  Jeffrey E. Stahmann ,  Carlos Alberto Ricci ,  Marina Brockway ,  Aaron R. McCabe ,  Yinghong Yu ,  Donald L. Hopper

    IPC分类号： A61B5/04

    CPC分类号： A61N1/3702 ,  A61B5/0452 ,  A61B5/7203

    摘要： Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed to detect, monitor, track and/or trend ischemia using cardiac activation sequence information. Ischemia detection may involve sensing composite cardiac signals using implantable electrodes, and performing a signal separation that produces one or more cardiac activation signal vectors associated with one or more cardiac activation sequences. A change in the signal vector may be detected using subsequent separations. The change may be an elevation or depression of the ST segment of a cardiac cycle or other change indicative of myocardial ischemia, myocardial infarction, or other pathological change. The change may be used to predict, quantify, and/or qualify an event such as an arrhythmia, a myocardial infarction, or other pathologic change. Information associated with the vectors may be stored and used to track the vectors.

    摘要翻译： 提供一种或多种监测，诊断，除颤和起搏的心脏监测和/或刺激方法和系统。 使用心脏信号分离来使用心脏激活序列信息来检测，监测，跟踪和/或趋势性缺血。 缺血检测可以涉及使用可植入电极感测复合心脏信号，并且执行产生与一个或多个心脏激活序列相关联的一个或多个心脏激活信号载体的信号分离。 可以使用后续分离来检测信号矢量的变化。 该变化可以是心​​脏周期的ST段的升高或抑制或指示心肌缺血，心肌梗死或其他病理变化的其它变化。 该变化可用于预测，量化和/或限定诸如心律失常，心肌梗死或其它病理变化的事件。 与矢量相关联的信息可以被存储并用于跟踪矢量。

    Cardiac Activation Sequence Monitoring for Ischemia Detection
    3.
    发明申请
    Cardiac Activation Sequence Monitoring for Ischemia Detection 失效
    缺血检测心脏激活序列监测

    公开(公告)号：US20100298729A1

    公开(公告)日：2010-11-25

    申请号：US12847657

    申请日：2010-07-30

    申请人： Yi Zhang ,  Scott A. Meyer ,  Jeffrey E. Stahmann ,  Carlos Alberto Ricci ,  Marina Brockway ,  Aaron R. McCabe ,  Yinghong Yu ,  Donald L. Hopper

    发明人： Yi Zhang ,  Scott A. Meyer ,  Jeffrey E. Stahmann ,  Carlos Alberto Ricci ,  Marina Brockway ,  Aaron R. McCabe ,  Yinghong Yu ,  Donald L. Hopper

    IPC分类号： A61B5/0452

    CPC分类号： A61N1/3702 ,  A61B5/0452 ,  A61B5/7203

    摘要： Cardiac monitoring and/or stimulation methods and systems that provide one or more of monitoring, diagnosing, defibrillation, and pacing. Cardiac signal separation is employed to detect, monitor, track and/or trend ischemia using cardiac activation sequence information. Ischemia detection may involve sensing composite cardiac signals using implantable electrodes, and performing a signal separation that produces one or more cardiac activation signal vectors associated with one or more cardiac activation sequences. A change in the signal vector may be detected using subsequent separations. The change may be an elevation or depression of the ST segment of a cardiac cycle or other change indicative of myocardial ischemia, myocardial infarction, or other pathological change. The change may be used to predict, quantify, and/or qualify an event such as an arrhythmia, a myocardial infarction, or other pathologic change. Information associated with the vectors may be stored and used to track the vectors.

    摘要翻译： 提供一种或多种监测，诊断，除颤和起搏的心脏监测和/或刺激方法和系统。 使用心脏信号分离来使用心脏激活序列信息来检测，监测，跟踪和/或趋势性缺血。 缺血检测可以涉及使用可植入电极感测复合心脏信号，并且执行产生与一个或多个心脏激活序列相关联的一个或多个心脏激活信号载体的信号分离。 可以使用后续分离来检测信号矢量的变化。 该变化可以是心​​脏周期的ST段的升高或抑制或指示心肌缺血，心肌梗死或其他病理变化的其它变化。 该变化可用于预测，量化和/或限定诸如心律失常，心肌梗死或其它病理变化的事件。 与矢量相关联的信息可以被存储并用于跟踪矢量。

    Management of fusion beat detection during capture threshold determination
    5.
    发明授权
    Management of fusion beat detection during capture threshold determination 有权
    捕获阈值确定期间融合搏动检测的管理

    公开(公告)号：US09020596B2

    公开(公告)日：2015-04-28

    申请号：US13546820

    申请日：2012-07-11

    申请人： Shibaji Shome ,  Yanting Dong ,  Aaron R. McCabe

    发明人： Shibaji Shome ,  Yanting Dong ,  Aaron R. McCabe

    IPC分类号： A61N1/37

    CPC分类号： A61N1/3712

    摘要： An improved technique is described for dealing with the detection of fusion beats when capture verification is performed by a cardiac pacing device such as during a capture threshold determination procedure. Schemes for classifying heart beats may misclassify beats as fusion beats due to feature/morphology changes in the test electrogram waveform that may occur even when capture is achieved.

    摘要翻译： 描述了一种改进的技术，用于处理在心脏起搏装置执行捕获验证时，例如在捕获阈值确定过程期间的融合节拍的检测。 分类心脏跳动的方案可能由于测试电描记图波形中的特征/形态变化而将节拍错误分类为融合节拍，即使实现捕获也可能发生。

    AUTOTHRESHOLD WITH SENSING FROM PACING CATHODE
    7.
    发明申请
    AUTOTHRESHOLD WITH SENSING FROM PACING CATHODE 有权
    自动检测从PACING CATHODE

    公开(公告)号：US20130138174A1

    公开(公告)日：2013-05-30

    申请号：US13684814

    申请日：2012-11-26

    申请人： David W. Yost ,  Deepa Mahajan ,  Clayton S. Foster ,  Aaron R. McCabe ,  Shibaji Shome ,  Amy Jean Brisben

    发明人： David W. Yost ,  Deepa Mahajan ,  Clayton S. Foster ,  Aaron R. McCabe ,  Shibaji Shome ,  Amy Jean Brisben

    IPC分类号： A61N1/37

    CPC分类号： A61N1/3712

    摘要： Cardiac electrostimulation energy is delivered to a heart chamber of a subject according to a normal pacing mode using a set of implantable pacing electrodes. When a threshold test for the heart chamber is initiated and a sensing electrode independent from the set of pacing electrodes is unavailable for the heart chamber, cardiac electrostimulation energy is delivered to the subject according to a threshold test mode. The threshold test mode includes sensing a cardiac activity signal from a subject using a set of sensing electrodes that includes an electrode common to the set of pacing electrodes, and changing the electrostimulation energy and sensing a resulting cardiac activity signal using the set of sensing electrodes to determine the optimum electrostimulation energy for capture of the heart chamber.

    摘要翻译： 心脏电刺激能量使用一组可植入起搏电极根据正常起搏模式递送到受试者的心室。 当启动心脏室的阈值测试并且独立于该组起搏电极的感测电极不能用于心脏室时，根据阈值测试模式将心脏电刺激能量递送给受试者。 阈值测试模式包括使用包括一组起搏电极的电极的一组感测电极来感测来自对象的心脏活动信号，并且使用该组感测电极改变电刺激能量并感测所得到的心脏活动信号， 确定用于捕获心室的最佳电刺激能量。

    WIRELESS ECG IN IMPLANTABLE DEVICES
    9.
    发明申请
    WIRELESS ECG IN IMPLANTABLE DEVICES 有权
    无线心电图在可植入的设备

    公开(公告)号：US20130046195A1

    公开(公告)日：2013-02-21

    申请号：US13657224

    申请日：2012-10-22

    申请人： Aaron R. McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas R. Daum ,  Yi Zhang

    发明人： Aaron R. McCabe ,  Avram Scheiner ,  Geng Zhang ,  Quan Ni ,  Douglas R. Daum ,  Yi Zhang

    IPC分类号： A61B5/0408

    CPC分类号： A61B5/0402 ,  A61N1/365 ,  A61N1/3756

    摘要： An implantable medical device such as an implantable pacemaker or implantable cardioverter/defibrillator includes a programmable sensing circuit providing for sensing of a signal approximating a surface electrocardiogram (ECG) through implanted electrodes. With various electrode configurations, signals approximating various standard surface ECG signals are acquired without the need for attaching electrodes with cables onto the skin. The various electrode configurations include, but are not limited to, various combinations of intracardiac pacing electrodes, portions of the implantable medical device contacting tissue, and electrodes incorporated onto the surface of the implantable medical device.

    摘要翻译： 诸如可植入起搏器或植入式心律转复/除颤器的可植入医疗装置包括可编程感测电路，用于通过植入电极感测接近表面心电图（ECG）的信号。 通过各种电极配置，获取近似各种标准表面ECG信号的信号，而不需要将电极与电缆连接在皮肤上。 各种电极配置包括但不限于心脏内起搏电极，可植入医疗器械接触组织的部分和结合到可植入医疗装置的表面上的电极的各种组合。

    SENSING VECTOR CONFIGURATION IN ICD TO ASSIST ARRHYTHMIA DETECTION AND ANNOTATION
    10.
    发明申请
    SENSING VECTOR CONFIGURATION IN ICD TO ASSIST ARRHYTHMIA DETECTION AND ANNOTATION 有权
    ICD中的感应矢量配置，以帮助ARRHYTHMIA检测和报告

    公开(公告)号：US20090306486A1

    公开(公告)日：2009-12-10

    申请号：US12478476

    申请日：2009-06-04

    申请人： Dan Li ,  Allan C. Shuros ,  Quan Ni ,  Aaron R. McCabe ,  Yunlong Zhang ,  Jaeho Kim

    发明人： Dan Li ,  Allan C. Shuros ,  Quan Ni ,  Aaron R. McCabe ,  Yunlong Zhang ,  Jaeho Kim

    IPC分类号： A61B5/046 ,  A61B5/02 ,  A61B5/0464

    CPC分类号： A61B5/0464 ,  A61B5/0215 ,  A61B5/0422 ,  A61B5/046 ,  A61N1/3622 ,  A61N1/3702

    摘要： An apparatus comprises an implantable cardiac signal sensing circuit, configured to provide a sensed near-field depolarization signal from a ventricle and to provide a sensed a far-field intrinsic atrial signal using a far-field atrial sensing channel, and a controller circuit communicatively coupled to the cardiac signal sensing circuit. The controller circuit includes a P-wave detection module configured to detect an atrial depolarization in the sensed far-field intrinsic atrial signal and a tachyarrhythmia detection module configured to detect an episode of tachyarrhythmia using the sensed near-field depolarization signal and to determine whether the tachyarrhythmia episode is indicative of supraventricular tachycardia (SVT) using the detected atrial depolarization and the sensed near-field depolarization signal.

    摘要翻译： 一种装置包括可植入心脏信号感测电路，其被配置为提供来自心室的感测的近场去极化信号，并且使用远场心房感测通道提供感测到的远场固有心房信号，以及控制器电路， 到心脏信号感测电路。 所述控制器电路包括P波检测模块，所述P波检测模块被配置为检测所感测的远场固有心房信号中的心房去极化，以及快速性心律失常检测模块，其被配置为使用所感测的近场去极化信号来检测快速性心律失常发作，并且确定是否 快速性心律失常发作指示使用检测到的心房去极化和感测的近场去极化信号的室上性心动过速（SVT）。