Abstract:
The present invention provides a kind of benzopyrone compounds having a structure of formula (I) and the pharmaceutically acceptable salts or prodrugs thereof, and the pharmaceutical compositions containing such compounds, which can be used to regulate the novel estrogen receptor ER-a36, and prevent and/or treat the related diseases mediated by the ER-a36 receptor, such as cancers, etc.
Abstract:
Provided herein in certain embodiments are compounds, pharmaceutical compositions and methods for modulating the functions of estrogen receptor alpha 36, for preventing and/or treating diseases related to estrogen receptor alpha 36, for preventing and/or treating respiratory diseases such as asthma, for inducing cell death and/or inhibiting cell proliferation and for preventing and/or treating diseases involving abnormal cell proliferation such as cancers.
Abstract:
Provided herein in certain embodiments are antibodies, antibody fragments, pharmaceutical compositions, methods for modulating the functions of estrogen receptor alpha 36, and methods for preventing and/or treating diseases mediated by estrogen receptor alpha 36.
Abstract:
Provided herein in certain embodiments are compounds, pharmaceutical compositions and methods for modulating the functions of estrogen receptor alpha 36, for preventing and/or treating diseases related to estrogen receptor alpha 36, for preventing and/or treating respiratory diseases such as asthma, for inducing cell death and/or inhibiting cell proliferation and for preventing and/or treating diseases involving abnormal cell proliferation such as cancers.
Abstract:
The present invention provides a kind of benzopyrone compounds having a structure of formula (I) and the pharmaceutically acceptable salts or prodrugs thereof, and the pharmaceutical compositions containing such compounds, which can be used to regulate the novel estrogen receptor ER-a36, and prevent and/or treat the related diseases mediated by the ER-a36 receptor, such as cancers, etc.
Abstract:
Provided herein in certain embodiments are compounds, pharmaceutical compositions and methods for modulating the functions of estrogen receptor alpha 36, for preventing and/or treating diseases mediated by estrogen receptor alpha 36, for preventing and/or treating osteoporosis, for inducing cell death and/or inhibiting cell proliferation and for preventing and/or treating diseases involving abnormal cell proliferation such as cancers.
Abstract:
A method of encoding video using intra prediction mode dependent quantization matrix includes: calculating an array of quantizers for each size of block unit (100); encoding the arrays of quantizers into header of compressed video stream (102); selecting one scanning order based on a selected intra prediction mode among a plurality of scanning orders (112); scanning the array of quantizers to obtain a block of quantizers based on the selected scanning order (114).
Abstract:
The subject disclosure is directed towards a data deduplication technology in which a hash index service's index and/or indexing operations are adaptable to balance deduplication performance savings, throughput and resource consumption. The indexing service may employ hierarchical chunking using different levels of granularity corresponding to chunk size, a sampled compact index table that contains compact signatures for less than all of the hash index's (or subspace's) hash values, and/or selective subspace indexing based on similarity of a subspace's data to another subspace's data and/or to incoming data chunks.
Abstract:
An image coding method includes obtaining image format information, determining a subsampling method for a luminance signal, storing the subsampling method in a memory, obtaining the subsampling method from the memory, performing subsampling on a luminance signal of a surrounding pixel, calculating a parameter of the linear model using (i) the luminance signal that is subsampled and (ii) chrominance of the surrounding pixel, performing subsampling on the luminance signal of the current block to be coded, and calculating prediction chrominance of the current block to be coded using (i) the parameter of the linear model and (ii) the luminance signal that is subsampled.