Synthesis of polyanhydrides
    3.
    发明授权
    Synthesis of polyanhydrides 有权
    聚酐的合成

    公开(公告)号:US07411031B2

    公开(公告)日:2008-08-12

    申请号:US10848560

    申请日:2004-05-18

    IPC分类号: C08G63/02 C07C61/00 C07C63/00

    摘要: The present invention provides a method for forming compounds of Formula HO—C(═O)R1—X—R2—X—R1—C(═O)—O—H wherein compound (I) can be polymerized to provide a polymer that contains therapeutically active compounds. In the compounds of the invention, each R1 is group that will provide the therapeutically active compound upon hydrolysis of the polymer; each X is independently an ester linkage or an amide linkage; and R2 is a linking group.

    摘要翻译: 本发明提供了一种形成式<β的化合物的方法,该方法包括在线式描述=“在线式”中的末端=“铅”→HO-C( - )R 1 - XR 2 -XR 1 -C(-O)-OH&lt;β-in-line-formula description =“In-line Formulas”end =“tail”?>其中 化合物(I)可以聚合以提供含有治疗活性化合物的聚合物。 在本发明的化合物中,每个R 1是在聚合物水解时提供治疗活性化合物的基团; 每个X独立地是酯键或酰胺键; R 2是连接基团。

    Synthesis of Polyanhydrides
    4.
    发明申请
    Synthesis of Polyanhydrides 审中-公开
    聚酐的合成

    公开(公告)号:US20080234235A1

    公开(公告)日:2008-09-25

    申请号:US12026925

    申请日:2008-02-06

    摘要: The present invention provides a method for forming compounds of Formula HO—C(═O)R1—X—R2—X—R1—C(═O)—O—H wherein compound (I) can be polymerized to provide a polymer that contains therapeutically active compounds. In the compounds of the invention, each R1 is group that will provide the therapeutically active compound upon hydrolysis of the polymer; each X is independently an ester linkage or an amide linkage; and R2 is a linking group.

    摘要翻译: 本发明提供了一种形成式<β的化合物的方法,该方法包括在线式描述=“在线式”中的末端=“铅”→HO-C( - )R 1 - XR 2 -XR 1 -C(-O)-OH&lt;β-in-line-formula description =“In-line Formulas”end =“tail”?>其中 化合物(I)可以聚合以提供含有治疗活性化合物的聚合物。 在本发明的化合物中,每个R 1是在聚合物水解时提供治疗活性化合物的基团; 每个X独立地是酯键或酰胺键; R 2是连接基团。