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公开(公告)号：US20090112291A1
公开(公告)日：2009-04-30
申请号：US12256811
申请日：2008-10-23
IPC分类号： A61N1/02
CPC分类号： A61N1/3787
摘要： A charging system for an implantable medical device having a secondary coil. The charging system includes an external power source having at least one primary coil, a modulation, circuit operatively coupled to the primary coil and capable of driving it in a manner characterized by a charging parameter, and a sensor in communication with the modulation circuit and capable of sensing a condition indicating a need to adjust the charging parameter during a charging process. The parameter may be varied so that data sensed by the sensor meets a threshold requirement, which may be based on a patient preference, a government regulation, a recommendation promulgated by a health authority and/or a requirement associated with another device carried by the patient. In one embodiment, the regulation dictates maximum magnetic field exposure, and a field limiting circuit is employed to adjust the charging process.
摘要翻译： 一种具有次级线圈的可植入医疗装置的充电系统。 充电系统包括外部电源，该外部电源具有至少一个初级线圈，可操作地耦合到初级线圈并且能够以特征在于充电参数的方式驱动它的调制电路，以及与调制电路通信并具有能力的传感器 感测在充电过程中指示需要调整充电参数的条件。 该参数可以变化，使得由传感器感测的数据满足阈值要求，其可以基于患者偏好，政府法规，卫生当局颁布的建议和/或与患者携带的另一装置相关联的要求 。 在一个实施例中，调节规定了最大磁场曝光，并且采用场限制电路来调节充电过程。
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公开(公告)号：US20080269841A1
公开(公告)日：2008-10-30
申请号：US11799108
申请日：2007-04-30
IPC分类号： A61N1/02
CPC分类号： G08C17/02 , A61B5/0002 , A61M5/172 , A61N1/08 , A61N1/37223 , A61N1/37252 , H03F3/393
摘要： This disclosure describes a chopper mixer telemetry circuit for use in a wireless receiver. The receiver may be located in an implantable medical device (IMD) or external programmer. The chopper mixer telemetry circuit may include a mixer amplifier that operates as a synchronous demodulator to provide selective extraction of wireless signals received from a transmitter while suppressing out-of-band noise that can undermine the reliability of the telemetry link between an IMD or programmer and another device. The mixer amplifier may utilize parallel signal paths to convert the received telemetry signal into an in-phase (I) signal component and a quadrature (Q) signal component and recombine the I and Q signal components to reconstruct the total signal independently of the phase mismatch between the transmitter and receiver. Each signal path may include a chopper-stabilized mixer amplifier that amplifies telemetry signals within a desired band while suppressing out-of-band noise.
摘要翻译： 本公开描述了一种用于无线接收机的斩波器混频器遥测电路。 接收器可以位于可植入医疗装置（IMD）或外部编程器中。 斩波混频器遥测电路可以包括混频器放大器，其作为同步解调器操作以提供从发射机接收的无线信号的选择性提取，同时抑制可能破坏IMD或编程器之间的遥测链路的可靠性的带外噪声， 另一个设备。 混频器放大器可以利用并行信号路径将接收到的遥测信号转换为同相（I）信号分量和正交（Q）信号分量，并重新组合I和Q信号分量，以独立于相位失配重建总信号 在发射机和接收机之间。 每个信号路径可以包括斩波稳定的混频器放大器，其在抑制带外噪声的同时放大期望频带内的遥测信号。
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公开(公告)号：US08781595B2
公开(公告)日：2014-07-15
申请号：US11799108
申请日：2007-04-30
CPC分类号： G08C17/02 , A61B5/0002 , A61M5/172 , A61N1/08 , A61N1/37223 , A61N1/37252 , H03F3/393
摘要： This disclosure describes a chopper mixer telemetry circuit for use in a wireless receiver. The receiver may be located in an implantable medical device (IMD) or external programmer. The chopper mixer telemetry circuit may include a mixer amplifier that operates as a synchronous demodulator to provide selective extraction of wireless signals received from a transmitter while suppressing out-of-band noise that can undermine the reliability of the telemetry link between an IMD or programmer and another device. The mixer amplifier may utilize parallel signal paths to convert the received telemetry signal into an in-phase (I) signal component and a quadrature (Q) signal component and recombine the I and Q signal components to reconstruct the total signal independently of the phase mismatch between the transmitter and receiver. Each signal path may include a chopper-stabilized mixer amplifier that amplifies telemetry signals within a desired band while suppressing out-of-band noise.
摘要翻译： 本公开描述了一种用于无线接收机的斩波器混频器遥测电路。 接收器可以位于可植入医疗装置（IMD）或外部编程器中。 斩波混频器遥测电路可以包括混频器放大器，其作为同步解调器操作以提供从发射机接收的无线信号的选择性提取，同时抑制可能破坏IMD或编程器之间的遥测链路的可靠性的带外噪声， 另一个设备。 混频器放大器可以利用并行信号路径将接收到的遥测信号转换为同相（I）信号分量和正交（Q）信号分量，并重新组合I和Q信号分量，以独立于相位失配重建总信号 在发射机和接收机之间。 每个信号路径可以包括斩波稳定的混频器放大器，其在抑制带外噪声的同时放大期望频带内的遥测信号。
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公开(公告)号：US08244367B2
公开(公告)日：2012-08-14
申请号：US12256811
申请日：2008-10-23
CPC分类号： A61N1/3787
摘要： A charging system for an implantable medical device having a secondary coil. The charging system includes an external power source having at least one primary coil, a modulation, circuit operatively coupled to the primary coil and capable of driving it in a manner characterized by a charging parameter, and a sensor in communication with the modulation circuit and capable of sensing a condition indicating a need to adjust the charging parameter during a charging process. The parameter may be varied so that data sensed by the sensor meets a threshold requirement, which may be based on a patient preference, a government regulation, a recommendation promulgated by a health authority and/or a requirement associated with another device carried by the patient. In one embodiment, the regulation dictates maximum magnetic field exposure, and a field limiting circuit is employed to adjust the charging process.
摘要翻译： 一种具有次级线圈的可植入医疗装置的充电系统。 充电系统包括外部电源，该外部电源具有至少一个初级线圈，可操作地耦合到初级线圈并且能够以特征在于充电参数的方式驱动它的调制电路，以及与调制电路通信并具有能力的传感器 感测在充电过程中指示需要调整充电参数的条件。 该参数可以变化，使得由传感器感测的数据满足阈值要求，其可以基于患者偏好，政府法规，卫生当局颁布的建议和/或与患者携带的另一装置相关联的要求 。 在一个实施例中，调节规定了最大磁场曝光，并且采用场限制电路来调节充电过程。
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公开(公告)号：US09333350B2
公开(公告)日：2016-05-10
申请号：US12425903
申请日：2009-04-17
申请人： Mark T. Rise , Jonathon E. Giftakis , Paul H. Stypulkowski , Timothy J. Denison , Nathan A. Torgerson
发明人： Mark T. Rise , Jonathon E. Giftakis , Paul H. Stypulkowski , Timothy J. Denison , Nathan A. Torgerson
CPC分类号： A61N1/36082 , A61B5/01 , A61B5/0488 , A61B5/08 , A61B5/0816 , A61B5/165 , A61B5/441 , A61B5/4836 , A61B5/7275 , G06F19/00 , G16H20/70 , G16H40/63
摘要： A therapy system for managing a psychiatric disorder of the patient may be controlled based on a patient mood state. Therapy may be delivered to a patient according to a therapy program, and a physiological parameter of the patient may be monitored during or after therapy delivery. The patient mood state may be determined based on the monitored physiological parameter, and the therapy delivery may be controlled based on the determined mood state. In some embodiments, the therapy delivery is stopped prior to determining the patient mood state and the therapy delivery is restarted upon detecting a negative mood state. In other embodiments, therapy delivery is delivered until a positive mood state is detected, at which point the therapy delivery may be stopped.
摘要翻译： 可以基于患者情绪状态来控制用于管理患者精神障碍的治疗系统。 治疗可以根据治疗程序递送到患者，并且可以在治疗递送期间或之后监测患者的生理参数。 可以基于所监测的生理参数来确定患者情绪状态，并且可以基于所确定的情绪状态来控制治疗递送。 在一些实施例中，在确定患者情绪状态之前停止治疗递送，并且在检测到负情绪状态时重新开始治疗递送。 在其它实施方案中，递送治疗递送直到检测到正状态，此时可以停止治疗递送。
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公开(公告)号：US09327070B2
公开(公告)日：2016-05-03
申请号：US12433501
申请日：2009-04-30
CPC分类号： A61M5/14276 , A61B5/11 , A61B5/1116 , A61B5/7475 , A61B2562/0219 , A61M2005/14208 , A61M2210/0693 , A61M2210/1053 , A61M2210/1078 , A61M2230/62 , A61N1/36071 , A61N1/36139 , A61N1/37247
摘要： This disclosure describes techniques implemented by a medical device, such as an implantable medical device (IMD). The IMD may be configured to detect a posture state of a patient, and deliver posture-responsive therapy. In particular, the IMD not only detects the posture state of a patient, but also detects timing associated with the detected posture state, such as the time of day, the day of the week, or a specific time of day associated with a specific day. In this way, the posture-responsive therapy delivered by the IMD may be dependent not only on the posture state of the patient, but also on the timing associated with the posture state. The same posture state, therefore, may result in different types of therapy to the patient if the same posture occurs at different times of the day.
摘要翻译： 本公开描述了由诸如可植入医疗装置（IMD）的医疗装置实现的技术。 IMD可以被配置为检测患者的姿势状态，并且提供姿势响应治疗。 特别地，IMD不仅检测患者的姿势状态，而且检测与检测到的姿势状态相关联的定时，例如一天中的时间，一周中的一天或与特定日期相关联的特定时间 。 以这种方式，由IMD递送的姿势响应治疗不仅取决于患者的姿势状态，而且还取决于与姿势状态相关的时间。 因此，如果在一天的不同时间发生相同的姿势，那么相同的姿势状态可能导致对患者的不同类型的治疗。
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公开(公告)号：US09149635B2
公开(公告)日：2015-10-06
申请号：US13458109
申请日：2012-04-27
申请人： Timothy J. Denison , Robert W. Hocken, Jr. , Gabriela C. Molnar , Wesley A. Santa , Jalpa S. Shah , Larry E. Tyler
发明人： Timothy J. Denison , Robert W. Hocken, Jr. , Gabriela C. Molnar , Wesley A. Santa , Jalpa S. Shah , Larry E. Tyler
CPC分类号： A61N1/36125 , A61N1/378 , A61N1/3787
摘要： This disclosure describes techniques for generating stimulation current pulses that have differing pulse shapes in a medical device. A circuit architecture is described that is configured to charge a capacitor to an initial amount of charge, modulate the amount of charge stored in the capacitor based on a control signal, and generate a stimulation current pulse that has an amplitude based on the amount charge stored in the capacitor. The circuit architecture may be configured to generate complex pulse shapes, such as, e.g., steps, ramps, bursts, and combinations thereof.
摘要翻译： 本公开描述了用于在医疗装置中产生具有不同脉冲形状的刺激电流脉冲的技术。 描述了一种电路架构，其被配置为基于控制信号对电容器充电至初始电荷量，并且基于控制信号调制存储在电容器中的电荷量，并且产生具有基于存储的电荷量的幅度的刺激电流脉冲 在电容器中。 电路架构可以被配置为产生复数脉冲形状，例如步骤，斜坡，脉冲串及其组合。
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公开(公告)号：US08380314B2
公开(公告)日：2013-02-19
申请号：US11974931
申请日：2007-10-16
IPC分类号： A61N1/18
CPC分类号： A61N1/36139 , A61B5/048 , A61B5/4082 , A61B5/7475 , A61M5/14276 , A61M5/1723 , A61M2210/0693 , A61N1/36014 , A61N1/36017 , A61N1/36021 , A61N1/36025 , A61N1/3605 , A61N1/3606 , A61N1/36071 , A61N1/36082 , A61N1/37252 , G06F3/015
摘要： A patient controls the delivery of therapy through volitional inputs that are detected by a biosignal within the brain. The volitional patient input may be directed towards performing a specific physical or mental activity, such as moving a muscle or performing a mathematical calculation. In one embodiment, a biosignal detection module monitors an electroencephalogram (EEG) signal from within the brain of the patient and determines whether the EEG signal includes the biosignal. In one embodiment, the biosignal detection module analyzes one or more frequency components of the EEG signal. In this manner, the patient may adjust therapy delivery by providing a volitional input that is detected by brain signals, wherein the volitional input may not require the interaction with another device, thereby eliminating the need for an external programmer to adjust therapy delivery. Example therapies include electrical stimulation, drug delivery, and delivery of sensory cues.
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9.发明申请公开(公告)号：US20120123338A1
公开(公告)日：2012-05-17
申请号：US13387071
申请日：2011-06-16
IPC分类号： A61M5/142
CPC分类号： A61M5/14244 , A61M2005/14264 , A61M2205/332 , A61M2205/3368 , A61M2230/63
摘要： The invention relates to systems and methods for stabilizing therapeutic formulations used in medical devices. In particular, the invention relates to systems designed to inhibit the aggregation of therapeutic molecules such as polypeptides stored within a medication delivery device, for example polypeptide aggregation that can result from jostling the medication within a fluid medication reservoir. In embodiments of the invention, a damping system is operably connected to a fluid medication reservoir that is disposed within the housing of a device so as to inhibit the agitation of a fluid medication. Typically the damping system comprises one or more energy absorbing materials.
摘要翻译： 本发明涉及用于稳定医疗器械中使用的治疗剂型的系统和方法。 特别地，本发明涉及被设计用于抑制治疗分子（例如存储在药物递送装置内的多肽）的聚集的系统，例如可能由于在流体药物储存器内推挤药物而导致的多肽聚集。 在本发明的实施例中，阻尼系统可操作地连接到设置在装置的壳体内的流体药物储存器，以便抑制流体药物的搅动。 通常，阻尼系统包括一种或多种能量吸收材料。
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公开(公告)号：US20120035496A1
公开(公告)日：2012-02-09
申请号：US13264023
申请日：2010-04-20
IPC分类号： A61B5/053
CPC分类号： A61N1/36007 , A61B5/053 , A61B5/1116 , A61B5/204 , A61B5/686 , A61B5/6883 , A61B5/7203 , A61B2560/0462 , A61B2562/0219
摘要： This disclosure provides techniques for bladder sensing. In accordance with the techniques described in this disclosure, a device may measure the impedance of a bladder, determine the posture of a patient, and determine a status of the bladder based on the impedance and posture.
摘要翻译： 本公开提供了用于膀胱感测的技术。 根据本公开中描述的技术，装置可以测量膀胱的阻抗，确定患者的姿势，并且基于阻抗和姿势来确定膀胱的状态。
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